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Term:glycerophosphate shuttle
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Accession:GO:0006127 term browser browse the term
Definition:The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle.
Synonyms:xref: MetaCyc:PWY-6118

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glycerophosphate shuttle term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GPD1 glycerol-3-phosphate dehydrogenase 1 JBrowse link 5 16,008,179 16,021,676 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14973
    metabolic process 9064
      NADH metabolic process 15
        NADH oxidation 3
          glycerophosphate shuttle 1
Path 2
Term Annotations click to browse term
  biological_process 14973
    cellular process 14114
      cellular metabolic process 8271
        generation of precursor metabolites and energy 317
          energy derivation by oxidation of organic compounds 183
            cellular respiration 124
              respiratory electron transport chain 70
                glycerophosphate shuttle 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.