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ONTOLOGY REPORT - ANNOTATIONS


Term:purine nucleobase metabolic process
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Accession:GO:0006144 term browser browse the term
Definition:The chemical reactions and pathways involving purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.
Synonyms:exact_synonym: purine base metabolic process;   purine base metabolism
 narrow_synonym: purine metabolic process;   purine metabolism


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purine nucleobase metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acp3 acid phosphatase 3 JBrowse link 8 112,838,574 112,884,062 RGD:1600115
RGD:1624291
G Gmpr guanosine monophosphate reductase JBrowse link 17 19,543,274 19,580,929 RGD:1600115
G Gmpr2 guanosine monophosphate reductase 2 JBrowse link 15 34,352,857 34,362,074 RGD:1600115
G Prps1 phosphoribosyl pyrophosphate synthetase 1 JBrowse link X 111,798,233 111,820,270 RGD:1624291
G RGD1309350 similar to transthyretin (4L369) JBrowse link 1 213,577,202 213,580,598 RGD:13792537
G Ttr transthyretin JBrowse link 18 15,532,963 15,542,180 RGD:13792537
adenine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase JBrowse link 11 31,780,477 31,805,728 RGD:13792537
adenine metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ak1 adenylate kinase 1 JBrowse link 3 11,652,143 11,659,135 RGD:5490217
G Ak2 adenylate kinase 2 JBrowse link 5 147,185,474 147,204,050 RGD:5490217
G Aprt adenine phosphoribosyl transferase JBrowse link 19 55,387,288 55,389,256 RGD:1624291
G Hprt1 hypoxanthine phosphoribosyltransferase 1 JBrowse link X 158,196,640 158,228,815 RGD:1624291
adenine salvage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aprt adenine phosphoribosyl transferase JBrowse link 19 55,387,288 55,389,256 RGD:1624291
RGD:13792537
G Hprt1 hypoxanthine phosphoribosyltransferase 1 JBrowse link X 158,196,640 158,228,815 RGD:1624291
RGD:13792537
G LOC103689983 hypoxanthine-guanine phosphoribosyltransferase JBrowse link X 158,623,231 158,655,277 RGD:13792537
guanine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gda guanine deaminase JBrowse link 1 238,982,542 239,057,663 RGD:1600115
guanine metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gda guanine deaminase JBrowse link 1 238,982,542 239,057,663 RGD:13792537
G Kdm1a lysine demethylase 1A JBrowse link 5 154,909,003 154,965,171 RGD:9588315
guanine salvage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hprt1 hypoxanthine phosphoribosyltransferase 1 JBrowse link X 158,196,640 158,228,815 RGD:1624291
RGD:13792537
RGD:1600115
G LOC103689983 hypoxanthine-guanine phosphoribosyltransferase JBrowse link X 158,623,231 158,655,277 RGD:1600115
RGD:13792537
G Prtfdc1 phosphoribosyl transferase domain containing 1 JBrowse link 17 87,926,242 88,037,040 RGD:1624291
hypoxanthine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ada adenosine deaminase JBrowse link 3 160,115,840 160,139,947 RGD:1624291
G Prps1 phosphoribosyl pyrophosphate synthetase 1 JBrowse link X 111,798,233 111,820,270 RGD:1624291
hypoxanthine metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hprt1 hypoxanthine phosphoribosyltransferase 1 JBrowse link X 158,196,640 158,228,815 RGD:1580844
RGD:13792537
RGD:1624291
G LOC103689983 hypoxanthine-guanine phosphoribosyltransferase JBrowse link X 158,623,231 158,655,277 RGD:13792537
hypoxanthine oxidation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Xdh xanthine dehydrogenase JBrowse link 6 25,149,570 25,211,273 RGD:13210503
hypoxanthine salvage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ada adenosine deaminase JBrowse link 3 160,115,840 160,139,947 RGD:13792537
G Hprt1 hypoxanthine phosphoribosyltransferase 1 JBrowse link X 158,196,640 158,228,815 RGD:1624291
RGD:1600115
G LOC103689983 hypoxanthine-guanine phosphoribosyltransferase JBrowse link X 158,623,231 158,655,277 RGD:1600115
purine nucleobase biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ppat phosphoribosyl pyrophosphate amidotransferase JBrowse link 14 33,580,541 33,614,919 RGD:1600115
G Shmt1 serine hydroxymethyltransferase 1 JBrowse link 10 47,030,813 47,059,216 RGD:1624291
RGD:13792537
G Shmt2 serine hydroxymethyltransferase 2 JBrowse link 7 70,824,718 70,829,822 RGD:13792537
purine nucleobase catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dpyd dihydropyrimidine dehydrogenase JBrowse link 2 221,823,692 222,694,627 RGD:1624291
RGD:1600115
G Uox urate oxidase JBrowse link 2 252,452,282 252,488,497 RGD:730101
xanthine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ada adenosine deaminase JBrowse link 3 160,115,840 160,139,947 RGD:1624291
xanthine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aox1 aldehyde oxidase 1 JBrowse link 9 64,929,682 65,007,872 RGD:13792537
G Aox2 aldehyde oxidase 2 JBrowse link 9 65,175,455 65,265,149 RGD:13792537
G Aox3 aldehyde oxidase 3 JBrowse link 9 65,013,831 65,099,433 RGD:13792537
G Aox4 aldehyde oxidase 4 JBrowse link 9 65,110,330 65,167,188 RGD:13792537
G Xdh xanthine dehydrogenase JBrowse link 6 25,149,570 25,211,273 RGD:8553512
RGD:13792537
RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12096
      nitrogen compound metabolic process 10192
        organonitrogen compound metabolic process 7094
          nucleobase metabolic process 48
            purine nucleobase metabolic process 26
              adenine metabolic process + 6
              guanine metabolic process + 5
              hypoxanthine metabolic process + 5
              negative regulation of purine nucleobase metabolic process 0
              positive regulation of purine nucleobase metabolic process 0
              purine nucleobase biosynthetic process + 10
              purine nucleobase catabolic process + 8
              regulation of purine nucleobase metabolic process + 0
              xanthine metabolic process + 6
Path 2
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12096
      nitrogen compound metabolic process 10192
        cellular nitrogen compound metabolic process 6542
          nucleobase-containing compound metabolic process 5344
            nucleobase-containing small molecule metabolic process 582
              nucleobase metabolic process 48
                purine nucleobase metabolic process 26
                  adenine metabolic process + 6
                  guanine metabolic process + 5
                  hypoxanthine metabolic process + 5
                  negative regulation of purine nucleobase metabolic process 0
                  positive regulation of purine nucleobase metabolic process 0
                  purine nucleobase biosynthetic process + 10
                  purine nucleobase catabolic process + 8
                  regulation of purine nucleobase metabolic process + 0
                  xanthine metabolic process + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.