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ONTOLOGY REPORT - ANNOTATIONS


Term:purine nucleobase metabolic process
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Accession:GO:0006144 term browser browse the term
Definition:The chemical reactions and pathways involving purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.
Synonyms:exact_synonym: purine base metabolic process;   purine base metabolism
 narrow_synonym: purine metabolic process;   purine metabolism


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purine nucleobase metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP3 acid phosphatase 3 ISO (MGI:MGI:3849266|PMID:18940592) UniProtKB PMID:18940592 MGI:MGI:3849266 NCBI chr 3:129,392,396...129,465,962
Ensembl chr 3:136,713,816...136,764,655
JBrowse link
G PRPS1 phosphoribosyl pyrophosphate synthetase 1 ISO (PMID:8253776) UniProtKB PMID:8253776 NCBI chr  X:96,720,988...96,743,594
Ensembl chr  X:107,094,898...107,117,117
JBrowse link
adenine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APRT adenine phosphoribosyltransferase ISO (MGI:MGI:83266|PMID:8894695)
(MGI:MGI:80735|PMID:8643571), (MGI:MGI:83266|PMID:8894695)
MGI PMID:8643571, PMID:8894695 MGI:MGI:80735, MGI:MGI:83266 NCBI chr16:69,522,628...69,525,138
Ensembl chr16:89,179,020...89,181,504
JBrowse link
G HPRT1 hypoxanthine phosphoribosyltransferase 1 ISO (MGI:MGI:83266|PMID:8894695) MGI PMID:8894695 MGI:MGI:83266 NCBI chr  X:123,609,248...123,650,102
Ensembl chr  X:133,916,681...133,948,197
JBrowse link
adenine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APRT adenine phosphoribosyltransferase ISO (MGI:MGI:85816|PMID:8864750) MGI PMID:8864750 MGI:MGI:85816 NCBI chr16:69,522,628...69,525,138
Ensembl chr16:89,179,020...89,181,504
JBrowse link
G HPRT1 hypoxanthine phosphoribosyltransferase 1 ISO (MGI:MGI:1331314|PMID:10037486) MGI PMID:10037486 MGI:MGI:1331314 NCBI chr  X:123,609,248...123,650,102
Ensembl chr  X:133,916,681...133,948,197
JBrowse link
guanine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KDM1A lysine demethylase 1A ISO RGD PMID:20418916 RGD:9588315 NCBI chr 1:22,205,624...22,269,571
Ensembl chr 1:23,153,066...23,217,692
JBrowse link
guanine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPRT1 hypoxanthine phosphoribosyltransferase 1 ISO (PMID:19527031)
(MGI:MGI:1331314|PMID:10037486)
UniProtKB
MGI
PMID:10037486, PMID:19527031 MGI:MGI:1331314 NCBI chr  X:123,609,248...123,650,102
Ensembl chr  X:133,916,681...133,948,197
JBrowse link
G PRTFDC1 phosphoribosyl transferase domain containing 1 NOT ISO (PMID:21054786) UniProtKB PMID:21054786 NCBI chr10:25,023,015...25,127,770
Ensembl chr10:25,393,227...25,497,054
JBrowse link
hypoxanthine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase ISO (MGI:MGI:3640719|PMID:10720488) MGI PMID:10720488 MGI:MGI:3640719 NCBI chr20:40,950,238...40,982,481
Ensembl chr20:42,044,613...42,076,868
JBrowse link
G PRPS1 phosphoribosyl pyrophosphate synthetase 1 ISO (PMID:17701896) UniProtKB PMID:17701896 NCBI chr  X:96,720,988...96,743,594
Ensembl chr  X:107,094,898...107,117,117
JBrowse link
hypoxanthine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPRT1 hypoxanthine phosphoribosyltransferase 1 ISO (MGI:MGI:63605|PMID:3029599)
(MGI:MGI:1331314|PMID:10037486)
(PMID:9824441)
RGD
MGI
UniProtKB
PMID:3029599, PMID:6206848, PMID:9824441, PMID:10037486 MGI:MGI:1331314, MGI:MGI:63605, RGD:1580844 NCBI chr  X:123,609,248...123,650,102
Ensembl chr  X:133,916,681...133,948,197
JBrowse link
hypoxanthine oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G XDH xanthine dehydrogenase ISO RGD PMID:232638 RGD:13210503 NCBI chr2A:31,356,011...31,435,111
Ensembl chr2A:31,425,183...31,504,455
JBrowse link
hypoxanthine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPRT1 hypoxanthine phosphoribosyltransferase 1 ISO (PMID:19527031) UniProtKB PMID:19527031 NCBI chr  X:123,609,248...123,650,102
Ensembl chr  X:133,916,681...133,948,197
JBrowse link
purine nucleobase biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SHMT1 serine hydroxymethyltransferase 1 ISO (PMID:11516159) UniProtKB PMID:11516159 NCBI chr17:32,870,949...32,905,690
Ensembl chr17:37,849,206...37,884,220
JBrowse link
purine nucleobase catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DPYD dihydropyrimidine dehydrogenase ISO (PMID:11988088) UniProtKB PMID:11988088 NCBI chr 1:99,736,145...100,576,663
Ensembl chr 1:98,457,934...99,300,100
JBrowse link
xanthine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase ISO (MGI:MGI:3640719|PMID:10720488) MGI PMID:10720488 MGI:MGI:3640719 NCBI chr20:40,950,238...40,982,481
Ensembl chr20:42,044,613...42,076,868
JBrowse link
xanthine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G XDH xanthine dehydrogenase ISO (PMID:17301077), (PMID:8670112)
PMID:15878860
UniProtKB
UniProt
PMID:8670112, PMID:15878860, PMID:17301077 RGD:8553512 NCBI chr2A:31,356,011...31,435,111
Ensembl chr2A:31,425,183...31,504,455
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12529
    metabolic process 7962
      nitrogen compound metabolic process 6668
        organonitrogen compound metabolic process 4630
          nucleobase metabolic process 20
            purine nucleobase metabolic process 10
              adenine metabolic process + 2
              guanine metabolic process + 3
              hypoxanthine metabolic process + 4
              negative regulation of purine nucleobase metabolic process 0
              positive regulation of purine nucleobase metabolic process 0
              purine nucleobase biosynthetic process + 6
              purine nucleobase catabolic process + 2
              regulation of purine nucleobase metabolic process + 0
              xanthine metabolic process + 2
Path 2
Term Annotations click to browse term
  biological_process 12529
    metabolic process 7962
      nitrogen compound metabolic process 6668
        cellular nitrogen compound metabolic process 4215
          nucleobase-containing compound metabolic process 3691
            nucleobase-containing small molecule metabolic process 376
              nucleobase metabolic process 20
                purine nucleobase metabolic process 10
                  adenine metabolic process + 2
                  guanine metabolic process + 3
                  hypoxanthine metabolic process + 4
                  negative regulation of purine nucleobase metabolic process 0
                  positive regulation of purine nucleobase metabolic process 0
                  purine nucleobase biosynthetic process + 6
                  purine nucleobase catabolic process + 2
                  regulation of purine nucleobase metabolic process + 0
                  xanthine metabolic process + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.