Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:purine nucleobase metabolic process
go back to main search page
Accession:GO:0006144 term browser browse the term
Definition:The chemical reactions and pathways involving purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.
Synonyms:exact_synonym: purine base metabolic process;   purine base metabolism
 narrow_synonym: purine metabolic process;   purine metabolism


show annotations for term's descendants           Sort by:
 
purine nucleobase metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP3 acid phosphatase 3 IEA Ensembl GO_REF:0000107 NCBI chr23:29,294,641...29,353,970
Ensembl chr23:29,294,843...29,343,499
JBrowse link
G GMPR guanosine monophosphate reductase IEA UniProt GO_REF:0000043 NCBI chr35:15,400,937...15,449,157
Ensembl chr35:15,401,003...15,448,022
JBrowse link
G GMPR2 guanosine monophosphate reductase 2 IEA UniProt GO_REF:0000043 NCBI chr 8:4,213,238...4,220,740
Ensembl chr 8:4,213,373...4,220,740
JBrowse link
G PRPS1 phosphoribosyl pyrophosphate synthetase 1 ISO (PMID:8253776) UniProtKB PMID:8253776 NCBI chr  X:81,150,537...81,171,521
Ensembl chr  X:81,150,536...81,212,689
JBrowse link
G TTR transthyretin IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:57,940,354...57,947,084
Ensembl chr 7:57,914,381...57,947,058
JBrowse link
G UOX urate oxidase IEA UniProt GO_REF:0000043 NCBI chr 6:63,482,384...63,513,538
Ensembl chr 6:63,436,236...63,513,478
JBrowse link
G URAD ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase IEA UniProt GO_REF:0000043 NCBI chr25:11,682,304...11,693,143
Ensembl chr25:11,581,206...11,692,284
JBrowse link
adenine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100856570 trifunctional purine biosynthetic protein adenosine-3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr31:28,133,546...28,165,595 JBrowse link
G LOC487740 trifunctional purine biosynthetic protein adenosine-3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr31:29,032,399...29,063,706 JBrowse link
adenine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APRT adenine phosphoribosyltransferase ISO (MGI:MGI:80735|PMID:8643571), (MGI:MGI:83266|PMID:8894695)
(MGI:MGI:83266|PMID:8894695)
MGI PMID:8643571, PMID:8894695 MGI:MGI:80735, MGI:MGI:83266 NCBI chr 5:64,563,154...64,565,537
Ensembl chr 5:64,563,192...64,565,445
JBrowse link
G HPRT1 hypoxanthine phosphoribosyltransferase 1 ISO (MGI:MGI:83266|PMID:8894695) MGI PMID:8894695 MGI:MGI:83266 NCBI chr  X:105,115,732...105,153,702
Ensembl chr  X:105,115,732...105,153,702
JBrowse link
adenine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APRT adenine phosphoribosyltransferase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:64,563,154...64,565,537
Ensembl chr 5:64,563,192...64,565,445
JBrowse link
G HPRT1 hypoxanthine phosphoribosyltransferase 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:105,115,732...105,153,702
Ensembl chr  X:105,115,732...105,153,702
JBrowse link
guanine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GDA guanine deaminase IEA UniProt GO_REF:0000041 NCBI chr 1:85,506,598...85,586,212
Ensembl chr 1:85,444,917...85,586,163
JBrowse link
guanine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GDA guanine deaminase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:85,506,598...85,586,212
Ensembl chr 1:85,444,917...85,586,163
JBrowse link
G KDM1A lysine demethylase 1A ISO RGD PMID:20418916 RGD:9588315 NCBI chr 2:76,313,742...76,375,716
Ensembl chr 2:76,156,434...76,375,632
JBrowse link
guanine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPRT1 hypoxanthine phosphoribosyltransferase 1 ISS
IBA
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000024 NCBI chr  X:105,115,732...105,153,702
Ensembl chr  X:105,115,732...105,153,702
JBrowse link
G PRTFDC1 phosphoribosyl transferase domain containing 1 NOT ISO (PMID:21054786) UniProtKB PMID:21054786 NCBI chr 2:8,551,008...8,643,710
Ensembl chr 2:8,559,319...8,642,533
JBrowse link
hypoxanthine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase IEA Ensembl GO_REF:0000107 NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160
JBrowse link
G PRPS1 phosphoribosyl pyrophosphate synthetase 1 ISO (PMID:17701896) UniProtKB PMID:17701896 NCBI chr  X:81,150,537...81,171,521
Ensembl chr  X:81,150,536...81,212,689
JBrowse link
hypoxanthine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPRT1 hypoxanthine phosphoribosyltransferase 1 ISS
IBA
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000024 NCBI chr  X:105,115,732...105,153,702
Ensembl chr  X:105,115,732...105,153,702
JBrowse link
hypoxanthine oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G XDH xanthine dehydrogenase ISO RGD PMID:232638 RGD:13210503 NCBI chr17:24,900,708...24,960,748
Ensembl chr17:24,901,447...24,971,935
JBrowse link
hypoxanthine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160
JBrowse link
G HPRT1 hypoxanthine phosphoribosyltransferase 1 ISS UniProtKB GO_REF:0000024 NCBI chr  X:105,115,732...105,153,702
Ensembl chr  X:105,115,732...105,153,702
JBrowse link
purine nucleobase biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100856570 trifunctional purine biosynthetic protein adenosine-3 IEA UniProt GO_REF:0000104 NCBI chr31:28,133,546...28,165,595 JBrowse link
G PPAT phosphoribosyl pyrophosphate amidotransferase IEA InterPro GO_REF:0000002 NCBI chr13:48,618,460...48,656,164
Ensembl chr13:48,620,714...48,655,780
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:41,221,531...41,248,653
Ensembl chr 5:41,221,562...41,253,166
JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:1,357,347...1,362,511
Ensembl chr10:1,356,706...1,362,305
JBrowse link
purine nucleobase catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DPYD dihydropyrimidine dehydrogenase IEA Ensembl GO_REF:0000107 NCBI chr 6:51,789,786...52,564,802
Ensembl chr 6:51,814,573...52,580,923
JBrowse link
xanthine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase IEA Ensembl GO_REF:0000107 NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160
JBrowse link
xanthine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AOX2 aldehyde oxidase 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr37:9,912,731...9,992,322
Ensembl chr37:9,913,675...9,992,319
JBrowse link
G AOX4 aldehyde oxidase 4 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr37:9,837,901...9,902,076
Ensembl chr37:9,838,063...9,901,586
JBrowse link
G XDH xanthine dehydrogenase IEA
IBA
(PMID:21873635) Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr17:24,900,708...24,960,748
Ensembl chr17:24,901,447...24,971,935
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16162
    metabolic process 10639
      nitrogen compound metabolic process 8980
        organonitrogen compound metabolic process 6195
          nucleobase metabolic process 42
            purine nucleobase metabolic process 22
              adenine metabolic process + 4
              guanine metabolic process + 4
              hypoxanthine metabolic process + 4
              negative regulation of purine nucleobase metabolic process 0
              positive regulation of purine nucleobase metabolic process 0
              purine nucleobase biosynthetic process + 10
              purine nucleobase catabolic process + 5
              regulation of purine nucleobase metabolic process + 0
              xanthine metabolic process + 4
Path 2
Term Annotations click to browse term
  biological_process 16162
    metabolic process 10639
      nitrogen compound metabolic process 8980
        cellular nitrogen compound metabolic process 5695
          nucleobase-containing compound metabolic process 4907
            nucleobase-containing small molecule metabolic process 540
              nucleobase metabolic process 42
                purine nucleobase metabolic process 22
                  adenine metabolic process + 4
                  guanine metabolic process + 4
                  hypoxanthine metabolic process + 4
                  negative regulation of purine nucleobase metabolic process 0
                  positive regulation of purine nucleobase metabolic process 0
                  purine nucleobase biosynthetic process + 10
                  purine nucleobase catabolic process + 5
                  regulation of purine nucleobase metabolic process + 0
                  xanthine metabolic process + 4
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.