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ONTOLOGY REPORT - ANNOTATIONS


Term:purine nucleobase metabolic process
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Accession:GO:0006144 term browser browse the term
Definition:The chemical reactions and pathways involving purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.
Synonyms:exact_synonym: purine base metabolic process;   purine base metabolism
 narrow_synonym: purine metabolic process;   purine metabolism


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purine nucleobase metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acpp acid phosphatase, prostate IMP (MGI:MGI:3849266|PMID:18940592) UniProtKB PMID:18940592 MGI:MGI:3849266 NCBI chr 9:104,288,240...104,337,722
Ensembl chr 9:104,288,251...104,337,748
JBrowse link
G Gmpr guanosine monophosphate reductase IEA UniProtKB GO_REF:0000004, MGI:MGI:1354194 NCBI chr13:45,507,428...45,546,386
Ensembl chr13:45,507,444...45,553,800
JBrowse link
G Gmpr2 guanosine monophosphate reductase 2 IEA UniProtKB GO_REF:0000004, MGI:MGI:1354194 NCBI chr14:55,672,235...55,687,861
Ensembl chr14:55,671,941...55,679,200
JBrowse link
G Prps1 phosphoribosyl pyrophosphate synthetase 1 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr  X:140,456,603...140,476,140
Ensembl chr  X:140,456,613...140,476,140
JBrowse link
G Ttr transthyretin IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr18:20,664,209...20,674,326
Ensembl chr18:20,665,280...20,674,321
JBrowse link
G Uox urate oxidase TAS (MGI:MGI:2137799|PMID:11461119) MGI PMID:11461119 MGI:MGI:2137799 NCBI chr 3:146,597,149...146,631,483
Ensembl chr 3:146,570,426...146,632,305
JBrowse link
G Urad ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5) decarboxylase IEA UniProtKB GO_REF:0000004, MGI:MGI:1354194 NCBI chr 5:147,314,984...147,322,440
Ensembl chr 5:147,314,984...147,322,440
JBrowse link
G Urah urate (5-hydroxyiso-) hydrolase IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr 7:140,834,958...140,837,971
Ensembl chr 7:140,835,018...140,837,966
JBrowse link
adenine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gart phosphoribosylglycinamide formyltransferase IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr16:91,621,395...91,646,972
Ensembl chr16:91,621,186...91,646,952
JBrowse link
adenine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aprt adenine phosphoribosyl transferase IC
IMP
IGI
(MGI:MGI:54294|PMID:1235912)
(MGI:MGI:80735|PMID:8643571), (MGI:MGI:83266|PMID:8894695)
(MGI:MGI:83266|PMID:8894695)
MGI PMID:1235912, PMID:8643571, PMID:8894695 MGI:MGI:54294, MGI:MGI:80735, MGI:MGI:83266 NCBI chr 8:122,574,637...122,576,907
Ensembl chr 8:122,574,635...122,576,909
JBrowse link
G Hprt hypoxanthine guanine phosphoribosyl transferase IGI
IMP
(MGI:MGI:83266|PMID:8894695) MGI PMID:8894695 MGI:MGI:83266 NCBI chr  X:52,988,078...53,021,660
Ensembl chr  X:52,988,137...53,021,659
JBrowse link
adenine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aprt adenine phosphoribosyl transferase IMP
IBA
(MGI:MGI:85816|PMID:8864750)
(MGI:MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:8864750, PMID:21873635 MGI:MGI:6201960, MGI:MGI:85816 NCBI chr 8:122,574,637...122,576,907
Ensembl chr 8:122,574,635...122,576,909
JBrowse link
G Hprt hypoxanthine guanine phosphoribosyl transferase IMP
IBA
(MGI:MGI:1331314|PMID:10037486)
(MGI:MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:10037486, PMID:21873635 MGI:MGI:1331314, MGI:MGI:6201960 NCBI chr  X:52,988,078...53,021,660
Ensembl chr  X:52,988,137...53,021,659
JBrowse link
guanine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gda guanine deaminase IEA UniProtKB GO_REF:0000002, MGI:MGI:2152098 NCBI chr19:21,391,307...21,472,661
Ensembl chr19:21,391,307...21,473,445
JBrowse link
guanine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gda guanine deaminase IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr19:21,391,307...21,472,661
Ensembl chr19:21,391,307...21,473,445
JBrowse link
G Kdm1a lysine (K)-specific demethylase 1A ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr 4:136,550,533...136,602,787
Ensembl chr 4:136,550,540...136,602,723
JBrowse link
guanine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gm13377 predicted gene 13377 NOT ISO (PMID:21054786) UniProtKB PMID:21054786 NCBI chr 2:21,044,809...21,139,682
Ensembl chr 2:21,044,808...21,141,954
JBrowse link
G Hprt hypoxanthine guanine phosphoribosyl transferase IMP
IBA
ISO
(MGI:MGI:1331314|PMID:10037486)
(MGI:MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:10037486, PMID:21873635 GO_REF:0000096, MGI:MGI:1331314, MGI:MGI:4834177, MGI:MGI:6201960 NCBI chr  X:52,988,078...53,021,660
Ensembl chr  X:52,988,137...53,021,659
JBrowse link
hypoxanthine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase IMP (MGI:MGI:3640719|PMID:10720488) MGI PMID:10720488 MGI:MGI:3640719 NCBI chr 2:163,726,571...163,750,239
Ensembl chr 2:163,726,584...163,750,239
JBrowse link
G Prps1 phosphoribosyl pyrophosphate synthetase 1 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr  X:140,456,603...140,476,140
Ensembl chr  X:140,456,613...140,476,140
JBrowse link
hypoxanthine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hprt hypoxanthine guanine phosphoribosyl transferase IC
IBA
ISO
IMP
(MGI:MGI:54294|PMID:1235912)
(MGI:MGI:6201960|PMID:21873635)
(MGI:MGI:1331314|PMID:10037486)
(MGI:MGI:63605|PMID:3029599)
MGI
GO_Central
RGD
PMID:1235912, PMID:3029599, PMID:10037486, PMID:21873635 GO_REF:0000096, MGI:MGI:1331314, MGI:MGI:4417868, MGI:MGI:4834177, MGI:MGI:54294, MGI:MGI:6201960, MGI:MGI:63605 NCBI chr  X:52,988,078...53,021,660
Ensembl chr  X:52,988,137...53,021,659
JBrowse link
hypoxanthine oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Xdh xanthine dehydrogenase ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr17:73,883,895...73,950,397
Ensembl chr17:73,883,895...73,950,196
JBrowse link
hypoxanthine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr 2:163,726,571...163,750,239
Ensembl chr 2:163,726,584...163,750,239
JBrowse link
G Hprt hypoxanthine guanine phosphoribosyl transferase ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr  X:52,988,078...53,021,660
Ensembl chr  X:52,988,137...53,021,659
JBrowse link
purine nucleobase biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gart phosphoribosylglycinamide formyltransferase IEA UniProt GO_REF:0000002, MGI:MGI:2152098 NCBI chr16:91,621,395...91,646,972
Ensembl chr16:91,621,186...91,646,952
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 (soluble) ISO
IBA
(MGI:MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096, MGI:MGI:4834177, MGI:MGI:6201960 NCBI chr11:60,788,897...60,811,265
Ensembl chr11:60,788,104...60,811,718
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 (mitochondrial) IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr10:127,517,123...127,522,444
Ensembl chr10:127,517,123...127,522,444
JBrowse link
purine nucleobase catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpyd dihydropyrimidine dehydrogenase ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 3:118,562,109...119,432,924
Ensembl chr 3:118,562,129...119,432,924
JBrowse link
xanthine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase IMP (MGI:MGI:3640719|PMID:10720488) MGI PMID:10720488 MGI:MGI:3640719 NCBI chr 2:163,726,571...163,750,239
Ensembl chr 2:163,726,584...163,750,239
JBrowse link
xanthine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aox1 aldehyde oxidase 1 IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr 1:58,029,809...58,106,410
Ensembl chr 1:58,029,931...58,106,413
JBrowse link
G Aox2 aldehyde oxidase 2 IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr 1:58,278,326...58,379,264
Ensembl chr 1:58,278,326...58,380,259
JBrowse link
G Aox3 aldehyde oxidase 3 IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr 1:58,113,135...58,202,221
Ensembl chr 1:58,113,130...58,200,698
JBrowse link
G Aox4 aldehyde oxidase 4 IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr 1:58,210,397...58,268,600
Ensembl chr 1:58,210,397...58,268,597
JBrowse link
G Xdh xanthine dehydrogenase ISO
IBA
(MGI:MGI:6201960|PMID:21873635) RGD
GO_Central
MGI
PMID:21873635 GO_REF:0000096, MGI:MGI:4417868, MGI:MGI:4834177, MGI:MGI:6201960 NCBI chr17:73,883,895...73,950,397
Ensembl chr17:73,883,895...73,950,196
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23369
    metabolic process 11273
      nitrogen compound metabolic process 9340
        organonitrogen compound metabolic process 6247
          nucleobase metabolic process 44
            purine nucleobase metabolic process 23
              adenine metabolic process + 3
              guanine metabolic process + 4
              hypoxanthine metabolic process + 4
              negative regulation of purine nucleobase metabolic process 0
              positive regulation of purine nucleobase metabolic process 0
              purine nucleobase biosynthetic process + 8
              purine nucleobase catabolic process + 7
              regulation of purine nucleobase metabolic process + 0
              xanthine metabolic process + 6
Path 2
Term Annotations click to browse term
  biological_process 23369
    metabolic process 11273
      nitrogen compound metabolic process 9340
        cellular nitrogen compound metabolic process 5964
          nucleobase-containing compound metabolic process 5182
            nucleobase-containing small molecule metabolic process 518
              nucleobase metabolic process 44
                purine nucleobase metabolic process 23
                  adenine metabolic process + 3
                  guanine metabolic process + 4
                  hypoxanthine metabolic process + 4
                  negative regulation of purine nucleobase metabolic process 0
                  positive regulation of purine nucleobase metabolic process 0
                  purine nucleobase biosynthetic process + 8
                  purine nucleobase catabolic process + 7
                  regulation of purine nucleobase metabolic process + 0
                  xanthine metabolic process + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.