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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA ligation
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Accession:GO:0006266 term browser browse the term
Definition:The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.


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DNA ligation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aptx aprataxin JBrowse link 5 56,987,714 57,009,481 RGD:1624291
G Lig1 DNA ligase 1 JBrowse link 1 75,356,212 75,394,757 RGD:13792537
G Lig3 DNA ligase 3 JBrowse link 10 70,134,734 70,158,051 RGD:1624291
RGD:13792537
G Lig4 DNA ligase 4 JBrowse link 16 85,331,771 85,339,496 RGD:1601271
RGD:1624291
G LOC100911727 DNA ligase 1-like JBrowse link 1 75,224,143 75,264,441 RGD:13792537
G Top2a DNA topoisomerase II alpha JBrowse link 10 86,901,467 86,930,947 RGD:1600115
RGD:1624291
G Xrcc4 X-ray repair cross complementing 4 JBrowse link 2 18,674,496 18,927,463 RGD:1624291
base-excision repair, DNA ligation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lig3 DNA ligase 3 JBrowse link 10 70,134,734 70,158,051 RGD:2302580
RGD:13792537
RGD:1624291
DNA ligation involved in DNA recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lig4 DNA ligase 4 JBrowse link 16 85,331,771 85,339,496 RGD:1624291
DNA ligation involved in DNA repair term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:1624291
G Hmgb2 high mobility group box 2 JBrowse link 16 36,077,615 36,080,191 RGD:1624291
G Lig1 DNA ligase 1 JBrowse link 1 75,356,212 75,394,757 RGD:1600115
RGD:13792537
G Lig3 DNA ligase 3 JBrowse link 10 70,134,734 70,158,051 RGD:13792537
G Lig4 DNA ligase 4 JBrowse link 16 85,331,771 85,339,496 RGD:1624291
RGD:13792537
G LOC100911727 DNA ligase 1-like JBrowse link 1 75,224,143 75,264,441 RGD:13792537
G LOC108349189 high mobility group protein B1 pseudogene JBrowse link X 115,351,012 115,351,755 RGD:1600115
G Paxx PAXX, non-homologous end joining factor JBrowse link 3 2,678,987 2,681,668 RGD:1624291
RGD:13792537
G Xrcc4 X-ray repair cross complementing 4 JBrowse link 2 18,674,496 18,927,463 RGD:1624291
RGD:13792537
positive regulation of DNA ligase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:1624291
G Xrcc1 X-ray repair cross complementing 1 JBrowse link 1 81,412,635 81,441,680 RGD:1624291
positive regulation of DNA ligation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aplf aprataxin and PNKP like factor JBrowse link 4 119,514,822 119,568,764 RGD:1624291
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:10449519
G Parp3 poly (ADP-ribose) polymerase family, member 3 JBrowse link 8 115,173,440 115,179,543 RGD:1624291
G Rad51 RAD51 recombinase JBrowse link 3 110,918,240 110,942,920 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    cellular process 18617
      cellular metabolic process 10917
        cellular macromolecule metabolic process 8392
          DNA metabolic process 911
            DNA ligation 15
              DNA ligation involved in DNA recombination 1
              DNA ligation involved in DNA repair + 9
              DNA-dependent DNA replication DNA ligation + 0
              negative regulation of DNA ligation + 0
              positive regulation of DNA ligation + 5
              regulation of DNA ligation + 5
Path 2
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12096
      cellular metabolic process 10917
        cellular nitrogen compound metabolic process 6542
          nucleobase-containing compound metabolic process 5344
            nucleic acid metabolic process 4850
              DNA metabolic process 911
                DNA ligation 15
                  DNA ligation involved in DNA recombination 1
                  DNA ligation involved in DNA repair + 9
                  DNA-dependent DNA replication DNA ligation + 0
                  negative regulation of DNA ligation + 0
                  positive regulation of DNA ligation + 5
                  regulation of DNA ligation + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.