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ONTOLOGY REPORT - ANNOTATIONS


Term:RNA-dependent DNA biosynthetic process
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Accession:GO:0006278 term browser browse the term
Definition:A DNA biosynthetic process that uses RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strand.


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RNA-dependent DNA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tep1 telomerase associated protein 1 IC
IEA
PMID:9118230
GO_REF:0000108
GOC PMID:9118230 GO_REF:0000108, RGD:1299082 NCBI chr15:27,751,186...27,798,839
Ensembl chr15:27,751,180...27,798,839
JBrowse link
G Terf2 telomeric repeat binding factor 2 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr19:39,271,992...39,301,506
Ensembl chr19:39,272,499...39,300,893
JBrowse link
G Tert telomerase reverse transcriptase ISO (PMID:9398860) RGD PMID:9398860 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
negative regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor ISO
IBA
UniProtKB:Q9NUX5 (PMID:15181449), (PMID:15380063)
PMID:21873635
RGD PMID:15181449, PMID:15380063, PMID:21873635 RGD:13792537 NCBI chr19:37,665,289...37,668,043
Ensembl chr19:37,665,296...37,667,987
JBrowse link
G Ctc1 CST telomere replication complex component 1 ISO (PMID:22763445) RGD PMID:22763445 NCBI chr10:55,596,172...55,616,873
Ensembl chr10:55,596,148...55,616,889
JBrowse link
G Dcp2 decapping mRNA 2 ISO (PMID:26950371) RGD PMID:26950371 NCBI chr18:35,489,274...35,671,676
Ensembl chr18:35,489,274...35,672,291
JBrowse link
G Exosc10 exosome component 10 ISO (PMID:26950371) RGD PMID:26950371 NCBI chr 5:165,374,964...165,398,195
Ensembl chr 5:165,374,951...165,398,217
JBrowse link
G Gnl3l G protein nucleolar 3 like ISO (PMID:18082603) RGD PMID:18082603 NCBI chr  X:20,037,558...20,070,505
Ensembl chr  X:20,034,882...20,070,578
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 ISO
IEA
(PMID:23935072)
GO_REF:0000107
RGD
Ensembl
PMID:23935072 GO_REF:0000107 NCBI chr 7:144,865,302...144,871,592
Ensembl chr 7:144,865,608...144,871,585
JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C ISO (PMID:18082603) RGD PMID:18082603 NCBI chr15:28,486,605...28,517,353
Ensembl chr15:28,486,617...28,517,353
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U ISO
IBA
IEA
(PMID:18082603)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:18082603, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr13:96,222,093...96,238,845
Ensembl chr13:96,225,912...96,238,572
JBrowse link
G Nat10 N-acetyltransferase 10 ISO (PMID:18082603) RGD PMID:18082603 NCBI chr 3:93,658,119...93,698,136
Ensembl chr 3:93,658,117...93,698,136
JBrowse link
G Pif1 PIF1 5'-to-3' DNA helicase ISO (PMID:23657261) RGD PMID:23657261 NCBI chr 8:71,124,477...71,133,460
Ensembl chr 8:71,125,414...71,132,629
JBrowse link
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 ISO (PMID:11701125), (PMID:21119197) RGD PMID:11701125, PMID:21119197 NCBI chr15:47,211,682...47,270,343
Ensembl chr15:47,211,583...47,270,317
JBrowse link
G Pml PML nuclear body scaffold ISO (PMID:19567472) RGD PMID:19567472 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226
JBrowse link
G Pot1 protection of telomeres 1 ISO UniProtKB:Q96AP0 (PMID:15181449) RGD PMID:15181449 NCBI chr 4:51,888,632...51,946,764
Ensembl chr 4:51,888,634...51,946,715
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Stn1 STN1 subunit of CST complex IEA
ISO
GO_REF:0000107
(PMID:22763445)
Ensembl
RGD
PMID:22763445 GO_REF:0000107 NCBI chr 1:267,281,786...267,315,714
Ensembl chr 1:267,281,764...267,315,729
JBrowse link
G Ten1 TEN1 subunit of CST complex ISO
IBA
(PMID:22763445)
PMID:21873635
RGD PMID:22763445, PMID:21873635 RGD:13792537 NCBI chr10:105,073,077...105,095,094
Ensembl chr10:105,073,077...105,095,094
JBrowse link
G Tent4b terminal nucleotidyltransferase 4B ISO (PMID:26950371) RGD PMID:26950371 NCBI chr19:19,771,289...19,834,759
Ensembl chr19:19,771,677...19,832,812
JBrowse link
G Terf1 telomeric repeat binding factor 1 ISO UniProtKB:O14746 (PMID:11971978) RGD PMID:11971978 NCBI chr 5:2,853,455...2,882,731
Ensembl chr 5:2,853,459...2,882,668
JBrowse link
G Terf2 telomeric repeat binding factor 2 ISO (PMID:11971978), (PMID:17055345) RGD PMID:11971978, PMID:17055345 NCBI chr19:39,271,992...39,301,506
Ensembl chr19:39,272,499...39,300,893
JBrowse link
G Tinf2 TERF1 interacting nuclear factor 2 ISO (PMID:10581025), (PMID:15133513) RGD PMID:10581025, PMID:15133513 NCBI chr15:34,358,697...34,365,085
Ensembl chr15:34,360,974...34,364,081
JBrowse link
positive regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor ISO (PMID:17237768) RGD PMID:17237768 NCBI chr19:37,665,289...37,668,043
Ensembl chr19:37,665,296...37,667,987
JBrowse link
G Atm ATM serine/threonine kinase ISO (MGI:MGI:5705431|PMID:26586427) RGD PMID:26586427 MGI:MGI:5705431 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atr ATR serine/threonine kinase ISO (MGI:MGI:5705431|PMID:26586427) RGD PMID:26586427 MGI:MGI:5705431 NCBI chr 8:103,673,578...103,770,886
Ensembl chr 8:103,673,411...103,770,947
JBrowse link
G Aurkb aurora kinase B ISO (PMID:21531765) RGD PMID:21531765 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 7:60,106,532...60,122,779
Ensembl chr 7:60,109,974...60,122,805
JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 2:187,669,051...187,693,610
Ensembl chr 2:187,668,796...187,693,610
JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 ISO (PMID:25467444) RGD PMID:25467444 NCBI chr14:107,767,392...107,780,270
Ensembl chr14:107,767,392...107,780,270
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 2:84,667,578...84,678,730
Ensembl chr 2:84,667,633...84,678,790
JBrowse link
G Cct6a chaperonin containing TCP1 subunit 6A ISO (PMID:25467444) RGD PMID:25467444 NCBI chr12:30,491,584...30,501,813
Ensembl chr12:30,491,416...30,501,860
JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 4:117,235,023...117,252,265
Ensembl chr 4:117,235,023...117,252,265
JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 ISO (PMID:25467444) RGD PMID:25467444 NCBI chr11:27,130,172...27,141,881
Ensembl chr11:27,130,172...27,141,881
JBrowse link
G Ctnnb1 catenin beta 1 ISO
IEA
(MGI:MGI:5428344|PMID:22723415)
GO_REF:0000107
RGD
Ensembl
PMID:22723415 GO_REF:0000107, MGI:MGI:5428344 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 ISO MGI:MGI:3849598 (MGI:MGI:3047190|PMID:15240872) RGD PMID:15240872 MGI:MGI:3047190 NCBI chr  X:155,844,914...155,862,363
Ensembl chr  X:155,844,857...155,862,475
JBrowse link
G Fbxo4 F-box protein 4 ISO (PMID:16275645) RGD PMID:16275645 NCBI chr 2:53,797,954...53,811,134
Ensembl chr 2:53,797,954...53,811,134
JBrowse link
G Hmbox1 homeobox containing 1 ISO
IBA
(PMID:23685356)
PMID:21873635
RGD PMID:23685356, PMID:21873635 RGD:13792537 NCBI chr15:48,194,709...48,326,310
Ensembl chr15:48,199,995...48,284,548
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 ISO
IEA
(PMID:23935072)
GO_REF:0000107
RGD
Ensembl
PMID:23935072 GO_REF:0000107 NCBI chr 7:144,865,302...144,871,592
Ensembl chr 7:144,865,608...144,871,585
JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 ISO
IEA
(PMID:21531765)
GO_REF:0000107
RGD
Ensembl
PMID:21531765 GO_REF:0000107 NCBI chr12:2,546,278...2,555,310
Ensembl chr12:2,548,218...2,555,164
JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:48,625,714...48,711,642
Ensembl chr 1:48,625,743...48,711,642
JBrowse link
G Mapk1 mitogen activated protein kinase 1 ISO (PMID:21531765) RGD PMID:21531765 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk15 mitogen-activated protein kinase 15 ISO
IEA
(PMID:21531765)
GO_REF:0000107
RGD
Ensembl
PMID:21531765 GO_REF:0000107 NCBI chr 7:117,041,287...117,061,799
Ensembl chr 7:117,055,395...117,061,047
JBrowse link
G Mapk3 mitogen activated protein kinase 3 ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapkapk5 MAPK activated protein kinase 5 ISO (PMID:21531765) RGD PMID:21531765 NCBI chr12:40,510,378...40,529,332
Ensembl chr12:40,510,378...40,529,338
JBrowse link
G Nek2 NIMA-related kinase 2 ISO (PMID:21531765) RGD PMID:21531765 NCBI chr13:110,511,546...110,524,750
Ensembl chr13:110,511,668...110,522,769
JBrowse link
G Nek7 NIMA-related kinase 7 ISO
IEA
(PMID:21531765)
GO_REF:0000107
RGD
Ensembl
PMID:21531765 GO_REF:0000107 NCBI chr13:55,485,759...55,617,534
Ensembl chr13:55,488,531...55,561,750
JBrowse link
G Parn poly(A)-specific ribonuclease ISO (PMID:26482878), (PMID:26950371) RGD PMID:26482878, PMID:26950371 NCBI chr10:1,309,724...1,461,123
Ensembl chr10:1,308,414...1,461,269
JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta ISO
IEA
(PMID:21531765)
GO_REF:0000107
RGD
Ensembl
PMID:21531765 GO_REF:0000107 NCBI chr20:40,616,868...40,712,598
Ensembl chr20:40,618,128...40,712,592
JBrowse link
G Pnkp polynucleotide kinase 3'-phosphatase ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:100,853,475...100,859,202
Ensembl chr 1:100,853,902...100,859,084
JBrowse link
G Pot1 protection of telomeres 1 ISO (PMID:12768206), (PMID:12781132), (PMID:17237768) RGD PMID:12768206, PMID:12781132, PMID:17237768 NCBI chr 4:51,888,632...51,946,764
Ensembl chr 4:51,888,634...51,946,715
JBrowse link
G Prkcq protein kinase C, theta ISO
IEA
(PMID:21531765)
GO_REF:0000107
RGD
Ensembl
PMID:21531765 GO_REF:0000107 NCBI chr17:70,971,915...71,105,286
Ensembl chr17:70,971,915...71,105,286
JBrowse link
G Tcp1 t-complex 1 ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 1:48,025,664...48,033,343
Ensembl chr 1:48,025,663...48,033,396
JBrowse link
G Terc telomerase RNA component ISO MGI:MGI:1857930 (MGI:MGI:3774867|PMID:17982445) RGD PMID:17982445 MGI:MGI:3774867 NCBI chr 2:116,432,723...116,433,110
Ensembl chr 2:116,432,691...116,433,110
JBrowse link
G Tnks tankyrase ISO (PMID:11739745), (PMID:12782650), (PMID:18221737) RGD PMID:11739745, PMID:12782650, PMID:18221737 NCBI chr16:60,925,093...61,067,192
Ensembl chr16:60,925,093...61,067,192
JBrowse link
G Xrcc5 X-ray repair cross complementing 5 ISO (PMID:19188702) RGD PMID:19188702 NCBI chr 9:79,659,275...79,748,050
Ensembl chr 9:79,659,251...79,748,078
JBrowse link
regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase ISO UniProtKB:Q9NUX5 (PMID:26586433) RGD PMID:26586433 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Pot1 protection of telomeres 1 ISO
IBA
UniProtKB:Q13315 (PMID:26586433)
PMID:21873635
RGD PMID:26586433, PMID:21873635 RGD:13792537 NCBI chr 4:51,888,632...51,946,764
Ensembl chr 4:51,888,634...51,946,715
JBrowse link
G Pot1b protection of telomeres 1B IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:7,845,697...7,902,270
Ensembl chr 9:7,845,845...7,891,514
JBrowse link
G Terf2 telomeric repeat binding factor 2 ISO
IBA
(PMID:19864690), (PMID:23685356)
PMID:21873635
RGD PMID:19864690, PMID:23685356, PMID:21873635 RGD:13792537 NCBI chr19:39,271,992...39,301,506
Ensembl chr19:39,272,499...39,300,893
JBrowse link
telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkc1 dyskerin pseudouridine synthase 1 ISS
ISO
GO_REF:0000024
GO:0090669 (PMID:23685356), (PMID:26950371), (PMID:29695869)
UniProt
RGD
PMID:23685356, PMID:26950371, PMID:29695869 GO_REF:0000024 NCBI chr  X:155,844,914...155,862,363
Ensembl chr  X:155,844,857...155,862,475
JBrowse link
G Gar1 GAR1 ribonucleoprotein ISS
ISO
GO_REF:0000024
(PMID:29695869)
UniProt
RGD
PMID:29695869 GO_REF:0000024 NCBI chr 2:235,250,453...235,258,464
Ensembl chr 2:235,250,453...235,257,731
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 ISO (PMID:10197982) RGD PMID:10197982 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 ISO (PMID:10197982) RGD PMID:10197982 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
G Nhp2 NHP2 ribonucleoprotein ISO (PMID:29695869) RGD PMID:29695869 NCBI chr10:34,975,701...34,979,082
Ensembl chr10:34,975,708...34,979,082
JBrowse link
G Nop10 NOP10 ribonucleoprotein ISO (PMID:29695869) RGD PMID:29695869 NCBI chr 3:103,747,654...103,748,739
Ensembl chr 3:103,747,654...103,748,739
JBrowse link
G Parp4 poly (ADP-ribose) polymerase family, member 4 NOT ISO MGI:MGI:109573 (MGI:MGI:3045914|PMID:15169895) RGD PMID:15169895 MGI:MGI:3045914 NCBI chr15:36,809,362...36,911,167 JBrowse link
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 ISO (PMID:11701125) RGD PMID:11701125 NCBI chr15:47,211,682...47,270,343
Ensembl chr15:47,211,583...47,270,317
JBrowse link
G Pot1 protection of telomeres 1 ISO (PMID:12768206) RGD PMID:12768206 NCBI chr 4:51,888,632...51,946,764
Ensembl chr 4:51,888,634...51,946,715
JBrowse link
G Ptges3 prostaglandin E synthase 3 ISO
IBA
(MGI:MGI:5819359|PMID:10197982)
PMID:21873635
(PMID:10197982), (PMID:19740745)
RGD PMID:10197982, PMID:19740745, PMID:21873635 MGI:MGI:5819359, RGD:13792537 NCBI chr 7:2,479,267...2,497,024
Ensembl chr 7:2,479,311...2,497,013
JBrowse link
G Ptges3l1 prostaglandin E synthase 3-like 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:45,410,545...45,419,817
Ensembl chr  X:45,410,546...45,419,817
JBrowse link
G Rad50 RAD50 double strand break repair protein ISO
IBA
ISS
(PMID:9705271)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:9705271, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr10:39,002,130...39,054,042
Ensembl chr10:39,001,498...39,054,142
JBrowse link
G Rpa1 replication protein A1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:62,140,419...62,191,518
Ensembl chr10:62,140,419...62,191,512
JBrowse link
G Telo2 telomere maintenance 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:14,461,581...14,476,812
Ensembl chr10:14,461,839...14,476,785
JBrowse link
G Tep1 telomerase associated protein 1 NOT ISO MGI:MGI:2685589 (MGI:MGI:3045914|PMID:15169895) RGD PMID:15169895 MGI:MGI:3045914 NCBI chr15:27,751,186...27,798,839
Ensembl chr15:27,751,180...27,798,839
JBrowse link
G Terc telomerase RNA component TAS
ISO
MGI:MGI:1857930 (MGI:MGI:1097832|PMID:9335332) RGD PMID:9335332, PMID:10423530 MGI:MGI:1097832, RGD:1299555 NCBI chr 2:116,432,723...116,433,110
Ensembl chr 2:116,432,691...116,433,110
JBrowse link
G Terf1 telomeric repeat binding factor 1 ISO
IBA
(PMID:23685356), (PMID:9034193)
PMID:21873635
RGD PMID:9034193, PMID:23685356, PMID:21873635 RGD:13792537 NCBI chr 5:2,853,455...2,882,731
Ensembl chr 5:2,853,459...2,882,668
JBrowse link
G Tert telomerase reverse transcriptase ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:16043710), (PMID:17940095), (PMID:19701182), (PMID:21531765), (PMID:29695869), (PMID:9443919), (PMID:9454332)
UniProt
RGD
PMID:9443919, PMID:9454332, PMID:16043710, PMID:17940095, PMID:19701182, PMID:21531765, PMID:29695869, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 ISS
ISO
GO_REF:0000024
(PMID:23685356), (PMID:29695869), (PMID:29804836)
UniProt
RGD
PMID:23685356, PMID:29695869, PMID:29804836 GO_REF:0000024 NCBI chr10:56,169,024...56,185,800
Ensembl chr10:56,169,025...56,185,857
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      biosynthetic process 6225
        cellular biosynthetic process 6060
          cellular macromolecule biosynthetic process 5074
            DNA biosynthetic process 183
              RNA-dependent DNA biosynthetic process 65
                reverse transcription + 0
                telomere maintenance via telomerase + 65
Path 2
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      cellular metabolic process 11085
        heterocycle metabolic process 5640
          nucleobase-containing compound metabolic process 5489
            nucleic acid metabolic process 4985
              DNA metabolic process 923
                DNA biosynthetic process 183
                  RNA-dependent DNA biosynthetic process 65
                    reverse transcription + 0
                    telomere maintenance via telomerase + 65
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.