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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of DNA repair
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Accession:GO:0006282 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of DNA repair.


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regulation of DNA repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk9 cyclin dependent kinase 9 ISO (PMID:20493174) UniProtKB PMID:20493174 NCBI chrNW_004936487:15,446,864...15,450,750 JBrowse link
G Ier3 immediate early response 3 ISO (MGI:MGI:5432078|PMID:20467439) MGI PMID:20467439 MGI:MGI:5432078 NCBI chrNW_004936837:401,475...402,769 JBrowse link
G Sirt7 sirtuin 7 ISO (PMID:27436229), (PMID:30944854) UniProt PMID:27436229, PMID:30944854 NCBI chrNW_004936594:5,418,331...5,425,050 JBrowse link
G Suv39h1 suppressor of variegation 3-9 homolog 1 ISO (MGI:MGI:5913114|PMID:23695662) MGI PMID:23695662 MGI:MGI:5913114 NCBI chrNW_004936721:646,778...661,144 JBrowse link
G Usp1 ubiquitin specific peptidase 1 ISO (PMID:18082604) UniProtKB PMID:18082604 NCBI chrNW_004936692:147,699...159,921 JBrowse link
negative regulation of DNA repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rps3 ribosomal protein S3 ISO (PMID:17049931) UniProtKB PMID:17049931 NCBI chrNW_004936498:4,198,189...4,204,531 JBrowse link
negative regulation of double-strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Otub1 OTU deubiquitinase, ubiquitin aldehyde binding 1 ISO (PMID:20725033) UniProtKB PMID:20725033 NCBI chrNW_004936599:5,154,988...5,163,919 JBrowse link
G Rnf169 ring finger protein 169 ISO (PMID:22492721), (PMID:22733822)
(PMID:22742833)
UniProtKB PMID:22492721, PMID:22733822, PMID:22742833 NCBI chrNW_004936498:3,675,075...3,783,514 JBrowse link
G Trip12 thyroid hormone receptor interactor 12 ISO (PMID:22884692) UniProtKB PMID:22884692 NCBI chrNW_004936525:6,539,234...6,690,457 JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO (PMID:17690110) BHF-UCL PMID:17690110 NCBI chrNW_004936546:5,331,220...5,332,669 JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 ISO (PMID:22884692) UniProtKB PMID:22884692 NCBI chrNW_004936470:41,222,782...41,345,755 JBrowse link
negative regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cgas cyclic GMP-AMP synthase ISO (MGI:MGI:6241455|PMID:30356214)
(PMID:30356214)
UniProt PMID:30356214 MGI:MGI:6241455 NCBI chrNW_004936859:797,469...807,036 JBrowse link
G Fancb FA complementation group B ISO (MGI:MGI:5648586|PMID:25520194) MGI PMID:25520194 MGI:MGI:5648586 NCBI chrNW_004936470:4,305,220...4,323,456 JBrowse link
G Fbh1 F-box DNA helicase 1 ISO (PMID:19736316)
(MGI:MGI:5566975|PMID:24108124)
UniProtKB PMID:19736316, PMID:24108124 MGI:MGI:5566975 NCBI chrNW_004936484:8,635,752...8,689,949 JBrowse link
G Helb DNA helicase B ISO (PMID:26774285)
(MGI:MGI:5766842|PMID:26774285)
UniProtKB PMID:26774285 MGI:MGI:5766842 NCBI chrNW_004936545:4,318,256...4,346,438 JBrowse link
G Klhl15 kelch like family member 15 ISO (PMID:27561354) UniProtKB PMID:27561354 NCBI chrNW_004936624:552,220...593,546 JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 ISO (PMID:29656893) UniProtKB PMID:29656893 NCBI chrNW_004936474:538,703...542,901 JBrowse link
G Magef1 MAGE family member F1 ISO (PMID:29225034) UniProtKB PMID:29225034 NCBI chrNW_004936578:5,178,399...5,180,058 JBrowse link
G Parpbp PARP1 binding protein ISO (PMID:22153967) UniProtKB PMID:22153967 NCBI chrNW_004936492:11,948,765...11,994,838 JBrowse link
G Polq DNA polymerase theta ISO (PMID:25642963)
(MGI:MGI:5621198|PMID:25642960)
UniProtKB PMID:25642960, PMID:25642963 MGI:MGI:5621198 NCBI chrNW_004936536:7,904,166...8,004,305 JBrowse link
G Radx RPA1 related single stranded DNA binding protein, X-linked ISO (PMID:28735897) UniProtKB PMID:28735897 NCBI chrNW_004936499:8,058,973...8,122,332 JBrowse link
G Recql5 RecQ like helicase 5 ISO (MGI:MGI:5648586|PMID:25520194) MGI PMID:25520194 MGI:MGI:5648586 NCBI chrNW_004936594:829,296...862,615 JBrowse link
G Rif1 replication timing regulatory factor 1 ISO (PMID:23333306)
(MGI:MGI:5468037|PMID:23306437), (MGI:MGI:5476381|PMID:23333305)
UniProtKB PMID:23306437, PMID:23333305, PMID:23333306 MGI:MGI:5468037, MGI:MGI:5476381 NCBI chrNW_004936469:26,045,500...26,105,980 JBrowse link
G Shld1 shieldin complex subunit 1 ISO (PMID:29656893) UniProtKB PMID:29656893 NCBI chrNW_004936485:13,179,218...13,267,980 JBrowse link
G Shld2 shieldin complex subunit 2 ISO (PMID:29656893) UniProtKB PMID:29656893 NCBI chrNW_004936601:5,315,297...5,400,752 JBrowse link
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 ISO (PMID:25294876) UniProtKB PMID:25294876 NCBI chrNW_004936672:1,686,070...1,838,315 JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 ISO (MGI:MGI:5887194|PMID:20362325)
(PMID:23333306), (PMID:23345425)
(MGI:MGI:5476381|PMID:23333305)
UniProtKB PMID:20362325, PMID:23333305, PMID:23333306, PMID:23345425 MGI:MGI:5476381, MGI:MGI:5887194 NCBI chrNW_004936471:6,589,395...6,668,242 JBrowse link
G Ubqln4 ubiquilin 4 ISO (PMID:30612738) UniProt PMID:30612738 NCBI chrNW_004936580:5,299,864...5,316,583 JBrowse link
negative regulation of double-strand break repair via nonhomologous end joining term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aunip aurora kinase A and ninein interacting protein ISO (PMID:29042561) UniProtKB PMID:29042561 NCBI chrNW_004936474:10,409,463...10,430,158 JBrowse link
G Cyren cell cycle regulator of NHEJ ISO (PMID:28959974) UniProtKB PMID:28959974 NCBI chrNW_004936579:768,153...776,053 JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor ISO (PMID:25820262) UniProt PMID:25820262 NCBI chrNW_004936728:706,499...843,447 JBrowse link
G Hmga2 high mobility group AT-hook 2 ISO (PMID:19549901) UniProtKB PMID:19549901 NCBI chrNW_004936545:3,944,419...3,958,289 JBrowse link
G Hsf1 heat shock transcription factor 1 ISO (PMID:26359349) UniProtKB PMID:26359349 NCBI chrNW_004936470:7,927,734...7,950,805 JBrowse link
negative regulation of double-strand break repair via single-strand annealing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ogg1 8-oxoguanine DNA glycosylase ISO (PMID:19506022) MGI PMID:19506022 NCBI chrNW_004936602:3,411,106...3,418,826 JBrowse link
positive regulation of base-excision repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fam168a family with sequence similarity 168 member A ISO (PMID:25260657) UniProtKB PMID:25260657 NCBI chrNW_004936498:2,601,341...2,784,446 JBrowse link
G Rps3 ribosomal protein S3 ISO (PMID:18973764) UniProtKB PMID:18973764 NCBI chrNW_004936498:4,198,189...4,204,531 JBrowse link
positive regulation of DNA repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abraxas1 abraxas 1, BRCA1 A complex subunit ISO (PMID:17525340), (PMID:17643121), (PMID:19261748) UniProtKB PMID:17525340, PMID:17643121, PMID:19261748 NCBI chrNW_004936738:1,202,668...1,217,825 JBrowse link
G Apbb1 amyloid beta precursor protein binding family B member 1 ISO PMID:19282473
(MGI:MGI:3698695|PMID:17121854)
UniProt
UniProtKB
PMID:17121854, PMID:19282473 MGI:MGI:3698695, RGD:8553580 NCBI chrNW_004936842:452,682...476,533 JBrowse link
G Babam1 BRISC and BRCA1 A complex member 1 ISO (PMID:19261746), (PMID:19261748), (PMID:19261749) UniProtKB PMID:19261746, PMID:19261748, PMID:19261749 NCBI chrNW_004936596:3,574,507...3,582,370 JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 ISO (PMID:19261748) UniProtKB PMID:19261748 NCBI chrNW_004936493:4,375,393...4,863,050 JBrowse link
G Brca1 BRCA1 DNA repair associated ISO (PMID:17525340), (PMID:17643121), (PMID:19261748) UniProtKB PMID:17525340, PMID:17643121, PMID:19261748 NCBI chrNW_004936490:17,735,444...17,801,456 JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex subunit 3 ISO (PMID:17525341), (PMID:19261746), (PMID:19261748) UniProtKB PMID:17525341, PMID:19261746, PMID:19261748 NCBI chrNW_004936927:341,114...380,817 JBrowse link
G Cbx8 chromobox 8 ISO RGD PMID:23572236 RGD:9586727 NCBI chrNW_004936594:3,906,714...3,911,604 JBrowse link
G Cebpg CCAAT enhancer binding protein gamma ISO (PMID:16255782) UniProtKB PMID:16255782 NCBI chrNW_004936570:2,435,672...2,439,056 JBrowse link
G Dhx9 DExH-box helicase 9 ISO (PMID:24049074) UniProtKB PMID:24049074 NCBI chrNW_004936481:6,896,487...6,934,938 JBrowse link
G Egfr epidermal growth factor receptor ISO (PMID:17115032) UniProtKB PMID:17115032 NCBI chrNW_004936678:365,005...560,546 JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor ISO (PMID:22483866) UniProt PMID:22483866 NCBI chrNW_004936728:706,499...843,447 JBrowse link
G Ercc8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit ISO (PMID:7664335) UniProtKB PMID:7664335 NCBI chrNW_004936480:7,560,055...7,609,650 JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 ISO (PMID:19234442) UniProtKB PMID:19234442 NCBI chrNW_004936648:395,526...546,705 JBrowse link
G Eya3 EYA transcriptional coactivator and phosphatase 3 ISO (PMID:19234442) UniProtKB PMID:19234442 NCBI chrNW_004936474:12,191,391...12,295,380 JBrowse link
G Fgf10 fibroblast growth factor 10 ISO (PMID:14975937) UniProtKB PMID:14975937 NCBI chrNW_004936480:18,114,231...18,195,884 JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase ISO RGD PMID:1945835 RGD:729332 NCBI chrNW_004936486:16,744,607...16,923,209 JBrowse link
G Npas2 neuronal PAS domain protein 2 ISO (PMID:18819933) UniProtKB PMID:18819933 NCBI chrNW_004936661:96,312...176,395 JBrowse link
G Parg poly(ADP-ribose) glycohydrolase ISO RGD PMID:15158362 RGD:2316739 NCBI chrNW_004936728:428,028...538,413 JBrowse link
G Pcna proliferating cell nuclear antigen ISO (PMID:24939902) UniProtKB PMID:24939902 NCBI chrNW_004936485:13,766,221...13,771,215 JBrowse link
G Rnf168 ring finger protein 168 ISO (PMID:19203578), (PMID:19203579)
(PMID:23760478)
UniProtKB PMID:19203578, PMID:19203579, PMID:23760478 NCBI chrNW_004936784:1,073,236...1,094,575 JBrowse link
G Rnf8 ring finger protein 8 ISO (PMID:18001824), (PMID:18001825) UniProtKB PMID:18001824, PMID:18001825 NCBI chrNW_004936476:22,074,146...22,121,286 JBrowse link
G Rps3 ribosomal protein S3 ISO (PMID:23911537) UniProtKB PMID:23911537 NCBI chrNW_004936498:4,198,189...4,204,531 JBrowse link
G Sirt1 sirtuin 1 ISO (PMID:19934257) UniProtKB PMID:19934257 NCBI chrNW_004936521:10,296,097...10,316,673 JBrowse link
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 ISO (PMID:24790221) UniProtKB PMID:24790221 NCBI chrNW_004936672:1,686,070...1,838,315 JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase ISO (PMID:25928429) UniProtKB PMID:25928429 NCBI chrNW_004936606:4,518,525...4,540,109 JBrowse link
G Tmem161a transmembrane protein 161A ISO (PMID:16551573) BHF-UCL PMID:16551573 NCBI chrNW_004936596:2,274,989...2,287,288 JBrowse link
G Trim28 tripartite motif containing 28 ISO (PMID:17178852) UniProtKB PMID:17178852 NCBI chrNW_004937062:126,832...132,938 JBrowse link
G Ube2v2 ubiquitin conjugating enzyme E2 V2 ISO RGD PMID:12750002 RGD:1299567 NCBI chrNW_004936590:4,637,858...4,670,789 JBrowse link
G Uimc1 ubiquitin interaction motif containing 1 ISO (PMID:17525340), (PMID:17525341), (PMID:17525342), (PMID:17643121), (PMID:19261748) UniProtKB PMID:17525340, PMID:17525341, PMID:17525342, PMID:17643121, PMID:19261748 NCBI chrNW_004936597:1,143,835...1,260,339 JBrowse link
G Wrap53 WD repeat containing antisense to TP53 ISO (PMID:25512560) UniProtKB PMID:25512560 NCBI chrNW_004936595:936,184...952,784 JBrowse link
positive regulation of DNA repair by transcription from RNA polymerase II promoter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gtf2i general transcription factor IIi ISO (PMID:9334314) ARUK-UCL PMID:9334314 NCBI chrNW_004936543:3,521,763...3,611,410 JBrowse link
G Prrx1 paired related homeobox 1 ISO (PMID:9334314) ARUK-UCL PMID:9334314 NCBI chrNW_004936481:16,208,243...16,272,836 JBrowse link
positive regulation of double-strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx11 DEAD/H-box helicase 11 ISO (PMID:23797032) UniProtKB PMID:23797032 NCBI chrNW_004936606:181,457...209,286 JBrowse link
G Fmn2 formin 2 ISO (PMID:26287480) UniProt PMID:26287480 NCBI chrNW_004936526:9,832,790...10,169,488 JBrowse link
G Foxm1 forkhead box M1 ISO (MGI:MGI:3698692|PMID:17101782)
(PMID:17101782)
UniProtKB PMID:17101782 MGI:MGI:3698692 NCBI chrNW_004936606:3,185,289...3,198,427 JBrowse link
G LOC101965734 U8 snoRNA-decapping enzyme ISO (PMID:20385596) UniProtKB PMID:20385596 NCBI chrNW_004936529:4,825,277...4,827,011 JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase ISO (PMID:24147153) BHF-UCL PMID:24147153 NCBI chrNW_004936486:16,744,607...16,923,209 JBrowse link
G Slf1 SMC5-SMC6 complex localization factor 1 ISO (PMID:25931565) UniProtKB PMID:25931565 NCBI chrNW_004936523:8,563,662...8,634,576 JBrowse link
G Slf2 SMC5-SMC6 complex localization factor 2 ISO (PMID:25931565) UniProtKB PMID:25931565 NCBI chrNW_004936600:4,715,504...4,766,273 JBrowse link
G Spidr scaffold protein involved in DNA repair ISO (PMID:23509288) UniProtKB PMID:23509288 NCBI chrNW_004936590:4,921,755...5,041,573 JBrowse link
G Spire1 spire type actin nucleation factor 1 ISO (PMID:26287480) UniProt PMID:26287480 NCBI chrNW_004936626:2,151,990...2,292,307 JBrowse link
G Spire2 spire type actin nucleation factor 2 ISO (PMID:26287480) UniProt PMID:26287480 NCBI chrNW_004936641:236,135...246,004 JBrowse link
G Timeless timeless circadian regulator ISO (PMID:23797032) UniProtKB PMID:23797032 NCBI chrNW_004936646:780,021...792,856 JBrowse link
G Wrap53 WD repeat containing antisense to TP53 ISO (PMID:27715493) UniProtKB PMID:27715493 NCBI chrNW_004936595:936,184...952,784 JBrowse link
G Zcwpw1 zinc finger CW-type and PWWP domain containing 1 ISO (MGI:MGI:6358520|PMID:31453335) ARUK-UCL PMID:31453335 MGI:MGI:6358520 NCBI chrNW_004936543:482,795...503,996 JBrowse link
positive regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr2 actin related protein 2 ISO (PMID:29925947) UniProt PMID:29925947 NCBI chrNW_004936491:9,980,228...10,021,417 JBrowse link
G Arid2 AT-rich interaction domain 2 ISO (PMID:28381560) CACAO PMID:28381560 NCBI chrNW_004936512:4,020,303...4,199,390 JBrowse link
G Blm BLM RecQ like helicase ISO (MGI:MGI:5648586|PMID:25520194) MGI PMID:25520194 MGI:MGI:5648586 NCBI chrNW_004936483:16,194,092...16,295,803 JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor ISO (PMID:25820262) UniProt PMID:25820262 NCBI chrNW_004936728:706,499...843,447 JBrowse link
G Fancb FA complementation group B ISO (MGI:MGI:5648586|PMID:25520194) MGI PMID:25520194 MGI:MGI:5648586 NCBI chrNW_004936470:4,305,220...4,323,456 JBrowse link
G Fus FUS RNA binding protein ISO (PMID:10567410) UniProt PMID:10567410 NCBI chrNW_004936501:13,529,732...13,541,102 JBrowse link
G Mms19 MMS19 homolog, cytosolic iron-sulfur assembly component ISO (PMID:29225034) UniProtKB PMID:29225034 NCBI chrNW_004936636:2,191,748...2,221,027 JBrowse link
G Mrnip MRN complex interacting protein ISO (PMID:27568553) UniProtKB PMID:27568553 NCBI chrNW_004936739:926,678...955,024 JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 ISO (PMID:26344098), (PMID:30356214) UniProt PMID:26344098, PMID:30356214 NCBI chrNW_004936526:3,102,468...3,147,601 JBrowse link
G Timeless timeless circadian regulator ISO (PMID:26344098), (PMID:30356214) UniProt PMID:26344098, PMID:30356214 NCBI chrNW_004936646:780,021...792,856 JBrowse link
G Was WASP actin nucleation promoting factor ISO (PMID:29925947) UniProt PMID:29925947 NCBI chrNW_004936721:634,685...641,248 JBrowse link
G Wrap53 WD repeat containing antisense to TP53 ISO (PMID:25512560) UniProtKB PMID:25512560 NCBI chrNW_004936595:936,184...952,784 JBrowse link
positive regulation of double-strand break repair via nonhomologous end joining term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dtx3l deltex E3 ubiquitin ligase 3L ISO (PMID:28525742) UniProtKB PMID:28525742 NCBI chrNW_004936536:8,844,778...8,853,442 JBrowse link
G Fh fumarate hydratase ISO (PMID:26237645) UniProt PMID:26237645 NCBI chrNW_004936526:8,936,096...8,965,155 JBrowse link
G Kdm4d lysine demethylase 4D ISO (PMID:24550317) MGI PMID:24550317 NCBI chrNW_004936674:53,200...73,042 JBrowse link
G Kmt5b lysine methyltransferase 5B ISO (PMID:28114273) UniProt PMID:28114273 NCBI chrNW_004936599:1,928,172...1,983,983 JBrowse link
G Kmt5c lysine methyltransferase 5C ISO (PMID:28114273) UniProt PMID:28114273 NCBI chrNW_004936886:596,949...602,959 JBrowse link
G LOC101962206 histone-lysine N-methyltransferase SETMAR ISO (PMID:20620605), (PMID:21491884) UniProtKB PMID:20620605, PMID:21491884 NCBI chrNW_004936577:3,761,078...3,771,864 JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 ISO (PMID:29656893) UniProtKB PMID:29656893 NCBI chrNW_004936474:538,703...542,901 JBrowse link
G Parp3 poly(ADP-ribose) polymerase family member 3 ISO (PMID:24598253) UniProt PMID:24598253 NCBI chrNW_004936529:3,291,282...3,297,581 JBrowse link
G Parp9 poly(ADP-ribose) polymerase family member 9 ISO (PMID:28525742) UniProtKB PMID:28525742 NCBI chrNW_004936536:8,806,824...8,845,099 JBrowse link
G Pnkp polynucleotide kinase 3'-phosphatase ISO (PMID:12032095) CACAO PMID:12032095 NCBI chrNW_004936664:3,649,020...3,656,545 JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit ISO (PMID:26237645) UniProt PMID:26237645 NCBI chrNW_004936590:4,722,914...4,887,615 JBrowse link
G Rif1 replication timing regulatory factor 1 ISO (MGI:MGI:5468037|PMID:23306437), (MGI:MGI:5476381|PMID:23333305)
(PMID:28241136)
UniProtKB PMID:23306437, PMID:23333305, PMID:28241136 MGI:MGI:5468037, MGI:MGI:5476381 NCBI chrNW_004936469:26,045,500...26,105,980 JBrowse link
G Shld1 shieldin complex subunit 1 ISO (PMID:29656893) UniProtKB PMID:29656893 NCBI chrNW_004936485:13,179,218...13,267,980 JBrowse link
G Shld2 shieldin complex subunit 2 ISO (PMID:29656893), (PMID:29789392) UniProtKB PMID:29656893, PMID:29789392 NCBI chrNW_004936601:5,315,297...5,400,752 JBrowse link
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 ISO (PMID:25294876) UniProtKB PMID:25294876 NCBI chrNW_004936672:1,686,070...1,838,315 JBrowse link
G Top2b DNA topoisomerase II beta ISO RGD PMID:22019940 RGD:13432143 NCBI chrNW_004936473:17,146,576...17,189,589 JBrowse link
G Wrap53 WD repeat containing antisense to TP53 ISO (PMID:25512560) UniProtKB PMID:25512560 NCBI chrNW_004936595:936,184...952,784 JBrowse link
positive regulation of mismatch repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac10 histone deacetylase 10 ISO (PMID:26221039) UniProt PMID:26221039 NCBI chrNW_004936629:562,038...567,709 JBrowse link
G Hmgb1 high mobility group box 1 ISO (PMID:15014079) UniProtKB PMID:15014079 NCBI chrNW_004936472:25,236,728...25,246,585 JBrowse link
G Prkcg protein kinase C gamma ISO (PMID:15808853) HGNC PMID:15808853 NCBI chrNW_004936994:87,525...105,125 JBrowse link
positive regulation of single strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp1 poly(ADP-ribose) polymerase 1 ISO (PMID:28002403)
(MGI:MGI:5902647|PMID:28002403)
UniProtKB PMID:28002403 MGI:MGI:5902647 NCBI chrNW_004936526:3,102,468...3,147,601 JBrowse link
G Xrcc1 X-ray repair cross complementing 1 ISO (PMID:28002403)
(MGI:MGI:5902647|PMID:28002403)
UniProtKB PMID:28002403 MGI:MGI:5902647 NCBI chrNW_004936706:752,571...783,746 JBrowse link
regulation of DNA double-strand break processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Helb DNA helicase B ISO (PMID:26774285)
(MGI:MGI:5766842|PMID:26774285)
UniProtKB PMID:26774285 MGI:MGI:5766842 NCBI chrNW_004936545:4,318,256...4,346,438 JBrowse link
regulation of double-strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dek DEK proto-oncogene ISO (PMID:21653549) MGI PMID:21653549 NCBI chrNW_004936552:3,964,515...3,997,318 JBrowse link
G Pml PML nuclear body scaffold ISO (PMID:21639834) UniProtKB PMID:21639834 NCBI chrNW_004936471:33,135,186...33,173,218 JBrowse link
regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chek1 checkpoint kinase 1 ISO (PMID:15665856) UniProtKB PMID:15665856 NCBI chrNW_004936743:2,004,535...2,027,287 JBrowse link
G Fignl1 fidgetin like 1 ISO (PMID:23754376) UniProtKB PMID:23754376 NCBI chrNW_004936686:1,412,544...1,415,939 JBrowse link
G Kdm1a lysine demethylase 1A ISO (PMID:24217620) MGI PMID:24217620 NCBI chrNW_004936474:8,262,913...8,319,089 JBrowse link
G Ppp4c protein phosphatase 4 catalytic subunit ISO (PMID:20154705) UniProtKB PMID:20154705 NCBI chrNW_004936501:12,407,968...12,416,057 JBrowse link
G Ppp4r2 protein phosphatase 4 regulatory subunit 2 ISO (PMID:20154705) UniProtKB PMID:20154705 NCBI chrNW_004936603:3,994,594...4,041,972 JBrowse link
G Rad51 RAD51 recombinase ISO (PMID:23754376) UniProtKB PMID:23754376 NCBI chrNW_004936471:4,119,020...4,136,811 JBrowse link
G Rad51ap1 RAD51 associated protein 1 ISO (PMID:23754376) UniProtKB PMID:23754376 NCBI chrNW_004936606:4,697,369...4,716,006 JBrowse link
G Rpa2 replication protein A2 ISO (PMID:20154705) UniProtKB PMID:20154705 NCBI chrNW_004936474:12,127,026...12,147,120 JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 ISO (PMID:18957201) UniProtKB PMID:18957201 NCBI chrNW_004936514:10,920,979...10,954,483 JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase ISO (PMID:24843002) UniProtKB PMID:24843002 NCBI chrNW_004936596:795,940...898,823 JBrowse link
G Sirt6 sirtuin 6 ISO (PMID:19135889) UniProtKB PMID:19135889 NCBI chrNW_004936588:2,387,162...2,394,066 JBrowse link
G Spidr scaffold protein involved in DNA repair ISO (PMID:23754376) UniProtKB PMID:23754376 NCBI chrNW_004936590:4,921,755...5,041,573 JBrowse link
G Terf2ip TERF2 interacting protein ISO (MGI:MGI:4440768|PMID:20339076) UniProtKB PMID:20339076 MGI:MGI:4440768 NCBI chrNW_004936475:24,312,140...24,319,492 JBrowse link
G Tex15 testis expressed 15, meiosis and synapsis associated ISO (MGI:MGI:3794139|PMID:18283110) MGI PMID:18283110 MGI:MGI:3794139 NCBI chrNW_004936792:668,290...727,197 JBrowse link
G Usp51 ubiquitin specific peptidase 51 ISO (PMID:27083998) UniProtKB PMID:27083998 NCBI chrNW_004936819:1,115,524...1,119,083 JBrowse link
G Znf365 zinc finger protein 365 ISO (PMID:23966166) UniProtKB PMID:23966166 NCBI chrNW_004936614:833,665...853,547 JBrowse link
regulation of double-strand break repair via nonhomologous end joining term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr2 actin related protein 2 NOT ISO (PMID:29925947) UniProt PMID:29925947 NCBI chrNW_004936491:9,980,228...10,021,417 JBrowse link
G Dek DEK proto-oncogene ISO (MGI:MGI:5317387|PMID:21653549) MGI PMID:21653549 MGI:MGI:5317387 NCBI chrNW_004936552:3,964,515...3,997,318 JBrowse link
G Mrnip MRN complex interacting protein ISO (PMID:27568553) UniProtKB PMID:27568553 NCBI chrNW_004936739:926,678...955,024 JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 ISO (MGI:MGI:5462481|PMID:23241889) MGI PMID:23241889 MGI:MGI:5462481 NCBI chrNW_004936477:21,460,442...21,531,563 JBrowse link
G Pot1 protection of telomeres 1 ISO (PMID:29227966) CACAO PMID:29227966 NCBI chrNW_004936605:836,824...919,099 JBrowse link
G Sirt7 sirtuin 7 ISO (MGI:MGI:5789069|PMID:27225932) UniProt PMID:27225932 MGI:MGI:5789069 NCBI chrNW_004936594:5,418,331...5,425,050 JBrowse link
G Usp51 ubiquitin specific peptidase 51 ISO (PMID:27083998) UniProtKB PMID:27083998 NCBI chrNW_004936819:1,115,524...1,119,083 JBrowse link
G Was WASP actin nucleation promoting factor NOT ISO (PMID:29925947) UniProt PMID:29925947 NCBI chrNW_004936721:634,685...641,248 JBrowse link
regulation of mismatch repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axin2 axin 2 ISO (PMID:11017067) BHF-UCL PMID:11017067 NCBI chrNW_004936541:7,155,963...7,242,466 JBrowse link
regulation of nucleotide-excision repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cul4a cullin 4A ISO (MGI:MGI:3850765|PMID:19481525) MGI PMID:19481525 MGI:MGI:3850765 NCBI chrNW_004936472:409,083...432,442 JBrowse link
G Hmgb1 high mobility group box 1 ISO (MGI:MGI:3807115|PMID:18650382) UniProt PMID:18650382 MGI:MGI:3807115 NCBI chrNW_004936472:25,236,728...25,246,585 JBrowse link
G Kat7 lysine acetyltransferase 7 ISO (PMID:28719581) UniProt PMID:28719581 NCBI chrNW_004936490:11,775,224...11,805,489 JBrowse link
G Rad52 RAD52 homolog, DNA repair protein ISO (PMID:19506022) MGI PMID:19506022 NCBI chrNW_004936606:1,070,336...1,099,684 JBrowse link
regulation of single strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp1 poly(ADP-ribose) polymerase 1 ISO (MGI:MGI:5616996|PMID:25378300) MGI PMID:25378300 MGI:MGI:5616996 NCBI chrNW_004936526:3,102,468...3,147,601 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11968
    cellular process 11136
      regulation of cellular process 7896
        regulation of cellular response to stress 679
          regulation of response to DNA damage stimulus 212
            regulation of DNA repair 121
              negative regulation of DNA repair + 29
              positive regulation of DNA repair + 72
              regulation of base-excision repair + 2
              regulation of double-strand break repair + 80
              regulation of error-prone translesion synthesis + 0
              regulation of mismatch repair + 4
              regulation of nucleotide-excision repair + 4
              regulation of single strand break repair + 2
Path 2
Term Annotations click to browse term
  biological_process 11968
    metabolic process 7653
      cellular metabolic process 7051
        cellular aromatic compound metabolic process 3743
          nucleobase-containing compound metabolic process 3574
            nucleic acid metabolic process 3288
              DNA metabolic process 655
                DNA repair 335
                  regulation of DNA repair 121
                    negative regulation of DNA repair + 29
                    positive regulation of DNA repair + 72
                    regulation of base-excision repair + 2
                    regulation of double-strand break repair + 80
                    regulation of error-prone translesion synthesis + 0
                    regulation of mismatch repair + 4
                    regulation of nucleotide-excision repair + 4
                    regulation of single strand break repair + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.