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ONTOLOGY REPORT - ANNOTATIONS


Term:base-excision repair, AP site formation
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Accession:GO:0006285 term browser browse the term
Definition:The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recognizes an altered base in DNA and catalyzes its hydrolytic removal. This sugar phosphate is the substrate recognized by the AP endonuclease, which cuts the DNA phosphodiester backbone at the 5' side of the altered site to leave a gap which is subsequently repaired.


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base-excision repair, AP site formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nthl1 nth-like DNA glycosylase 1 JBrowse link 10 13,996,660 14,002,827 RGD:1624291
RGD:13792537
G Ogg1 8-oxoguanine DNA glycosylase JBrowse link 4 145,282,828 145,289,367 RGD:13792537
G Tdg thymine-DNA glycosylase JBrowse link 7 27,194,000 27,213,676 RGD:1624291
RGD:13792537
base-excision repair, AP site formation via deaminated base removal term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ung uracil-DNA glycosylase JBrowse link 12 48,246,593 48,255,547 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12096
      cellular metabolic process 10917
        cellular macromolecule metabolic process 8392
          DNA metabolic process 911
            base-excision repair, AP site formation 4
              base-excision repair, AP site formation via deaminated base removal 1
              depurination 0
              depyrimidination 0
Path 2
Term Annotations click to browse term
  biological_process 19858
    cellular process 18617
      cellular metabolic process 10917
        cellular nitrogen compound metabolic process 6542
          nucleobase-containing compound metabolic process 5344
            nucleic acid metabolic process 4850
              DNA metabolic process 911
                DNA repair 477
                  base-excision repair 45
                    base-excision repair, AP site formation 4
                      base-excision repair, AP site formation via deaminated base removal 1
                      depurination 0
                      depyrimidination 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.