Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:DNA catabolic process
go back to main search page
Accession:GO:0006308 term browser browse the term
Definition:The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.
Synonyms:exact_synonym: DNA breakdown;   DNA catabolism;   DNA degradation


show annotations for term's descendants       view all columns           Sort by:
 
DNA catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dffb DNA fragmentation factor subunit beta JBrowse link 5 171,250,559 171,261,875 RGD:1624291
G Dnase1 deoxyribonuclease 1 JBrowse link 10 11,757,681 11,760,672 RGD:13792537
G Dnase1l1 deoxyribonuclease 1-like 1 JBrowse link X 156,429,521 156,438,066 RGD:1600115
RGD:13792537
G Dnase1l2 deoxyribonuclease 1 like 2 JBrowse link 10 13,812,335 13,814,514 RGD:1624291
RGD:13792537
G Dnase1l3 deoxyribonuclease 1-like 3 JBrowse link 15 18,710,492 18,736,476 RGD:13792537
G Trex1 three prime repair exonuclease 1 JBrowse link 8 117,796,127 117,797,427 RGD:1624291
apoptotic DNA fragmentation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dffa DNA fragmentation factor subunit alpha JBrowse link 5 165,922,893 165,935,822 RGD:1600115
G Dffb DNA fragmentation factor subunit beta JBrowse link 5 171,250,559 171,261,875 RGD:628524
RGD:1600115
RGD:13792537
RGD:1624291
G Dicer1 dicer 1 ribonuclease III JBrowse link 6 128,388,084 128,453,234 RGD:13792537
G Dnase1l3 deoxyribonuclease 1-like 3 JBrowse link 15 18,710,492 18,736,476 RGD:728743
RGD:13792537
RGD:1624291
G Dnase2 deoxyribonuclease 2, lysosomal JBrowse link 19 26,022,855 26,025,523 RGD:13792537
G Dnase2b deoxyribonuclease 2 beta JBrowse link 2 252,436,363 252,475,506 RGD:13792537
G Endog endonuclease G JBrowse link 3 8,741,833 8,744,414 RGD:1624291
RGD:13792537
G Exog exo/endonuclease G JBrowse link 8 128,133,398 128,153,110 RGD:13792537
G Foxl2 forkhead box L2 JBrowse link 8 107,194,492 107,197,644 RGD:1624291
DNA catabolic process, endonucleolytic term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dnase1 deoxyribonuclease 1 JBrowse link 10 11,757,681 11,760,672 RGD:1624291
RGD:13792537
RGD:13464261
G Dnase1l1 deoxyribonuclease 1-like 1 JBrowse link X 156,429,521 156,438,066 RGD:13792537
G Dnase1l2 deoxyribonuclease 1 like 2 JBrowse link 10 13,812,335 13,814,514 RGD:13792537
G Dnase1l3 deoxyribonuclease 1-like 3 JBrowse link 15 18,710,492 18,736,476 RGD:1624291
RGD:13792537
RGD:13464261
G Endog endonuclease G JBrowse link 3 8,741,833 8,744,414 RGD:13792537
G Exog exo/endonuclease G JBrowse link 8 128,133,398 128,153,110 RGD:13792537
G Fbh1 F-box DNA helicase 1 JBrowse link 17 70,399,093 70,437,151 RGD:1624291
G Mus81 MUS81 structure-specific endonuclease subunit JBrowse link 1 220,862,474 220,867,973 RGD:1624291
G Rexo4 REX4 homolog, 3'-5' exonuclease JBrowse link 3 5,500,578 5,510,908 RGD:1624291
RGD:13792537
G Setmar SET domain and mariner transposase fusion gene JBrowse link 4 140,092,346 140,104,495 RGD:1624291
G Spo11 SPO11, initiator of meiotic double stranded breaks JBrowse link 3 170,991,573 171,008,226 RGD:1600115
DNA catabolic process, exonucleolytic term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eri1 exoribonuclease 1 JBrowse link 16 60,307,148 60,327,237 RGD:13792537
G Eri2 ERI1 exoribonuclease family member 2 JBrowse link 1 189,540,145 189,549,891 RGD:13792537
G Eri3 ERI1 exoribonuclease family member 3 JBrowse link 5 136,406,009 136,533,408 RGD:13792537
G Isg20 interferon stimulated exonuclease gene 20 JBrowse link 1 140,602,553 140,608,892 RGD:1624291
RGD:13792537
G Rexo4 REX4 homolog, 3'-5' exonuclease JBrowse link 3 5,500,578 5,510,908 RGD:1624291
RGD:13792537
G Xrn2 5'-3' exoribonuclease 2 JBrowse link 3 141,224,858 141,298,272 RGD:1624291
negative regulation of apoptotic DNA fragmentation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dffa DNA fragmentation factor subunit alpha JBrowse link 5 165,922,893 165,935,822 RGD:1624291
G Nmnat1 nicotinamide nucleotide adenylyltransferase 1 JBrowse link 5 166,409,460 166,430,291 RGD:13781945
G Pam16 presequence translocase associated motor 16 JBrowse link 10 11,146,359 11,153,936 RGD:13462066
negative regulation of DNA catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rgn regucalcin JBrowse link X 1,833,484 1,848,904 RGD:9590215
positive regulation of apoptotic DNA fragmentation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1624291
RGD:1600115
G Endog endonuclease G JBrowse link 3 8,741,833 8,744,414 RGD:9685355
G Hsf1 heat shock transcription factor 1 JBrowse link 7 117,538,523 117,565,478 RGD:10403035
G Igfbp3 insulin-like growth factor binding protein 3 JBrowse link 14 87,457,647 87,465,374 RGD:10402776
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
positive regulation of DNA catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:12879393
regulation of apoptotic DNA fragmentation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aifm1 apoptosis inducing factor, mitochondria associated 1 JBrowse link X 135,304,063 135,343,062 RGD:1624291
G Apaf1 apoptotic peptidase activating factor 1 JBrowse link 7 31,699,309 31,784,192 RGD:1624291
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:1624291
G Cidea cell death-inducing DFFA-like effector a JBrowse link 18 63,082,861 63,108,450 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12096
      cellular metabolic process 10917
        cellular macromolecule metabolic process 8392
          DNA metabolic process 911
            DNA catabolic process 35
              DNA catabolic process, endonucleolytic + 27
              DNA catabolic process, exonucleolytic 6
              mitochondrial DNA catabolic process 0
              negative regulation of DNA catabolic process + 4
              positive regulation of DNA catabolic process + 6
              regulation of DNA catabolic process + 14
Path 2
Term Annotations click to browse term
  biological_process 19858
    cellular process 18617
      cellular metabolic process 10917
        cellular aromatic compound metabolic process 5567
          nucleobase-containing compound metabolic process 5344
            nucleic acid metabolic process 4850
              DNA metabolic process 911
                DNA catabolic process 35
                  DNA catabolic process, endonucleolytic + 27
                  DNA catabolic process, exonucleolytic 6
                  mitochondrial DNA catabolic process 0
                  negative regulation of DNA catabolic process + 4
                  positive regulation of DNA catabolic process + 6
                  regulation of DNA catabolic process + 14
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.