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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA methylation-dependent heterochromatin assembly
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Accession:GO:0006346 term browser browse the term
Definition:Repression of transcription by methylation of DNA, leading to the formation of heterochromatin.
Synonyms:exact_synonym: methylation-dependent heterochromatic silencing
 broad_synonym: methylation-dependent chromatin silencing


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DNA methylation-dependent heterochromatin assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dnmt3a DNA methyltransferase 3 alpha JBrowse link 6 28,205,375 28,346,052 RGD:1624291
G Dnmt3b DNA methyltransferase 3 beta JBrowse link 3 149,131,541 149,170,061 RGD:1624291
G Hdac1 histone deacetylase 1 JBrowse link 5 147,716,664 147,743,723 RGD:1624291
G Hells helicase, lymphoid specific JBrowse link 1 257,901,856 257,953,889 RGD:1624291
RGD:13792537
G LOC100911660 lymphocyte-specific helicase-like JBrowse link 1 257,614,688 257,660,184 RGD:13792537
G Mbd2 methyl-CpG binding domain protein 2 JBrowse link 18 65,814,026 65,885,115 RGD:1624291
G Mbd3 methyl-CpG binding domain protein 3 JBrowse link 7 12,179,046 12,186,251 RGD:1624291
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 JBrowse link 8 22,648,323 22,739,468 RGD:1624291
negative regulation of DNA methylation-dependent heterochromatin assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aicda activation-induced cytidine deaminase JBrowse link 4 155,359,909 155,371,104 RGD:1624291
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 JBrowse link 4 155,386,367 155,414,034 RGD:1624291
RGD:1600115
G Tet1 tet methylcytosine dioxygenase 1 JBrowse link 20 27,359,122 27,438,039 RGD:1624291
positive regulation of DNA methylation-dependent heterochromatin assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atf7ip activating transcription factor 7 interacting protein JBrowse link 4 170,476,998 170,563,063 RGD:1624291
G Dnmt1 DNA methyltransferase 1 JBrowse link 8 21,922,515 21,968,495 RGD:1600115
RGD:1624291
G Morc2 MORC family CW-type zinc finger 2 JBrowse link 14 83,889,138 83,930,263 RGD:1624291
G Mphosph8 M-phase phosphoprotein 8 JBrowse link 15 36,918,843 36,946,712 RGD:1600115
RGD:1624291
G Pphln1 periphilin 1 JBrowse link 7 134,602,109 134,693,807 RGD:1624291
G Resf1 retroelement silencing factor 1 JBrowse link 4 183,879,177 183,905,807 RGD:1624291
G Setdb1 SET domain bifurcated histone lysine methyltransferase 1 JBrowse link 2 196,495,867 196,527,412 RGD:1624291
RGD:13792537
G Setdb2 SET domain bifurcated histone lysine methyltransferase 2 JBrowse link 15 38,699,135 39,745,035 RGD:13792537
G Tasor transcription activation suppressor JBrowse link 16 3,050,506 3,108,168 RGD:1624291
G Trim28 tripartite motif-containing 28 JBrowse link 1 65,544,369 65,551,043 RGD:1624291
RGD:1600115
regulation of DNA methylation-dependent heterochromatin assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pou5f1 POU class 5 homeobox 1 JBrowse link 20 3,747,231 3,751,994 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    cellular process 18617
      cellular component organization or biogenesis 6706
        cellular component organization 6456
          chromatin organization 834
            covalent chromatin modification 507
              DNA methylation-dependent heterochromatin assembly 22
                negative regulation of DNA methylation-dependent heterochromatin assembly 3
                positive regulation of DNA methylation-dependent heterochromatin assembly 10
                regulation of DNA methylation-dependent heterochromatin assembly + 14
Path 2
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12096
      cellular metabolic process 10917
        cellular aromatic compound metabolic process 5567
          nucleobase-containing compound metabolic process 5344
            nucleic acid metabolic process 4850
              RNA metabolic process 4347
                regulation of RNA metabolic process 3510
                  negative regulation of RNA metabolic process 1418
                    negative regulation of RNA biosynthetic process 1316
                      negative regulation of nucleic acid-templated transcription 1314
                        negative regulation of transcription, DNA-templated 1280
                          chromatin organization involved in negative regulation of transcription 130
                            heterochromatin assembly 52
                              DNA methylation-dependent heterochromatin assembly 22
                                negative regulation of DNA methylation-dependent heterochromatin assembly 3
                                positive regulation of DNA methylation-dependent heterochromatin assembly 10
                                regulation of DNA methylation-dependent heterochromatin assembly + 14
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.