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ONTOLOGY REPORT - ANNOTATIONS


Term:transcription elongation from RNA polymerase II promoter
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Accession:GO:0006368 term browser browse the term
Definition:The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.
Synonyms:exact_synonym: RNA elongation from Pol II promoter
 related_synonym: RNA polymerase II transcription elongation factor activity


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transcription elongation from RNA polymerase II promoter term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07002622.1 IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 1:77,721,411...77,721,737 JBrowse link
G AABR07051791.1 IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 3:21,521,165...21,521,912 JBrowse link
G AABR07051982.1 IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 3:30,929,848...30,930,141 JBrowse link
G AABR07060156.1 IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 4:60,054,287...60,054,622 JBrowse link
G AABR07068955.1 IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 8:3,271,956...3,272,306 JBrowse link
G AC119015.2 IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr10:76,280,933...76,281,283 JBrowse link
G AC119015.3 IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr10:76,274,563...76,274,859 JBrowse link
G AC132539.1 IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 8:119,285,668...119,286,024 JBrowse link
G Adrm1 adhesion regulating molecule 1 ISO (PMID:11818576) RGD PMID:11818576 NCBI chr 3:175,548,181...175,552,943
Ensembl chr 3:175,548,174...175,552,947
JBrowse link
G Cdc73 cell division cycle 73 ISO
IEA
ISS
(PMID:20178742)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
GO_Central
PMID:20178742 GO_REF:0000024, GO_REF:0000107 NCBI chr13:60,403,771...60,496,511
Ensembl chr13:60,403,771...60,496,511
JBrowse link
G Cdk12 cyclin-dependent kinase 12 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:86,157,186...86,210,657
Ensembl chr10:86,157,608...86,222,707
JBrowse link
G Cdk13 cyclin-dependent kinase 13 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:49,833,194...49,922,932
Ensembl chr17:49,833,400...49,921,550
JBrowse link
G Ctr9 CTR9 homolog, Paf1/RNA polymerase II complex component ISO (PMID:20178742) RGD PMID:20178742 NCBI chr 1:175,839,140...175,869,167
Ensembl chr 1:175,839,108...175,869,165
JBrowse link
G Ell elongation factor for RNA polymerase II IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr16:20,594,129...20,641,441
Ensembl chr16:20,594,072...20,641,908
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:2,456,189...2,525,590
Ensembl chr 2:2,456,735...2,524,237
JBrowse link
G Ell3 elongation factor for RNA polymerase II 3 ISO (PMID:10882741) RGD PMID:10882741 NCBI chr 3:113,400,395...113,405,869
Ensembl chr 3:113,401,734...113,405,829
JBrowse link
G Eloa elongin A IDA
IEA
PMID:8896449
GO_REF:0000002
InterPro PMID:8896449 GO_REF:0000002, RGD:8553414 NCBI chr 5:154,348,167...154,363,324
Ensembl chr 5:154,347,391...154,363,329
JBrowse link
G Elob elongin B IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:13,163,032...13,168,217
Ensembl chr10:13,163,036...13,168,217
JBrowse link
G Elof1 elongation factor 1 homolog IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:23,125,987...23,130,980
Ensembl chr 8:23,125,988...23,130,877
JBrowse link
G Eny2 ENY2, transcription and export complex 2 subunit IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 7:83,348,656...83,358,430
Ensembl chr 7:83,348,694...83,357,492
JBrowse link
G Gtf2f1 general transcription factor IIF subunit 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:10,032,806...10,042,392
Ensembl chr 9:10,033,011...10,042,418
JBrowse link
G Gtf2f2 general transcription factor IIF subunit 2 IDA RGD PMID:7929273 RGD:9681417 NCBI chr15:57,942,057...58,068,892
Ensembl chr15:57,942,059...58,068,892
JBrowse link
G Leo1 LEO1 homolog, Paf1/RNA polymerase II complex component ISO
ISS
(PMID:20178742)
GO_REF:0000024
RGD
GO_Central
PMID:20178742 GO_REF:0000024 NCBI chr 8:82,380,906...82,405,293
Ensembl chr 8:82,380,757...82,405,644
JBrowse link
G LOC100909963 transcription elongation factor B polypeptide 2-like IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:3,271,922...3,272,881 JBrowse link
G LOC103691042 transcription elongation factor B polypeptide 2 pseudogene IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:77,721,405...77,721,857 JBrowse link
G LOC103691783 transcription elongation factor B polypeptide 2 pseudogene IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:30,929,770...30,930,137 JBrowse link
G LOC689396 similar to RNA polymerase II elongation factor ELL2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:151,745,424...151,754,977
Ensembl chr  X:151,745,455...151,754,964
JBrowse link
G Paf1 PAF1 homolog, Paf1/RNA polymerase II complex component ISO
ISS
(PMID:20178742)
GO_REF:0000024
RGD
GO_Central
PMID:20178742 GO_REF:0000024 NCBI chr 1:85,362,421...85,367,999
Ensembl chr 1:85,362,268...85,368,031
JBrowse link
G Pcid2 PCI domain containing 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:81,757,582...81,783,047
Ensembl chr16:81,756,971...81,783,047
JBrowse link
G RGD1304870 similar to Tceb2 protein IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:76,278,747...76,281,411 JBrowse link
G RGD1561118 similar to transcription elongation factor B (SIII), polypeptide 2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:76,274,440...76,284,458 JBrowse link
G RGD1563055 similar to transcription elongation factor B (SIII), polypeptide 2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:60,054,126...60,054,622 JBrowse link
G RGD1563330 similar to elongin B isoform b IEA GO_REF:0000002 InterPro GO_REF:0000002
G Rtf1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) ISO (PMID:20178742) RGD PMID:20178742 NCBI chr 3:111,478,350...111,537,941
Ensembl chr 3:111,478,382...111,537,941
JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase ISO (PMID:23325844) RGD PMID:23325844 NCBI chr 8:118,802,478...118,888,224
Ensembl chr 8:118,803,075...118,888,224
JBrowse link
G Sox10 SRY-box transcription factor 10 IDA RGD PMID:25524031 RGD:12879827 NCBI chr 7:120,393,238...120,403,523
Ensembl chr 7:120,393,254...120,403,523
JBrowse link
G Supt16h SPT16 homolog, facilitates chromatin remodeling subunit IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:28,574,841...28,611,959
Ensembl chr15:28,575,480...28,611,946
JBrowse link
G Supt4h1 SPT4 homolog, DSIF elongation factor subunit ISO (PMID:9450929), (PMID:9857195) RGD PMID:9450929, PMID:9857195 NCBI chr10:75,032,365...75,038,547
Ensembl chr10:75,032,365...75,038,547
JBrowse link
G Supt5h SPT5 homolog, DSIF elongation factor subunit ISO
IBA
(PMID:10075709), (PMID:9450929)
PMID:21873635
RGD PMID:9450929, PMID:10075709, PMID:21873635 RGD:13792537 NCBI chr 1:85,437,780...85,466,854
Ensembl chr 1:85,437,780...85,466,854
JBrowse link
G Supt6h SPT6 homolog, histone chaperone and transcription elongation factor IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:65,470,470...65,507,581
Ensembl chr10:65,470,471...65,507,581
JBrowse link
G Wdr61 WD repeat domain 61 ISO
ISS
(PMID:20178742)
GO_REF:0000024
RGD
GO_Central
PMID:20178742 GO_REF:0000024 NCBI chr 8:59,296,339...59,313,663
Ensembl chr 8:59,296,346...59,313,574
JBrowse link
maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103690054 DNA-directed RNA polymerase II subunit RPB9 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:91,041,173...91,042,258
Ensembl chr 1:91,041,214...91,042,230
Ensembl chr 1:91,041,214...91,042,230
JBrowse link
G Polr2i RNA polymerase II subunit I IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:88,686,812...88,688,249
Ensembl chr 1:88,686,731...88,688,258
JBrowse link
negative regulation of transcription elongation from RNA polymerase II promoter term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axin1 axin 1 ISO (MGI:MGI:1336856|PMID:10318824), (MGI:MGI:3840033|PMID:19204372) RGD PMID:10318824, PMID:19204372 MGI:MGI:1336856, MGI:MGI:3840033
G Eapp E2F-associated phosphoprotein ISO (PMID:15716352) RGD PMID:15716352 NCBI chr 6:75,561,898...75,589,274
Ensembl chr 6:75,567,511...75,589,257
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO MGI:MGI:2661097 (MGI:MGI:3846264|PMID:19303854) RGD PMID:19303854 MGI:MGI:3846264 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U IEA
ISO
GO_REF:0000107
(PMID:10490622)
Ensembl
RGD
PMID:10490622 GO_REF:0000107 NCBI chr13:96,222,093...96,238,845
Ensembl chr13:96,225,912...96,238,572
JBrowse link
G Nelfa negative elongation factor complex member A ISO
IBA
(MGI:MGI:5014448|PMID:21670248)
PMID:21873635
RGD PMID:21670248, PMID:21873635 MGI:MGI:5014448, RGD:13792537 NCBI chr14:82,093,837...82,117,913
Ensembl chr14:82,093,837...82,117,906
JBrowse link
G Nelfb negative elongation factor complex member B IBA
ISO
PMID:21873635
(MGI:MGI:3845453|PMID:19340312), (MGI:MGI:5576446|PMID:24656816), (MGI:MGI:6270977|PMID:25773599)
RGD PMID:19340312, PMID:24656816, PMID:25773599, PMID:21873635 MGI:MGI:3845453, MGI:MGI:5576446, MGI:MGI:6270977, RGD:13792537 NCBI chr 3:2,414,448...2,431,148
Ensembl chr 3:2,414,451...2,431,148
JBrowse link
G Nelfcd negative elongation factor complex member C/D IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:172,510,840...172,527,118
Ensembl chr 3:172,510,874...172,526,740
JBrowse link
G Nelfe negative elongation factor complex member E ISO
IBA
(MGI:MGI:5014448|PMID:21670248)
PMID:21873635
RGD PMID:21670248, PMID:21873635 MGI:MGI:5014448, RGD:13792537 NCBI chr20:4,530,328...4,536,085
Ensembl chr20:4,530,342...4,536,209
JBrowse link
G Recql5 RecQ like helicase 5 ISO
ISS
(PMID:23748380)
GO_REF:0000024
RGD
UniProt
PMID:23748380 GO_REF:0000024 NCBI chr10:104,443,735...104,482,889
Ensembl chr10:104,443,736...104,482,838
JBrowse link
G Rnf168 ring finger protein 168 ISO
IEA
ISS
(PMID:20550933)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:20550933 GO_REF:0000024, GO_REF:0000107 NCBI chr11:71,721,242...71,743,421
Ensembl chr11:71,721,250...71,743,421
JBrowse link
G Rnf8 ring finger protein 8 ISO
ISS
(PMID:20550933)
GO_REF:0000024
RGD
UniProt
PMID:20550933 GO_REF:0000024 NCBI chr20:8,285,380...8,309,858
Ensembl chr20:8,285,296...8,309,908
JBrowse link
G Shh sonic hedgehog signaling molecule ISO
IEA
(MGI:MGI:3703195|PMID:17284610)
GO_REF:0000107
RGD
Ensembl
PMID:17284610 GO_REF:0000107, MGI:MGI:3703195 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691
JBrowse link
G Supt4h1 SPT4 homolog, DSIF elongation factor subunit ISO (MGI:MGI:5014448|PMID:21670248) RGD PMID:21670248 MGI:MGI:5014448 NCBI chr10:75,032,365...75,038,547
Ensembl chr10:75,032,365...75,038,547
JBrowse link
positive regulation of transcription elongation from RNA polymerase II promoter term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07035541.3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr12:19,254,189...19,254,527 JBrowse link
G AABR07044940.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr20:27,352,276...27,352,684 JBrowse link
G Brd4 bromodomain containing 4 ISO (PMID:18039861), (PMID:19103749), (PMID:23086925) RGD PMID:18039861, PMID:19103749, PMID:23086925 NCBI chr 7:14,222,101...14,303,055
Ensembl chr 7:14,222,101...14,303,055
JBrowse link
G Btbd18 BTB domain containing 18 ISO
IBA
(MGI:MGI:5882241|PMID:28292424)
PMID:21873635
RGD PMID:28292424, PMID:21873635 MGI:MGI:5882241, RGD:13792537 NCBI chr 3:72,060,811...72,070,566
Ensembl chr 3:72,063,504...72,069,534
JBrowse link
G Cbx7 chromobox 7 IMP RGD PMID:19706751 RGD:9586729 NCBI chr 7:121,136,067...121,153,503
Ensembl chr 7:121,136,058...121,153,383
JBrowse link
G Cdc73 cell division cycle 73 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:60,403,771...60,496,511
Ensembl chr13:60,403,771...60,496,511
JBrowse link
G Cdk12 cyclin-dependent kinase 12 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:86,157,186...86,210,657
Ensembl chr10:86,157,608...86,222,707
JBrowse link
G Cdk13 cyclin-dependent kinase 13 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:49,833,194...49,922,932
Ensembl chr17:49,833,400...49,921,550
JBrowse link
G Ctnnb1 catenin beta 1 ISO
IEA
MGI:MGI:2148567|MGI:MGI:3841145 (MGI:MGI:6284231|PMID:30478225)
GO_REF:0000107
RGD
Ensembl
PMID:30478225 GO_REF:0000107, MGI:MGI:6284231 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Dab2 DAB adaptor protein 2 ISO (MGI:MGI:5442512|PMID:15894542) RGD PMID:15894542 MGI:MGI:5442512 NCBI chr 2:55,747,353...55,768,848
Ensembl chr 2:55,747,318...55,768,270
JBrowse link
G Eapp E2F-associated phosphoprotein ISO (PMID:15716352) RGD PMID:15716352 NCBI chr 6:75,561,898...75,589,274
Ensembl chr 6:75,567,511...75,589,257
JBrowse link
G Ell elongation factor for RNA polymerase II ISO (PMID:23932780) RGD PMID:23932780 NCBI chr16:20,594,129...20,641,441
Ensembl chr16:20,594,072...20,641,908
JBrowse link
G Eloc elongin C IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:8202474, PMID:21873635 RGD:730008, RGD:13792537 NCBI chr 5:2,042,991...2,059,357
Ensembl chr 5:2,042,991...2,059,351
JBrowse link
G Gtf2f1 general transcription factor IIF subunit 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:10,032,806...10,042,392
Ensembl chr 9:10,033,011...10,042,418
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 ISO MGI:MGI:2158690 (MGI:MGI:5317044|PMID:21245044) RGD PMID:21245044 MGI:MGI:5317044 NCBI chr14:91,782,281...91,867,828
Ensembl chr14:91,782,354...91,867,424
JBrowse link
G Leo1 LEO1 homolog, Paf1/RNA polymerase II complex component IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:82,380,906...82,405,293
Ensembl chr 8:82,380,757...82,405,644
JBrowse link
G LOC103691088 transcription elongation factor B polypeptide 1 pseudogene IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:19,254,160...19,254,590 JBrowse link
G LOC103694416 transcription elongation factor B polypeptide 1 pseudogene IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:27,352,167...27,352,667 JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 IMP RGD PMID:18086894 RGD:2292639 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Supt16h SPT16 homolog, facilitates chromatin remodeling subunit IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:28,574,841...28,611,959
Ensembl chr15:28,575,480...28,611,946
JBrowse link
G Supt6h SPT6 homolog, histone chaperone and transcription elongation factor ISO
IBA
(PMID:17234882)
PMID:21873635
(MGI:MGI:5508611|PMID:17234882)
RGD PMID:17234882, PMID:21873635 MGI:MGI:5508611, RGD:13792537 NCBI chr10:65,470,470...65,507,581
Ensembl chr10:65,470,471...65,507,581
JBrowse link
regulation of transcription elongation from RNA polymerase II promoter term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eaf1 ELL associated factor 1 ISO (PMID:32087315) RGD PMID:32087315 NCBI chr16:7,588,217...7,602,966
Ensembl chr16:7,588,217...7,602,966
JBrowse link
G Eaf2 ELL associated factor 2 ISO (PMID:32087315) RGD PMID:32087315 NCBI chr11:66,878,658...66,923,092
Ensembl chr11:66,878,658...66,923,092
JBrowse link
G Ldb1 LIM domain binding 1 ISO (MGI:MGI:4834059|PMID:20570862) RGD PMID:20570862 MGI:MGI:4834059 NCBI chr 1:265,772,729...265,798,442
Ensembl chr 1:265,785,409...265,798,167
JBrowse link
G Supt4h1 SPT4 homolog, DSIF elongation factor subunit IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:75,032,365...75,038,547
Ensembl chr10:75,032,365...75,038,547
JBrowse link
G Wdr43 WD repeat domain 43 ISO (MGI:MGI:6323527|PMID:31128943) RGD PMID:31128943 MGI:MGI:6323527 NCBI chr 6:23,433,532...23,473,179
Ensembl chr 6:23,433,532...23,473,169
JBrowse link
G Zmynd11 zinc finger, MYND-type containing 11 ISO (MGI:MGI:5560379|PMID:24590075) RGD PMID:24590075 MGI:MGI:5560379 NCBI chr17:63,825,616...63,914,740
Ensembl chr17:63,825,627...63,879,171
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      organic substance metabolic process 11651
        macromolecule metabolic process 10086
          gene expression 6304
            transcription, DNA-templated 3418
              DNA-templated transcription, elongation 94
                transcription elongation from RNA polymerase II promoter 72
                  maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter 2
                  negative regulation of transcription elongation from RNA polymerase II promoter 13
                  positive regulation of transcription elongation from RNA polymerase II promoter + 21
                  regulation of transcription elongation from RNA polymerase II promoter + 38
Path 2
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      cellular metabolic process 11085
        cellular aromatic compound metabolic process 5715
          nucleobase-containing compound metabolic process 5489
            nucleic acid metabolic process 4985
              RNA metabolic process 4469
                RNA biosynthetic process 3477
                  nucleic acid-templated transcription 3463
                    transcription, DNA-templated 3418
                      DNA-templated transcription, elongation 94
                        transcription elongation from RNA polymerase II promoter 72
                          maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter 2
                          negative regulation of transcription elongation from RNA polymerase II promoter 13
                          positive regulation of transcription elongation from RNA polymerase II promoter + 21
                          regulation of transcription elongation from RNA polymerase II promoter + 38
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.