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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular protein modification process
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Accession:GO:0006464 term browser browse the term
Definition:The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
Synonyms:broad_synonym: protein modification process
 related_synonym: process resulting in protein modification;   protein tagging activity
 xref: MIPS_funcat:14;   MIPS_funcat:14.07;   MIPS_funcat:18.01.01


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Path 1
Term Annotations click to browse term
  biological_process 19245
    metabolic process 11438
      cellular metabolic process 10461
        cellular macromolecule metabolic process 8037
          cellular protein metabolic process 5268
            cellular protein modification process 3844
              ISG15-protein conjugation 5
              N-terminal protein amino acid modification + 29
              actin modification + 5
              attachment of GPI anchor to protein 5
              charged-tRNA amino acid modification + 1
              co-translational protein modification + 2
              enzyme active site formation + 2
              formation of oxidatively modified proteins involved in replicative cell aging 0
              histone modification + 484
              metal incorporation into metallo-molybdopterin complex + 1
              metal incorporation into metallo-oxygen cluster + 0
              metal incorporation into metallo-sulfur cluster + 2
              negative regulation of protein modification process + 618
              nucleic acid-protein covalent cross-linking + 0
              peptide cross-linking + 34
              peptidyl-amino acid modification + 1270
              positive regulation of protein modification process + 1286
              post-translational protein modification + 25
              protein ADP-ribosylation + 37
              protein acylation + 263
              protein alkylation + 198
              protein amidation + 1
              protein arginylation 2
              protein biotinylation + 1
              protein carbamoylation + 0
              protein carboxylation + 4
              protein de-ADP-ribosylation + 6
              protein deacylation + 111
              protein dealkylation + 32
              protein deamination + 0
              protein deglutathionylation 0
              protein deglycation + 2
              protein deglycosylation + 13
              protein dehydration + 0
              protein delipidation 1
              protein denucleotidylation + 1
              protein dephosphorylation + 310
              protein desulfurization 0
              protein esterification + 0
              protein flavinylation 0
              protein glucuronidation + 1
              protein glutathionylation + 2
              protein glycosylation + 217
              protein halogenation + 0
              protein hydroxylation + 29
              protein initiator methionine removal + 3
              protein lipidation + 94
              protein modification by small protein conjugation or removal + 899
              protein nitrosylation + 14
              protein nucleotidylation + 2
              protein oxidation + 15
              protein phosphopantetheinylation + 0
              protein phosphorylation + 1953
              protein polyamination + 0
              protein prenylation + 11
              protein sialylation 5
              protein sulfation + 6
              protein sulfhydration + 1
              protein tyrosinylation + 1
              protein-chromophore linkage + 10
              protein-cofactor linkage + 9
              protein-tetrapyrrole linkage + 1
              regulation of protein modification process + 1917
              sulfur incorporation into metallo-sulfur cluster 0
              trans-translation-dependent protein tagging 0
Path 2
Term Annotations click to browse term
  biological_process 19245
    metabolic process 11438
      organic substance metabolic process 10836
        macromolecule metabolic process 9317
          protein metabolic process 5943
            protein modification process 3844
              cellular protein modification process 3844
                ISG15-protein conjugation 5
                N-terminal protein amino acid modification + 29
                actin modification + 5
                attachment of GPI anchor to protein 5
                charged-tRNA amino acid modification + 1
                co-translational protein modification + 2
                enzyme active site formation + 2
                formation of oxidatively modified proteins involved in replicative cell aging 0
                histone modification + 484
                metal incorporation into metallo-molybdopterin complex + 1
                metal incorporation into metallo-oxygen cluster + 0
                metal incorporation into metallo-sulfur cluster + 2
                negative regulation of protein modification process + 618
                nucleic acid-protein covalent cross-linking + 0
                peptide cross-linking + 34
                peptidyl-amino acid modification + 1270
                positive regulation of protein modification process + 1286
                post-translational protein modification + 25
                protein ADP-ribosylation + 37
                protein acylation + 263
                protein alkylation + 198
                protein amidation + 1
                protein arginylation 2
                protein biotinylation + 1
                protein carbamoylation + 0
                protein carboxylation + 4
                protein de-ADP-ribosylation + 6
                protein deacylation + 111
                protein dealkylation + 32
                protein deamination + 0
                protein deglutathionylation 0
                protein deglycation + 2
                protein deglycosylation + 13
                protein dehydration + 0
                protein delipidation 1
                protein denucleotidylation + 1
                protein dephosphorylation + 310
                protein desulfurization 0
                protein esterification + 0
                protein flavinylation 0
                protein glucuronidation + 1
                protein glutathionylation + 2
                protein glycosylation + 217
                protein halogenation + 0
                protein hydroxylation + 29
                protein initiator methionine removal + 3
                protein lipidation + 94
                protein modification by small protein conjugation or removal + 899
                protein nitrosylation + 14
                protein nucleotidylation + 2
                protein oxidation + 15
                protein phosphopantetheinylation + 0
                protein phosphorylation + 1953
                protein polyamination + 0
                protein prenylation + 11
                protein sialylation 5
                protein sulfation + 6
                protein sulfhydration + 1
                protein tyrosinylation + 1
                protein-chromophore linkage + 10
                protein-cofactor linkage + 9
                protein-tetrapyrrole linkage + 1
                regulation of protein modification process + 1917
                sulfur incorporation into metallo-sulfur cluster 0
                trans-translation-dependent protein tagging 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.