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ONTOLOGY REPORT - ANNOTATIONS


Term:signal peptide processing
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Accession:GO:0006465 term browser browse the term
Definition:The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell.
Synonyms:exact_synonym: leader peptide processing


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signal peptide processing term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arxes2 adipocyte-related X-chromosome expressed sequence 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:106,522,900...106,524,832
Ensembl chr  X:106,523,278...106,523,820
Ensembl chr  X:106,523,278...106,523,820
JBrowse link
G Cln5 CLN5, intracellular trafficking protein ISO (PMID:20052765) RGD PMID:20052765 NCBI chr15:93,634,815...93,644,146 JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) ISO
IEA
(PMID:16912035)
GO_REF:0000107
RGD
Ensembl
PMID:16912035 GO_REF:0000107 NCBI chr 1:142,185,092...142,198,167
Ensembl chr 1:142,185,094...142,197,182
JBrowse link
G Hm13 histocompatibility minor 13 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:148,150,695...148,189,623
Ensembl chr 3:148,150,698...148,189,623
JBrowse link
G MGC109340 similar to Microsomal signal peptidase 23 kDa subunit (SPase 22 kDa subunit) (SPC22/23) IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:106,487,872...106,489,391
Ensembl chr  X:106,487,870...106,489,387
JBrowse link
G Pcsk5 proprotein convertase subtilisin/kexin type 5 ISO (PMID:16912035) RGD PMID:16912035 NCBI chr 1:236,031,988...236,313,858
Ensembl chr 1:236,031,988...236,313,858
JBrowse link
G Sec11a SEC11 homolog A, signal peptidase complex subunit IEA
IBA
GO_REF:0000104
PMID:21873635
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 1:142,733,423...142,759,999
Ensembl chr 1:142,733,434...142,759,882
JBrowse link
G Sec11c SEC11 homolog C, signal peptidase complex subunit IEA
IBA
GO_REF:0000104
PMID:21873635
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr18:61,490,051...61,506,393
Ensembl chr18:61,490,031...61,506,508
JBrowse link
G Spcs1 signal peptidase complex subunit 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:7,080,389...7,081,957
Ensembl chr16:7,080,454...7,082,193
JBrowse link
G Spcs2 signal peptidase complex subunit 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:164,829,896...164,849,749
Ensembl chr 1:164,829,896...164,849,749
JBrowse link
G Spcs3 signal peptidase complex subunit 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:40,050,862...40,056,296
Ensembl chr16:40,050,734...40,058,822
JBrowse link
G Sppl3 signal peptide peptidase like 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:47,276,485...47,360,552
Ensembl chr12:47,276,476...47,360,507
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    metabolic process 12256
      primary metabolic process 10901
        protein metabolic process 6214
          cellular protein metabolic process 5552
            signal peptide processing 12
              SRP-dependent cotranslational protein targeting to membrane, signal sequence processing 0
Path 2
Term Annotations click to browse term
  biological_process 20017
    metabolic process 12256
      organic substance metabolic process 11636
        macromolecule metabolic process 10081
          gene expression 6295
            protein maturation 303
              protein processing 237
                signal peptide processing 12
                  SRP-dependent cotranslational protein targeting to membrane, signal sequence processing 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.