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ONTOLOGY REPORT - ANNOTATIONS


Term:GPI anchor biosynthetic process
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Accession:GO:0006506 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
Synonyms:exact_synonym: GPI anchor anabolism;   GPI anchor biosynthesis;   GPI anchor formation;   GPI anchor synthesis;   glycosylphosphatidylinositol biosynthesis;   glycosylphosphatidylinositol biosynthetic process
 broad_synonym: GPI/GSI anchor biosynthesis;   GPI/GSI anchor biosynthetic process
 alt_id: GO:0015998


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GPI anchor biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pigz phosphatidylinositol glycan anchor biosynthesis class Z JBrowse link NW_004936833 902,002 918,321 RGD:9068941
preassembly of GPI anchor in ER membrane term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pigz phosphatidylinositol glycan anchor biosynthesis class Z JBrowse link NW_004936833 902,002 918,321 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 327
    metabolic process 216
      biosynthetic process 123
        organic substance biosynthetic process 121
          carbohydrate derivative biosynthetic process 12
            glycolipid biosynthetic process 1
              GPI anchor biosynthetic process 1
                GPI anchor biosynthetic process via N-alanyl-glycosylphosphatidylinositolethanolamine 0
                GPI anchor biosynthetic process via N-asparaginyl-glycosylphosphatidylinositolethanolamine 0
                GPI anchor biosynthetic process via N-aspartyl-glycosylphosphatidylinositolethanolamine 0
                GPI anchor biosynthetic process via N-cysteinyl-glycosylphosphatidylinositolethanolamine 0
                GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine 0
                GPI anchor biosynthetic process via N-seryl-glycosylphosphatidylinositolethanolamine 0
                GPI anchor biosynthetic process via N-threonyl-glycosylphosphatidylinositolethanolamine 0
                attachment of GPI anchor to protein 0
                preassembly of GPI anchor in ER membrane 1
Path 2
Term Annotations click to browse term
  biological_process 327
    metabolic process 216
      cellular metabolic process 205
        phosphorus metabolic process 59
          phosphate-containing compound metabolic process 59
            phospholipid metabolic process 10
              glycerophospholipid metabolic process 7
                phosphatidylinositol metabolic process 5
                  GPI anchor metabolic process 1
                    GPI anchor biosynthetic process 1
                      GPI anchor biosynthetic process via N-alanyl-glycosylphosphatidylinositolethanolamine 0
                      GPI anchor biosynthetic process via N-asparaginyl-glycosylphosphatidylinositolethanolamine 0
                      GPI anchor biosynthetic process via N-aspartyl-glycosylphosphatidylinositolethanolamine 0
                      GPI anchor biosynthetic process via N-cysteinyl-glycosylphosphatidylinositolethanolamine 0
                      GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine 0
                      GPI anchor biosynthetic process via N-seryl-glycosylphosphatidylinositolethanolamine 0
                      GPI anchor biosynthetic process via N-threonyl-glycosylphosphatidylinositolethanolamine 0
                      attachment of GPI anchor to protein 0
                      preassembly of GPI anchor in ER membrane 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.