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ONTOLOGY REPORT - ANNOTATIONS


Term:proline metabolic process
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Accession:GO:0006560 term browser browse the term
Definition:The chemical reactions and pathways involving proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.
Synonyms:exact_synonym: proline metabolism


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arginine catabolic process to proline via ornithine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Oat ornithine aminotransferase JBrowse link 1 204,562,289 204,582,070 RGD:13792537
L-proline biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 JBrowse link 1 259,641,673 259,674,521 RGD:1600115
G LOC108348083 delta-1-pyrroline-5-carboxylate synthase JBrowse link 1 259,057,407 259,089,727 RGD:1600115
G Noxred1 NADP-dependent oxidoreductase domain containing 1 JBrowse link 6 111,243,232 111,271,107 RGD:13792537
G Oat ornithine aminotransferase JBrowse link 1 204,562,289 204,582,070 RGD:1600115
G Pycr1 pyrroline-5-carboxylate reductase 1 JBrowse link 10 109,817,300 109,822,218 RGD:1600115
RGD:13792537
G Pycr2 pyrroline-5-carboxylate reductase 2 JBrowse link 13 99,184,624 99,188,418 RGD:1600115
RGD:13792537
G Pycr3 pyrroline-5-carboxylate reductase 3 JBrowse link 7 116,949,882 116,955,150 RGD:1600115
RGD:13792537
RGD:1624291
proline biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 JBrowse link 1 259,641,673 259,674,521 RGD:1624291
G Pycr1 pyrroline-5-carboxylate reductase 1 JBrowse link 10 109,817,300 109,822,218 RGD:1624291
G Pycr2 pyrroline-5-carboxylate reductase 2 JBrowse link 13 99,184,624 99,188,418 RGD:1624291
RGD:1600115
proline catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dao D-amino-acid oxidase JBrowse link 12 48,353,691 48,373,647 RGD:1600115
RGD:13792537
RGD:1624291
G Prodh2 proline dehydrogenase 2 JBrowse link 1 88,955,125 88,968,501 RGD:1600115
proline catabolic process to glutamate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 JBrowse link 5 158,090,238 158,115,725 RGD:1600115
G Iffo2 intermediate filament family orphan 2 JBrowse link 5 158,042,587 158,083,311 RGD:1600115
G Prodh1 proline dehydrogenase 1 JBrowse link 11 87,058,478 87,075,785 RGD:13792537
G Prodh2 proline dehydrogenase 2 JBrowse link 1 88,955,125 88,968,501 RGD:13792537
G Tas1r2 taste 1 receptor member 2 JBrowse link 5 158,119,894 158,135,733 RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19678
    cellular process 18452
      cellular metabolic process 10782
        heterocycle metabolic process 5463
          proline metabolic process 13
            arginine catabolic process to proline + 1
            negative regulation of proline metabolic process + 0
            nopaline catabolic process to proline 0
            octopine catabolic process to proline 0
            ornithine catabolic process via proline 0
            positive regulation of proline metabolic process + 0
            proline biosynthetic process + 7
            proline catabolic process + 6
            regulation of proline metabolic process + 0
Path 2
Term Annotations click to browse term
  biological_process 19678
    metabolic process 11954
      cellular metabolic process 10782
        organic acid metabolic process 1068
          oxoacid metabolic process 1041
            carboxylic acid metabolic process 993
              cellular amino acid metabolic process 272
                alpha-amino acid metabolic process 197
                  glutamine family amino acid metabolic process 74
                    proline metabolic process 13
                      arginine catabolic process to proline + 1
                      negative regulation of proline metabolic process + 0
                      nopaline catabolic process to proline 0
                      octopine catabolic process to proline 0
                      ornithine catabolic process via proline 0
                      positive regulation of proline metabolic process + 0
                      proline biosynthetic process + 7
                      proline catabolic process + 6
                      regulation of proline metabolic process + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.