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ONTOLOGY REPORT - ANNOTATIONS


Term:proline biosynthetic process
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Accession:GO:0006561 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.
Synonyms:exact_synonym: proline anabolism;   proline biosynthesis;   proline formation;   proline synthesis
 xref: MetaCyc:PROSYN-PWY;   MetaCyc:PWY-3341


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proline biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 JBrowse link 1 259,641,673 259,674,521 RGD:1624291
G Pycr1 pyrroline-5-carboxylate reductase 1 JBrowse link 10 109,817,300 109,822,218 RGD:1624291
G Pycr2 pyrroline-5-carboxylate reductase 2 JBrowse link 13 99,184,624 99,188,418 RGD:1624291
RGD:1600115
L-proline biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 JBrowse link 1 259,641,673 259,674,521 RGD:1600115
G LOC108348083 delta-1-pyrroline-5-carboxylate synthase JBrowse link 1 259,057,407 259,089,727 RGD:1600115
G Noxred1 NADP-dependent oxidoreductase domain containing 1 JBrowse link 6 111,243,232 111,271,107 RGD:13792537
G Oat ornithine aminotransferase JBrowse link 1 204,562,289 204,582,070 RGD:1600115
G Pycr1 pyrroline-5-carboxylate reductase 1 JBrowse link 10 109,817,300 109,822,218 RGD:1600115
RGD:13792537
G Pycr2 pyrroline-5-carboxylate reductase 2 JBrowse link 13 99,184,624 99,188,418 RGD:1600115
RGD:13792537
G Pycr3 pyrroline-5-carboxylate reductase 3 JBrowse link 7 116,949,882 116,955,150 RGD:1600115
RGD:13792537
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12096
      organic substance metabolic process 11494
        organic cyclic compound metabolic process 5784
          organic cyclic compound biosynthetic process 3982
            proline biosynthetic process 7
              L-proline biosynthetic process 7
              negative regulation of proline biosynthetic process 0
              proline salvage 0
              regulation of proline biosynthetic process + 0
Path 2
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12096
      cellular metabolic process 10917
        organic acid metabolic process 1073
          oxoacid metabolic process 1046
            carboxylic acid metabolic process 998
              cellular amino acid metabolic process 273
                alpha-amino acid metabolic process 198
                  glutamine family amino acid metabolic process 74
                    proline metabolic process 13
                      proline biosynthetic process 7
                        L-proline biosynthetic process 7
                        negative regulation of proline biosynthetic process 0
                        proline salvage 0
                        regulation of proline biosynthetic process + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.