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ONTOLOGY REPORT - ANNOTATIONS


Term:tryptophan metabolic process
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Accession:GO:0006568 term browser browse the term
Definition:The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
Synonyms:exact_synonym: tryptophan metabolism
 xref: MIPS_funcat:01.01.09.06;   Wikipedia:Tryptophan


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tryptophan metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp7a ATPase copper transporting alpha JBrowse link X 77,076,085 77,193,644 RGD:1624291
G Tdo2 tryptophan 2,3-dioxygenase JBrowse link 2 180,897,059 180,914,919 RGD:2290190
RGD:2291804
RGD:2290313
'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Afmid arylformamidase JBrowse link 10 106,828,963 106,844,314 RGD:1600115
G Haao 3-hydroxyanthranilate 3,4-dioxygenase JBrowse link 6 7,045,145 7,059,227 RGD:13792537
RGD:1600115
G Ido1 indoleamine 2,3-dioxygenase 1 JBrowse link 16 72,216,326 72,228,098 RGD:13792537
G Ido2 indoleamine 2,3-dioxygenase 2 JBrowse link 16 72,232,852 72,291,227 RGD:13792537
G Kmo kynurenine 3-monooxygenase JBrowse link 13 93,684,324 93,715,378 RGD:1600115
G Kynu kynureninase JBrowse link 3 28,416,926 28,566,939 RGD:1600115
serotonin biosynthetic process from tryptophan term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:11353778
G Tph1 tryptophan hydroxylase 1 JBrowse link 1 102,669,868 102,699,442 RGD:625621
tryptophan catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acmsd aminocarboxymuconate semialdehyde decarboxylase JBrowse link 13 44,424,689 44,468,734 RGD:70243
G Haao 3-hydroxyanthranilate 3,4-dioxygenase JBrowse link 6 7,045,145 7,059,227 RGD:1600115
G Kmo kynurenine 3-monooxygenase JBrowse link 13 93,684,324 93,715,378 RGD:1600115
G Kynu kynureninase JBrowse link 3 28,416,926 28,566,939 RGD:1624291
tryptophan catabolic process to acetyl-CoA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kynu kynureninase JBrowse link 3 28,416,926 28,566,939 RGD:2303721
G Tdo2 tryptophan 2,3-dioxygenase JBrowse link 2 180,897,059 180,914,919 RGD:2303721
RGD:13792537
tryptophan catabolic process to kynurenine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Afmid arylformamidase JBrowse link 10 106,828,963 106,844,314 RGD:1624291
RGD:13792537
RGD:1600115
G Ido1 indoleamine 2,3-dioxygenase 1 JBrowse link 16 72,216,326 72,228,098 RGD:2290190
RGD:13792537
RGD:1624291
RGD:1600115
RGD:2290543
G Ido2 indoleamine 2,3-dioxygenase 2 JBrowse link 16 72,232,852 72,291,227 RGD:1600115
RGD:13792537
RGD:1624291
G Kynu kynureninase JBrowse link 3 28,416,926 28,566,939 RGD:13792537
G Tdo2 tryptophan 2,3-dioxygenase JBrowse link 2 180,897,059 180,914,919 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19312
    metabolic process 11535
      primary metabolic process 10404
        cellular amino acid metabolic process 269
          aromatic amino acid family metabolic process 33
            tryptophan metabolic process 11
              'de novo' NAD biosynthetic process from tryptophan + 6
              indoleacetic acid biosynthetic process via tryptophan + 0
              nicotinate nucleotide biosynthetic process from tryptophan 0
              positive regulation of tryptophan metabolic process + 0
              psilocybin biosynthetic process 0
              regulation of tryptophan metabolic process + 0
              serotonin biosynthetic process from tryptophan + 2
              tryptophan biosynthetic process 0
              tryptophan catabolic process + 8
Path 2
Term Annotations click to browse term
  biological_process 19312
    metabolic process 11535
      nitrogen compound metabolic process 9888
        organonitrogen compound metabolic process 6848
          amine metabolic process 92
            cellular amine metabolic process 83
              cellular biogenic amine metabolic process 47
                indolalkylamine metabolic process 11
                  tryptophan metabolic process 11
                    'de novo' NAD biosynthetic process from tryptophan + 6
                    indoleacetic acid biosynthetic process via tryptophan + 0
                    nicotinate nucleotide biosynthetic process from tryptophan 0
                    positive regulation of tryptophan metabolic process + 0
                    psilocybin biosynthetic process 0
                    regulation of tryptophan metabolic process + 0
                    serotonin biosynthetic process from tryptophan + 2
                    tryptophan biosynthetic process 0
                    tryptophan catabolic process + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.