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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular biogenic amine metabolic process
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Accession:GO:0006576 term browser browse the term
Definition:The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.
Synonyms:exact_synonym: biogenic amine metabolism


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cellular biogenic amine metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mecp2 methyl CpG binding protein 2 JBrowse link X 156,650,389 156,713,813 RGD:1624291
RGD:1600115
'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Afmid arylformamidase JBrowse link 10 106,828,963 106,844,314 RGD:1600115
G Haao 3-hydroxyanthranilate 3,4-dioxygenase JBrowse link 6 7,045,145 7,059,227 RGD:13792537
RGD:1600115
G Ido1 indoleamine 2,3-dioxygenase 1 JBrowse link 16 72,216,326 72,228,098 RGD:13792537
G Ido2 indoleamine 2,3-dioxygenase 2 JBrowse link 16 72,232,852 72,291,227 RGD:13792537
G Kmo kynurenine 3-monooxygenase JBrowse link 13 93,684,324 93,715,378 RGD:1600115
G Kynu kynureninase JBrowse link 3 28,416,926 28,566,939 RGD:1600115
choline catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dmgdh dimethylglycine dehydrogenase JBrowse link 2 23,289,376 23,370,360 RGD:632576
RGD:1624291
RGD:1600115
G Sardh sarcosine dehydrogenase JBrowse link 3 5,737,203 5,802,153 RGD:634034
ethanolamine metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chka choline kinase alpha JBrowse link 1 219,076,618 219,126,221 RGD:61551
histamine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hdc histidine decarboxylase JBrowse link 3 119,057,524 119,075,599 RGD:1600115
RGD:13792537
RGD:1624291
G Prg3 proteoglycan 3, pro eosinophil major basic protein 2 JBrowse link 3 72,395,194 72,401,254 RGD:1624291
histamine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hnmt histamine N-methyltransferase JBrowse link 3 905,111 937,038 RGD:1624291
RGD:1600115
histamine metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hdc histidine decarboxylase JBrowse link 3 119,057,524 119,075,599 RGD:2303726
RGD:2303735
RGD:2303728
RGD:2303727
G Trh thyrotropin releasing hormone JBrowse link 4 124,110,716 124,113,242 RGD:7241067
RGD:13792537
N-acylethanolamine metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B JBrowse link 15 32,888,233 32,906,861 RGD:1624291
G Gde1 glycerophosphodiester phosphodiesterase 1 JBrowse link 1 188,367,550 188,407,125 RGD:1624291
RGD:1600115
G Gdpd1 glycerophosphodiester phosphodiesterase domain containing 1 JBrowse link 10 74,334,972 74,376,332 RGD:1624291
RGD:13792537
RGD:1600115
G Naaa N-acylethanolamine acid amidase JBrowse link 14 17,283,262 17,302,364 RGD:1600115
RGD:1624291
G Napepld N-acyl phosphatidylethanolamine phospholipase D JBrowse link 4 9,965,323 10,004,650 RGD:1624291
RGD:13792537
nor-spermidine metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 JBrowse link 10 56,227,703 56,229,796 RGD:1624291
octopamine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dbh dopamine beta-hydroxylase JBrowse link 3 5,709,236 5,731,895 RGD:13792537
G Moxd1 monooxygenase, DBH-like 1 JBrowse link 1 22,124,498 22,206,565 RGD:13792537
G Moxd2 monooxygenase, DBH-like 2 JBrowse link 4 69,117,477 69,125,972 RGD:13792537
octopamine metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dbh dopamine beta-hydroxylase JBrowse link 3 5,709,236 5,731,895 RGD:1625401
phenylethylamine metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Maoa monoamine oxidase A JBrowse link X 6,554,698 6,620,722 RGD:1600709
polyamine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Azin1 antizyme inhibitor 1 JBrowse link 7 77,345,646 77,372,398 RGD:1600115
G Azin2 antizyme inhibitor 2 JBrowse link 5 147,120,128 147,148,576 RGD:1600115
G LOC100912604 spermidine synthase-like JBrowse link 3 14,588,818 14,591,980 RGD:13792537
G Oaz1 ornithine decarboxylase antizyme 1 JBrowse link 7 11,752,127 11,754,587 RGD:1600115
G Odc1 ornithine decarboxylase 1 JBrowse link 6 42,852,529 42,859,142 RGD:1600115
G Srm spermidine synthase JBrowse link 5 165,405,168 165,408,325 RGD:13792537
polyamine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Paox polyamine oxidase JBrowse link 1 212,578,444 212,603,722 RGD:7244190
RGD:1624291
G Sat1 spermidine/spermine N1-acetyl transferase 1 JBrowse link X 43,626,480 43,629,767 RGD:7244190
G Smox spermine oxidase JBrowse link 3 124,068,796 124,103,726 RGD:1624291
polyamine deacetylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hdac10 histone deacetylase 10 JBrowse link 7 130,102,335 130,109,036 RGD:1600115
RGD:1624291
G Hdac6 histone deacetylase 6 JBrowse link X 15,295,372 15,316,673 RGD:1624291
polyamine metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Amd1 adenosylmethionine decarboxylase 1 JBrowse link 20 45,384,000 45,399,694 RGD:1578320
G Oaz1 ornithine decarboxylase antizyme 1 JBrowse link 7 11,752,127 11,754,587 RGD:1600115
G Oaz2 ornithine decarboxylase antizyme 2 JBrowse link 8 71,216,011 71,229,788 RGD:1600115
G Odc1 ornithine decarboxylase 1 JBrowse link 6 42,852,529 42,859,142 RGD:1578320
G Sat1 spermidine/spermine N1-acetyl transferase 1 JBrowse link X 43,626,480 43,629,767 RGD:1599544
positive regulation of spermidine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Paox polyamine oxidase JBrowse link 1 212,578,444 212,603,722 RGD:1624291
putrescine acetylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 JBrowse link 10 56,227,703 56,229,796 RGD:1624291
putrescine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Odc1 ornithine decarboxylase 1 JBrowse link 6 42,852,529 42,859,142 RGD:1578320
RGD:7242912
G Paox polyamine oxidase JBrowse link 1 212,578,444 212,603,722 RGD:1624291
putrescine biosynthetic process from arginine, using agmatinase term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agmat agmatinase JBrowse link 5 160,306,754 160,321,951 RGD:13792537
putrescine biosynthetic process from ornithine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Azin1 antizyme inhibitor 1 JBrowse link 7 77,345,646 77,372,398 RGD:13792537
G Azin2 antizyme inhibitor 2 JBrowse link 5 147,120,128 147,148,576 RGD:13792537
G Odc1 ornithine decarboxylase 1 JBrowse link 6 42,852,529 42,859,142 RGD:1600115
RGD:13792537
RGD:1624291
G RGD1562036 similar to ornithine decarboxylase JBrowse link 5 148,432,213 148,444,188 RGD:13792537
putrescine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Paox polyamine oxidase JBrowse link 1 212,578,444 212,603,722 RGD:12790650
RGD:1624291
serotonin biosynthetic process from tryptophan term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:11353778
G Tph1 tryptophan hydroxylase 1 JBrowse link 1 102,669,868 102,699,442 RGD:625621
spermidine acetylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sat1 spermidine/spermine N1-acetyl transferase 1 JBrowse link X 43,626,480 43,629,767 RGD:7244190
RGD:13792537
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 JBrowse link 10 56,227,703 56,229,796 RGD:1624291
RGD:13792537
G Satl1 spermidine/spermine N1-acetyl transferase-like 1 JBrowse link X 83,772,526 83,788,556 RGD:13792537
spermidine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agmat agmatinase JBrowse link 5 160,306,754 160,321,951 RGD:1600115
G Amd1 adenosylmethionine decarboxylase 1 JBrowse link 20 45,384,000 45,399,694 RGD:1578320
RGD:1624291
RGD:13792537
RGD:7242912
RGD:7242911
G LOC100912604 spermidine synthase-like JBrowse link 3 14,588,818 14,591,980 RGD:13792537
G Srm spermidine synthase JBrowse link 5 165,405,168 165,408,325 RGD:1359042
RGD:13792537
RGD:1624291
RGD:7242928
RGD:7242920
spermidine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dhps deoxyhypusine synthase JBrowse link 19 26,184,665 26,188,755 RGD:2316236
G Paox polyamine oxidase JBrowse link 1 212,578,444 212,603,722 RGD:7244191
RGD:1624291
RGD:12790650
spermidine deacetylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hdac10 histone deacetylase 10 JBrowse link 7 130,102,335 130,109,036 RGD:1600115
RGD:1624291
G Hdac6 histone deacetylase 6 JBrowse link X 15,295,372 15,316,673 RGD:1624291
spermidine metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dhps deoxyhypusine synthase JBrowse link 19 26,184,665 26,188,755 RGD:1624291
spermine acetylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sat1 spermidine/spermine N1-acetyl transferase 1 JBrowse link X 43,626,480 43,629,767 RGD:7244190
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 JBrowse link 10 56,227,703 56,229,796 RGD:1624291
spermine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Amd1 adenosylmethionine decarboxylase 1 JBrowse link 20 45,384,000 45,399,694 RGD:1578320
RGD:1624291
RGD:13792537
RGD:7242912
RGD:7242911
G Sms spermine synthase JBrowse link X 40,363,646 40,415,110 RGD:7242928
RGD:13792537
spermine catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Paox polyamine oxidase JBrowse link 1 212,578,444 212,603,722 RGD:7244191
RGD:1624291
RGD:12790650
G Smox spermine oxidase JBrowse link 3 124,068,796 124,103,726 RGD:7244190
RGD:1624291
spermine metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sms spermine synthase JBrowse link X 40,363,646 40,415,110 RGD:1624291
tryptophan catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acmsd aminocarboxymuconate semialdehyde decarboxylase JBrowse link 13 44,424,689 44,468,734 RGD:70243
G Haao 3-hydroxyanthranilate 3,4-dioxygenase JBrowse link 6 7,045,145 7,059,227 RGD:1600115
G Kmo kynurenine 3-monooxygenase JBrowse link 13 93,684,324 93,715,378 RGD:1600115
G Kynu kynureninase JBrowse link 3 28,416,926 28,566,939 RGD:1624291
tryptophan catabolic process to acetyl-CoA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kynu kynureninase JBrowse link 3 28,416,926 28,566,939 RGD:2303721
G Tdo2 tryptophan 2,3-dioxygenase JBrowse link 2 180,897,059 180,914,919 RGD:2303721
RGD:13792537
tryptophan catabolic process to kynurenine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Afmid arylformamidase JBrowse link 10 106,828,963 106,844,314 RGD:1624291
RGD:13792537
RGD:1600115
G Ido1 indoleamine 2,3-dioxygenase 1 JBrowse link 16 72,216,326 72,228,098 RGD:2290190
RGD:13792537
RGD:1624291
RGD:1600115
RGD:2290543
G Ido2 indoleamine 2,3-dioxygenase 2 JBrowse link 16 72,232,852 72,291,227 RGD:1600115
RGD:13792537
RGD:1624291
G Kynu kynureninase JBrowse link 3 28,416,926 28,566,939 RGD:13792537
G Tdo2 tryptophan 2,3-dioxygenase JBrowse link 2 180,897,059 180,914,919 RGD:1600115
RGD:1624291
tryptophan metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp7a ATPase copper transporting alpha JBrowse link X 77,076,085 77,193,644 RGD:1624291
G Tdo2 tryptophan 2,3-dioxygenase JBrowse link 2 180,897,059 180,914,919 RGD:2290190
RGD:2291804
RGD:2290313

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19578
    metabolic process 11901
      nitrogen compound metabolic process 10025
        cellular nitrogen compound metabolic process 6385
          cellular amine metabolic process 84
            cellular biogenic amine metabolic process 47
              cellular biogenic amine biosynthetic process + 16
              cellular biogenic amine catabolic process + 15
              ethanolamine-containing compound metabolic process + 9
              histamine metabolic process + 4
              indolalkylamine metabolic process + 11
              nicotianamine metabolic process + 0
              phenylethylamine metabolic process + 1
              polyamine metabolic process + 19
Path 2
Term Annotations click to browse term
  biological_process 19578
    metabolic process 11901
      organic substance metabolic process 11299
        organonitrogen compound metabolic process 6969
          amine metabolic process 93
            cellular amine metabolic process 84
              cellular biogenic amine metabolic process 47
                cellular biogenic amine biosynthetic process + 16
                cellular biogenic amine catabolic process + 15
                ethanolamine-containing compound metabolic process + 9
                histamine metabolic process + 4
                indolalkylamine metabolic process + 11
                nicotianamine metabolic process + 0
                phenylethylamine metabolic process + 1
                polyamine metabolic process + 19
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.