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ONTOLOGY REPORT - ANNOTATIONS


Term:melanin metabolic process
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Accession:GO:0006582 term browser browse the term
Definition:The chemical reactions and pathways involving melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom.
Synonyms:exact_synonym: melanin metabolism


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melanin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:1624291
RGD:1600115
G Myo5a myosin VA JBrowse link 8 82,038,966 82,156,507 RGD:1624291
G Tyrp1 tyrosinase-related protein 1 JBrowse link 5 98,387,291 98,406,083 RGD:1624291
G Vhl von Hippel-Lindau tumor suppressor JBrowse link 4 145,580,869 145,587,835 RGD:1624291
melanin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asip agouti signaling protein JBrowse link 3 150,492,010 150,579,870 RGD:1624291
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 JBrowse link X 72,128,996 72,133,692 RGD:1624291
RGD:1600115
G Dct dopachrome tautomerase JBrowse link 15 103,208,174 103,245,033 RGD:1624291
G Ddt D-dopachrome tautomerase JBrowse link 20 13,827,153 13,829,624 RGD:1600115
G Mc1r melanocortin 1 receptor JBrowse link 19 56,215,420 56,219,987 RGD:1624291
G Myo5a myosin VA JBrowse link 8 82,038,966 82,156,507 RGD:1624291
RGD:1600115
G Oca2 OCA2 melanosomal transmembrane protein JBrowse link 1 114,661,970 114,987,433 RGD:1624291
G Pmel premelanosome protein JBrowse link 7 3,133,347 3,143,827 RGD:1624291
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 JBrowse link 8 103,503,982 103,554,905 RGD:1624291
RGD:1600115
G Tyr tyrosinase JBrowse link 1 151,012,598 151,106,802 RGD:1624291
RGD:13792537
melanin biosynthetic process from tyrosine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dct dopachrome tautomerase JBrowse link 15 103,208,174 103,245,033 RGD:1624291
negative regulation of melanin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mfsd12 major facilitator superfamily domain containing 12 JBrowse link 7 11,214,832 11,223,713 RGD:1624291
G Rapgef2 Rap guanine nucleotide exchange factor 2 JBrowse link 2 177,836,191 178,057,378 RGD:1624291
RGD:1600115
G Slc24a5 solute carrier family 24 member 5 JBrowse link 3 117,335,212 117,354,480 RGD:1624291
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
positive regulation of melanin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 JBrowse link 16 2,560,103 2,602,035 RGD:1624291
G Asip agouti signaling protein JBrowse link 3 150,492,010 150,579,870 RGD:1624291
RGD:13792537
G Cdh3 cadherin 3 JBrowse link 19 38,668,957 38,719,801 RGD:1624291
G Gipc1 GIPC PDZ domain containing family, member 1 JBrowse link 19 24,786,604 24,798,231 RGD:1600115
RGD:1624291
G Pmel premelanosome protein JBrowse link 7 3,133,347 3,143,827 RGD:1624291
G Tyrp1 tyrosinase-related protein 1 JBrowse link 5 98,387,291 98,406,083 RGD:1624291
regulation of melanin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc7a11 solute carrier family 7 member 11 JBrowse link 2 139,453,774 139,528,479 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19578
    metabolic process 11901
      secondary metabolic process 76
        melanin metabolic process 21
          melanin biosynthetic process + 19
          melanin catabolic process 0
          melanization defense response + 0
Path 2
Term Annotations click to browse term
  biological_process 19578
    metabolic process 11901
      cellular metabolic process 10737
        cellular aromatic compound metabolic process 5503
          phenol-containing compound metabolic process 122
            melanin metabolic process 21
              melanin biosynthetic process + 19
              melanin catabolic process 0
              melanization defense response + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.