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ONTOLOGY REPORT - ANNOTATIONS


Term:protein targeting to mitochondrion
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Accession:GO:0006626 term browser browse the term
Definition:The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein.
Synonyms:exact_synonym: protein import into mitochondrion;   protein targeting to mitochondria;   protein-mitochondrial targeting
 related_synonym: mitochondrial protein import;   mitochondrial translocation
 alt_id: GO:0043681


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protein targeting to mitochondrion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aip aryl-hydrocarbon receptor-interacting protein JBrowse link 1 219,361,859 219,373,924 RGD:1624291
RGD:1600115
G Bid BH3 interacting domain death agonist JBrowse link 4 153,439,812 153,465,247 RGD:1624291
G Fbxo7 F-box protein 7 JBrowse link 7 23,815,246 23,843,505 RGD:1624291
RGD:1600115
G Fis1 fission, mitochondrial 1 JBrowse link 12 22,750,485 22,765,324 RGD:1624291
G Gdap1 ganglioside-induced differentiation-associated-protein 1 JBrowse link 5 1,328,963 1,347,946 RGD:1624291
RGD:13792537
RGD:1600115
G LOC102556337 mitochondrial fission factor-like JBrowse link 9 90,880,586 90,908,848 RGD:12793033
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 10 35,333,859 35,374,364 RGD:2298783
G Mff mitochondrial fission factor JBrowse link 9 88,490,280 88,518,517 RGD:12793033
RGD:1624291
G Mfn2 mitofusin 2 JBrowse link 5 164,684,244 164,715,414 RGD:1624291
RGD:1600115
G Mgarp mitochondria-localized glutamic acid-rich protein JBrowse link 2 140,444,963 140,453,719 RGD:1624291
G Mterf4 mitochondrial transcription termination factor 4 JBrowse link 9 100,440,482 100,445,158 RGD:1624291
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta JBrowse link 18 36,985,709 37,421,383 RGD:2314541
G Timm8a1 translocase of inner mitochondrial membrane 8A1 JBrowse link X 105,351,714 105,355,722 RGD:724770
G Tomm20 translocase of outer mitochondrial membrane 20 JBrowse link 19 59,863,421 59,873,411 RGD:1624291
RGD:13838795
RGD:1600115
G Tomm22 translocase of outer mitochondrial membrane 22 JBrowse link 7 120,901,934 120,903,684 RGD:13838795
G Tomm34 translocase of outer mitochondrial membrane 34 JBrowse link 3 160,448,294 160,465,143 RGD:1624291
RGD:13792537
G Tomm40 translocase of outer mitochondrial membrane 40 JBrowse link 1 80,617,749 80,630,253 RGD:1303948
RGD:13838795
RGD:1624291
RGD:8554396
G Tomm70 translocase of outer mitochondrial membrane 70 JBrowse link 11 45,477,053 45,511,409 RGD:13838795
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta JBrowse link 7 75,573,553 75,598,295 RGD:727986
negative regulation of protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sirt4 sirtuin 4 JBrowse link 12 46,862,358 46,876,593 RGD:9586053
negative regulation of protein targeting to mitochondrion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bag3 BAG cochaperone 3 JBrowse link 1 199,941,258 199,965,191 RGD:5687132
G Bag4 BAG cochaperone 4 JBrowse link 16 71,057,709 71,075,874 RGD:1624291
RGD:1600115
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:1624291
G Nol3 nucleolar protein 3 JBrowse link 19 37,232,567 37,236,668 RGD:10047164
G Siah3 siah E3 ubiquitin protein ligase family member 3 JBrowse link 15 57,505,449 57,568,743 RGD:1624291
positive regulation of protein import into mitochondrial outer membrane term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdcd5 programmed cell death 5 JBrowse link 1 91,173,473 91,178,801 RGD:1624291
positive regulation of protein targeting to mitochondrion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fbxw7 F-box and WD repeat domain containing 7 JBrowse link 2 184,230,191 184,309,805 RGD:1624291
G Gsk3a glycogen synthase kinase 3 alpha JBrowse link 1 82,097,244 82,108,238 RGD:1624291
G Hspa1l heat shock protein family A (Hsp70) member 1 like JBrowse link 20 4,879,998 4,965,191 RGD:1624291
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 JBrowse link 2 54,857,688 54,893,404 RGD:1624291
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 JBrowse link 1 103,197,918 103,258,309 RGD:9835004
G Tomm7 translocase of outer mitochondrial membrane 7 JBrowse link 4 7,835,949 7,842,790 RGD:1624291
protein import into mitochondrial intermembrane space term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07014739.1 RGD:13792537
G AABR07067813.1 RGD:1600115
G Aifm1 apoptosis inducing factor, mitochondria associated 1 JBrowse link X 135,304,063 135,343,062 RGD:1624291
RGD:1600115
G Chchd4 coiled-coil-helix-coiled-coil-helix domain containing 4 JBrowse link 4 123,108,924 123,118,186 RGD:1600115
RGD:13792537
RGD:1624291
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:13792537
G LOC100361898 coiled-coil-helix-coiled-coil-helix domain containing 4 JBrowse link 1 248,402,889 248,403,604 RGD:1600115
RGD:13792537
protein import into mitochondrial matrix term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AC128303.1 RGD:13792537
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 JBrowse link 15 59,990,131 60,056,710 RGD:13792537
G Dnajc19 DnaJ heat shock protein family (Hsp40) member C19 JBrowse link 2 120,503,093 120,531,782 RGD:13792537
G Dnlz DNL-type zinc finger JBrowse link 3 3,796,480 3,798,467 RGD:13792537
G Grpel1 GrpE-like 1, mitochondrial JBrowse link 14 79,458,951 79,464,782 RGD:13792537
G Grpel2 GrpE-like 2, mitochondrial JBrowse link 18 57,037,995 57,050,234 RGD:13792537
G LOC100362432 mitochondrial import inner membrane translocase subunit Tim23-like JBrowse link 3 82,970,785 82,971,887 RGD:13792537
G LOC100910944 reactive oxygen species modulator 1-like JBrowse link 3 152,222,703 152,224,314 RGD:13792537
G LOC100911130 mitochondrial import inner membrane translocase subunit Tim17-B-like JBrowse link X 15,340,557 15,347,682 RGD:13792537
G Magmas-ps1 mitochondria-associated protein involved in granulocyte-macrophage colony-stimulating factor signal transduction, pseudogene 1 JBrowse link 10 91,752,860 91,753,380 RGD:13792537
G Pam16 presequence translocase associated motor 16 JBrowse link 10 11,146,359 11,153,936 RGD:1624291
RGD:13792537
G Romo1 reactive oxygen species modulator 1 JBrowse link 3 151,688,213 151,689,813 RGD:13792537
G Timm17a translocase of inner mitochondrial membrane 17A JBrowse link 13 52,124,641 52,136,127 RGD:13792537
G Timm17b translocase of inner mitochondrial membrane 17b JBrowse link X 15,441,369 15,448,452 RGD:13792537
G Timm21 translocase of inner mitochondrial membrane 21 JBrowse link 18 81,803,165 81,807,627 RGD:1624291
RGD:13792537
RGD:1600115
G Timm23 translocase of inner mitochondrial membrane 23 JBrowse link 16 8,324,038 8,350,067 RGD:13792537
G Timm44 translocase of inner mitochondrial membrane 44 JBrowse link 12 2,517,006 2,533,707 RGD:1600115
RGD:13792537
G Timm50 translocase of inner mitochondrial membrane 50 JBrowse link 1 85,470,810 85,480,813 RGD:13792537
G Tomm20 translocase of outer mitochondrial membrane 20 JBrowse link 19 59,863,421 59,873,411 RGD:13792537
G Tomm40 translocase of outer mitochondrial membrane 40 JBrowse link 1 80,617,749 80,630,253 RGD:1600115
RGD:13792537
G Tomm40l translocase of outer mitochondrial membrane 40 like JBrowse link 13 89,590,076 89,595,287 RGD:13792537
G Tomm7 translocase of outer mitochondrial membrane 7 JBrowse link 4 7,835,949 7,842,790 RGD:1600115
protein insertion into mitochondrial inner membrane term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agk acylglycerol kinase JBrowse link 4 68,483,345 68,561,518 RGD:1624291
G LOC100910944 reactive oxygen species modulator 1-like JBrowse link 3 152,222,703 152,224,314 RGD:13792537
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 JBrowse link 16 21,275,311 21,282,246 RGD:1624291
G Romo1 reactive oxygen species modulator 1 JBrowse link 3 151,688,213 151,689,813 RGD:13792537
G Timm10 translocase of inner mitochondrial membrane 10 JBrowse link 3 72,226,563 72,230,087 RGD:1624291
RGD:13792537
G Timm13 translocase of inner mitochondrial membrane 13 JBrowse link 7 11,677,340 11,678,443 RGD:13792537
G Timm22 translocase of inner mitochondrial membrane 22 JBrowse link 10 64,556,064 64,563,822 RGD:1600115
RGD:13792537
RGD:1624291
G Timm29 translocase of inner mitochondrial membrane 29 JBrowse link 8 22,625,874 22,628,843 RGD:1624291
RGD:13792537
G Timm9 translocase of inner mitochondrial membrane 9 JBrowse link 6 93,549,484 93,562,314 RGD:1624291
protein insertion into mitochondrial inner membrane from matrix term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cox18 cytochrome c oxidase assembly factor COX18 JBrowse link 14 19,434,728 19,446,379 RGD:1624291
RGD:13792537
G Maip1 matrix AAA peptidase interacting protein 1 JBrowse link 9 64,095,978 64,103,908 RGD:13792537
G Oxa1l OXA1L, mitochondrial inner membrane protein JBrowse link 15 33,004,957 33,012,584 RGD:13792537
protein insertion into mitochondrial outer membrane term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 JBrowse link 6 135,107,262 135,112,793 RGD:1624291
G Hspa4 heat shock protein family A (Hsp70) member 4 JBrowse link 10 38,601,624 38,642,397 RGD:1624291
RGD:1600115
G Samm50 SAMM50 sorting and assembly machinery component JBrowse link 7 125,058,966 125,082,506 RGD:1624291
RGD:13792537
G Tomm22 translocase of outer mitochondrial membrane 22 JBrowse link 7 120,901,934 120,903,684 RGD:1624291
protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Immp1l inner mitochondrial membrane peptidase subunit 1 JBrowse link 3 95,955,126 96,024,316 RGD:13792537
G Immp2l inner mitochondrial membrane peptidase subunit 2 JBrowse link 6 60,958,351 61,859,457 RGD:1624291
G Mipep mitochondrial intermediate peptidase JBrowse link 15 41,084,180 41,192,621 RGD:13792537
G Pmpca peptidase, mitochondrial processing subunit alpha JBrowse link 3 3,834,262 3,842,061 RGD:1600115
RGD:1624291
RGD:13792537
G Pmpcb peptidase, mitochondrial processing subunit beta JBrowse link 4 9,908,838 9,921,615 RGD:13463464
RGD:14995326
RGD:1624291
RGD:13792537
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 JBrowse link 1 190,555,177 190,585,741 RGD:13792537
regulation of protein targeting to mitochondrion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp5if1 ATP synthase inhibitory factor subunit 1 JBrowse link 5 150,719,570 150,723,287 RGD:1624291
G Bnip3l BCL2 interacting protein 3 like JBrowse link 15 43,643,897 43,667,123 RGD:1624291
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:1624291
G Parl presenilin associated, rhomboid-like JBrowse link 11 84,517,368 84,544,463 RGD:1624291
RGD:1600115
G Pink1 PTEN induced kinase 1 JBrowse link 5 156,677,146 156,689,258 RGD:1624291
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 10 46,570,996 46,593,021 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19335
    localization 6324
      establishment of localization 4866
        transport 4727
          mitochondrial transport 213
            protein targeting to mitochondrion 82
              negative regulation of protein targeting to mitochondrion + 6
              positive regulation of protein targeting to mitochondrion + 7
              protein import into mitochondrial intermembrane space 6
              protein import into mitochondrial matrix 22
              protein insertion into mitochondrial inner membrane + 12
              protein insertion into mitochondrial outer membrane + 5
              protein processing involved in protein targeting to mitochondrion + 7
              regulation of protein targeting to mitochondrion + 19
Path 2
Term Annotations click to browse term
  biological_process 19335
    localization 6324
      establishment of localization 4866
        transport 4727
          nitrogen compound transport 2246
            amide transport 1926
              peptide transport 1893
                protein transport 1836
                  intracellular protein transport 989
                    protein targeting 289
                      protein targeting to mitochondrion 82
                        negative regulation of protein targeting to mitochondrion + 6
                        positive regulation of protein targeting to mitochondrion + 7
                        protein import into mitochondrial intermembrane space 6
                        protein import into mitochondrial matrix 22
                        protein insertion into mitochondrial inner membrane + 12
                        protein insertion into mitochondrial outer membrane + 5
                        protein processing involved in protein targeting to mitochondrion + 7
                        regulation of protein targeting to mitochondrion + 19
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.