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ONTOLOGY REPORT - ANNOTATIONS


Term:unsaturated fatty acid biosynthetic process
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Accession:GO:0006636 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms.
Synonyms:exact_synonym: unsaturated fatty acid anabolism;   unsaturated fatty acid biosynthesis;   unsaturated fatty acid formation;   unsaturated fatty acid synthesis
 narrow_synonym: polyunsaturated fatty acid biosynthesis
 related_synonym: fatty acid desaturation
 xref: MetaCyc:PWY-762;   MetaCyc:PWY-782


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unsaturated fatty acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Decr2 2,4-dienoyl-CoA reductase 2 JBrowse link 10 15,451,850 15,460,227 RGD:1624291
G Elovl1 ELOVL fatty acid elongase 1 JBrowse link 5 137,255,868 137,260,486 RGD:1600115
G Elovl2 ELOVL fatty acid elongase 2 JBrowse link 17 21,382,461 21,422,413 RGD:1600115
G Elovl3 ELOVL fatty acid elongase 3 JBrowse link 1 265,883,353 265,887,181 RGD:1600115
G Elovl4 ELOVL fatty acid elongase 4 JBrowse link 8 91,310,690 91,338,625 RGD:1600115
G Elovl5 ELOVL fatty acid elongase 5 JBrowse link 8 85,220,941 85,287,449 RGD:1600115
G Elovl6 ELOVL fatty acid elongase 6 JBrowse link 2 234,187,490 234,296,124 RGD:1600115
G Elovl7 ELOVL fatty acid elongase 7 JBrowse link 2 40,373,211 40,386,643 RGD:1600115
G Fads1 fatty acid desaturase 1 JBrowse link 1 226,234,034 226,249,118 RGD:632758
RGD:1624291
RGD:1600115
G Fads2 fatty acid desaturase 2 JBrowse link 1 225,906,582 226,152,568 RGD:1600115
G Fads3 fatty acid desaturase 3 JBrowse link 1 226,091,774 226,108,332 RGD:1600115
G LOC102549542 elongation of very long chain fatty acids protein 6-like JBrowse link 2 234,375,172 234,486,639 RGD:1600115
G LOC681458 similar to stearoyl-coenzyme A desaturase 3 JBrowse link 1 263,968,156 264,003,991 RGD:13792537
G Scd stearoyl-CoA desaturase JBrowse link 1 264,159,966 264,173,061 RGD:10054074
RGD:13792537
RGD:1624291
RGD:10054069
G Scd2 stearoyl-Coenzyme A desaturase 2 JBrowse link 1 264,059,374 264,072,433 RGD:13792537
G Scd4 stearoyl-coenzyme A desaturase 4 JBrowse link 1 264,094,007 264,105,473 RGD:13792537
cyclooxygenase pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bdkrb1 bradykinin receptor B1 JBrowse link 6 129,437,423 129,441,553 RGD:1624291
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:1624291
RGD:1600115
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:1600115
RGD:1624291
G Sphk1 sphingosine kinase 1 JBrowse link 10 105,498,728 105,504,401 RGD:2311353
hepoxilin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox12 arachidonate 12-lipoxygenase, 12S type JBrowse link 10 56,851,734 56,864,049 RGD:8554649
RGD:13792537
G Alox12b arachidonate 12-lipoxygenase, 12R type JBrowse link 10 55,744,646 55,756,524 RGD:8554649
RGD:13792537
G Alox12e arachidonate 12-lipoxygenase, epidermal JBrowse link 10 56,927,676 56,935,141 RGD:13792537
G Alox15 arachidonate 15-lipoxygenase JBrowse link 10 56,953,692 56,962,145 RGD:5509794
RGD:13792537
RGD:8554649
G Alox15b arachidonate 15-lipoxygenase, type B JBrowse link 10 55,773,748 55,783,489 RGD:8554649
RGD:13792537
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:13792537
G Aloxe3 arachidonate lipoxygenase 3 JBrowse link 10 55,711,996 55,735,915 RGD:8554649
RGD:13792537
RGD:1624291
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:1600115
RGD:1624291
G Gstm2 glutathione S-transferase mu 2 JBrowse link 2 210,778,041 210,782,807 RGD:1600115
RGD:1624291
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:1600115
RGD:1624291
leukotriene A4 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:1624291
RGD:1600115
lipoxin A4 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox12 arachidonate 12-lipoxygenase, 12S type JBrowse link 10 56,851,734 56,864,049 RGD:1624291
RGD:1600115
G Alox15 arachidonate 15-lipoxygenase JBrowse link 10 56,953,692 56,962,145 RGD:1624291
RGD:1600115
G Alox15b arachidonate 15-lipoxygenase, type B JBrowse link 10 55,773,748 55,783,489 RGD:1600115
RGD:1624291
lipoxin B4 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox12 arachidonate 12-lipoxygenase, 12S type JBrowse link 10 56,851,734 56,864,049 RGD:1624291
RGD:1600115
lipoxin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:1600115
RGD:1624291
monounsaturated fatty acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC681458 similar to stearoyl-coenzyme A desaturase 3 JBrowse link 1 263,968,156 264,003,991 RGD:1600115
G Scd stearoyl-CoA desaturase JBrowse link 1 264,159,966 264,173,061 RGD:1624291
G Scd2 stearoyl-Coenzyme A desaturase 2 JBrowse link 1 264,059,374 264,072,433 RGD:1624291
RGD:1600115
G Scd4 stearoyl-coenzyme A desaturase 4 JBrowse link 1 264,094,007 264,105,473 RGD:1624291
negative regulation of prostaglandin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pibf1 progesterone immunomodulatory binding factor 1 JBrowse link 15 83,494,110 83,663,202 RGD:1624291
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
positive regulation of prostaglandin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:2306959
RGD:13792537
G Avp arginine vasopressin JBrowse link 3 123,117,482 123,119,460 RGD:2300349
G Avpr1a arginine vasopressin receptor 1A JBrowse link 7 67,341,366 67,345,290 RGD:2300349
G Cd74 CD74 molecule JBrowse link 18 56,071,420 56,080,851 RGD:1624291
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1600115
RGD:1624291
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 10 35,333,859 35,374,364 RGD:2304243
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:1642461
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:1624291
positive regulation of unsaturated fatty acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcd1 ATP binding cassette subfamily D member 1 JBrowse link X 157,073,860 157,095,652 RGD:1624291
G Abcd2 ATP binding cassette subfamily D member 2 JBrowse link 7 132,294,564 132,343,169 RGD:1624291
RGD:1600115
prostaglandin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07034131.1 RGD:13792537
G AABR07054614.1 RGD:1600115
G Cd74 CD74 molecule JBrowse link 18 56,071,420 56,080,851 RGD:1624291
RGD:1600115
G Daglb diacylglycerol lipase, beta JBrowse link 12 13,113,073 13,157,748 RGD:1600115
RGD:1624291
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:1624291
G Edn2 endothelin 2 JBrowse link 5 139,098,472 139,106,396 RGD:1624291
RGD:1600115
G Hpgds hematopoietic prostaglandin D synthase JBrowse link 4 95,945,356 95,970,666 RGD:68838
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:1624291
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:1624291
RGD:1600115
G Pla2g4f phospholipase A2, group IVF JBrowse link 3 112,068,617 112,083,978 RGD:1624291
G Pnpla8 patatin-like phospholipase domain containing 8 JBrowse link 6 64,224,870 64,288,465 RGD:1624291
G Prxl2b peroxiredoxin like 2B JBrowse link 5 172,304,799 172,307,402 RGD:1624291
RGD:8552775
RGD:1600115
G Ptgds prostaglandin D2 synthase JBrowse link 3 2,686,125 2,689,059 RGD:8553429
RGD:1624291
G Ptges prostaglandin E synthase JBrowse link 3 9,727,408 9,738,752 RGD:67929
RGD:13792537
RGD:1624291
G Ptges3 prostaglandin E synthase 3 JBrowse link 7 2,479,267 2,497,024 RGD:5688071
RGD:13792537
RGD:1600115
RGD:1624291
G Ptges3l1 prostaglandin E synthase 3-like 1 JBrowse link X 45,410,545 45,419,817 RGD:13792537
G Ptgis prostaglandin I2 synthase JBrowse link 3 163,950,746 163,986,129 RGD:727270
RGD:1624291
RGD:13792537
RGD:1600115
RGD:8693629
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:2300259
RGD:1600115
RGD:1624291
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:2300259
RGD:1624291
G Tbxas1 thromboxane A synthase 1 JBrowse link 4 66,624,181 66,846,745 RGD:1624291
regulation of prostaglandin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fabp5 fatty acid binding protein 5 JBrowse link 2 93,981,662 93,985,322 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19578
    metabolic process 11901
      biosynthetic process 5967
        organic substance biosynthetic process 5872
          lipid biosynthetic process 590
            fatty acid biosynthetic process 144
              unsaturated fatty acid biosynthetic process 58
                (R)-2-hydroxy-alpha-linolenic acid biosynthetic process 0
                hepoxilin biosynthetic process 10
                leukotriene A4 biosynthetic process 1
                leukotriene B4 biosynthetic process 0
                lipoxin biosynthetic process + 4
                monounsaturated fatty acid biosynthetic process 4
                positive regulation of unsaturated fatty acid biosynthetic process + 10
                prostanoid biosynthetic process + 30
                regulation of unsaturated fatty acid biosynthetic process + 13
Path 2
Term Annotations click to browse term
  biological_process 19578
    metabolic process 11901
      small molecule metabolic process 1824
        organic acid metabolic process 1053
          oxoacid metabolic process 1026
            carboxylic acid metabolic process 979
              monocarboxylic acid metabolic process 642
                fatty acid metabolic process 408
                  fatty acid biosynthetic process 144
                    unsaturated fatty acid biosynthetic process 58
                      (R)-2-hydroxy-alpha-linolenic acid biosynthetic process 0
                      hepoxilin biosynthetic process 10
                      leukotriene A4 biosynthetic process 1
                      leukotriene B4 biosynthetic process 0
                      lipoxin biosynthetic process + 4
                      monounsaturated fatty acid biosynthetic process 4
                      positive regulation of unsaturated fatty acid biosynthetic process + 10
                      prostanoid biosynthetic process + 30
                      regulation of unsaturated fatty acid biosynthetic process + 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.