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ONTOLOGY REPORT - ANNOTATIONS


Term:acyl-CoA metabolic process
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Accession:GO:0006637 term browser browse the term
Definition:The chemical reactions and pathways involving acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group.
Synonyms:exact_synonym: acyl-CoA metabolism


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acyl-CoA metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acadsb acyl-CoA dehydrogenase, short/branched chain JBrowse link 1 201,981,362 202,022,771 RGD:631739
G Acnat1 acyl-coenzyme A amino acid N-acyltransferase 1 JBrowse link 5 64,710,885 64,718,500 RGD:13792537
G Acnat2 acyl-coenzyme A amino acid N-acyltransferase 2 JBrowse link 5 64,669,998 64,674,250 RGD:1600115
RGD:13792537
G Acot1 acyl-CoA thioesterase 1 JBrowse link 6 107,485,088 107,493,082 RGD:1600115
RGD:1624291
RGD:13792537
G Acot11 acyl-CoA thioesterase 11 JBrowse link 5 126,347,478 126,395,655 RGD:13792537
G Acot12 acyl-CoA thioesterase 12 JBrowse link 2 20,857,056 20,901,656 RGD:633789
RGD:13792537
G Acot2 acyl-CoA thioesterase 2 JBrowse link 6 107,460,596 107,468,324 RGD:2315867
RGD:13792537
RGD:1624291
RGD:1600115
G Acot3 acyl-CoA thioesterase 3 JBrowse link 6 107,531,508 107,537,446 RGD:13792537
RGD:1624291
G Acot4 acyl-CoA thioesterase 4 JBrowse link 6 107,517,668 107,522,952 RGD:1624291
RGD:13792537
G Acot5 acyl-CoA thioesterase 5 JBrowse link 6 107,550,904 107,557,688 RGD:13792537
G Acot6 acyl-CoA thioesterase 6 JBrowse link 6 107,581,357 107,590,431 RGD:13792537
G Acot7 acyl-CoA thioesterase 7 JBrowse link 5 169,357,582 169,450,215 RGD:13792537
G Acot8 acyl-CoA thioesterase 8 JBrowse link 3 161,260,837 161,272,495 RGD:1624291
RGD:13792537
RGD:70235
RGD:1600115
G Acot9 acyl-CoA thioesterase 9 JBrowse link X 43,543,069 43,592,200 RGD:1624291
RGD:13792537
G Acsm2 acyl-CoA synthetase medium-chain family member 2 JBrowse link 1 189,289,957 189,329,007 RGD:13792537
G Acsm3 acyl-CoA synthetase medium-chain family member 3 JBrowse link 1 189,514,504 189,541,233 RGD:13792537
G Acsm4 acyl-CoA synthetase medium-chain family member 4 JBrowse link 1 189,432,604 189,458,799 RGD:1299602
RGD:13792537
G Acsm5 acyl-CoA synthetase medium-chain family member 5 JBrowse link 1 189,240,955 189,270,422 RGD:13792537
G Baat bile acid CoA:amino acid N-acyltransferase JBrowse link 5 64,768,397 64,777,368 RGD:1624291
RGD:13792537
G Dbi diazepam binding inhibitor, acyl-CoA binding protein JBrowse link 13 36,147,667 36,156,076 RGD:728881
G Dbil5 diazepam binding inhibitor-like 5 JBrowse link 10 64,375,926 64,376,938 RGD:61789
G Gcdh glutaryl-CoA dehydrogenase JBrowse link 19 26,000,497 26,006,970 RGD:1598697
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial JBrowse link 1 275,843,823 275,906,880 RGD:1624291
RGD:1600115
G Gpat4 glycerol-3-phosphate acyltransferase 4 JBrowse link 16 73,615,949 73,649,769 RGD:1624291
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase JBrowse link 5 154,294,841 154,308,582 RGD:1599519
G Hnf4a hepatocyte nuclear factor 4, alpha JBrowse link 3 159,902,441 159,965,003 RGD:1625002
G Oxsm 3-oxoacyl-ACP synthase, mitochondrial JBrowse link 15 10,462,380 10,466,496 RGD:1624291
acetyl-CoA biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acat1 acetyl-CoA acetyltransferase 1 JBrowse link 8 58,166,990 58,195,884 RGD:1624291
G Acly ATP citrate lyase JBrowse link 10 88,392,248 88,442,845 RGD:631761
RGD:13792537
RGD:1600115
RGD:1624291
G Acss1 acyl-CoA synthetase short-chain family member 1 JBrowse link 3 146,420,346 146,470,293 RGD:1624291
G Acss2 acyl-CoA synthetase short-chain family member 2 JBrowse link 3 151,032,925 151,075,856 RGD:1624291
G Mlycd malonyl-CoA decarboxylase JBrowse link 19 52,032,950 52,048,773 RGD:1600790
RGD:13792537
RGD:1624291
RGD:1600115
G Ppcs phosphopantothenoylcysteine synthetase JBrowse link 5 138,466,298 138,470,108 RGD:1624291
acetyl-CoA biosynthetic process from acetate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acss1 acyl-CoA synthetase short-chain family member 1 JBrowse link 3 146,420,346 146,470,293 RGD:1600115
acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dlat dihydrolipoamide S-acetyltransferase JBrowse link 8 55,062,549 55,087,832 RGD:1599112
G Dld dihydrolipoamide dehydrogenase JBrowse link 6 50,597,677 50,618,694 RGD:1599112
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 JBrowse link X 37,329,779 37,343,410 RGD:1599112
RGD:13792537
RGD:1624291
RGD:1600115
G Pdha1l1 pyruvate dehydrogenase (lipoamide) alpha 1-like 1 JBrowse link 16 88,344,440 88,347,335 RGD:1600115
G Pdha2 pyruvate dehydrogenase E1 subunit alpha 2 JBrowse link 2 246,736,449 246,737,997 RGD:1599112
RGD:13792537
G Pdhb pyruvate dehydrogenase E1 subunit beta JBrowse link 15 18,540,826 18,546,855 RGD:1599112
RGD:13792537
RGD:1624291
RGD:1600115
G Pdhx pyruvate dehydrogenase complex, component X JBrowse link 3 92,910,300 92,933,725 RGD:1600115
G Pdk4 pyruvate dehydrogenase kinase 4 JBrowse link 4 30,546,772 30,556,774 RGD:729541
acetyl-CoA catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acat1 acetyl-CoA acetyltransferase 1 JBrowse link 8 58,166,990 58,195,884 RGD:1624291
G Nudt7 nudix hydrolase 7 JBrowse link 19 46,455,745 46,470,070 RGD:1624291
acetyl-CoA metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acaa2 acetyl-CoA acyltransferase 2 JBrowse link 18 70,733,872 70,762,395 RGD:2317620
G Acaca acetyl-CoA carboxylase alpha JBrowse link 10 71,519,392 71,719,910 RGD:1600115
RGD:1624291
G Acacb acetyl-CoA carboxylase beta JBrowse link 12 48,127,149 48,238,969 RGD:1624291
G Acly ATP citrate lyase JBrowse link 10 88,392,248 88,442,845 RGD:2317315
G Acot12 acyl-CoA thioesterase 12 JBrowse link 2 20,857,056 20,901,656 RGD:1624291
RGD:1600115
G Cs citrate synthase JBrowse link 7 2,752,680 2,778,963 RGD:2306824
RGD:2306828
RGD:2306825
G Fasn fatty acid synthase JBrowse link 10 109,987,735 110,005,901 RGD:2317315
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 JBrowse link 2 52,427,351 52,445,082 RGD:13792537
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 JBrowse link 2 200,452,623 200,480,785 RGD:13792537
benzoyl-CoA metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Glyat glycine-N-acyltransferase JBrowse link 1 229,060,125 229,081,113 RGD:1624291
RGD:1600115
fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gcdh glutaryl-CoA dehydrogenase JBrowse link 19 26,000,497 26,006,970 RGD:1598697
isopentenyl diphosphate biosynthetic process, mevalonate pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mvd mevalonate diphosphate decarboxylase JBrowse link 19 55,258,910 55,268,933 RGD:2316852
RGD:13792537
RGD:1600115
G Mvk mevalonate kinase JBrowse link 12 47,904,266 47,920,457 RGD:2316852
RGD:13792537
RGD:1600115
G Pmvk phosphomevalonate kinase JBrowse link 2 188,784,329 188,793,890 RGD:2316852
RGD:13792537
RGD:1600115
L-lysine catabolic process to acetyl-CoA via L-pipecolate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pipox pipecolic acid and sarcosine oxidase JBrowse link 10 64,951,986 64,964,865 RGD:1624291
RGD:13792537
L-lysine catabolic process to acetyl-CoA via saccharopine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aadat aminoadipate aminotransferase JBrowse link 16 32,832,001 32,868,680 RGD:1600115
G Aass aminoadipate-semialdehyde synthase JBrowse link 4 50,152,005 50,208,935 RGD:1600115
G Dlst dihydrolipoamide S-succinyltransferase JBrowse link 6 108,936,534 108,961,322 RGD:1600115
L-methylmalonyl-CoA metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mcee methylmalonyl CoA epimerase JBrowse link 1 125,229,487 125,252,692 RGD:1624291
RGD:13792537
long-chain fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acsl1 acyl-CoA synthetase long-chain family member 1 JBrowse link 16 48,937,456 49,003,898 RGD:2312800
G Acsl4 acyl-CoA synthetase long-chain family member 4 JBrowse link X 113,596,247 113,660,024 RGD:2312800
G Acsl5 acyl-CoA synthetase long-chain family member 5 JBrowse link 1 276,240,703 276,290,012 RGD:2312800
G Acsl6 acyl-CoA synthetase long-chain family member 6 JBrowse link 10 39,654,771 39,717,592 RGD:2312800
G Elovl1 ELOVL fatty acid elongase 1 JBrowse link 5 137,255,868 137,260,486 RGD:1600115
G Elovl3 ELOVL fatty acid elongase 3 JBrowse link 1 265,883,353 265,887,181 RGD:1600115
G Elovl4 ELOVL fatty acid elongase 4 JBrowse link 8 91,310,690 91,338,625 RGD:1600115
G Elovl5 ELOVL fatty acid elongase 5 JBrowse link 8 85,220,941 85,287,449 RGD:1600115
G Elovl6 ELOVL fatty acid elongase 6 JBrowse link 2 234,187,490 234,296,124 RGD:1600115
G Elovl7 ELOVL fatty acid elongase 7 JBrowse link 2 40,373,211 40,386,643 RGD:1600115
G LOC102549542 elongation of very long chain fatty acids protein 6-like JBrowse link 2 234,375,172 234,486,639 RGD:1600115
long-chain fatty-acyl-CoA catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acot7 acyl-CoA thioesterase 7 JBrowse link 5 169,357,582 169,450,215 RGD:1624291
long-chain fatty-acyl-CoA metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dgat1 diacylglycerol O-acyltransferase 1 JBrowse link 7 117,566,363 117,576,735 RGD:1624291
RGD:1600115
G Dgat2 diacylglycerol O-acyltransferase 2 JBrowse link 1 164,113,459 164,143,818 RGD:1624291
G Far1 fatty acyl CoA reductase 1 JBrowse link 1 178,351,674 178,412,838 RGD:1600115
RGD:13792537
RGD:1624291
G Far2 fatty acyl CoA reductase 2 JBrowse link 4 182,446,400 182,563,485 RGD:1624291
RGD:13792537
G Them5 thioesterase superfamily member 5 JBrowse link 2 195,582,781 195,588,000 RGD:1624291
malonyl-CoA biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acaca acetyl-CoA carboxylase alpha JBrowse link 10 71,519,392 71,719,910 RGD:1600115
G Acacb acetyl-CoA carboxylase beta JBrowse link 12 48,127,149 48,238,969 RGD:1624291
malonyl-CoA catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mlycd malonyl-CoA decarboxylase JBrowse link 19 52,032,950 52,048,773 RGD:1624291
RGD:13792537
RGD:1600115
medium-chain fatty-acyl-CoA catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acot7 acyl-CoA thioesterase 7 JBrowse link 5 169,357,582 169,450,215 RGD:1624291
medium-chain fatty-acyl-CoA metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acsm2 acyl-CoA synthetase medium-chain family member 2 JBrowse link 1 189,289,957 189,329,007 RGD:1624291
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 JBrowse link 18 44,810,462 44,897,677 RGD:1624291
RGD:1600115
mitochondrial acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mpc1 mitochondrial pyruvate carrier 1 JBrowse link 1 53,026,608 53,038,229 RGD:1624291
G Mpc2 mitochondrial pyruvate carrier 2 JBrowse link 13 83,680,527 83,700,491 RGD:1624291
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 JBrowse link X 37,329,779 37,343,410 RGD:1624291
propionyl-CoA biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acat1 acetyl-CoA acetyltransferase 1 JBrowse link 8 58,166,990 58,195,884 RGD:1624291
regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdk1 pyruvate dehydrogenase kinase 1 JBrowse link 3 58,530,870 58,561,494 RGD:1600115
RGD:1624291
G Pdk2 pyruvate dehydrogenase kinase 2 JBrowse link 10 82,838,270 82,852,758 RGD:1600115
RGD:1624291
G Pdk3 pyruvate dehydrogenase kinase 3 JBrowse link X 62,836,131 62,904,114 RGD:1624291
G Pdk4 pyruvate dehydrogenase kinase 4 JBrowse link 4 30,546,772 30,556,774 RGD:1600115
RGD:1624291
regulation of acyl-CoA biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Snca synuclein alpha JBrowse link 4 90,782,412 90,883,236 RGD:1624291
succinyl-CoA metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acot4 acyl-CoA thioesterase 4 JBrowse link 6 107,517,668 107,522,952 RGD:1624291
G Dlst dihydrolipoamide S-succinyltransferase JBrowse link 6 108,936,534 108,961,322 RGD:1600115
RGD:1624291
G Ogdh oxoglutarate dehydrogenase JBrowse link 14 86,414,924 86,481,903 RGD:2306877
RGD:1624291
G Sucla2 succinate-CoA ligase ADP-forming subunit beta JBrowse link 15 55,461,695 55,516,954 RGD:2306915
RGD:13792537
G Suclg1 succinate-CoA ligase GDP/ADP-forming subunit alpha JBrowse link 4 101,181,315 101,210,692 RGD:2306879
RGD:13792537
RGD:2306915
G Suclg2 succinate-CoA ligase GDP-forming subunit beta JBrowse link 4 127,552,100 127,824,970 RGD:2306879
RGD:13792537
RGD:2306915
tryptophan catabolic process to acetyl-CoA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kynu kynureninase JBrowse link 3 28,416,926 28,566,939 RGD:2303721
G Tdo2 tryptophan 2,3-dioxygenase JBrowse link 2 180,897,059 180,914,919 RGD:2303721
RGD:13792537
very long-chain fatty-acyl-CoA catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcd1 ATP binding cassette subfamily D member 1 JBrowse link X 157,073,860 157,095,652 RGD:1624291
RGD:1600115
very long-chain fatty-acyl-CoA metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 JBrowse link 18 44,810,462 44,897,677 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    metabolic process 11555
      organic substance metabolic process 10949
        thioester metabolic process 88
          acyl-CoA metabolic process 88
            2-hydroxybenzoyl-CoA metabolic process + 0
            L-methylmalonyl-CoA metabolic process + 1
            acetyl-CoA metabolic process + 37
            acyl-CoA biosynthetic process + 34
            benzoyl-CoA metabolic process + 1
            fatty-acyl-CoA metabolic process + 22
            malonyl-CoA metabolic process + 3
            succinyl-CoA metabolic process + 6
Path 2
Term Annotations click to browse term
  biological_process 19336
    metabolic process 11555
      cellular metabolic process 10567
        cellular aromatic compound metabolic process 5482
          nucleobase-containing compound metabolic process 5256
            nucleobase-containing small molecule metabolic process 575
              nucleoside phosphate metabolic process 496
                nucleotide metabolic process 489
                  purine nucleotide metabolic process 402
                    purine ribonucleotide metabolic process 377
                      acyl-CoA metabolic process 88
                        2-hydroxybenzoyl-CoA metabolic process + 0
                        L-methylmalonyl-CoA metabolic process + 1
                        acetyl-CoA metabolic process + 37
                        acyl-CoA biosynthetic process + 34
                        benzoyl-CoA metabolic process + 1
                        fatty-acyl-CoA metabolic process + 22
                        malonyl-CoA metabolic process + 3
                        succinyl-CoA metabolic process + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.