ONTOLOGY REPORT - ANNOTATIONS


Term:phosphatidylcholine biosynthetic process
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Accession:GO:0006656 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
Synonyms:exact_synonym: phosphatidylcholine anabolism;   phosphatidylcholine biosynthesis;   phosphatidylcholine formation;   phosphatidylcholine synthesis


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phosphatidylcholine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:1624291
RGD:1600115
G Apoa2 apolipoprotein A2 JBrowse link 13 89,596,872 89,598,805 RGD:1624291
RGD:1600115
G Cept1 choline/ethanolamine phosphotransferase 1 JBrowse link 2 209,118,140 209,162,071 RGD:1624291
G Chka choline kinase alpha JBrowse link 1 219,076,618 219,126,221 RGD:1624291
RGD:1600115
G Chkb choline kinase beta JBrowse link 7 130,404,818 130,408,813 RGD:1624291
G Chpt1 choline phosphotransferase 1 JBrowse link 7 29,019,518 29,070,928 RGD:1624291
G Fabp5 fatty acid binding protein 5 JBrowse link 2 93,981,662 93,985,322 RGD:1624291
G Fgf7 fibroblast growth factor 7 JBrowse link 3 118,315,859 118,368,464 RGD:68696
G Gpat4 glycerol-3-phosphate acyltransferase 4 JBrowse link 16 73,615,949 73,649,769 RGD:1624291
RGD:1600115
G Lcat lecithin cholesterol acyltransferase JBrowse link 19 37,913,333 37,916,799 RGD:1624291
RGD:1600115
G Pcyt1a phosphate cytidylyltransferase 1, choline, alpha JBrowse link 11 71,547,865 71,592,037 RGD:70012
RGD:1624291
RGD:729598
G Pemt phosphatidylethanolamine N-methyltransferase JBrowse link 10 46,339,821 46,404,640 RGD:729486
RGD:13792537
RGD:1600115
G Phka1 phosphorylase kinase regulatory subunit alpha 1 JBrowse link X 72,377,020 72,515,385 RGD:724642
G Slc27a1 solute carrier family 27 member 1 JBrowse link 16 19,997,823 20,016,193 RGD:1600115
RGD:13792537
RGD:1624291
CDP-choline pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cept1 choline/ethanolamine phosphotransferase 1 JBrowse link 2 209,118,140 209,162,071 RGD:1600115
G Chka choline kinase alpha JBrowse link 1 219,076,618 219,126,221 RGD:1600115
G Chkb choline kinase beta JBrowse link 7 130,404,818 130,408,813 RGD:1600115
G Chpt1 choline phosphotransferase 1 JBrowse link 7 29,019,518 29,070,928 RGD:1600115
G Pcyt1a phosphate cytidylyltransferase 1, choline, alpha JBrowse link 11 71,547,865 71,592,037 RGD:8553740
G Pcyt1b phosphate cytidylyltransferase 1, choline, beta JBrowse link X 62,727,691 62,821,199 RGD:1600115
G Phka1 phosphorylase kinase regulatory subunit alpha 1 JBrowse link X 72,377,020 72,515,385 RGD:1600115
negative regulation of phosphatidylcholine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lpcat1 lysophosphatidylcholine acyltransferase 1 JBrowse link 1 32,379,431 32,429,917 RGD:1624291
RGD:1600115
positive regulation of phosphatidylcholine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acsl3 acyl-CoA synthetase long-chain family member 3 JBrowse link 9 84,569,601 84,593,565 RGD:1624291
RGD:1600115
G Capn2 calpain 2 JBrowse link 13 100,878,649 100,928,811 RGD:13792658
G Rab38 RAB38, member RAS oncogene family JBrowse link 1 152,072,716 152,153,449 RGD:13524861
regulation of phosphatidylcholine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fabp3 fatty acid binding protein 3 JBrowse link 5 148,528,854 148,535,597 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17941
    metabolic process 10685
      organic substance metabolic process 10138
        organonitrogen compound metabolic process 6354
          phosphatidylcholine metabolic process 41
            phosphatidylcholine biosynthetic process 20
              CDP-choline pathway 7
              negative regulation of phosphatidylcholine biosynthetic process + 1
              phosphatidylcholine biosynthesis from choline and CDP-diacylglycerol 0
              phosphatidylcholine biosynthesis from phosphatidylethanolamine 0
              phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine 0
              phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine 0
              phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline 0
              phosphatidylcholine biosynthesis from sn-glycero-3-phosphocholine 0
              positive regulation of phosphatidylcholine biosynthetic process + 3
              regulation of phosphatidylcholine biosynthetic process + 5
Path 2
Term Annotations click to browse term
  biological_process 17941
    metabolic process 10685
      cellular metabolic process 9780
        phosphorus metabolic process 3087
          phosphate-containing compound metabolic process 3067
            phospholipid metabolic process 363
              glycerophospholipid metabolic process 241
                phosphatidylcholine metabolic process 41
                  phosphatidylcholine biosynthetic process 20
                    CDP-choline pathway 7
                    negative regulation of phosphatidylcholine biosynthetic process + 1
                    phosphatidylcholine biosynthesis from choline and CDP-diacylglycerol 0
                    phosphatidylcholine biosynthesis from phosphatidylethanolamine 0
                    phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine 0
                    phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine 0
                    phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline 0
                    phosphatidylcholine biosynthesis from sn-glycero-3-phosphocholine 0
                    positive regulation of phosphatidylcholine biosynthetic process + 3
                    regulation of phosphatidylcholine biosynthetic process + 5
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.