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ONTOLOGY REPORT - ANNOTATIONS


Term:ceramide metabolic process
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Accession:GO:0006672 term browser browse the term
Definition:The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.
Synonyms:exact_synonym: ceramide metabolism


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ceramide metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asah2 N-acylsphingosine amidohydrolase 2 JBrowse link 1 250,557,042 250,665,083 RGD:1600115
RGD:1624291
G Cerk ceramide kinase JBrowse link 7 127,015,162 127,058,056 RGD:1624291
G Cert1 ceramide transporter 1 JBrowse link 2 27,365,145 27,469,797 RGD:1624291
G Cln8 CLN8, transmembrane ER and ERGIC protein JBrowse link 16 79,828,321 79,838,212 RGD:1624291
RGD:1600115
G Fut7 fucosyltransferase 7 JBrowse link 3 2,637,281 2,646,497 RGD:1624291
G Htra2 HtrA serine peptidase 2 JBrowse link 4 113,883,671 113,886,833 RGD:5688365
G LOC367454 similar to Alpha-(1,3)-fucosyltransferase (Galactoside 3-L-fucosyltransferase) (Fucosyltransferase 6) (FUCT-VI) JBrowse link 9 10,309,050 10,318,899 RGD:1624291
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 JBrowse link 9 53,110,628 53,120,454 RGD:1624291
RGD:13792537
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 JBrowse link 7 3,242,991 3,246,085 RGD:1624291
RGD:13792537
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 JBrowse link 10 86,545,910 86,554,478 RGD:1600115
RGD:13792537
RGD:1624291
G Pla2g15 phospholipase A2, group XV JBrowse link 19 38,129,666 38,146,958 RGD:1304489
RGD:1624291
G Plpp1 phospholipid phosphatase 1 JBrowse link 2 44,664,076 44,726,820 RGD:1624291
RGD:15090855
RGD:15090857
RGD:1600115
G Plpp2 phospholipid phosphatase 2 JBrowse link 7 13,062,168 13,070,281 RGD:1624291
RGD:1600115
G Plpp3 phospholipid phosphatase 3 JBrowse link 5 124,690,214 124,765,499 RGD:1624291
RGD:1600115
G Sgpl1 sphingosine-1-phosphate lyase 1 JBrowse link 20 30,699,936 30,769,178 RGD:1624291
RGD:1600115
G Smpd1 sphingomyelin phosphodiesterase 1 JBrowse link 1 170,383,682 170,387,525 RGD:1624291
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link 19 38,237,963 38,321,572 RGD:1624291
RGD:1600115
G Smpd5 sphingomyelin phosphodiesterase 5 JBrowse link 7 117,351,694 117,354,241 RGD:1624291
ceramide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agk acylglycerol kinase JBrowse link 4 68,483,345 68,561,518 RGD:1624291
G Alox12b arachidonate 12-lipoxygenase, 12R type JBrowse link 10 55,744,646 55,756,524 RGD:1600115
RGD:1624291
G Aloxe3 arachidonate lipoxygenase 3 JBrowse link 10 55,711,996 55,735,915 RGD:1624291
RGD:1600115
G Asah1 N-acylsphingosine amidohydrolase 1 JBrowse link 16 53,998,604 54,030,006 RGD:1600115
RGD:1624291
G Asah2 N-acylsphingosine amidohydrolase 2 JBrowse link 1 250,557,042 250,665,083 RGD:13838803
RGD:1624291
RGD:13838793
G Cers1 ceramide synthase 1 JBrowse link 16 20,845,580 20,860,789 RGD:1624291
G Cers2 ceramide synthase 2 JBrowse link 2 196,487,656 196,495,930 RGD:1624291
RGD:13792537
G Cers3 ceramide synthase 3 JBrowse link 1 127,706,618 127,781,041 RGD:1624291
RGD:13792537
G Cers4 ceramide synthase 4 JBrowse link 12 4,439,750 4,474,759 RGD:1624291
RGD:13792537
G Cers5 ceramide synthase 5 JBrowse link 7 141,386,391 141,424,375 RGD:1624291
RGD:13792537
G Cers6 ceramide synthase 6 JBrowse link 3 55,094,240 55,338,370 RGD:1624291
RGD:13792537
G Cyp4f39 cytochrome P450, family 4, subfamily f, polypeptide 39 JBrowse link 7 14,435,024 14,514,960 RGD:1624291
RGD:1600115
G Degs1 delta(4)-desaturase, sphingolipid 1 JBrowse link 13 100,665,265 100,672,731 RGD:1624291
RGD:13792537
G Degs2 delta(4)-desaturase, sphingolipid 2 JBrowse link 6 132,591,968 132,608,600 RGD:1624291
RGD:13792537
G Elovl1 ELOVL fatty acid elongase 1 JBrowse link 5 137,255,868 137,260,486 RGD:1624291
G Fa2h fatty acid 2-hydroxylase JBrowse link 19 43,545,380 43,596,788 RGD:1600115
RGD:1624291
G Gba glucosylceramidase beta JBrowse link 2 188,511,781 188,522,602 RGD:1624291
G LOC498300 similar to degenerative spermatocyte homolog JBrowse link 13 99,369,102 99,374,051 RGD:13792537
G P2rx1 purinergic receptor P2X 1 JBrowse link 10 59,566,268 59,581,328 RGD:1624291
G P2rx7 purinergic receptor P2X 7 JBrowse link 12 39,353,613 39,396,042 RGD:1624291
G RGD1564463 similar to Mdes protein JBrowse link 13 99,374,006 99,395,804 RGD:13792537
G Samd8 sterile alpha motif domain containing 8 JBrowse link 15 2,685,504 2,731,062 RGD:1624291
RGD:13792537
G Sgms1 sphingomyelin synthase 1 JBrowse link 1 250,692,448 250,951,685 RGD:1624291
RGD:13792537
G Sgms2 sphingomyelin synthase 2 JBrowse link 2 236,458,276 236,530,667 RGD:1624291
RGD:13792537
RGD:1600115
G Smpd1 sphingomyelin phosphodiesterase 1 JBrowse link 1 170,383,682 170,387,525 RGD:1601344
RGD:13792537
RGD:1624291
G Smpd2 sphingomyelin phosphodiesterase 2 JBrowse link 20 46,212,070 46,215,183 RGD:1581395
G Smpd4 sphingomyelin phosphodiesterase 4 JBrowse link 11 87,522,971 87,546,687 RGD:1624291
RGD:13792537
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 JBrowse link 17 11,856,525 11,895,566 RGD:1624291
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 JBrowse link 6 111,334,408 111,417,960 RGD:1624291
G Sptssa serine palmitoyltransferase, small subunit A JBrowse link 6 75,540,132 75,551,545 RGD:1624291
G Sptssb serine palmitoyltransferase, small subunit B JBrowse link 2 166,654,036 166,682,325 RGD:1624291
RGD:13792537
G Tlcd3b TLC domain containing 3B JBrowse link 1 198,252,208 198,265,840 RGD:1624291
ceramide catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acer1 alkaline ceramidase 1 JBrowse link 9 10,061,978 10,093,588 RGD:1624291
G Acer2 alkaline ceramidase 2 JBrowse link 5 105,230,540 105,279,732 RGD:1624291
G Acer3 alkaline ceramidase 3 JBrowse link 1 163,160,987 163,263,621 RGD:1624291
G Asah1 N-acylsphingosine amidohydrolase 1 JBrowse link 16 53,998,604 54,030,006 RGD:1600115
RGD:1624291
G Asah2 N-acylsphingosine amidohydrolase 2 JBrowse link 1 250,557,042 250,665,083 RGD:13838800
RGD:13792537
RGD:1624291
RGD:13838794
RGD:13838793
G Cel carboxyl ester lipase JBrowse link 3 7,134,021 7,141,522 RGD:1624291
RGD:1600115
galactosylceramide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G B3galt1 Beta-1,3-galactosyltransferase 1 JBrowse link 3 53,699,409 54,269,612 RGD:1624291
G B3galt2 Beta-1,3-galactosyltransferase 2 JBrowse link 13 60,435,946 60,444,957 RGD:1624291
G B4galt3 beta-1,4-galactosyltransferase 3 JBrowse link 13 89,643,847 89,649,880 RGD:1624291
G Fa2h fatty acid 2-hydroxylase JBrowse link 19 43,545,380 43,596,788 RGD:1600115
RGD:13825191
RGD:1624291
G Gal3st1 galactose-3-O-sulfotransferase 1 JBrowse link 14 84,231,473 84,247,371 RGD:1624291
G Ugt8 UDP glycosyltransferase 8 JBrowse link 2 229,644,373 229,718,678 RGD:1600115
galactosylceramide catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Galc galactosylceramidase JBrowse link 6 122,177,195 122,239,411 RGD:1624291
RGD:13792537
G Gba3 glucosylceramidase beta 3 JBrowse link 14 64,390,793 64,535,213 RGD:1624291
G Psap prosaposin JBrowse link 20 29,831,302 29,856,876 RGD:1600115
RGD:1624291
ganglioside biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07013843.1 RGD:13792537
G B3galt4 Beta-1,3-galactosyltransferase 4 JBrowse link 20 5,446,104 5,447,679 RGD:1600115
RGD:1624291
G B4galnt1 beta-1,4-N-acetyl-galactosaminyl transferase 1 JBrowse link 7 70,439,273 70,459,556 RGD:1624291
RGD:1600115
G St6galnac3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 JBrowse link 2 259,379,653 259,918,813 RGD:13792537
G St6galnac4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 JBrowse link 3 11,607,103 11,619,595 RGD:13792537
G St6galnac5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 JBrowse link 2 258,025,177 259,150,709 RGD:13792537
G St6galnac6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 JBrowse link 3 11,620,050 11,641,460 RGD:1624291
RGD:13792537
G St8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 JBrowse link 1 135,336,374 135,406,699 RGD:1624291
G St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 JBrowse link 18 59,748,766 59,755,257 RGD:1624291
G St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 JBrowse link 9 103,117,705 103,207,154 RGD:1624291
G St8sia6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 JBrowse link 17 80,960,785 81,002,830 RGD:1624291
ganglioside biosynthetic process via lactosylceramide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G B4galt5 beta-1,4-galactosyltransferase 5 JBrowse link 3 164,039,731 164,055,561 RGD:1624291
G B4galt6 beta-1,4-galactosyltransferase 6 JBrowse link 18 15,462,913 15,525,584 RGD:1600115
RGD:1624291
ganglioside catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gm2a GM2 ganglioside activator JBrowse link 10 40,438,394 40,450,927 RGD:1624291
G Hexa hexosaminidase subunit alpha JBrowse link 8 64,325,435 64,350,775 RGD:1624291
G Hexb hexosaminidase subunit beta JBrowse link 2 27,983,925 28,003,260 RGD:1624291
RGD:1600115
G Neu1 neuraminidase 1 JBrowse link 20 4,610,995 4,615,258 RGD:13792537
G Neu2 neuraminidase 2 JBrowse link 9 94,702,095 94,724,903 RGD:1600115
RGD:13792537
RGD:1624291
G Neu3 neuraminidase 3 JBrowse link 1 164,803,574 164,814,777 RGD:1624291
RGD:13792537
RGD:1600115
G Neu4 neuraminidase 4 JBrowse link 9 101,284,902 101,290,558 RGD:1624291
RGD:13792537
G NEWGENE_1308624 sialidase 4 JBrowse link 9 101,003,455 101,008,365 RGD:13792537
ganglioside metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cln6 CLN6, transmembrane ER protein JBrowse link 8 67,733,215 67,748,170 RGD:1624291
G Gm2a GM2 ganglioside activator JBrowse link 10 40,438,394 40,450,927 RGD:1598995
G Itgb8 integrin subunit beta 8 JBrowse link 6 147,089,280 147,172,846 RGD:1624291
glucosylceramide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fa2h fatty acid 2-hydroxylase JBrowse link 19 43,545,380 43,596,788 RGD:1600115
RGD:1624291
G Ugcg UDP-glucose ceramide glucosyltransferase JBrowse link 5 76,376,722 76,419,564 RGD:13792537
RGD:1624291
RGD:1600115
glucosylceramide catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gba glucosylceramidase beta JBrowse link 2 188,511,781 188,522,602 RGD:1624291
G Gba2 glucosylceramidase beta 2 JBrowse link 5 59,068,081 59,079,719 RGD:1600115
RGD:1624291
G Gba3 glucosylceramidase beta 3 JBrowse link 14 64,390,793 64,535,213 RGD:1624291
glucosylceramide metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Psap prosaposin JBrowse link 20 29,831,302 29,856,876 RGD:1600115
glycosylceramide catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gba3 glucosylceramidase beta 3 JBrowse link 14 64,390,793 64,535,213 RGD:13792537
G Gla galactosidase, alpha JBrowse link X 105,405,915 105,417,331 RGD:1624291
RGD:13792537
G Naga alpha-N-acetylgalactosaminidase JBrowse link 7 123,563,047 123,572,074 RGD:13792537
glycosylceramide metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G St6galnac3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 JBrowse link 2 259,379,653 259,918,813 RGD:1624291
RGD:1600115
G St6galnac6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 JBrowse link 3 11,620,050 11,641,460 RGD:1624291
lactosylceramide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G B4galt6 beta-1,4-galactosyltransferase 6 JBrowse link 18 15,462,913 15,525,584 RGD:1600115
RGD:1624291
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 JBrowse link 9 53,110,628 53,120,454 RGD:1624291
RGD:13792537
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 JBrowse link 7 3,242,991 3,246,085 RGD:1624291
RGD:13792537
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 JBrowse link 10 86,545,910 86,554,478 RGD:1624291
RGD:13792537
RGD:1600115
G Sphk1 sphingosine kinase 1 JBrowse link 10 105,498,728 105,504,401 RGD:1600115
RGD:1624291
positive regulation of ceramide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccn1 cellular communication network factor 1 JBrowse link 2 251,529,354 251,532,312 RGD:1624291
RGD:1600115
G Pla2g6 phospholipase A2 group VI JBrowse link 7 120,519,479 120,559,716 RGD:6482750
G Prkcd protein kinase C, delta JBrowse link 16 6,655,131 6,675,746 RGD:1624291
RGD:1600115
G Sirt3 sirtuin 3 JBrowse link 1 213,613,502 213,636,061 RGD:1624291
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link 19 38,237,963 38,321,572 RGD:10041064
G Sphk2 sphingosine kinase 2 JBrowse link 1 101,692,972 101,700,604 RGD:1624291
positive regulation of glucosylceramide catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Prkcd protein kinase C, delta JBrowse link 16 6,655,131 6,675,746 RGD:1624291
RGD:1600115
regulation of ceramide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Samd8 sterile alpha motif domain containing 8 JBrowse link 15 2,685,504 2,731,062 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19332
    metabolic process 11554
      nitrogen compound metabolic process 9892
        organonitrogen compound metabolic process 6852
          sphingolipid metabolic process 135
            ceramide metabolic process 93
              ceramide biosynthetic process + 61
              ceramide catabolic process + 22
              ganglioside metabolic process + 23
              glycosylceramide metabolic process + 17
              lactosylceramide metabolic process + 1
Path 2
Term Annotations click to browse term
  biological_process 19332
    metabolic process 11554
      organic substance metabolic process 10949
        lipid metabolic process 1300
          cellular lipid metabolic process 987
            membrane lipid metabolic process 183
              sphingolipid metabolic process 135
                ceramide metabolic process 93
                  ceramide biosynthetic process + 61
                  ceramide catabolic process + 22
                  ganglioside metabolic process + 23
                  glycosylceramide metabolic process + 17
                  lactosylceramide metabolic process + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.