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ONTOLOGY REPORT - ANNOTATIONS


Term:sphingomyelin metabolic process
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Accession:GO:0006684 term browser browse the term
Definition:The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine.
Synonyms:exact_synonym: sphingomyelin metabolism


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sphingomyelin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 JBrowse link 17 79,347,505 79,359,349 RGD:9068941
G SMPD1 sphingomyelin phosphodiesterase 1 JBrowse link 11 6,205,278 6,209,950 RGD:9068941
G SMPD2 sphingomyelin phosphodiesterase 2 JBrowse link 6 111,292,130 111,295,408 RGD:9068941
G SMPD3 sphingomyelin phosphodiesterase 3 JBrowse link 16 68,129,034 68,219,625 RGD:9068941
positive regulation of sphingomyelin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 JBrowse link 17 79,347,505 79,359,349 RGD:9068941
G PRKCD protein kinase C delta JBrowse link 3 54,330,328 54,357,910 RGD:9068941
sphingomyelin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PEMT phosphatidylethanolamine N-methyltransferase JBrowse link 17 38,651,026 38,737,202 RGD:9068941
G SAMD8 sterile alpha motif domain containing 8 JBrowse link 10 74,292,923 74,374,307 RGD:9068941
G SGMS1 sphingomyelin synthase 1 JBrowse link 10 49,076,976 49,392,937 RGD:9068941
G SGMS2 sphingomyelin synthase 2 JBrowse link 4 110,902,572 110,992,887 RGD:9068941
G SPTLC1 serine palmitoyltransferase long chain base subunit 1 JBrowse link 9 91,185,574 91,213,003 RGD:9068941
G SPTLC2 serine palmitoyltransferase long chain base subunit 2 JBrowse link 14 77,266,545 77,370,663 RGD:9068941
sphingomyelin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 JBrowse link 17 79,347,505 79,359,349 RGD:9068941
G SMPD1 sphingomyelin phosphodiesterase 1 JBrowse link 11 6,205,278 6,209,950 RGD:9068941
G SMPD2 sphingomyelin phosphodiesterase 2 JBrowse link 6 111,292,130 111,295,408 RGD:9068941
G SMPD3 sphingomyelin phosphodiesterase 3 JBrowse link 16 68,129,034 68,219,625 RGD:9068941
G SMPDL3A sphingomyelin phosphodiesterase acid like 3A JBrowse link 6 124,701,094 124,723,469 RGD:9068941
G SMPDL3B sphingomyelin phosphodiesterase acid like 3B JBrowse link 1 28,234,761 28,259,079 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15758
    cellular process 15087
      cellular metabolic process 9943
        cellular lipid metabolic process 1010
          phospholipid metabolic process 424
            sphingomyelin metabolic process 13
              sphingomyelin biosynthetic process 6
              sphingomyelin catabolic process + 7
Path 2
Term Annotations click to browse term
  biological_process 15758
    metabolic process 10722
      organic substance metabolic process 10201
        lipid metabolic process 1329
          cellular lipid metabolic process 1010
            membrane lipid metabolic process 204
              sphingolipid metabolic process 156
                sphingomyelin metabolic process 13
                  sphingomyelin biosynthetic process 6
                  sphingomyelin catabolic process + 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.