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ONTOLOGY REPORT - ANNOTATIONS


Term:sphingomyelin metabolic process
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Accession:GO:0006684 term browser browse the term
Definition:The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine.
Synonyms:exact_synonym: sphingomyelin metabolism


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sphingomyelin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 JBrowse link NW_004955506 3,151,133 3,154,613 RGD:9068941
G Smpd1 sphingomyelin phosphodiesterase 1 JBrowse link NW_004955414 22,117,929 22,121,744 RGD:9068941
G Smpd2 sphingomyelin phosphodiesterase 2 JBrowse link NW_004955411 34,481,431 34,484,423 RGD:9068941
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link NW_004955484 8,207,686 8,298,164 RGD:9068941
positive regulation of sphingomyelin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 JBrowse link NW_004955506 3,151,133 3,154,613 RGD:9068941
G Prkcd protein kinase C delta JBrowse link NW_004955430 3,125,066 3,151,857 RGD:9068941
sphingomyelin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pemt phosphatidylethanolamine N-methyltransferase JBrowse link NW_004955577 365,031 443,138 RGD:9068941
G Samd8 sterile alpha motif domain containing 8 JBrowse link NW_004955437 16,900,756 16,969,042 RGD:9068941
G Sgms1 sphingomyelin synthase 1 JBrowse link NW_004955425 5,507,905 5,819,357 RGD:9068941
G Sgms2 sphingomyelin synthase 2 JBrowse link NW_004955496 1,909,347 1,955,004 RGD:9068941
G Sptlc1 serine palmitoyltransferase long chain base subunit 1 JBrowse link NW_004955515 57,711 161,012 RGD:9068941
G Sptlc2 serine palmitoyltransferase long chain base subunit 2 JBrowse link NW_004955438 1,385,431 1,491,534 RGD:9068941
sphingomyelin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 JBrowse link NW_004955506 3,151,133 3,154,613 RGD:9068941
G Smpd1 sphingomyelin phosphodiesterase 1 JBrowse link NW_004955414 22,117,929 22,121,744 RGD:9068941
G Smpd2 sphingomyelin phosphodiesterase 2 JBrowse link NW_004955411 34,481,431 34,484,423 RGD:9068941
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link NW_004955484 8,207,686 8,298,164 RGD:9068941
G Smpd4 sphingomyelin phosphodiesterase 4 JBrowse link NW_004955442 19,184,794 19,210,999 RGD:9068941
G Smpdl3a sphingomyelin phosphodiesterase acid like 3A JBrowse link NW_004955436 4,655,730 4,663,993 RGD:9068941
G Smpdl3b sphingomyelin phosphodiesterase acid like 3B JBrowse link NW_004955452 7,114,746 7,138,924 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14616
    cellular process 14021
      cellular metabolic process 9423
        cellular lipid metabolic process 969
          phospholipid metabolic process 421
            sphingomyelin metabolic process 14
              sphingomyelin biosynthetic process 6
              sphingomyelin catabolic process + 8
Path 2
Term Annotations click to browse term
  biological_process 14616
    metabolic process 10124
      organic substance metabolic process 9625
        lipid metabolic process 1273
          cellular lipid metabolic process 969
            membrane lipid metabolic process 205
              sphingolipid metabolic process 156
                sphingomyelin metabolic process 14
                  sphingomyelin biosynthetic process 6
                  sphingomyelin catabolic process + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.