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ONTOLOGY REPORT - ANNOTATIONS


Term:sphingomyelin metabolic process
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Accession:GO:0006684 term browser browse the term
Definition:The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine.
Synonyms:exact_synonym: sphingomyelin metabolism


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sphingomyelin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SMPD2 sphingomyelin phosphodiesterase 2 JBrowse link 12 66,347,628 66,350,322 RGD:13508589
G SMPD3 sphingomyelin phosphodiesterase 3 JBrowse link 5 81,089,657 81,172,173 RGD:13508589
positive regulation of sphingomyelin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PRKCD protein kinase C delta JBrowse link 20 36,723,491 36,751,982 RGD:13508589
sphingomyelin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SGMS1 sphingomyelin synthase 1 JBrowse link 26 37,243,388 37,472,806 RGD:13508589
G SGMS2 sphingomyelin synthase 2 JBrowse link 32 28,277,195 28,407,761 RGD:13508589
G SPTLC1 serine palmitoyltransferase long chain base subunit 1 JBrowse link 1 94,997,240 95,062,424 RGD:13508589
G SPTLC2 serine palmitoyltransferase long chain base subunit 2 JBrowse link 8 50,291,797 50,401,202 RGD:13508589
sphingomyelin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 JBrowse link 9 1,887,093 1,894,728 RGD:13508589
G SMPD1 sphingomyelin phosphodiesterase 1 JBrowse link 21 29,714,418 29,719,035 RGD:13508589
G SMPD2 sphingomyelin phosphodiesterase 2 JBrowse link 12 66,347,628 66,350,322 RGD:13508589
G SMPD3 sphingomyelin phosphodiesterase 3 JBrowse link 5 81,089,657 81,172,173 RGD:13508589
G SMPD4 sphingomyelin phosphodiesterase 4 JBrowse link 26 30,397,687 30,419,072 RGD:13508589
G SMPDL3A sphingomyelin phosphodiesterase acid like 3A JBrowse link 1 62,091,947 62,110,081 RGD:13508589
G SMPDL3B sphingomyelin phosphodiesterase acid like 3B JBrowse link 2 72,427,085 72,450,547 RGD:13508589
G XKR8 XK related 8 JBrowse link 2 72,419,950 72,426,315 RGD:13508589

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14457
    cellular process 13633
      cellular metabolic process 8189
        cellular lipid metabolic process 682
          phospholipid metabolic process 287
            sphingomyelin metabolic process 13
              sphingomyelin biosynthetic process 4
              sphingomyelin catabolic process + 9
Path 2
Term Annotations click to browse term
  biological_process 14457
    metabolic process 9082
      organic substance metabolic process 8574
        lipid metabolic process 903
          cellular lipid metabolic process 682
            membrane lipid metabolic process 140
              sphingolipid metabolic process 99
                sphingomyelin metabolic process 13
                  sphingomyelin biosynthetic process 4
                  sphingomyelin catabolic process + 9
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.