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ONTOLOGY REPORT - ANNOTATIONS


Term:sphingomyelin metabolic process
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Accession:GO:0006684 term browser browse the term
Definition:The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine.
Synonyms:exact_synonym: sphingomyelin metabolism


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sphingomyelin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 JBrowse link 17 79,730,919 79,742,926 RGD:2290271
G SMPD1 sphingomyelin phosphodiesterase 1 JBrowse link 11 6,390,474 6,394,998 RGD:2290271
G SMPD2 sphingomyelin phosphodiesterase 2 JBrowse link 6 109,440,721 109,443,922 RGD:2290271
G SMPD3 sphingomyelin phosphodiesterase 3 JBrowse link 16 68,358,327 68,448,703 RGD:2290271
positive regulation of sphingomyelin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 JBrowse link 17 79,730,919 79,742,926 RGD:2290271
G PRKCD protein kinase C delta JBrowse link 3 53,161,209 53,192,717 RGD:2290271
sphingomyelin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PEMT phosphatidylethanolamine N-methyltransferase JBrowse link 17 17,505,561 17,591,987 RGD:2290271
G SAMD8 sterile alpha motif domain containing 8 JBrowse link 10 75,099,575 75,182,123 RGD:2290271
G SGMS1 sphingomyelin synthase 1 JBrowse link 10 50,305,600 50,623,956 RGD:2290271
G SGMS2 sphingomyelin synthase 2 JBrowse link 4 107,823,645 107,915,047 RGD:2290271
G SPTLC1 serine palmitoyltransferase long chain base subunit 1 JBrowse link 9 92,031,141 92,115,413 RGD:2290271
G SPTLC2 serine palmitoyltransferase long chain base subunit 2 JBrowse link 14 77,505,997 77,616,663 RGD:2290271
sphingomyelin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 JBrowse link 17 79,730,919 79,742,926 RGD:2290271
G SMPD1 sphingomyelin phosphodiesterase 1 JBrowse link 11 6,390,474 6,394,998 RGD:2290271
G SMPD2 sphingomyelin phosphodiesterase 2 JBrowse link 6 109,440,721 109,443,922 RGD:2290271
G SMPD3 sphingomyelin phosphodiesterase 3 JBrowse link 16 68,358,327 68,448,703 RGD:2290271
G SMPD4 sphingomyelin phosphodiesterase 4 JBrowse link 2 130,151,392 130,181,757 RGD:2290271
G SMPDL3A sphingomyelin phosphodiesterase acid like 3A JBrowse link 6 122,788,456 122,809,720 RGD:2290271
G SMPDL3B sphingomyelin phosphodiesterase acid like 3B JBrowse link 1 27,934,955 27,959,152 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18105
    cellular process 17122
      cellular metabolic process 10975
        cellular lipid metabolic process 1097
          phospholipid metabolic process 450
            sphingomyelin metabolic process 14
              sphingomyelin biosynthetic process 6
              sphingomyelin catabolic process + 8
Path 2
Term Annotations click to browse term
  biological_process 18105
    metabolic process 11848
      organic substance metabolic process 11270
        lipid metabolic process 1443
          cellular lipid metabolic process 1097
            membrane lipid metabolic process 214
              sphingolipid metabolic process 165
                sphingomyelin metabolic process 14
                  sphingomyelin biosynthetic process 6
                  sphingomyelin catabolic process + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.