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ONTOLOGY REPORT - ANNOTATIONS


Term:sphingomyelin metabolic process
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Accession:GO:0006684 term browser browse the term
Definition:The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine.
Synonyms:exact_synonym: sphingomyelin metabolism


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sphingomyelin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 JBrowse link 11 118,988,181 118,993,221 RGD:2290270
G Smpd2 sphingomyelin phosphodiesterase 2, neutral JBrowse link 10 41,487,172 41,490,370 RGD:2290270
G Smpd3 sphingomyelin phosphodiesterase 3, neutral JBrowse link 8 106,252,548 106,337,965 RGD:2290270
G Smpd5 sphingomyelin phosphodiesterase 5 JBrowse link 15 76,294,278 76,296,896 RGD:2290270
positive regulation of sphingomyelin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 JBrowse link 11 118,988,181 118,993,221 RGD:2290270
G Prkcd protein kinase C, delta JBrowse link 14 30,595,353 30,626,414 RGD:2290270
sphingomyelin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pemt phosphatidylethanolamine N-methyltransferase JBrowse link 11 59,970,614 60,046,561 RGD:2290270
G Samd8 sterile alpha motif domain containing 8 JBrowse link 14 21,750,531 21,798,726 RGD:2290270
G Sgms1 sphingomyelin synthase 1 JBrowse link 19 32,122,727 32,389,885 RGD:2290270
G Sgms2 sphingomyelin synthase 2 JBrowse link 3 131,318,985 131,491,406 RGD:2290270
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 JBrowse link 13 53,332,748 53,377,417 RGD:2290270
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 JBrowse link 12 87,305,058 87,388,355 RGD:2290270
sphingomyelin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 JBrowse link 11 118,988,181 118,993,221 RGD:2290270
G Smpd1 sphingomyelin phosphodiesterase 1, acid lysosomal JBrowse link 7 105,554,360 105,558,389 RGD:2290270
G Smpd2 sphingomyelin phosphodiesterase 2, neutral JBrowse link 10 41,487,172 41,490,370 RGD:2290270
G Smpd3 sphingomyelin phosphodiesterase 3, neutral JBrowse link 8 106,252,548 106,337,965 RGD:2290270
G Smpd4 sphingomyelin phosphodiesterase 4 JBrowse link 16 17,619,354 17,644,830 RGD:2290270
G Smpdl3a sphingomyelin phosphodiesterase, acid-like 3A JBrowse link 10 57,794,544 57,811,830 RGD:2290270
G Smpdl3b sphingomyelin phosphodiesterase, acid-like 3B JBrowse link 4 132,732,966 132,757,171 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23162
    cellular process 16953
      cellular metabolic process 9695
        cellular lipid metabolic process 965
          phospholipid metabolic process 361
            sphingomyelin metabolic process 15
              sphingomyelin biosynthetic process 6
              sphingomyelin catabolic process + 8
Path 2
Term Annotations click to browse term
  biological_process 23162
    metabolic process 10900
      organic substance metabolic process 10349
        lipid metabolic process 1300
          cellular lipid metabolic process 965
            membrane lipid metabolic process 175
              sphingolipid metabolic process 131
                sphingomyelin metabolic process 15
                  sphingomyelin biosynthetic process 6
                  sphingomyelin catabolic process + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.