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ONTOLOGY REPORT - ANNOTATIONS


Term:sphingomyelin metabolic process
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Accession:GO:0006684 term browser browse the term
Definition:The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine.
Synonyms:exact_synonym: sphingomyelin metabolism


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sphingomyelin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 JBrowse link 10 108,095,131 108,099,483 RGD:1600115
RGD:1624291
G Smpd2 sphingomyelin phosphodiesterase 2 JBrowse link 20 46,212,070 46,215,183 RGD:13792537
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link 19 38,237,963 38,321,572 RGD:1624291
RGD:13792537
G Smpd5 sphingomyelin phosphodiesterase 5 JBrowse link 7 117,351,694 117,354,241 RGD:13792537
positive regulation of sphingomyelin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 JBrowse link 10 108,095,131 108,099,483 RGD:1600115
RGD:1624291
G Prkcd protein kinase C, delta JBrowse link 16 6,655,131 6,675,746 RGD:1624291
RGD:1600115
sphingomyelin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pemt phosphatidylethanolamine N-methyltransferase JBrowse link 10 46,339,821 46,404,640 RGD:1624291
G Sgms1 sphingomyelin synthase 1 JBrowse link 1 250,692,448 250,951,685 RGD:1600115
RGD:13792537
RGD:1624291
G Sgms2 sphingomyelin synthase 2 JBrowse link 2 236,458,276 236,530,667 RGD:1624291
RGD:13792537
RGD:1600115
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 JBrowse link 17 11,856,525 11,895,566 RGD:1624291
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 JBrowse link 6 111,334,408 111,417,960 RGD:1624291
sphingomyelin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 JBrowse link 10 108,095,131 108,099,483 RGD:1600115
G Smpd1 sphingomyelin phosphodiesterase 1 JBrowse link 1 170,383,682 170,387,525 RGD:1624291
RGD:13792537
G Smpd2 sphingomyelin phosphodiesterase 2 JBrowse link 20 46,212,070 46,215,183 RGD:1624291
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link 19 38,237,963 38,321,572 RGD:1624291
RGD:1600115
G Smpd4 sphingomyelin phosphodiesterase 4 JBrowse link 11 87,522,971 87,546,687 RGD:1624291
RGD:13792537
G Smpdl3a sphingomyelin phosphodiesterase, acid-like 3A JBrowse link 20 40,779,022 40,800,842 RGD:1624291
RGD:1600115
G Smpdl3b sphingomyelin phosphodiesterase, acid-like 3B JBrowse link 5 150,925,150 150,946,994 RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19576
    cellular process 18361
      cellular metabolic process 10737
        cellular lipid metabolic process 1025
          phospholipid metabolic process 389
            sphingomyelin metabolic process 14
              sphingomyelin biosynthetic process 5
              sphingomyelin catabolic process + 8
Path 2
Term Annotations click to browse term
  biological_process 19576
    metabolic process 11899
      organic substance metabolic process 11297
        lipid metabolic process 1343
          cellular lipid metabolic process 1025
            membrane lipid metabolic process 186
              sphingolipid metabolic process 136
                sphingomyelin metabolic process 14
                  sphingomyelin biosynthetic process 5
                  sphingomyelin catabolic process + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.