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ONTOLOGY REPORT - ANNOTATIONS


Term:sphingomyelin metabolic process
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Accession:GO:0006684 term browser browse the term
Definition:The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine.
Synonyms:exact_synonym: sphingomyelin metabolism


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sphingomyelin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 JBrowse link NW_004936594 3,855,071 3,864,034 RGD:9068941
G Smpd1 sphingomyelin phosphodiesterase 1 JBrowse link NW_004936842 448,315 452,557 RGD:9068941
G Smpd2 sphingomyelin phosphodiesterase 2 JBrowse link NW_004936564 5,565,205 5,568,474 RGD:9068941
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link NW_004936475 18,667,563 18,755,132 RGD:9068941
positive regulation of sphingomyelin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 JBrowse link NW_004936594 3,855,071 3,864,034 RGD:9068941
G Prkcd protein kinase C delta JBrowse link NW_004936473 3,892,625 3,923,467 RGD:9068941
sphingomyelin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pemt phosphatidylethanolamine N-methyltransferase JBrowse link NW_004936741 1,131,792 1,207,460 RGD:9068941
G Samd8 sterile alpha motif domain containing 8 JBrowse link NW_004936521 4,170,016 4,229,877 RGD:9068941
G Sgms1 sphingomyelin synthase 1 JBrowse link NW_004936735 1,702,754 1,984,141 RGD:9068941
G Sgms2 sphingomyelin synthase 2 JBrowse link NW_004936818 687,695 726,123 RGD:9068941
G Sptlc1 serine palmitoyltransferase long chain base subunit 1 JBrowse link NW_004936796 886,946 948,254 RGD:9068941
G Sptlc2 serine palmitoyltransferase long chain base subunit 2 JBrowse link NW_004936488 6,313,189 6,404,425 RGD:9068941
sphingomyelin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 JBrowse link NW_004936594 3,855,071 3,864,034 RGD:9068941
G Smpd1 sphingomyelin phosphodiesterase 1 JBrowse link NW_004936842 448,315 452,557 RGD:9068941
G Smpd2 sphingomyelin phosphodiesterase 2 JBrowse link NW_004936564 5,565,205 5,568,474 RGD:9068941
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link NW_004936475 18,667,563 18,755,132 RGD:9068941
G Smpd4 sphingomyelin phosphodiesterase 4 JBrowse link NW_004936619 2,647,880 2,676,371 RGD:9068941
G Smpdl3a sphingomyelin phosphodiesterase acid like 3A JBrowse link NW_004936802 1,070,919 1,089,222 RGD:9068941
G Smpdl3b sphingomyelin phosphodiesterase acid like 3B JBrowse link NW_004936474 12,158,628 12,179,993 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14835
    cellular process 14230
      cellular metabolic process 9544
        cellular lipid metabolic process 982
          phospholipid metabolic process 429
            sphingomyelin metabolic process 14
              sphingomyelin biosynthetic process 6
              sphingomyelin catabolic process + 8
Path 2
Term Annotations click to browse term
  biological_process 14835
    metabolic process 10258
      organic substance metabolic process 9758
        lipid metabolic process 1283
          cellular lipid metabolic process 982
            membrane lipid metabolic process 203
              sphingolipid metabolic process 157
                sphingomyelin metabolic process 14
                  sphingomyelin biosynthetic process 6
                  sphingomyelin catabolic process + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.