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ONTOLOGY REPORT - ANNOTATIONS


Term:steroid biosynthetic process
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Accession:GO:0006694 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.
Synonyms:exact_synonym: steroid anabolism;   steroid biosynthesis;   steroid formation;   steroid synthesis;   steroidogenesis
 xref: MIPS_funcat:01.06.01.07.11;   Wikipedia:Steroid_metabolisms#Steroid_biosynthesis


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steroid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acbd3 acyl-CoA binding domain containing 3 JBrowse link 13 99,004,942 99,035,520 RGD:1600115
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 JBrowse link 8 62,798,317 62,809,848 RGD:1624270
RGD:1599700
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 RGD:1624284
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 JBrowse link 1 266,422,127 266,429,947 RGD:1298833
RGD:1298835
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:1600115
G Cyp51 cytochrome P450, family 51 JBrowse link 4 27,175,564 27,194,018 RGD:1624291
G Dbi diazepam binding inhibitor, acyl-CoA binding protein JBrowse link 13 36,147,667 36,156,076 RGD:728881
G Dhrs11 dehydrogenase/reductase 11 JBrowse link 10 72,144,042 72,153,496 RGD:1624291
G Fdx1 ferredoxin 1 JBrowse link 8 56,373,729 56,393,199 RGD:1600115
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 JBrowse link 14 7,054,724 7,104,567 RGD:1600115
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 JBrowse link 17 1,579,319 1,610,745 RGD:727276
RGD:13792537
RGD:2326078
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 RGD:13792537
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 JBrowse link 2 200,712,895 200,722,429 RGD:1624291
RGD:13792537
G Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 JBrowse link 2 200,756,557 200,762,492 RGD:1600115
RGD:13792537
G Hsd3b5 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 JBrowse link 2 200,615,910 200,633,317 RGD:1298957
RGD:13792537
RGD:1600115
RGD:1624284
G Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 JBrowse link 1 199,248,084 199,251,745 RGD:1600115
G LOC108348086 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 4 JBrowse link 2 202,341,415 202,350,893 RGD:13792537
G Lss lanosterol synthase JBrowse link 20 12,844,522 12,870,474 RGD:1624291
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 JBrowse link X 54,734,385 54,738,513 RGD:1624291
RGD:1600115
G Scarb1 scavenger receptor class B, member 1 JBrowse link 12 36,694,952 36,761,445 RGD:1304216
RGD:1304382
RGD:1304245
RGD:1304217
G Scp2 sterol carrier protein 2 JBrowse link 5 127,647,934 127,735,703 RGD:1624291
RGD:13792537
G Scp2d1 SCP2 sterol-binding domain containing 1 JBrowse link 3 138,973,171 138,975,624 RGD:13792537
G Sdr42e1 short chain dehydrogenase/reductase family 42E, member 1 JBrowse link 19 50,207,960 50,220,455 RGD:1600115
G Srd5a1 steroid 5 alpha-reductase 1 JBrowse link 1 36,320,504 36,354,694 RGD:2326071
RGD:13792537
G Srd5a2 steroid 5 alpha-reductase 2 JBrowse link 6 25,279,635 25,315,501 RGD:729939
RGD:13792537
RGD:1624291
RGD:2326072
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:634518
RGD:13792537
G Tecr trans-2,3-enoyl-CoA reductase JBrowse link 19 24,705,478 24,732,024 RGD:1600115
G Timp1 TIMP metallopeptidase inhibitor 1 JBrowse link X 1,364,771 1,369,451 RGD:1600115
G Tspo translocator protein JBrowse link 7 124,460,358 124,470,610 RGD:2317176
aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna1h calcium voltage-gated channel subunit alpha1 H JBrowse link 10 14,730,932 14,789,201 RGD:4891166
RGD:1600115
RGD:1624291
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 RGD:4891166
RGD:13792537
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 JBrowse link 7 116,248,759 116,255,205 RGD:727991
RGD:13792537
RGD:1624291
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 JBrowse link 7 116,155,928 116,161,781 RGD:1624291
androgen biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 JBrowse link 1 266,422,127 266,429,947 RGD:1298833
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 JBrowse link 19 50,246,404 50,317,892 RGD:728619
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 JBrowse link 2 200,712,895 200,722,429 RGD:632871
G Med1 mediator complex subunit 1 JBrowse link 10 86,101,560 86,145,271 RGD:1624291
RGD:1600115
G Scarb1 scavenger receptor class B, member 1 JBrowse link 12 36,694,952 36,761,445 RGD:1304382
G Srd5a1 steroid 5 alpha-reductase 1 JBrowse link 1 36,320,504 36,354,694 RGD:4891962
RGD:1624291
G Srd5a2 steroid 5 alpha-reductase 2 JBrowse link 6 25,279,635 25,315,501 RGD:4891962
RGD:1624291
bile acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1d1 aldo-keto reductase family 1, member D1 JBrowse link 4 65,110,706 65,143,930 RGD:1624291
RGD:1600115
G Amacr alpha-methylacyl-CoA racemase JBrowse link 2 60,949,276 60,961,342 RGD:704372
RGD:1600115
G Baat bile acid CoA:amino acid N-acyltransferase JBrowse link 5 64,768,397 64,777,368 RGD:1624291
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 JBrowse link 9 81,968,285 81,998,213 RGD:1600115
RGD:1624291
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 JBrowse link 9 19,804,079 19,880,346 RGD:1624291
RGD:13792537
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 JBrowse link 5 19,358,734 19,368,431 RGD:70535
RGD:13792537
RGD:1624291
RGD:70534
RGD:1600115
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 JBrowse link 2 102,701,903 102,871,257 RGD:1298868
RGD:13792537
RGD:1624291
RGD:1600115
G Hnf1a HNF1 homeobox A JBrowse link 12 47,407,811 47,433,342 RGD:1624291
G Pex2 peroxisomal biogenesis factor 2 JBrowse link 2 98,251,756 98,269,185 RGD:1624291
G Slc27a2 solute carrier family 27 member 2 JBrowse link 3 119,014,620 119,052,531 RGD:1600115
RGD:13792537
RGD:1624291
G Slc27a5 solute carrier family 27 member 5 JBrowse link 1 65,576,599 65,587,192 RGD:1624291
RGD:13792537
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:1600081
brassinosteroid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dhcr7 7-dehydrocholesterol reductase JBrowse link 1 217,018,916 217,034,890 RGD:13792537
C21-steroid hormone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 JBrowse link 8 62,798,317 62,809,848 RGD:4891164
RGD:13792537
RGD:1624291
RGD:1600115
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 RGD:13792537
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 JBrowse link 7 116,248,759 116,255,205 RGD:727991
RGD:13792537
RGD:1624291
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 JBrowse link 7 116,155,928 116,161,781 RGD:1624291
G Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 JBrowse link 20 4,486,213 4,489,358 RGD:1298842
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 JBrowse link 9 81,968,285 81,998,213 RGD:1600115
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 JBrowse link 2 200,712,895 200,722,429 RGD:632871
calcitriol biosynthetic process from calciol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 JBrowse link 9 81,968,285 81,998,213 RGD:1600115
RGD:1624291
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 JBrowse link 7 70,333,150 70,340,006 RGD:1624291
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 JBrowse link 1 184,060,521 184,106,604 RGD:1624291
cholesterol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acat2 acetyl-CoA acetyltransferase 2 JBrowse link 1 47,972,399 47,992,654 RGD:2326086
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:1624291
RGD:13792537
G Apoa4 apolipoprotein A4 JBrowse link 8 50,536,983 50,539,371 RGD:13792537
G Apoa5 apolipoprotein A5 JBrowse link 8 50,559,079 50,561,720 RGD:13792537
G Ces1d carboxylesterase 1D JBrowse link 19 15,195,514 15,239,827 RGD:1624291
G Cftr CF transmembrane conductance regulator JBrowse link 4 42,693,263 42,860,679 RGD:1624291
RGD:1600115
G Cyb5r3 cytochrome b5 reductase 3 JBrowse link 7 124,024,003 124,041,564 RGD:1600115
G Dhcr24 24-dehydrocholesterol reductase JBrowse link 5 126,164,708 126,188,926 RGD:1624291
RGD:1600115
G Dhcr7 7-dehydrocholesterol reductase JBrowse link 1 217,018,916 217,034,890 RGD:625561
RGD:13792537
RGD:1624291
RGD:1600115
RGD:2316918
RGD:2316916
RGD:632010
G Ebp EBP, cholestenol delta-isomerase JBrowse link X 15,049,394 15,055,782 RGD:628445
RGD:13792537
RGD:1624291
RGD:1600115
G Fdft1 farnesyl diphosphate farnesyl transferase 1 JBrowse link 15 46,339,248 46,367,302 RGD:728402
RGD:13792537
RGD:1626611
G Fdps farnesyl diphosphate synthase JBrowse link 2 188,403,595 188,413,219 RGD:728501
G G6pd glucose-6-phosphate dehydrogenase JBrowse link X 156,274,800 156,293,935 RGD:1624291
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 27,480,224 27,500,654 RGD:1300058
RGD:1624291
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 JBrowse link 2 52,427,351 52,445,082 RGD:1600115
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 JBrowse link 2 200,452,623 200,480,785 RGD:1600115
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 JBrowse link 13 88,288,116 88,308,019 RGD:1624291
RGD:13792537
RGD:1600115
G Idi1 isopentenyl-diphosphate delta isomerase 1 JBrowse link 17 57,976,266 57,984,036 RGD:729078
G Insig1 insulin induced gene 1 JBrowse link 4 342,302 350,515 RGD:1624291
G Insig2 insulin induced gene 2 JBrowse link 13 37,264,818 37,292,718 RGD:1624291
G Lbr lamin B receptor JBrowse link 13 100,431,390 100,450,209 RGD:1600115
RGD:1624291
G Lss lanosterol synthase JBrowse link 20 12,844,522 12,870,474 RGD:1626611
RGD:13792537
RGD:1600115
RGD:1624291
RGD:2316919
G Mvd mevalonate diphosphate decarboxylase JBrowse link 19 55,258,910 55,268,933 RGD:729305
RGD:1600115
G Mvk mevalonate kinase JBrowse link 12 47,904,266 47,920,457 RGD:728935
RGD:1600115
RGD:13792537
RGD:1624291
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 JBrowse link 14 86,345,946 86,560,694 RGD:1624291
G Nsdhl NAD(P) dependent steroid dehydrogenase-like JBrowse link X 152,933,118 152,964,399 RGD:1600115
G Pmvk phosphomevalonate kinase JBrowse link 2 188,784,329 188,793,890 RGD:8553625
RGD:13792537
RGD:1624291
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 JBrowse link 2 54,857,688 54,893,404 RGD:1600115
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 JBrowse link 5 124,568,845 124,642,569 RGD:1600115
G Tm7sf2 transmembrane 7 superfamily member 2 JBrowse link 1 221,426,017 221,430,340 RGD:13825441
RGD:1624291
cholesterol biosynthetic process via 24,25-dihydrolanosterol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp51 cytochrome P450, family 51 JBrowse link 4 27,175,564 27,194,018 RGD:2316902
RGD:13792537
cholesterol biosynthetic process via lathosterol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sc5d sterol-C5-desaturase JBrowse link 8 46,525,406 46,537,014 RGD:2316911
RGD:13792537
cortisol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna1h calcium voltage-gated channel subunit alpha1 H JBrowse link 10 14,730,932 14,789,201 RGD:4891166
RGD:1600115
RGD:1624291
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 RGD:4891166
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 JBrowse link 7 116,248,759 116,255,205 RGD:1624291
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 JBrowse link 7 116,155,928 116,161,781 RGD:1624291
ergosterol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 JBrowse link 1 256,382,861 256,386,729 RGD:13792537
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 JBrowse link 4 116,261,796 116,278,615 RGD:13792537
G Cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 JBrowse link 1 256,369,410 256,380,649 RGD:13792537
G Erg28 ergosterol biosynthesis 28 homolog JBrowse link 6 109,683,252 109,692,218 RGD:13792537
G Fdft1 farnesyl diphosphate farnesyl transferase 1 JBrowse link 15 46,339,248 46,367,302 RGD:1600115
estrogen biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:4891164
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 JBrowse link 10 88,987,558 88,989,758 RGD:728619
RGD:1600115
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 JBrowse link 3 82,924,699 83,048,465 RGD:1600115
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 JBrowse link 19 50,246,404 50,317,892 RGD:728619
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 JBrowse link 13 88,288,116 88,308,019 RGD:1600115
G Hsd17b8 hydroxysteroid (17-beta) dehydrogenase 8 JBrowse link 20 3,817,212 3,819,316 RGD:1600115
RGD:13792537
RGD:1624291
G Rdh8 retinol dehydrogenase 8 JBrowse link 8 21,835,065 21,842,374 RGD:1600115
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:1600078
glucocorticoid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:1624291
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 JBrowse link 8 62,798,317 62,809,848 RGD:13792537
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 RGD:4891164
RGD:13792537
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 JBrowse link 7 116,248,759 116,255,205 RGD:727991
RGD:13792537
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 JBrowse link 7 116,155,928 116,161,781 RGD:1624291
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 JBrowse link 1 266,422,127 266,429,947 RGD:1624291
RGD:1600115
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 JBrowse link 13 111,946,626 111,996,536 RGD:1625060
mineralocorticoid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 JBrowse link 20 4,486,213 4,489,358 RGD:4891164
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
RGD:1600115
G Bmp5 bone morphogenetic protein 5 JBrowse link 8 82,669,466 82,950,273 RGD:1624291
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 JBrowse link 1 176,940,424 176,983,076 RGD:1624291
G Rest RE1-silencing transcription factor JBrowse link 14 33,131,985 33,152,019 RGD:4891166
RGD:1624291
RGD:1600115
negative regulation of androgen biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1600115
RGD:1624291
negative regulation of bile acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf19 fibroblast growth factor 19 JBrowse link 1 218,058,405 218,061,693 RGD:1624291
G Malrd1 MAM and LDL receptor class A domain containing 1 JBrowse link 17 82,430,836 83,156,696 RGD:1624291
G Prox1 prospero homeobox 1 JBrowse link 13 108,382,536 108,444,107 RGD:1624291
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 JBrowse link 7 70,333,150 70,340,006 RGD:1624291
G Gfi1 growth factor independent 1 transcriptional repressor JBrowse link 14 3,058,035 3,073,332 RGD:1624291
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:1624291
RGD:1600115
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:1624291
RGD:1600115
RGD:10059686
G Erlin1 ER lipid raft associated 1 JBrowse link 1 263,810,439 263,845,762 RGD:1624291
G Erlin2 ER lipid raft associated 2 JBrowse link 16 69,179,005 69,195,452 RGD:1624291
G Idi2 isopentenyl-diphosphate delta isomerase 2 JBrowse link 17 63,107,152 63,107,469 RGD:1624291
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:1624291
RGD:1600115
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
RGD:1600115
G Bmp5 bone morphogenetic protein 5 JBrowse link 8 82,669,466 82,950,273 RGD:1624291
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 JBrowse link 1 176,940,424 176,983,076 RGD:1624291
G Rest RE1-silencing transcription factor JBrowse link 14 33,131,985 33,152,019 RGD:4891166
RGD:1624291
RGD:1600115
negative regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 JBrowse link 2 204,003,742 204,032,023 RGD:1624291
negative regulation of steroid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
G Bmp5 bone morphogenetic protein 5 JBrowse link 8 82,669,466 82,950,273 RGD:1624291
G Hrh1 histamine receptor H 1 JBrowse link 4 146,374,596 146,458,148 RGD:2316921
G Insig1 insulin induced gene 1 JBrowse link 4 342,302 350,515 RGD:1624291
G Insig2 insulin induced gene 2 JBrowse link 13 37,264,818 37,292,718 RGD:1624291
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1624291
negative regulation of steroid hormone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pde8b phosphodiesterase 8B JBrowse link 2 24,718,548 24,955,533 RGD:1624291
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dkkl1 dickkopf like acrosomal protein 1 JBrowse link 1 101,205,426 101,210,675 RGD:1624291
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1600115
RGD:1624291
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Snai1 snail family transcriptional repressor 1 JBrowse link 3 164,274,710 164,279,199 RGD:1624291
G Snai2 snail family transcriptional repressor 2 JBrowse link 11 90,404,421 90,406,730 RGD:1624291
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp6 bone morphogenetic protein 6 JBrowse link 17 26,955,142 27,112,820 RGD:1624291
G Dab2 DAB adaptor protein 2 JBrowse link 2 55,747,353 55,768,848 RGD:7243836
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1600115
RGD:1624291
positive regulation of bile acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 JBrowse link 10 86,683,875 86,690,815 RGD:1600115
RGD:1624291
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:1624291
G Stard4 StAR-related lipid transfer domain containing 4 JBrowse link 18 25,982,210 25,997,555 RGD:1624291
positive regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1600115
RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcg1 ATP binding cassette subfamily G member 1 JBrowse link 20 9,743,269 9,842,735 RGD:1624291
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 JBrowse link 5 19,358,734 19,368,431 RGD:13792517
G Fdps farnesyl diphosphate synthase JBrowse link 2 188,403,595 188,413,219 RGD:2316295
G Fgf1 fibroblast growth factor 1 JBrowse link 18 32,273,830 32,359,831 RGD:1624291
RGD:1600115
G Por cytochrome p450 oxidoreductase JBrowse link 12 23,998,411 24,017,063 RGD:2316785
G Scp2 sterol carrier protein 2 JBrowse link 5 127,647,934 127,735,703 RGD:9850260
G Sec14l2 SEC14-like lipid binding 2 JBrowse link 14 84,335,594 84,360,354 RGD:727312
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 10 46,570,996 46,593,021 RGD:1624291
positive regulation of cortisol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1600115
RGD:1624291
positive regulation of progesterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ppargc1a PPARG coactivator 1 alpha JBrowse link 14 63,095,291 63,190,688 RGD:10059648
positive regulation of steroid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora2b adenosine A2B receptor JBrowse link 10 48,569,563 48,586,366 RGD:2316120
G Cga glycoprotein hormones, alpha polypeptide JBrowse link 5 50,362,491 50,393,368 RGD:1600115
RGD:13792537
RGD:1624291
G Fshb follicle stimulating hormone subunit beta JBrowse link 3 98,088,321 98,092,131 RGD:1624291
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:2311095
G Scp2 sterol carrier protein 2 JBrowse link 5 127,647,934 127,735,703 RGD:8554045
RGD:9999179
positive regulation of steroid hormone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 JBrowse link 1 266,422,127 266,429,947 RGD:4888510
G Gh1 growth hormone 1 JBrowse link 10 94,486,204 94,488,181 RGD:1600072
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1600072
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:1600072
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:1600072
G Por cytochrome p450 oxidoreductase JBrowse link 12 23,998,411 24,017,063 RGD:4889602
positive regulation of vitamin D biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
progesterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 RGD:1625116
G Scp2 sterol carrier protein 2 JBrowse link 5 127,647,934 127,735,703 RGD:1624291
G Stard3 StAR-related lipid transfer domain containing 3 JBrowse link 10 86,313,430 86,335,868 RGD:1624291
regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clcn2 chloride voltage-gated channel 2 JBrowse link 11 82,862,664 82,876,165 RGD:1600115
RGD:1624291
G LOC108348101 chloride channel protein 2 JBrowse link 11 83,883,428 83,897,396 RGD:1600115
regulation of bile acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 JBrowse link 5 19,358,734 19,368,431 RGD:70534
RGD:1624291
G Fgfr4 fibroblast growth factor receptor 4 JBrowse link 17 9,990,072 10,004,339 RGD:1624291
RGD:13792537
RGD:1600115
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:1624291
RGD:1600115
regulation of cholesterol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca2 ATP binding cassette subfamily A member 2 JBrowse link 3 2,648,787 2,668,770 RGD:1624291
G Apob apolipoprotein B JBrowse link 6 33,176,826 33,216,381 RGD:1624291
G Cyp51 cytochrome P450, family 51 JBrowse link 4 27,175,564 27,194,018 RGD:1298863
G Dhcr7 7-dehydrocholesterol reductase JBrowse link 1 217,018,916 217,034,890 RGD:632010
G Mvk mevalonate kinase JBrowse link 12 47,904,266 47,920,457 RGD:728935
G Pex2 peroxisomal biogenesis factor 2 JBrowse link 2 98,251,756 98,269,185 RGD:1624291
G Scap SREBF chaperone JBrowse link 8 118,551,869 118,628,650 RGD:1624291
regulation of cortisol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dgkq diacylglycerol kinase, theta JBrowse link 14 2,069,409 2,083,370 RGD:1624291
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) JBrowse link 5 166,994,683 167,030,441 RGD:1624291
regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:1624291
regulation of progesterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dgkq diacylglycerol kinase, theta JBrowse link 14 2,069,409 2,083,370 RGD:1624291
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:1600115
RGD:1624291
regulation of steroid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:2303525
G Asah1 N-acylsphingosine amidohydrolase 1 JBrowse link 16 53,998,604 54,030,006 RGD:1600115
RGD:1624291
G Ddx20 DEAD-box helicase 20 JBrowse link 2 208,144,142 208,154,764 RGD:1624291
G Dhh desert hedgehog signaling molecule JBrowse link 7 140,575,288 140,580,783 RGD:1624291
G Hsd3b5 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 JBrowse link 2 200,615,910 200,633,317 RGD:2303525
G Igfbp7 insulin-like growth factor binding protein 7 JBrowse link 14 33,010,300 33,070,193 RGD:1626541
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:1624291
G Lhcgr luteinizing hormone/choriogonadotropin receptor JBrowse link 6 12,493,182 12,554,482 RGD:1600071
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 JBrowse link X 54,734,385 54,738,513 RGD:1357210
G Sf1 splicing factor 1 JBrowse link 1 221,735,512 221,749,216 RGD:1624291
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:1624291
RGD:13792537
G Tspo translocator protein JBrowse link 7 124,460,358 124,470,610 RGD:2317173
regulation of steroid hormone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lhcgr luteinizing hormone/choriogonadotropin receptor JBrowse link 6 12,493,182 12,554,482 RGD:1624291
RGD:1600115
regulation of testosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:1624291
G Cmtm2a CKLF-like MARVEL transmembrane domain containing 2A JBrowse link 19 880,024 887,144 RGD:1624291
G Prkg1 protein kinase cGMP-dependent 1 JBrowse link 1 248,982,039 250,300,952 RGD:7775068
sterol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07021955.1 RGD:13792537
G Ch25h cholesterol 25-hydroxylase JBrowse link 1 252,807,062 252,811,409 RGD:13792537
G Cyb5r1 cytochrome b5 reductase 1 JBrowse link 13 51,229,697 51,236,447 RGD:1600115
G Cyb5r2 cytochrome b5 reductase 2 JBrowse link 1 171,971,424 171,981,586 RGD:1600115
G Cyp51 cytochrome P450, family 51 JBrowse link 4 27,175,564 27,194,018 RGD:13792537
G Dhcr7 7-dehydrocholesterol reductase JBrowse link 1 217,018,916 217,034,890 RGD:1624291
RGD:13792537
G Ebp EBP, cholestenol delta-isomerase JBrowse link X 15,049,394 15,055,782 RGD:628445
RGD:13792537
RGD:1624291
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 27,480,224 27,500,654 RGD:13792537
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 JBrowse link 2 200,452,623 200,480,785 RGD:1600115
G Insig1 insulin induced gene 1 JBrowse link 4 342,302 350,515 RGD:1624291
G Insig2 insulin induced gene 2 JBrowse link 13 37,264,818 37,292,718 RGD:1624291
G Lbr lamin B receptor JBrowse link 13 100,431,390 100,450,209 RGD:13792537
G Msmo1 methylsterol monooxygenase 1 JBrowse link 16 26,859,441 26,875,880 RGD:13792537
G Pmvk phosphomevalonate kinase JBrowse link 2 188,784,329 188,793,890 RGD:1624291
G Sc5d sterol-C5-desaturase JBrowse link 8 46,525,406 46,537,014 RGD:13792537
G Sqle squalene epoxidase JBrowse link 7 99,609,929 99,624,803 RGD:1600115
RGD:13792537
RGD:1624291
G Tm7sf2 transmembrane 7 superfamily member 2 JBrowse link 1 221,426,017 221,430,340 RGD:13792537
testosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:1624291
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 JBrowse link 8 62,798,317 62,809,848 RGD:4145609
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:1624291
RGD:1600115
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 JBrowse link 10 88,987,558 88,989,758 RGD:728619
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 JBrowse link 17 1,579,319 1,610,745 RGD:1600115
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 RGD:4889544
G Srd5a2 steroid 5 alpha-reductase 2 JBrowse link 6 25,279,635 25,315,501 RGD:1624291
RGD:1600115
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:4145609

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    metabolic process 11555
      primary metabolic process 10411
        lipid metabolic process 1300
          steroid metabolic process 306
            steroid biosynthetic process 160
              (17Z)-protosta-17(20),24-dien-3beta-ol biosynthetic process 0
              bile acid biosynthetic process + 19
              brexanolone biosynthetic process 0
              ergosteryl 3-beta-D-glucoside biosynthetic process 0
              helvolic acid biosynthetic process + 0
              negative regulation of steroid biosynthetic process + 24
              phytosteroid biosynthetic process + 6
              positive regulation of steroid biosynthetic process + 27
              regulation of steroid biosynthetic process + 79
              steroid hormone biosynthetic process + 49
              sterol biosynthetic process + 58
              vitamin D biosynthetic process + 11
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.