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ONTOLOGY REPORT - ANNOTATIONS


Term:bile acid biosynthetic process
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Accession:GO:0006699 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile.
Synonyms:exact_synonym: bile acid anabolism;   bile acid biosynthesis;   bile acid formation;   bile acid synthesis


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bile acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1d1 aldo-keto reductase family 1, member D1 JBrowse link 4 65,110,706 65,143,930 RGD:1624291
RGD:1600115
G Amacr alpha-methylacyl-CoA racemase JBrowse link 2 60,949,276 60,961,342 RGD:704372
RGD:1600115
G Baat bile acid CoA:amino acid N-acyltransferase JBrowse link 5 64,768,397 64,777,368 RGD:1624291
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 JBrowse link 9 81,968,285 81,998,213 RGD:1600115
RGD:1624291
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 JBrowse link 9 19,804,079 19,880,346 RGD:1624291
RGD:13792537
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 JBrowse link 5 19,358,734 19,368,431 RGD:70535
RGD:13792537
RGD:1624291
RGD:70534
RGD:1600115
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 JBrowse link 2 102,701,903 102,871,257 RGD:1298868
RGD:13792537
RGD:1624291
RGD:1600115
G Hnf1a HNF1 homeobox A JBrowse link 12 47,407,811 47,433,342 RGD:1624291
G Pex2 peroxisomal biogenesis factor 2 JBrowse link 2 98,251,756 98,269,185 RGD:1624291
G Slc27a2 solute carrier family 27 member 2 JBrowse link 3 119,014,620 119,052,531 RGD:1600115
RGD:13792537
RGD:1624291
G Slc27a5 solute carrier family 27 member 5 JBrowse link 1 65,576,599 65,587,192 RGD:1624291
RGD:13792537
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:1600081
negative regulation of bile acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf19 fibroblast growth factor 19 JBrowse link 1 218,058,405 218,061,693 RGD:1624291
G Malrd1 MAM and LDL receptor class A domain containing 1 JBrowse link 17 82,430,836 83,156,696 RGD:1624291
G Prox1 prospero homeobox 1 JBrowse link 13 108,382,536 108,444,107 RGD:1624291
positive regulation of bile acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 JBrowse link 10 86,683,875 86,690,815 RGD:1600115
RGD:1624291
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:1624291
G Stard4 StAR-related lipid transfer domain containing 4 JBrowse link 18 25,982,210 25,997,555 RGD:1624291
regulation of bile acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 JBrowse link 5 19,358,734 19,368,431 RGD:70534
RGD:1624291
G Fgfr4 fibroblast growth factor receptor 4 JBrowse link 17 9,990,072 10,004,339 RGD:1624291
RGD:13792537
RGD:1600115
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11638
      organic substance metabolic process 11027
        organic hydroxy compound metabolic process 528
          bile acid metabolic process 33
            bile acid biosynthetic process 19
              negative regulation of bile acid biosynthetic process 3
              positive regulation of bile acid biosynthetic process 3
              regulation of bile acid biosynthetic process + 9
Path 2
Term Annotations click to browse term
  biological_process 19439
    cellular process 18178
      cellular metabolic process 10639
        organic acid metabolic process 1043
          oxoacid metabolic process 1016
            carboxylic acid metabolic process 972
              carboxylic acid biosynthetic process 294
                monocarboxylic acid biosynthetic process 189
                  bile acid biosynthetic process 19
                    negative regulation of bile acid biosynthetic process 3
                    positive regulation of bile acid biosynthetic process 3
                    regulation of bile acid biosynthetic process + 9
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.