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ONTOLOGY REPORT - ANNOTATIONS


Term:C21-steroid hormone biosynthetic process
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Accession:GO:0006700 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.
Synonyms:exact_synonym: C21-steroid hormone anabolism;   C21-steroid hormone biosynthesis;   C21-steroid hormone formation;   C21-steroid hormone synthesis


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C21-steroid hormone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKR1B1 aldo-keto reductase family 1 member B JBrowse link 7 138,907,448 138,924,317 RGD:9068941
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 JBrowse link 15 72,901,274 72,931,614 RGD:9068941
G FDX1 ferredoxin 1 JBrowse link 11 109,158,419 109,190,869 RGD:9068941
G FDX2 ferredoxin 2 JBrowse link 19 10,520,072 10,532,163 RGD:9068941
G FDXR ferredoxin reductase JBrowse link 17 74,364,343 74,374,852 RGD:9068941
G STAR steroidogenic acute regulatory protein JBrowse link 8 34,622,577 34,629,912 RGD:9068941
G STARD3 StAR related lipid transfer domain containing 3 JBrowse link 17 17,841,500 17,868,535 RGD:9068941
G STARD3NL STARD3 N-terminal like JBrowse link 7 39,032,317 39,084,789 RGD:9068941
G TSPO translocator protein JBrowse link 22 42,233,186 42,244,930 RGD:9068941
G TSPOAP1 TSPO associated protein 1 JBrowse link 17 57,232,244 57,259,669 RGD:9068941
aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CACNA1H calcium voltage-gated channel subunit alpha1 H JBrowse link 16 1,195,991 1,222,917 RGD:9068941
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BMP2 bone morphogenetic protein 2 JBrowse link 20 6,546,173 6,558,627 RGD:9068941
G BMP5 bone morphogenetic protein 5 JBrowse link 6 56,936,871 57,058,801 RGD:9068941
G DKK3 dickkopf WNT signaling pathway inhibitor 3 JBrowse link 11 11,824,955 11,871,139 RGD:9068941
G REST RE1 silencing transcription factor JBrowse link 4 73,556,780 73,582,419 RGD:9068941
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BMP6 bone morphogenetic protein 6 JBrowse link 6 7,848,255 8,002,030 RGD:9068941
G WNT4 Wnt family member 4 JBrowse link 1 22,252,344 22,264,858 RGD:9068941
positive regulation of progesterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADM adrenomedullin JBrowse link 11 10,165,423 10,167,842 RGD:9068941
G PPARGC1A PPARG coactivator 1 alpha JBrowse link 4 23,483,377 24,160,574 RGD:9068941
progesterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FSHB follicle stimulating hormone subunit beta JBrowse link 11 30,095,759 30,100,012 RGD:9068941
G LHB luteinizing hormone subunit beta JBrowse link 19 54,738,139 54,739,424 RGD:9068941
G SCP2 sterol carrier protein 2 JBrowse link 1 53,797,256 53,924,939 RGD:9068941
G STARD3 StAR related lipid transfer domain containing 3 JBrowse link 17 17,841,500 17,868,535 RGD:9068941
regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CLCN2 chloride voltage-gated channel 2 JBrowse link 3 189,865,627 189,881,049 RGD:9068941
regulation of progesterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DGKQ diacylglycerol kinase theta JBrowse link 4 993,261 1,009,414 RGD:9068941
G EGR1 early growth response 1 JBrowse link 5 139,975,635 139,979,259 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15702
    cellular process 14997
      cellular metabolic process 9894
        cellular biosynthetic process 5599
          C21-steroid hormone biosynthetic process 25
            aldosterone biosynthetic process + 8
            progesterone biosynthetic process + 8
Path 2
Term Annotations click to browse term
  biological_process 15702
    metabolic process 10530
      primary metabolic process 9642
        lipid metabolic process 1320
          lipid biosynthetic process 682
            steroid biosynthetic process 187
              steroid hormone biosynthetic process 55
                C21-steroid hormone biosynthetic process 25
                  aldosterone biosynthetic process + 8
                  progesterone biosynthetic process + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.