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ONTOLOGY REPORT - ANNOTATIONS


Term:C21-steroid hormone biosynthetic process
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Accession:GO:0006700 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.
Synonyms:exact_synonym: C21-steroid hormone anabolism;   C21-steroid hormone biosynthesis;   C21-steroid hormone formation;   C21-steroid hormone synthesis


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C21-steroid hormone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 JBrowse link 9 57,998,024 58,027,031 RGD:2290270
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 JBrowse link 15 74,834,892 74,841,643 RGD:2290270
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 JBrowse link 15 74,850,618 74,856,231 RGD:2290270
G Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 JBrowse link 17 34,801,348 34,804,426 RGD:2290270
aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna1h calcium channel, voltage-dependent, T type, alpha 1H subunit JBrowse link 17 25,374,285 25,436,334 RGD:2290270
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 JBrowse link 15 74,834,892 74,841,643 RGD:2290270
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 JBrowse link 15 74,850,618 74,856,231 RGD:2290270
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp2 bone morphogenetic protein 2 JBrowse link 2 133,552,159 133,562,896 RGD:2290270
G Bmp5 bone morphogenetic protein 5 JBrowse link 9 75,775,365 75,900,316 RGD:2290270
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 JBrowse link 7 112,116,019 112,159,482 RGD:2290270
G Rest RE1-silencing transcription factor JBrowse link 5 77,265,494 77,286,432 RGD:2290270
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp6 bone morphogenetic protein 6 JBrowse link 13 38,345,716 38,500,314 RGD:2290270
G Dab2 disabled 2, mitogen-responsive phosphoprotein JBrowse link 15 6,299,788 6,440,715 RGD:2290270
G Wnt4 wingless-type MMTV integration site family, member 4 JBrowse link 4 137,277,635 137,299,501 RGD:2290270
positive regulation of progesterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha JBrowse link 5 51,454,249 52,115,853 RGD:2290270
progesterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Scp2 sterol carrier protein 2, liver JBrowse link 4 108,043,830 108,144,971 RGD:2290270
G Stard3 START domain containing 3 JBrowse link 11 98,358,367 98,381,112 RGD:2290270
regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clcn2 chloride channel, voltage-sensitive 2 JBrowse link 16 20,702,435 20,717,746 RGD:2290270
regulation of progesterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dgkq diacylglycerol kinase, theta JBrowse link 5 108,647,044 108,660,830 RGD:2290270
G Egr1 early growth response 1 JBrowse link 18 34,861,207 34,864,956 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23101
    cellular process 16746
      cellular metabolic process 9566
        cellular biosynthetic process 5088
          C21-steroid hormone biosynthetic process 18
            aldosterone biosynthetic process + 11
            progesterone biosynthetic process + 5
Path 2
Term Annotations click to browse term
  biological_process 23101
    metabolic process 10604
      primary metabolic process 9428
        lipid metabolic process 1279
          lipid biosynthetic process 561
            steroid biosynthetic process 161
              steroid hormone biosynthetic process 43
                C21-steroid hormone biosynthetic process 18
                  aldosterone biosynthetic process + 11
                  progesterone biosynthetic process + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.