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ONTOLOGY REPORT - ANNOTATIONS


Term:C21-steroid hormone biosynthetic process
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Accession:GO:0006700 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.
Synonyms:exact_synonym: C21-steroid hormone anabolism;   C21-steroid hormone biosynthesis;   C21-steroid hormone formation;   C21-steroid hormone synthesis


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C21-steroid hormone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 JBrowse link 8 62,798,317 62,809,848 RGD:4891164
RGD:13792537
RGD:1624291
RGD:1600115
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 RGD:13792537
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 JBrowse link 7 116,248,759 116,255,205 RGD:727991
RGD:13792537
RGD:1624291
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 JBrowse link 7 116,155,928 116,161,781 RGD:1624291
G Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 JBrowse link 20 4,486,213 4,489,358 RGD:1298842
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 JBrowse link 9 81,968,285 81,998,213 RGD:1600115
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 JBrowse link 2 200,712,895 200,722,429 RGD:632871
aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna1h calcium voltage-gated channel subunit alpha1 H JBrowse link 10 14,730,932 14,789,201 RGD:4891166
RGD:1600115
RGD:1624291
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 RGD:4891166
RGD:13792537
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 JBrowse link 7 116,248,759 116,255,205 RGD:727991
RGD:13792537
RGD:1624291
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 JBrowse link 7 116,155,928 116,161,781 RGD:1624291
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
RGD:1600115
G Bmp5 bone morphogenetic protein 5 JBrowse link 8 82,669,466 82,950,273 RGD:1624291
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 JBrowse link 1 176,940,424 176,983,076 RGD:1624291
G Rest RE1-silencing transcription factor JBrowse link 14 33,131,985 33,152,019 RGD:4891166
RGD:1624291
RGD:1600115
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp6 bone morphogenetic protein 6 JBrowse link 17 26,955,142 27,112,820 RGD:1624291
G Dab2 DAB adaptor protein 2 JBrowse link 2 55,747,353 55,768,848 RGD:7243836
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1600115
RGD:1624291
positive regulation of progesterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ppargc1a PPARG coactivator 1 alpha JBrowse link 14 63,095,291 63,190,688 RGD:10059648
progesterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 RGD:1625116
G Scp2 sterol carrier protein 2 JBrowse link 5 127,647,934 127,735,703 RGD:1624291
G Stard3 StAR-related lipid transfer domain containing 3 JBrowse link 10 86,313,430 86,335,868 RGD:1624291
regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clcn2 chloride voltage-gated channel 2 JBrowse link 11 82,862,664 82,876,165 RGD:1600115
RGD:1624291
G LOC108348101 chloride channel protein 2 JBrowse link 11 83,883,428 83,897,396 RGD:1600115
regulation of progesterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dgkq diacylglycerol kinase, theta JBrowse link 14 2,069,409 2,083,370 RGD:1624291
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    cellular process 18179
      cellular metabolic process 10644
        cellular biosynthetic process 5814
          C21-steroid hormone biosynthetic process 23
            aldosterone biosynthetic process + 13
            progesterone biosynthetic process + 6
Path 2
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11641
      primary metabolic process 10482
        lipid metabolic process 1315
          lipid biosynthetic process 572
            steroid biosynthetic process 159
              steroid hormone biosynthetic process 49
                C21-steroid hormone biosynthetic process 23
                  aldosterone biosynthetic process + 13
                  progesterone biosynthetic process + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.