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ONTOLOGY REPORT - ANNOTATIONS


Term:serotonin transport
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Accession:GO:0006837 term browser browse the term
Definition:The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.


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serotonin transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a3 solute carrier family 22 member 3 ISO (MGI:MGI:3805626|PMID:18513366) RGD PMID:18513366 MGI:MGI:3805626 NCBI chr 1:48,433,079...48,521,261
Ensembl chr 1:48,433,079...48,521,256
JBrowse link
G Slc6a4 solute carrier family 6 member 4 TAS
ISO
IDA
IMP
(MGI:MGI:4820706|PMID:19308295)
PMID:11709063
RGD PMID:19308295, PMID:12220705, PMID:11709063, PMID:15994310 MGI:MGI:4820706, RGD:730261, RGD:8553990, RGD:1580635 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463
JBrowse link
negative regulation of serotonin secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule ISO (MGI:MGI:3721168|PMID:12874256) RGD PMID:12874256 MGI:MGI:3721168 NCBI chr10:103,437,978...103,451,170
Ensembl chr10:103,438,303...103,450,947
JBrowse link
G Cnr1 cannabinoid receptor 1 IMP PMID:30217553 CACAO PMID:30217553 RGD:15023474 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Hrh3 histamine receptor H3 IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:15470136, PMID:21873635 RGD:1626430, RGD:13792537 NCBI chr 3:175,474,310...175,479,395
Ensembl chr 3:175,473,078...175,479,395
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B ISO
ISS
(MGI:MGI:1098377|PMID:9349547)
GO_REF:0000024
RGD
UniProt
PMID:9349547 GO_REF:0000024, MGI:MGI:1098377 NCBI chr 8:89,113,984...89,130,830
Ensembl chr 8:89,129,453...89,130,991
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 IMP RGD PMID:15260125 RGD:6480684 NCBI chr 1:254,547,964...254,671,811
Ensembl chr 1:254,547,620...254,671,778
JBrowse link
G Maob monoamine oxidase B IMP RGD PMID:12175458 RGD:2316765 NCBI chr  X:6,430,694...6,533,520
Ensembl chr  X:6,430,594...6,533,534
JBrowse link
negative regulation of serotonin uptake term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpm6b glycoprotein m6b ISO
IBA
ISS
(MGI:MGI:5426133|PMID:18581270)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:18581270, PMID:21873635 GO_REF:0000024, MGI:MGI:5426133, RGD:13792537 NCBI chr  X:29,604,607...29,751,174
Ensembl chr  X:29,607,075...29,648,403
JBrowse link
G Nos1 nitric oxide synthase 1 IEA
ISO
GO_REF:0000107
(MGI:MGI:3710710|PMID:17452640)
Ensembl
RGD
PMID:17452640 GO_REF:0000107, MGI:MGI:3710710 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Slc18a1 solute carrier family 18 member A1 IMP G-protein mediated uptake inhibition RGD PMID:16926160 RGD:5130998 NCBI chr16:22,358,646...22,395,183
Ensembl chr16:22,361,998...22,395,183
JBrowse link
G Snca synuclein alpha ISO (PMID:16882008) RGD PMID:16882008 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
positive regulation of serotonin secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:20655906 RGD:5130946 NCBI chr 4:85,286,371...85,329,374
Ensembl chr 4:85,286,372...85,329,362
JBrowse link
G Lgals3 galectin 3 IDA RGD PMID:8347574 RGD:9685207 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Slc6a4 solute carrier family 6 member 4 IMP RGD PMID:25261262 RGD:11532763 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463
JBrowse link
regulation of serotonin secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone IDA RGD PMID:21947356 RGD:5507821 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO
ISS
(MGI:MGI:1314969|PMID:9826725)
GO_REF:0000024
RGD
UniProt
PMID:9826725 GO_REF:0000024, MGI:MGI:1314969 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
regulation of serotonin uptake term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgb3 integrin subunit beta 3 ISO
ISS
(MGI:MGI:6101340|PMID:29038237)
GO_REF:0000024
RGD
UniProt
PMID:29038237 GO_REF:0000024, MGI:MGI:6101340 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
serotonin secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1a Fc fragment of IgE receptor Ia ISO MGI:MGI:2383982 (MGI:MGI:85068|PMID:9000133), (MGI:MGI:86632|PMID:8252632) RGD PMID:8252632, PMID:9000133 MGI:MGI:85068, MGI:MGI:86632 NCBI chr13:91,727,253...91,737,106
Ensembl chr13:91,730,925...91,737,053
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa ISO (MGI:MGI:78617|PMID:8552190) RGD PMID:8552190 MGI:MGI:78617 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036
JBrowse link
G Syk spleen associated tyrosine kinase ISO MGI:MGI:2384078 (MGI:MGI:85068|PMID:9000133) RGD PMID:9000133 MGI:MGI:85068 NCBI chr17:12,614,311...12,669,568
Ensembl chr17:12,614,311...12,669,573
JBrowse link
serotonin secretion by mast cell term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule ISO (MGI:MGI:3721168|PMID:12874256) RGD PMID:12874256 MGI:MGI:3721168 NCBI chr10:103,437,978...103,451,170
Ensembl chr10:103,438,303...103,450,947
JBrowse link
serotonin secretion by platelet term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc fragment of IgE receptor Ig ISO (MGI:MGI:87668|PMID:9171347) RGD PMID:9171347 MGI:MGI:87668 NCBI chr13:89,601,894...89,606,326
Ensembl chr13:89,601,896...89,606,326
JBrowse link
G P2rx1 purinergic receptor P2X 1 ISO MGI:MGI:2181608 (MGI:MGI:2671726|PMID:12913094) RGD PMID:12913094 MGI:MGI:2671726 NCBI chr10:59,566,268...59,581,328
Ensembl chr10:59,566,223...59,581,325
JBrowse link
G Syk spleen associated tyrosine kinase IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:87668|PMID:9171347)
Ensembl
UniProt
RGD
PMID:9171347 GO_REF:0000024, GO_REF:0000107, MGI:MGI:87668 NCBI chr17:12,614,311...12,669,568
Ensembl chr17:12,614,311...12,669,573
JBrowse link
serotonin secretion, neurotransmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Xbp1 X-box binding protein 1 IDA RGD PMID:16889758 RGD:2326003 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
serotonin uptake term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc18a1 solute carrier family 18 member A1 IDA RGD PMID:19008227 RGD:5131091 NCBI chr16:22,358,646...22,395,183
Ensembl chr16:22,361,998...22,395,183
JBrowse link
G Slc18a2 solute carrier family 18 member A2 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:280,397,831...280,457,968
Ensembl chr 1:280,423,079...280,457,148
JBrowse link
G Slc22a1 solute carrier family 22 member 1 ISO
IEA
(PMID:24688079)
GO_REF:0000107
RGD
Ensembl
PMID:24688079 GO_REF:0000107 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655
JBrowse link
G Slc22a2 solute carrier family 22 member 2 ISO
IEA
(PMID:9687576)
GO_REF:0000107
RGD
Ensembl
PMID:9687576 GO_REF:0000107 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc22a3 solute carrier family 22 member 3 ISO
IEA
(PMID:20858707)
GO_REF:0000107
RGD
Ensembl
PMID:20858707 GO_REF:0000107 NCBI chr 1:48,433,079...48,521,261
Ensembl chr 1:48,433,079...48,521,256
JBrowse link
G Slc29a4 solute carrier family 29 member 4 ISO
IEA
(PMID:20858707)
GO_REF:0000107
(MGI:MGI:5484979|PMID:23255610), (MGI:MGI:6436398|PMID:20858707)
RGD
Ensembl
PMID:20858707, PMID:23255610 GO_REF:0000107, MGI:MGI:5484979, MGI:MGI:6436398 NCBI chr12:13,914,114...13,924,511
Ensembl chr12:13,914,114...13,924,531
JBrowse link
G Slc6a4 solute carrier family 6 member 4 IMP
ISO
IDA
IBA
(MGI:MGI:2178281|PMID:9547354), (MGI:MGI:3710710|PMID:17452640), (MGI:MGI:6436398|PMID:20858707)
PMID:10716733
PMID:21873635
(PMID:16870614), (PMID:17506858), (PMID:7681602), (PMID:8987735)
PMID:15627510
PMID:14642278
RGD PMID:7681602, PMID:8987735, PMID:9547354, PMID:16870614, PMID:17452640, PMID:17506858, PMID:20858707, PMID:12944413, PMID:10716733, PMID:21873635, PMID:15627510, PMID:14642278 MGI:MGI:2178281, MGI:MGI:3710710, MGI:MGI:6436398, RGD:1580638, RGD:8554226, RGD:13792537, RGD:8553308, RGD:8553687 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    localization 6486
      establishment of localization 4918
        transport 4774
          organic substance transport 2612
            monoamine transport 106
              serotonin transport 27
                serotonin secretion + 17
                serotonin uptake + 11
Path 2
Term Annotations click to browse term
  biological_process 20017
    localization 6486
      establishment of localization 4918
        transport 4774
          ion transport 1782
            cation transport 1281
              organic cation transport 67
                serotonin transport 27
                  serotonin secretion + 17
                  serotonin uptake + 11
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.