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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cell adhesion involved in substrate-bound cell migration
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Accession:GO:0006933 term browser browse the term
Definition:The disassembly of adhesions at the front and rear of a migrating cell. At the leading edge, adhesion disassembly accompanies the formation of new protrusions; at the cell rear, it promotes tail retraction.
Synonyms:exact_synonym: substrate-bound cell migration, cell release from substrate


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negative regulation of cell adhesion involved in substrate-bound cell migration term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5f1b ATP synthase F1 subunit beta ISO
IEA
(MGI:MGI:3719337|PMID:17612527)
GO_REF:0000107
RGD
Ensembl
PMID:17612527 GO_REF:0000107, MGI:MGI:3719337 NCBI chr 7:2,504,708...2,511,748
Ensembl chr 7:2,504,695...2,511,749
JBrowse link
G Itgb1bp1 integrin subunit beta 1 binding protein 1 ISO (MGI:MGI:5486544|PMID:18227284) RGD PMID:18227284 MGI:MGI:5486544 NCBI chr 6:43,348,927...43,363,633
Ensembl chr 6:43,348,958...43,363,335
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C ISO (PMID:21911094) RGD PMID:21911094 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692
JBrowse link
G Snai2 snail family transcriptional repressor 2 ISO MGI:MGI:2447175 (MGI:MGI:3808643|PMID:18663143) RGD PMID:18663143 MGI:MGI:3808643 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    negative regulation of biological process 5696
      negative regulation of cellular process 5144
        negative regulation of cell adhesion 297
          negative regulation of cell adhesion involved in substrate-bound cell migration 4
            substrate-bound cell migration, adhesion receptor recycling 0
Path 2
Term Annotations click to browse term
  biological_process 20014
    localization 6486
      localization of cell 1745
        cell motility 1745
          cell migration 1571
            substrate-dependent cell migration 31
              negative regulation of cell adhesion involved in substrate-bound cell migration 4
                substrate-bound cell migration, adhesion receptor recycling 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.