ONTOLOGY REPORT - ANNOTATIONS


Term:syncytium formation
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Accession:GO:0006949 term browser browse the term
Definition:The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division.


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syncytium formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 110,130,353 110,146,660 RGD:9068941
G LOC102154491 protein NYNRIN-like JBrowse link X 50,664,130 50,669,080 RGD:9068941
macrophage fusion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD81 CD81 molecule JBrowse link 18 46,466,484 46,474,236 RGD:9068941
myoblast fusion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADAM12 ADAM metallopeptidase domain 12 JBrowse link 28 35,154,899 35,484,852 RGD:9068941
G ADGRB3 adhesion G protein-coupled receptor B3 JBrowse link 12 31,336,791 32,056,238 RGD:9068941
G CACNA1H calcium voltage-gated channel subunit alpha1 H JBrowse link 6 39,510,129 39,533,129 RGD:9068941
G CAPN2 calpain 2 JBrowse link 7 40,333,379 40,367,158 RGD:13508589
RGD:9068941
G CAV3 caveolin 3 JBrowse link 20 9,384,901 9,398,055 RGD:13508589
RGD:9068941
G CDON cell adhesion associated, oncogene regulated JBrowse link 5 8,439,606 8,536,088 RGD:13508589
RGD:9068941
G DYRK1B dual specificity tyrosine phosphorylation regulated kinase 1B JBrowse link 1 113,644,191 113,652,441 RGD:9068941
G FER1L5 fer-1 like family member 5 JBrowse link 10 45,246,957 45,304,875 RGD:9068941
RGD:13508589
G KCNH1 potassium voltage-gated channel subfamily H member 1 JBrowse link 7 9,317,804 9,631,144 RGD:9068941
G MYH9 myosin heavy chain 9 JBrowse link 10 28,063,626 28,122,953 RGD:9068941
G MYMK myomaker, myoblast fusion factor JBrowse link 9 49,905,580 49,919,849 RGD:9068941
G MYMX myomixer, myoblast fusion factor JBrowse link 12 12,626,482 12,630,058 RGD:9068941
G MYOD1 myogenic differentiation 1 JBrowse link 21 40,257,792 40,260,461 RGD:13508589
RGD:9068941
G MYOF myoferlin JBrowse link 28 7,602,778 7,745,185 RGD:13508589
RGD:9068941
G NOS1 nitric oxide synthase 1 JBrowse link 26 13,787,341 13,895,176 RGD:9068941
G NPHS1 NPHS1 adhesion molecule, nephrin JBrowse link 1 116,794,891 116,814,418 RGD:9068941
G PLEKHO1 pleckstrin homology domain containing O1 JBrowse link 17 59,402,758 59,411,906 RGD:9068941
G TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 JBrowse link 36 4,850,214 5,019,453 RGD:9068941
G WNT1 Wnt family member 1 JBrowse link 27 5,588,151 5,592,254 RGD:13508589
RGD:9068941
myoblast fusion involved in skeletal muscle regeneration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD81 CD81 molecule JBrowse link 18 46,466,484 46,474,236 RGD:9068941
G CD9 CD9 molecule JBrowse link 27 38,742,539 38,754,984 RGD:9068941
G MYMK myomaker, myoblast fusion factor JBrowse link 9 49,905,580 49,919,849 RGD:13508589
RGD:9068941
G MYMX myomixer, myoblast fusion factor JBrowse link 12 12,626,482 12,630,058 RGD:9068941
G PTGFRN prostaglandin F2 receptor inhibitor JBrowse link 17 54,337,778 54,378,363 RGD:9068941
negative regulation of myoblast fusion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CFLAR CASP8 and FADD like apoptosis regulator JBrowse link 37 10,268,407 10,307,803 RGD:9068941
G CXCL10 C-X-C motif chemokine ligand 10 JBrowse link 32 598,406 599,925 RGD:13508589
RGD:9068941
negative regulation of syncytium formation by plasma membrane fusion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RAPGEF3 Rap guanine nucleotide exchange factor 3 JBrowse link 27 6,993,452 7,030,372 RGD:9068941
osteoclast fusion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD109 CD109 molecule JBrowse link 12 35,712,589 35,839,153 RGD:9068941
G CD81 CD81 molecule JBrowse link 18 46,466,484 46,474,236 RGD:9068941
G DCSTAMP dendrocyte expressed seven transmembrane protein JBrowse link 13 5,542,474 5,559,433 RGD:9068941
G SBNO2 strawberry notch homolog 2 JBrowse link 20 57,592,901 57,640,047 RGD:13508589
RGD:9068941
G SH3PXD2A SH3 and PX domains 2A JBrowse link 28 15,936,927 16,165,537 RGD:13508589
RGD:9068941
G TCTA T cell leukemia translocation altered JBrowse link 20 39,820,845 39,824,526 RGD:9068941
positive regulation of macrophage fusion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADAM9 ADAM metallopeptidase domain 9 JBrowse link 16 26,413,345 26,551,293 RGD:9068941
G DCSTAMP dendrocyte expressed seven transmembrane protein JBrowse link 13 5,542,474 5,559,433 RGD:9068941
G OCSTAMP osteoclast stimulatory transmembrane protein JBrowse link 24 33,796,582 33,802,385 RGD:9068941
G TREM2 triggering receptor expressed on myeloid cells 2 JBrowse link 12 9,915,692 9,928,322 RGD:9068941
G TYROBP TYRO protein tyrosine kinase binding protein JBrowse link 1 116,757,271 116,760,453 RGD:9068941
positive regulation of myoblast fusion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADGRB1 adhesion G protein-coupled receptor B1 JBrowse link 13 36,627,791 36,649,013 RGD:9068941
G CAPN2 calpain 2 JBrowse link 7 40,333,379 40,367,158 RGD:9068941
G CD53 CD53 molecule JBrowse link 6 41,070,132 41,089,329 RGD:13508589
RGD:9068941
G EHD1 EH domain containing 1 JBrowse link 18 52,291,304 52,312,787 RGD:9068941
G EHD2 EH domain containing 2 JBrowse link 1 108,317,471 108,336,032 RGD:9068941
G FLOT1 flotillin 1 JBrowse link 12 517,941 528,677 RGD:13508589
RGD:9068941
G FLT3LG fms related tyrosine kinase 3 ligand JBrowse link 1 107,015,222 107,025,181 RGD:9068941
G GDF15 growth differentiation factor 15 JBrowse link 20 44,633,131 44,636,842 RGD:13508589
RGD:9068941
G IL4R interleukin 4 receptor JBrowse link 6 19,254,183 19,280,973 RGD:9068941
G MAPK14 mitogen-activated protein kinase 14 JBrowse link 12 5,145,647 5,221,558 RGD:13508589
RGD:9068941
G MYF5 myogenic factor 5 JBrowse link 15 23,049,235 23,051,604 RGD:9068941
RGD:13508589
G MYF6 myogenic factor 6 JBrowse link 15 23,039,090 23,041,092 RGD:9068941
G MYOD1 myogenic differentiation 1 JBrowse link 21 40,257,792 40,260,461 RGD:9068941
RGD:13508589
G MYOG myogenin JBrowse link 7 112,116 114,604 RGD:9068941
RGD:13508589
G NFATC2 nuclear factor of activated T cells 2 JBrowse link 24 37,606,977 37,734,813 RGD:9068941
G RIPOR2 RHO family interacting cell polarization regulator 2 JBrowse link 35 22,823,053 23,041,765 RGD:9068941
RGD:13508589
G TNFSF14 TNF superfamily member 14 JBrowse link 20 53,604,101 53,607,522 RGD:9068941
positive regulation of syncytium formation by plasma membrane fusion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CAMK1 calcium/calmodulin dependent protein kinase I JBrowse link 20 8,475,902 8,486,214 RGD:9068941
G GCM1 glial cells missing transcription factor 1 JBrowse link 12 20,623,593 20,642,861 RGD:13508589
RGD:9068941
G RAPGEF3 Rap guanine nucleotide exchange factor 3 JBrowse link 27 6,993,452 7,030,372 RGD:9068941
regulation of myoblast fusion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MYOG myogenin JBrowse link 7 112,116 114,604 RGD:9068941
syncytium formation by plasma membrane fusion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC102154491 protein NYNRIN-like JBrowse link X 50,664,130 50,669,080 RGD:9068941
G VASH2 vasohibin 2 JBrowse link 7 11,073,156 11,111,813 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15806
    cellular process 14481
      syncytium formation 54
        syncytium formation by mitosis without cytokinesis 0
        syncytium formation by plasma membrane fusion + 53
Path 2
Term Annotations click to browse term
  biological_process 15806
    developmental process 5929
      anatomical structure development 5565
        anatomical structure morphogenesis 2612
          anatomical structure formation involved in morphogenesis 1070
            syncytium formation 54
              syncytium formation by mitosis without cytokinesis 0
              syncytium formation by plasma membrane fusion + 53
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.