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ONTOLOGY REPORT - ANNOTATIONS


Term:lysosome organization
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Accession:GO:0007040 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.
Synonyms:exact_synonym: lysosome organisation
 related_synonym: lysosome organization and biogenesis


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lysosome organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 ISO (PMID:15163665) BHF-UCL PMID:15163665 NCBI chr 9:75,948,831...76,096,136
Ensembl chr 9:104,076,516...104,224,188
JBrowse link
G ACP2 acid phosphatase 2, lysosomal ISO (MGI:MGI:894905|PMID:9228031)
(MGI:MGI:3522374|PMID:15604265)
MGI PMID:9228031, PMID:15604265 MGI:MGI:3522374, MGI:MGI:894905 NCBI chr11:47,185,611...47,195,174
Ensembl chr11:47,738,845...47,748,450
JBrowse link
G AKTIP AKT interacting protein ISO (PMID:18799622) UniProtKB PMID:18799622 NCBI chr16:33,731,652...33,743,571 JBrowse link
G AP3B1 adaptor related protein complex 3 subunit beta 1 ISO (MGI:MGI:1330543|PMID:9931340), (MGI:MGI:6415001|PMID:30786955) MGI PMID:9931340, PMID:30786955 MGI:MGI:1330543, MGI:MGI:6415001 NCBI chr 5:37,015,518...37,305,769
Ensembl chr 5:37,503,162...37,840,205
JBrowse link
G BECN1 beclin 1 ISO (MGI:MGI:3801567|PMID:18497889) MGI PMID:18497889 MGI:MGI:3801567 NCBI chr17:14,493,619...14,507,809
Ensembl chr17:14,719,781...14,733,286
JBrowse link
G CHMP5 charged multivesicular body protein 5 ISO (MGI:MGI:3622513|PMID:16567502) MGI PMID:16567502 MGI:MGI:3622513 NCBI chr 9:33,043,148...33,059,564
Ensembl chr 9:33,851,377...33,867,942
JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO (MGI:MGI:1343910|PMID:10440905)
(MGI:MGI:3527911|PMID:15588329)
(MGI:MGI:1337525|PMID:10191119), (MGI:MGI:1346962|PMID:10527801)
MGI PMID:10191119, PMID:10440905, PMID:10527801, PMID:15588329 MGI:MGI:1337525, MGI:MGI:1343910, MGI:MGI:1346962, MGI:MGI:3527911
G CLN5 CLN5 intracellular trafficking protein ISO (MGI:MGI:3512689|PMID:15459177) MGI PMID:15459177 MGI:MGI:3512689 NCBI chr13:58,207,542...58,220,697
Ensembl chr13:77,253,203...77,263,759
JBrowse link
G CLN6 CLN6 transmembrane ER protein ISO (MGI:MGI:1203267|PMID:9600738), (MGI:MGI:5751614|PMID:26681805) MGI PMID:9600738, PMID:26681805 MGI:MGI:1203267, MGI:MGI:5751614 NCBI chr15:47,156,583...47,215,805
Ensembl chr15:65,425,472...65,985,242
JBrowse link
G CLN8 CLN8 transmembrane ER and ERGIC protein ISO (MGI:MGI:1333651|PMID:10087069), (MGI:MGI:65559|PMID:8144516), (MGI:MGI:66707|PMID:8160780), (MGI:MGI:71226|PMID:7613514) MGI PMID:7613514, PMID:8144516, PMID:8160780, PMID:10087069 MGI:MGI:1333651, MGI:MGI:65559, MGI:MGI:66707, MGI:MGI:71226 NCBI chr 8:5,587,875...5,606,883
Ensembl chr 8:1,658,694...1,700,754
JBrowse link
G CLVS1 clavesin 1 ISO PMID:19651769 UniProt PMID:19651769 RGD:8553526 NCBI chr 8:57,703,459...57,921,997
Ensembl chr 8:59,252,291...59,630,784
JBrowse link
G CLVS2 clavesin 2 ISO PMID:19651769 UniProt PMID:19651769 RGD:8553526 NCBI chr 6:120,784,849...120,858,655
Ensembl chr 6:124,907,667...124,975,839
JBrowse link
G FAM160A2 family with sequence similarity 160 member A2 ISO (PMID:18799622) UniProtKB PMID:18799622 NCBI chr11:6,345,227...6,368,675
Ensembl chr11:6,027,300...6,050,850
JBrowse link
G GAA glucosidase alpha, acid ISO (PMID:7717400)
(MGI:MGI:1195358|PMID:9384603), (MGI:MGI:1346721|PMID:10547605), (MGI:MGI:2136118|PMID:11328962), (MGI:MGI:3664400|PMID:12115977)
(MGI:MGI:1275872|PMID:9668092), (MGI:MGI:3618942|PMID:15169761)
BHF-UCL
MGI
PMID:7717400, PMID:9384603, PMID:9668092, PMID:10547605, PMID:11328962, PMID:12115977, PMID:15169761 MGI:MGI:1195358, MGI:MGI:1275872, MGI:MGI:1346721, MGI:MGI:2136118, MGI:MGI:3618942, MGI:MGI:3664400 NCBI chr17:74,188,296...74,206,593
Ensembl chr17:79,723,699...79,741,839
JBrowse link
G GNPTAB N-acetylglucosamine-1-phosphate transferase subunits alpha and beta ISO (PMID:21719679) UniProtKB PMID:21719679 NCBI chr12:99,328,026...99,418,151
Ensembl chr12:102,729,615...102,816,560
JBrowse link
G GRN granulin precursor ISO (MGI:MGI:6274951|PMID:27789271) UniProt PMID:27789271 MGI:MGI:6274951 NCBI chr17:13,046,329...13,054,236
Ensembl chr17:13,211,784...13,219,609
JBrowse link
G HEXB hexosaminidase subunit beta ISO (MGI:MGI:1271008|PMID:9645704), (MGI:MGI:78473|PMID:8789434)
(MGI:MGI:83770|PMID:8896570), (MGI:MGI:894634|PMID:9184660)
MGI PMID:8789434, PMID:8896570, PMID:9184660, PMID:9645704 MGI:MGI:1271008, MGI:MGI:78473, MGI:MGI:83770, MGI:MGI:894634 NCBI chr 5:40,589,448...40,625,176
Ensembl chr 5:41,199,681...41,232,693
JBrowse link
G HOOK1 hook microtubule tethering protein 1 ISO (PMID:18799622) UniProtKB PMID:18799622 NCBI chr 1:59,072,565...59,134,191
Ensembl chr 1:60,777,769...60,839,384
JBrowse link
G HOOK2 hook microtubule tethering protein 2 ISO (PMID:18799622) UniProtKB PMID:18799622 NCBI chr19:12,325,578...12,340,754
Ensembl chr19:13,070,289...13,082,612
JBrowse link
G HOOK3 hook microtubule tethering protein 3 ISO (PMID:18799622) UniProtKB PMID:18799622 NCBI chr 8:42,145,427...42,278,727
Ensembl chr 8:39,595,762...39,711,043
JBrowse link
G HPS1 HPS1 biogenesis of lysosomal organelles complex 3 subunit 1 ISO (MGI:MGI:6415001|PMID:30786955) MGI PMID:30786955 MGI:MGI:6415001 NCBI chr10:95,030,626...95,061,415
Ensembl chr10:98,526,113...98,552,922
JBrowse link
G HPS4 HPS4 biogenesis of lysosomal organelles complex 3 subunit 2 ISO (PMID:12663659) UniProtKB PMID:12663659 NCBI chr22:7,513,397...7,545,782
Ensembl chr22:25,236,360...25,268,699
JBrowse link
G IDUA alpha-L-iduronidase ISO (MGI:MGI:4414887|PMID:19751987)
(MGI:MGI:86916|PMID:9097952)
MGI PMID:9097952, PMID:19751987 MGI:MGI:4414887, MGI:MGI:86916 NCBI chr 4:1,102,288...1,120,973
Ensembl chr 4:1,020,582...1,037,877
JBrowse link
G LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 ISO (MGI:MGI:4887551|PMID:19177150) UniProtKB PMID:19177150 MGI:MGI:4887551 NCBI chr11:67,177,580...67,183,631
Ensembl chr11:70,390,141...70,407,246
JBrowse link
G LOC100986229 CUGBP Elav-like family member 6 ISO (MGI:MGI:83770|PMID:8896570), (MGI:MGI:894634|PMID:9184660)
(MGI:MGI:77946|PMID:8747922)
(MGI:MGI:1097747|PMID:9302266), (MGI:MGI:1271008|PMID:9645704), (MGI:MGI:1352198|PMID:10591619), (MGI:MGI:3033296|PMID:14972652)
(MGI:MGI:69059|PMID:7937929), (MGI:MGI:86923|PMID:9103204)
MGI PMID:7937929, PMID:8747922, PMID:8896570, PMID:9103204, PMID:9184660, PMID:9302266, PMID:9645704, PMID:10591619, PMID:14972652 MGI:MGI:1097747, MGI:MGI:1271008, MGI:MGI:1352198, MGI:MGI:3033296, MGI:MGI:69059, MGI:MGI:77946, MGI:MGI:83770, MGI:MGI:86923, MGI:MGI:894634 NCBI chr15:51,235,123...51,326,832 JBrowse link
G LRRK2 leucine rich repeat kinase 2 ISO (PMID:25416817) ParkinsonsUK-UCL PMID:25416817 NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462
JBrowse link
G LYST lysosomal trafficking regulator ISO (MGI:MGI:1099544|PMID:9368050)
(MGI:MGI:53816|PMID:4697831), (MGI:MGI:53992|PMID:1113502), (MGI:MGI:55104|PMID:6170520), (MGI:MGI:56449|PMID:4031470)
MGI PMID:1113502, PMID:4031470, PMID:4697831, PMID:6170520, PMID:9368050 MGI:MGI:1099544, MGI:MGI:53816, MGI:MGI:53992, MGI:MGI:55104, MGI:MGI:56449 NCBI chr 1:211,229,800...211,451,947
Ensembl chr 1:216,231,824...216,436,293
JBrowse link
G MBTPS1 membrane bound transcription factor peptidase, site 1 ISO (PMID:21719679) UniProtKB PMID:21719679 NCBI chr16:64,719,971...64,783,119
Ensembl chr16:84,063,508...84,126,000
JBrowse link
G MFSD8 major facilitator superfamily domain containing 8 ISO (MGI:MGI:5575728|PMID:24423645)
(MGI:MGI:5751614|PMID:26681805)
MGI PMID:24423645, PMID:26681805 MGI:MGI:5575728, MGI:MGI:5751614 NCBI chr 4:120,087,477...120,137,550
Ensembl chr 4:131,391,361...131,439,590
JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO (PMID:22692423) UniProt PMID:22692423 NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841
JBrowse link
G MYO7A myosin VIIA ISO (PMID:16001398) UniProtKB PMID:16001398 NCBI chr11:72,187,024...72,265,931
Ensembl chr11:75,834,185...75,907,752
JBrowse link
G NAGLU N-acetyl-alpha-glucosaminidase ISO (MGI:MGI:3769195|PMID:17712420) MGI PMID:17712420 MGI:MGI:3769195 NCBI chr17:14,772,054...14,780,398
Ensembl chr17:14,996,420...15,004,242
JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 ISO (MGI:MGI:3612221|PMID:16368712)
(MGI:MGI:3654230|PMID:16542649)
MGI PMID:16368712, PMID:16542649 MGI:MGI:3612221, MGI:MGI:3654230 NCBI chr 1:39,358,424...39,383,087
Ensembl chr 1:40,683,841...40,708,609
JBrowse link
G SNAPIN SNAP associated protein ISO (MGI:MGI:4879078|PMID:20920792) MGI PMID:20920792 MGI:MGI:4879078 NCBI chr 1:129,014,668...129,018,428
Ensembl chr 1:132,644,320...132,647,095
JBrowse link
G SPG11 SPG11 vesicle trafficking associated, spatacsin ISO (MGI:MGI:5749311|PMID:26284655) MGI PMID:26284655 MGI:MGI:5749311 NCBI chr15:23,519,311...23,620,532
Ensembl chr15:41,688,081...41,788,616
JBrowse link
G TFEB transcription factor EB ISO (PMID:23434374)
(PMID:22692423)
UniProtKB
UniProt
PMID:22692423, PMID:23434374 NCBI chr 6:41,268,169...41,320,822
Ensembl chr 6:42,574,416...42,627,031
JBrowse link
G TMEM106B transmembrane protein 106B ISO (MGI:MGI:5588048|PMID:25066864) MGI PMID:25066864 MGI:MGI:5588048 NCBI chr 7:12,905,192...12,931,170
Ensembl chr 7:12,250,010...12,270,693
JBrowse link
G TPCN2 two pore segment channel 2 ISO (PMID:25416817) ParkinsonsUK-UCL PMID:25416817 NCBI chr11:64,139,512...64,227,913 JBrowse link
G TPP1 tripeptidyl peptidase 1 ISO (MGI:MGI:3522013|PMID:15483130) MGI PMID:15483130 MGI:MGI:3522013 NCBI chr11:6,744,815...6,751,556
Ensembl chr11:6,427,522...6,434,222
JBrowse link
G VPS18 VPS18 core subunit of CORVET and HOPS complexes ISO (PMID:18799622) UniProtKB PMID:18799622 NCBI chr15:19,836,707...19,846,231
Ensembl chr15:38,086,518...38,095,835
JBrowse link
G VPS35 VPS35 retromer complex component ISO (MGI:MGI:5694519|PMID:26203154) ParkinsonsUK-UCL PMID:26203154 MGI:MGI:5694519 NCBI chr16:26,924,901...26,954,443
Ensembl chr16:45,817,371...45,846,531
JBrowse link
G WASHC5 WASH complex subunit 5 ISO (MGI:MGI:6199426|PMID:30061306) MGI PMID:30061306 MGI:MGI:6199426 NCBI chr 8:121,710,118...121,777,977
Ensembl chr 8:124,461,424...124,529,262
JBrowse link
G ZKSCAN3 zinc finger with KRAB and SCAN domains 3 ISO (PMID:23434374) UniProtKB PMID:23434374 NCBI chr 6:28,157,736...28,174,906
Ensembl chr 6:28,828,298...28,847,596
JBrowse link
lysosomal lumen acidification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6AP2 ATPase H+ transporting accessory protein 2 ISO (PMID:32276428) UniProt PMID:32276428 NCBI chr  X:33,026,525...33,052,252
Ensembl chr  X:40,730,677...40,756,209
JBrowse link
G CCDC115 coiled-coil domain containing 115 ISO (PMID:28296633) UniProtKB PMID:28296633 NCBI chr2B:28,624,800...28,629,543 JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO (PMID:11722572) UniProtKB PMID:11722572
G CLN5 CLN5 intracellular trafficking protein ISO (PMID:11722572) UniProtKB PMID:11722572 NCBI chr13:58,207,542...58,220,697
Ensembl chr13:77,253,203...77,263,759
JBrowse link
G CLN6 CLN6 transmembrane ER protein ISO (PMID:11722572) UniProtKB PMID:11722572 NCBI chr15:47,156,583...47,215,805
Ensembl chr15:65,425,472...65,985,242
JBrowse link
G GRN granulin precursor ISO (PMID:28073925) UniProt PMID:28073925 NCBI chr17:13,046,329...13,054,236
Ensembl chr17:13,211,784...13,219,609
JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 ISO (PMID:11722572) UniProtKB PMID:11722572 NCBI chr 1:39,358,424...39,383,087
Ensembl chr 1:40,683,841...40,708,609
JBrowse link
G SNAPIN SNAP associated protein ISO (MGI:MGI:4879078|PMID:20920792) MGI PMID:20920792 MGI:MGI:4879078 NCBI chr 1:129,014,668...129,018,428
Ensembl chr 1:132,644,320...132,647,095
JBrowse link
G TMEM199 transmembrane protein 199 ISO (PMID:28296633) UniProtKB PMID:28296633 NCBI chr17:28,412,229...28,416,840
Ensembl chr17:28,914,604...28,919,194
JBrowse link
G TMEM9 transmembrane protein 9 ISO (PMID:30374053) UniProt PMID:30374053 NCBI chr 1:176,734,640...176,771,476
Ensembl chr 1:181,037,050...181,056,841
JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO (PMID:10924275) UniProtKB PMID:10924275
lysosomal membrane organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARF1 ADP ribosylation factor 1 ISO RGD PMID:9538255 RGD:9684948 NCBI chr 1:203,484,803...203,501,395
Ensembl chr 1:208,695,615...208,712,105
JBrowse link
negative regulation of lysosome organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BECN1 beclin 1 ISO RGD PMID:25561470 RGD:11561937 NCBI chr17:14,493,619...14,507,809
Ensembl chr17:14,719,781...14,733,286
JBrowse link
phagolysosome assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CORO1A coronin 1A ISO (PMID:12132654) UniProtKB PMID:12132654 Ensembl chr16:30,550,383...30,556,196 JBrowse link
G MYO7A myosin VIIA ISO (MGI:MGI:2662763|PMID:12743369) MGI PMID:12743369 MGI:MGI:2662763 NCBI chr11:72,187,024...72,265,931
Ensembl chr11:75,834,185...75,907,752
JBrowse link
G P2RX7 purinergic receptor P2X 7 ISO (MGI:MGI:3699774|PMID:11544318) MGI PMID:11544318 MGI:MGI:3699774 NCBI chr12:118,731,761...118,786,039
Ensembl chr12:122,102,888...122,154,068
JBrowse link
G SRPX sushi repeat containing protein X-linked ISO (MGI:MGI:3852261|PMID:19368996) MGI PMID:19368996 MGI:MGI:3852261 NCBI chr  X:30,598,574...30,670,464
Ensembl chr  X:38,303,313...38,378,770
JBrowse link
phagosome-lysosome docking term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO (MGI:MGI:5698740|PMID:26450516) UniProt PMID:26450516 MGI:MGI:5698740
phagosome-lysosome fusion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO (MGI:MGI:5698740|PMID:26450516) UniProt PMID:26450516 MGI:MGI:5698740
G PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing ISO (PMID:28779020)
(MGI:MGI:6103777|PMID:28779020)
UniProt PMID:28779020 MGI:MGI:6103777 NCBI chr2B:95,505,376...95,597,792
Ensembl chr2B:213,628,997...213,721,299
JBrowse link
G PLA2G5 phospholipase A2 group V ISO (MGI:MGI:3841317|PMID:19342668) UniProt PMID:19342668 MGI:MGI:3841317 NCBI chr 1:18,983,104...19,046,834
Ensembl chr 1:20,068,110...20,089,840
JBrowse link
G RAB20 RAB20, member RAS oncogene family ISO (PMID:21255211) UniProtKB PMID:21255211 NCBI chr13:91,660,142...91,698,215
Ensembl chr13:110,778,119...110,815,408
JBrowse link
G RAB34 RAB34, member RAS oncogene family ISO (MGI:MGI:5467668|PMID:23197834)
(PMID:21255211)
ParkinsonsUK-UCL
UniProtKB
PMID:21255211, PMID:23197834 MGI:MGI:5467668 NCBI chr17:28,057,077...28,061,234
Ensembl chr17:28,562,118...28,566,242
JBrowse link
G RAB39A RAB39A, member RAS oncogene family ISO (PMID:21255211) UniProtKB PMID:21255211 NCBI chr11:102,814,825...102,851,700
Ensembl chr11:106,291,348...106,326,587
JBrowse link
G RAB7A RAB7A, member RAS oncogene family ISO (PMID:21255211) UniProtKB PMID:21255211 NCBI chr 3:125,784,604...125,873,051 JBrowse link
G SYT7 synaptotagmin 7 ISO (MGI:MGI:3690533|PMID:16982801) UniProtKB PMID:16982801 MGI:MGI:3690533 NCBI chr11:56,814,694...56,880,439 JBrowse link
G TMEM175 transmembrane protein 175 ISO (MGI:MGI:5693670|PMID:26317472) UniProtKB PMID:26317472 MGI:MGI:5693670 NCBI chr 4:1,049,647...1,074,903
Ensembl chr 4:967,494...993,030
JBrowse link
phagosome-lysosome fusion involved in apoptotic cell clearance term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPG11 SPG11 vesicle trafficking associated, spatacsin ISO (MGI:MGI:5749311|PMID:26284655) MGI PMID:26284655 MGI:MGI:5749311 NCBI chr15:23,519,311...23,620,532
Ensembl chr15:41,688,081...41,788,616
JBrowse link
positive regulation of lysosomal membrane permeability term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:9038169 RGD:10059368 NCBI chr11:117,890,545...117,895,262
Ensembl chr11:121,809,800...121,815,773
JBrowse link
G MT3 metallothionein 3 ISO (MGI:MGI:4881636|PMID:20544854) UniProtKB PMID:20544854 MGI:MGI:4881636 NCBI chr16:36,875,919...36,877,558 JBrowse link
positive regulation of lysosome organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRN granulin precursor ISO (PMID:28073925)
(MGI:MGI:5905514|PMID:28073925)
UniProt PMID:28073925 MGI:MGI:5905514 NCBI chr17:13,046,329...13,054,236
Ensembl chr17:13,211,784...13,219,609
JBrowse link
regulation of lysosomal lumen pH term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRK2 leucine rich repeat kinase 2 ISO (PMID:22012985) ParkinsonsUK-UCL PMID:22012985 NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462
JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 ISO (PMID:31001245) UniProt PMID:31001245 NCBI chr  X:23,159,321...23,178,192
Ensembl chr  X:30,716,617...30,717,522
JBrowse link
G TMEM165 transmembrane protein 165 ISO (PMID:23569283) UniProtKB PMID:23569283 NCBI chr 4:68,484,896...68,541,808
Ensembl chr 4:75,075,427...75,104,629
JBrowse link
G TMEM175 transmembrane protein 175 ISO (MGI:MGI:5693670|PMID:26317472) UniProtKB PMID:26317472 MGI:MGI:5693670 NCBI chr 4:1,049,647...1,074,903
Ensembl chr 4:967,494...993,030
JBrowse link
G VPS33A VPS33A core subunit of CORVET and HOPS complexes ISO (PMID:28013294) UniProtKB PMID:28013294 NCBI chr12:119,831,693...119,868,132 JBrowse link
regulation of lysosomal membrane permeability term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LAPTM4B lysosomal protein transmembrane 4 beta ISO (PMID:26280656) UniProtKB PMID:26280656 NCBI chr 8:94,414,275...94,491,483 JBrowse link
regulation of lysosome organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LAPTM4B lysosomal protein transmembrane 4 beta ISO (PMID:26280656) UniProtKB PMID:26280656 NCBI chr 8:94,414,275...94,491,483 JBrowse link
G TREX1 three prime repair exonuclease 1 ISO (MGI:MGI:5460923|PMID:23160154) MGI PMID:23160154 MGI:MGI:5460923 NCBI chr 3:48,387,762...48,389,693
Ensembl chr 3:49,470,222...49,471,331
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12527
    cellular process 11621
      cellular component organization or biogenesis 4979
        cellular component organization 4899
          organelle organization 3023
            vacuole organization 147
              lytic vacuole organization 66
                lysosome organization 66
                  lysosomal membrane organization + 4
                  negative regulation of lysosome organization 1
                  phagolysosome assembly + 14
                  positive regulation of lysosome organization 1
                  regulation of lysosomal lumen pH + 15
                  regulation of lysosome organization + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.