Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:lysosome organization
go back to main search page
Accession:GO:0007040 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.
Synonyms:exact_synonym: lysosome organisation
 related_synonym: lysosome organization and biogenesis


show annotations for term's descendants           Sort by:
 
lysosome organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 IDA (PMID:15163665) BHF-UCL PMID:15163665 NCBI chr 9:104,781,006...104,928,232
Ensembl chr 9:104,781,006...104,928,155
JBrowse link
G AC001226.2 novel protein IBA (PMID:21873635) GO_Central PMID:21873635 Ensembl chr13:76,992,078...77,129,589 JBrowse link
G ACP2 acid phosphatase 2, lysosomal IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:47,239,302...47,248,814
Ensembl chr11:47,239,302...47,248,906
JBrowse link
G ACP3 acid phosphatase 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:132,317,403...132,368,765
Ensembl chr 3:132,317,369...132,368,298
JBrowse link
G ACP4 acid phosphatase 4 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr19:50,790,415...50,795,219
Ensembl chr19:50,790,415...50,795,219
JBrowse link
G AKTIP AKT interacting protein IMP (PMID:18799622) UniProtKB PMID:18799622 NCBI chr16:53,491,040...53,504,411
Ensembl chr16:53,491,040...53,504,411
JBrowse link
G AP3B1 adaptor related protein complex 3 subunit beta 1 IEA Ensembl GO_REF:0000107 NCBI chr 5:78,000,522...78,294,704
Ensembl chr 5:78,000,525...78,294,755
Ensembl chr 5:78,000,525...78,294,755
JBrowse link
G ARSB arylsulfatase B TAS (PMID:1718978) PINC PMID:1718978 NCBI chr 5:78,777,209...78,986,087
Ensembl chr 5:78,777,209...78,986,087
JBrowse link
G BECN1 beclin 1 ISO (MGI:MGI:3801567|PMID:18497889) MGI PMID:18497889 MGI:MGI:3801567 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
JBrowse link
G CHMP5 charged multivesicular body protein 5 IEA Ensembl GO_REF:0000107 NCBI chr 9:33,265,049...33,282,070
Ensembl chr 9:33,264,879...33,282,070
JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISS
IBA
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000024 NCBI chr16:28,466,653...28,492,082
Ensembl chr16:28,456,371...28,492,098
Ensembl chr16:28,456,371...28,492,098
JBrowse link
G CLN5 CLN5 intracellular trafficking protein IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:76,992,081...77,005,117
Ensembl chr13:76,990,660...77,019,143
JBrowse link
G CLN6 CLN6 transmembrane ER protein IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:68,206,992...68,229,728
Ensembl chr15:68,206,992...68,257,211
JBrowse link
G CLN8 CLN8 transmembrane ER and ERGIC protein IEA Ensembl GO_REF:0000107 NCBI chr 8:1,755,778...1,786,570
Ensembl chr 8:1,755,778...1,801,711
JBrowse link
G CLVS1 clavesin 1 IEA
IBA
ISS
(PMID:21873635) InterPro
GO_Central
UniProtKB
PMID:21873635 GO_REF:0000002, GO_REF:0000024 NCBI chr 8:60,964,833...61,501,629
Ensembl chr 8:61,057,158...61,501,645
JBrowse link
G CLVS2 clavesin 2 ISS
IBA
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000024 NCBI chr 6:122,996,235...123,072,925
Ensembl chr 6:122,996,235...123,072,925
JBrowse link
G FAM160A2 family with sequence similarity 160 member A2 IMP (PMID:18799622) UniProtKB PMID:18799622 NCBI chr11:6,211,338...6,234,663
Ensembl chr11:6,211,335...6,234,711
Ensembl chr11:6,211,335...6,234,711
JBrowse link
G GAA glucosidase alpha, acid IMP (PMID:7717400) BHF-UCL PMID:7717400 NCBI chr17:80,101,535...80,119,881
Ensembl chr17:80,101,556...80,119,881
JBrowse link
G GBA glucosylceramidase beta IMP (PMID:27378698) UniProt PMID:27378698 NCBI chr 1:155,234,452...155,244,627
Ensembl chr 1:155,234,452...155,244,699
JBrowse link
G GNPTAB N-acetylglucosamine-1-phosphate transferase subunits alpha and beta IMP (PMID:21719679) UniProtKB PMID:21719679 NCBI chr12:101,745,499...101,830,959
Ensembl chr12:101,745,499...101,830,959
JBrowse link
G GRN granulin precursor ISS UniProt GO_REF:0000024 NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106
JBrowse link
G HEXA hexosaminidase subunit alpha ISO (MGI:MGI:83770|PMID:8896570), (MGI:MGI:894634|PMID:9184660)
(MGI:MGI:77946|PMID:8747922)
(MGI:MGI:1097747|PMID:9302266), (MGI:MGI:1271008|PMID:9645704), (MGI:MGI:1352198|PMID:10591619), (MGI:MGI:3033296|PMID:14972652)
(MGI:MGI:69059|PMID:7937929), (MGI:MGI:86923|PMID:9103204)
MGI PMID:7937929, PMID:8747922, PMID:8896570, PMID:9103204, PMID:9184660, PMID:9302266, PMID:9645704, PMID:10591619, PMID:14972652 MGI:MGI:1097747, MGI:MGI:1271008, MGI:MGI:1352198, MGI:MGI:3033296, MGI:MGI:69059, MGI:MGI:77946, MGI:MGI:83770, MGI:MGI:86923, MGI:MGI:894634 NCBI chr15:72,340,924...72,376,014
Ensembl chr15:72,340,919...72,376,476
Ensembl chr15:72,340,919...72,376,476
JBrowse link
G HEXB hexosaminidase subunit beta IEA Ensembl GO_REF:0000107 NCBI chr 5:74,640,023...74,721,288
Ensembl chr 5:74,640,023...74,722,647
JBrowse link
G HOOK1 hook microtubule tethering protein 1 IMP (PMID:18799622) UniProtKB PMID:18799622 NCBI chr 1:59,814,922...59,876,370
Ensembl chr 1:59,814,786...59,876,322
Ensembl chr 1:59,814,786...59,876,322
JBrowse link
G HOOK2 hook microtubule tethering protein 2 IMP (PMID:18799622) UniProtKB PMID:18799622 NCBI chr19:12,763,003...12,775,552
Ensembl chr19:12,763,003...12,872,740
JBrowse link
G HOOK3 hook microtubule tethering protein 3 IMP (PMID:18799622) UniProtKB PMID:18799622 NCBI chr 8:42,896,978...43,030,535
Ensembl chr 8:42,896,946...43,030,535
JBrowse link
G HPS1 HPS1 biogenesis of lysosomal organelles complex 3 subunit 1 TAS (PMID:10625677) PINC PMID:10625677 NCBI chr10:98,416,193...98,446,963
Ensembl chr10:98,416,198...98,446,947
JBrowse link
G HPS4 HPS4 biogenesis of lysosomal organelles complex 3 subunit 2 IDA (PMID:12663659) UniProtKB PMID:12663659 NCBI chr22:26,443,109...26,483,863
Ensembl chr22:26,443,423...26,483,837
JBrowse link
G IDUA alpha-L-iduronidase ISO (MGI:MGI:4414887|PMID:19751987)
(MGI:MGI:86916|PMID:9097952)
MGI PMID:9097952, PMID:19751987 MGI:MGI:4414887, MGI:MGI:86916 NCBI chr 4:986,997...1,004,564
Ensembl chr 4:986,997...1,004,564
JBrowse link
G LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 IEA
ISS
InterPro
UniProtKB
GO_REF:0000002, GO_REF:0000024 NCBI chr11:72,097,292...72,103,297
Ensembl chr11:72,085,895...72,103,297
JBrowse link
G LRRK2 leucine rich repeat kinase 2 IMP (PMID:25416817) ParkinsonsUK-UCL PMID:25416817 NCBI chr12:40,224,890...40,369,285
Ensembl chr12:40,196,744...40,369,285
JBrowse link
G LYST lysosomal trafficking regulator IEA InterPro GO_REF:0000002 NCBI chr 1:235,661,031...235,883,713
Ensembl chr 1:235,661,041...235,883,640
JBrowse link
G MBTPS1 membrane bound transcription factor peptidase, site 1 IMP (PMID:21719679) UniProtKB PMID:21719679 NCBI chr16:84,053,763...84,116,942
Ensembl chr16:84,053,761...84,116,942
JBrowse link
G MFSD8 major facilitator superfamily domain containing 8 IEA Ensembl GO_REF:0000107 NCBI chr 4:127,917,732...127,965,988
Ensembl chr 4:127,917,732...127,966,034
Ensembl chr 4:127,917,732...127,966,034
JBrowse link
G MTOR mechanistic target of rapamycin kinase IDA (PMID:22692423) UniProt PMID:22692423 NCBI chr 1:11,106,535...11,273,497
Ensembl chr 1:11,106,535...11,262,551
JBrowse link
G MYO7A myosin VIIA IDA (PMID:16001398) UniProtKB PMID:16001398 NCBI chr11:77,128,192...77,215,241
Ensembl chr11:77,128,246...77,215,241
JBrowse link
G NAGLU N-acetyl-alpha-glucosaminidase IEA Ensembl GO_REF:0000107 NCBI chr17:42,534,238...42,544,449
Ensembl chr17:42,536,241...42,544,449
JBrowse link
G NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase TAS (PMID:10551838) PINC PMID:10551838 NCBI chr16:5,024,844...5,033,940
Ensembl chr16:5,024,844...5,034,141
JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 ISO (MGI:MGI:3612221|PMID:16368712)
(MGI:MGI:3654230|PMID:16542649)
MGI PMID:16368712, PMID:16542649 MGI:MGI:3612221, MGI:MGI:3654230 NCBI chr 1:40,071,461...40,097,252
Ensembl chr 1:40,072,710...40,097,260
Ensembl chr 1:40,072,710...40,097,260
JBrowse link
G SNAPIN SNAP associated protein IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:153,658,654...153,661,852
Ensembl chr 1:153,658,703...153,661,852
JBrowse link
G SPG11 SPG11 vesicle trafficking associated, spatacsin ISO (MGI:MGI:5749311|PMID:26284655) MGI PMID:26284655 MGI:MGI:5749311 NCBI chr15:44,562,696...44,663,678
Ensembl chr15:44,562,696...44,663,678
JBrowse link
G TFEB transcription factor EB IMP
IDA
(PMID:23434374)
(PMID:22692423)
UniProtKB
UniProt
PMID:22692423, PMID:23434374 NCBI chr 6:41,683,978...41,736,223
Ensembl chr 6:41,683,978...41,736,259
JBrowse link
G TMEM106B transmembrane protein 106B IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:12,211,294...12,243,367
Ensembl chr 7:12,211,270...12,243,367
JBrowse link
G TPCN2 two pore segment channel 2 IGI (PMID:25416817) ParkinsonsUK-UCL PMID:25416817 NCBI chr11:69,048,932...69,090,597
Ensembl chr11:69,048,932...69,136,316
JBrowse link
G TPP1 tripeptidyl peptidase 1 ISS UniProtKB GO_REF:0000024 NCBI chr11:6,612,768...6,619,422
Ensembl chr11:6,612,768...6,619,448
JBrowse link
G VPS18 VPS18 core subunit of CORVET and HOPS complexes IDA
IBA
(PMID:18799622)
(PMID:21873635)
UniProtKB
GO_Central
PMID:18799622, PMID:21873635 NCBI chr15:40,894,410...40,903,975
Ensembl chr15:40,894,450...40,903,975
JBrowse link
G VPS35 VPS35 retromer complex component IEA Ensembl GO_REF:0000107 NCBI chr16:46,656,132...46,689,194
Ensembl chr16:46,656,132...46,689,518
JBrowse link
G WASHC5 WASH complex subunit 5 IEA Ensembl GO_REF:0000107 NCBI chr 8:125,024,260...125,091,796
Ensembl chr 8:125,024,260...125,091,819
JBrowse link
G ZKSCAN3 zinc finger with KRAB and SCAN domains 3 IMP (PMID:23434374) UniProtKB PMID:23434374 NCBI chr 6:28,349,913...28,369,174
Ensembl chr 6:28,349,947...28,369,172
JBrowse link
lysosomal lumen acidification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6AP2 ATPase H+ transporting accessory protein 2 IMP (PMID:32276428) UniProt PMID:32276428 NCBI chr  X:40,580,970...40,606,848
Ensembl chr  X:40,579,372...40,606,848
JBrowse link
G CCDC115 coiled-coil domain containing 115 IMP (PMID:28296633) UniProtKB PMID:28296633 NCBI chr 2:130,337,933...130,342,681
Ensembl chr 2:130,337,933...130,342,699
JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin IMP
IBA
(PMID:11722572)
(PMID:21873635)
UniProtKB
GO_Central
PMID:11722572, PMID:21873635 NCBI chr16:28,466,653...28,492,082
Ensembl chr16:28,456,371...28,492,098
Ensembl chr16:28,456,371...28,492,098
JBrowse link
G CLN5 CLN5 intracellular trafficking protein IMP (PMID:11722572) UniProtKB PMID:11722572 NCBI chr13:76,992,081...77,005,117
Ensembl chr13:76,990,660...77,019,143
JBrowse link
G CLN6 CLN6 transmembrane ER protein IMP (PMID:11722572) UniProtKB PMID:11722572 NCBI chr15:68,206,992...68,229,728
Ensembl chr15:68,206,992...68,257,211
JBrowse link
G GRN granulin precursor IMP (PMID:28073925) UniProt PMID:28073925 NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106
JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 IMP (PMID:11722572) UniProtKB PMID:11722572 NCBI chr 1:40,071,461...40,097,252
Ensembl chr 1:40,072,710...40,097,260
Ensembl chr 1:40,072,710...40,097,260
JBrowse link
G SNAPIN SNAP associated protein IEA Ensembl GO_REF:0000107 NCBI chr 1:153,658,654...153,661,852
Ensembl chr 1:153,658,703...153,661,852
JBrowse link
G TMEM199 transmembrane protein 199 IMP (PMID:28296633) UniProtKB PMID:28296633 NCBI chr17:28,357,647...28,363,683
Ensembl chr17:28,357,642...28,363,683
JBrowse link
G TMEM9 transmembrane protein 9 IDA (PMID:30374053) UniProt PMID:30374053 NCBI chr 1:201,134,772...201,171,625
Ensembl chr 1:201,134,772...201,171,574
JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin IDA (PMID:10924275) UniProtKB PMID:10924275 NCBI chr16:28,466,653...28,492,082
Ensembl chr16:28,456,371...28,492,098
Ensembl chr16:28,456,371...28,492,098
JBrowse link
lysosomal membrane organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARF1 ADP ribosylation factor 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:228,082,708...228,099,212
Ensembl chr 1:228,082,660...228,099,212
JBrowse link
negative regulation of lysosome organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BECN1 beclin 1 ISO RGD PMID:25561470 RGD:11561937 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
JBrowse link
phagolysosome assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CORO1A coronin 1A IEA
IMP
(PMID:12132654) InterPro
UniProtKB
PMID:12132654 GO_REF:0000002 NCBI chr16:30,183,602...30,189,076
Ensembl chr16:30,182,827...30,189,076
JBrowse link
G MYO7A myosin VIIA IEA Ensembl GO_REF:0000107 NCBI chr11:77,128,192...77,215,241
Ensembl chr11:77,128,246...77,215,241
JBrowse link
G P2RX7 purinergic receptor P2X 7 IEA Ensembl GO_REF:0000107 NCBI chr12:121,132,819...121,188,032
Ensembl chr12:121,132,819...121,188,032
JBrowse link
G SRPX sushi repeat containing protein X-linked IEA Ensembl GO_REF:0000107 NCBI chr  X:38,149,339...38,220,881
Ensembl chr  X:38,149,336...38,220,924
JBrowse link
phagolysosome assembly involved in apoptotic cell clearance term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RAB14 RAB14, member RAS oncogene family IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:121,178,133...121,201,869
Ensembl chr 9:121,178,133...121,223,014
JBrowse link
phagosome-lysosome docking term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISS UniProt GO_REF:0000024 NCBI chr16:28,466,653...28,492,082
Ensembl chr16:28,456,371...28,492,098
Ensembl chr16:28,456,371...28,492,098
JBrowse link
phagosome-lysosome fusion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISS UniProt GO_REF:0000024 NCBI chr16:28,466,653...28,492,082
Ensembl chr16:28,456,371...28,492,098
Ensembl chr16:28,456,371...28,492,098
JBrowse link
G PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing IDA (PMID:28779020) UniProt PMID:28779020 NCBI chr 2:208,266,178...208,358,747
Ensembl chr 2:208,266,255...208,358,746
JBrowse link
G PLA2G5 phospholipase A2 group V ISS UniProt GO_REF:0000024 NCBI chr 1:20,028,349...20,091,911
Ensembl chr 1:20,028,179...20,091,911
JBrowse link
G RAB20 RAB20, member RAS oncogene family IMP (PMID:21255211) UniProtKB PMID:21255211 NCBI chr13:110,523,066...110,561,722
Ensembl chr13:110,523,066...110,561,722
JBrowse link
G RAB34 RAB34, member RAS oncogene family IMP
IBA
(PMID:21255211)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21255211, PMID:21873635 NCBI chr17:28,714,281...28,718,440
Ensembl chr17:28,714,281...28,718,429
JBrowse link
G RAB39A RAB39A, member RAS oncogene family IMP (PMID:21255211) UniProtKB PMID:21255211 NCBI chr11:107,928,448...107,963,482
Ensembl chr11:107,928,448...107,963,482
JBrowse link
G RAB7A RAB7A, member RAS oncogene family IMP
IBA
(PMID:21255211)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21255211, PMID:21873635 NCBI chr 3:128,726,183...128,814,798
Ensembl chr 3:128,693,669...128,825,942
Ensembl chr 3:128,693,669...128,825,942
Ensembl chr 3:128,693,669...128,825,942
JBrowse link
G RAB7B RAB7B, member RAS oncogene family IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:205,976,740...206,003,470
Ensembl chr 1:205,976,740...206,003,461
JBrowse link
G SYT7 synaptotagmin 7 ISS UniProtKB GO_REF:0000024 NCBI chr11:61,513,714...61,588,404
Ensembl chr11:61,513,714...61,581,148
Ensembl chr11:61,513,714...61,581,148
JBrowse link
G TMEM175 transmembrane protein 175 IEA Ensembl GO_REF:0000107 NCBI chr 4:932,412...958,656
Ensembl chr 4:932,387...958,656
JBrowse link
phagosome-lysosome fusion involved in apoptotic cell clearance term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPG11 SPG11 vesicle trafficking associated, spatacsin IEA Ensembl GO_REF:0000107 NCBI chr15:44,562,696...44,663,678
Ensembl chr15:44,562,696...44,663,678
JBrowse link
positive regulation of lysosomal membrane permeability term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:9038169 RGD:10059368 NCBI chr11:123,057,489...123,062,366
Ensembl chr11:123,057,489...123,063,230
JBrowse link
G MT3 metallothionein 3 ISS UniProtKB GO_REF:0000024 NCBI chr16:56,589,528...56,591,085
Ensembl chr16:56,589,074...56,591,088
JBrowse link
positive regulation of lysosome organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRN granulin precursor IDA (PMID:28073925) UniProt PMID:28073925 NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106
JBrowse link
regulation of lysosomal lumen pH term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRK2 leucine rich repeat kinase 2 IMP (PMID:22012985) ParkinsonsUK-UCL PMID:22012985 NCBI chr12:40,224,890...40,369,285
Ensembl chr12:40,196,744...40,369,285
JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 IDA
IBA
(PMID:31001245)
(PMID:21873635)
UniProt
GO_Central
PMID:21873635, PMID:31001245 NCBI chr  X:30,558,809...30,577,766
Ensembl chr  X:30,558,809...30,577,766
JBrowse link
G TMEM165 transmembrane protein 165 IMP (PMID:23569283) UniProtKB PMID:23569283 NCBI chr 4:55,395,653...55,453,397
Ensembl chr 4:55,395,957...55,453,397
JBrowse link
G TMEM175 transmembrane protein 175 IEA Ensembl GO_REF:0000107 NCBI chr 4:932,412...958,656
Ensembl chr 4:932,387...958,656
JBrowse link
G VPS33A VPS33A core subunit of CORVET and HOPS complexes IMP (PMID:28013294) UniProtKB PMID:28013294 NCBI chr12:122,229,564...122,266,494
Ensembl chr12:122,229,564...122,266,494
JBrowse link
regulation of lysosomal membrane permeability term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LAPTM4B lysosomal protein transmembrane 4 beta IMP (PMID:26280656) UniProtKB PMID:26280656 NCBI chr 8:97,775,788...97,853,013
Ensembl chr 8:97,775,057...97,853,013
JBrowse link
regulation of lysosome organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LAPTM4B lysosomal protein transmembrane 4 beta IMP (PMID:26280656) UniProtKB PMID:26280656 NCBI chr 8:97,775,788...97,853,013
Ensembl chr 8:97,775,057...97,853,013
JBrowse link
G SCARB2 scavenger receptor class B member 2 TAS (PMID:12356916) ParkinsonsUK-UCL PMID:12356916 NCBI chr 4:76,158,737...76,213,824
Ensembl chr 4:76,158,737...76,234,536
JBrowse link
G TREX1 three prime repair exonuclease 1 IEA Ensembl GO_REF:0000107 NCBI chr 3:48,465,830...48,467,645
Ensembl chr 3:48,465,811...48,467,645
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18651
    cellular process 17669
      cellular component organization or biogenesis 7122
        cellular component organization 6931
          organelle organization 4323
            vacuole organization 188
              lytic vacuole organization 75
                lysosome organization 75
                  lysosomal membrane organization + 4
                  negative regulation of lysosome organization 1
                  phagolysosome assembly + 16
                  positive regulation of lysosome organization 1
                  regulation of lysosomal lumen pH + 15
                  regulation of lysosome organization + 5
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.