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ONTOLOGY REPORT - ANNOTATIONS


Term:lysosome organization
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Accession:GO:0007040 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.
Synonyms:exact_synonym: lysosome organisation
 related_synonym: lysosome organization and biogenesis


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lysosome organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP-binding cassette, sub-family A (ABC1), member 1 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
JBrowse link
G Acp2 acid phosphatase 2, lysosomal IMP
IBA
(MGI:MGI:894905|PMID:9228031)
(MGI:MGI:6201960|PMID:21873635)
(MGI:MGI:3522374|PMID:15604265)
MGI
GO_Central
PMID:9228031, PMID:15604265, PMID:21873635 MGI:MGI:3522374, MGI:MGI:6201960, MGI:MGI:894905 NCBI chr 2:91,202,812...91,214,098
Ensembl chr 2:91,202,885...91,214,098
JBrowse link
G Acp4 acid phosphatase 4 IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr 7:44,252,003...44,261,390
Ensembl chr 7:44,252,148...44,257,378
JBrowse link
G Acpp acid phosphatase, prostate IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr 9:104,288,240...104,337,722
Ensembl chr 9:104,288,251...104,337,748
JBrowse link
G Aktip thymoma viral proto-oncogene 1 interacting protein ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 8:91,111,781...91,135,494
Ensembl chr 8:91,111,784...91,199,976
JBrowse link
G Ap3b1 adaptor-related protein complex 3, beta 1 subunit IMP (MGI:MGI:1330543|PMID:9931340), (MGI:MGI:6415001|PMID:30786955) MGI PMID:9931340, PMID:30786955 MGI:MGI:1330543, MGI:MGI:6415001 NCBI chr13:94,358,960...94,566,316
Ensembl chr13:94,358,960...94,566,317
JBrowse link
G Becn1 beclin 1, autophagy related IMP (MGI:MGI:3801567|PMID:18497889) MGI PMID:18497889 MGI:MGI:3801567 NCBI chr11:101,288,258...101,302,286
Ensembl chr11:101,285,952...101,302,286
JBrowse link
G Chmp5 charged multivesicular body protein 5 IMP (MGI:MGI:3622513|PMID:16567502) MGI PMID:16567502 MGI:MGI:3622513 NCBI chr 4:40,948,553...40,965,302
Ensembl chr 4:40,948,407...40,965,303
JBrowse link
G Cln3 ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) IMP
IBA
(MGI:MGI:1343910|PMID:10440905)
(MGI:MGI:6201960|PMID:21873635)
(MGI:MGI:1337525|PMID:10191119), (MGI:MGI:1346962|PMID:10527801)
(MGI:MGI:3527911|PMID:15588329)
MGI
GO_Central
PMID:10191119, PMID:10440905, PMID:10527801, PMID:15588329, PMID:21873635 MGI:MGI:1337525, MGI:MGI:1343910, MGI:MGI:1346962, MGI:MGI:3527911, MGI:MGI:6201960 NCBI chr 7:126,571,207...126,585,817
Ensembl chr 7:126,571,207...126,585,817
JBrowse link
G Cln5 ceroid-lipofuscinosis, neuronal 5 IMP
IBA
(MGI:MGI:3512689|PMID:15459177)
(MGI:MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:15459177, PMID:21873635 MGI:MGI:3512689, MGI:MGI:6201960 NCBI chr14:103,070,216...103,077,630
Ensembl chr14:103,070,216...103,077,628
JBrowse link
G Cln6 ceroid-lipofuscinosis, neuronal 6 IMP
IBA
(MGI:MGI:1203267|PMID:9600738), (MGI:MGI:5751614|PMID:26681805)
(MGI:MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:9600738, PMID:21873635, PMID:26681805 MGI:MGI:1203267, MGI:MGI:5751614, MGI:MGI:6201960 NCBI chr 9:62,838,785...62,852,006
Ensembl chr 9:62,838,785...62,852,006
JBrowse link
G Cln8 CLN8 transmembrane ER and ERGIC protein IMP (MGI:MGI:1333651|PMID:10087069), (MGI:MGI:65559|PMID:8144516), (MGI:MGI:66707|PMID:8160780), (MGI:MGI:71226|PMID:7613514) MGI PMID:7613514, PMID:8144516, PMID:8160780, PMID:10087069 MGI:MGI:1333651, MGI:MGI:65559, MGI:MGI:66707, MGI:MGI:71226 NCBI chr 8:14,881,335...14,901,720
Ensembl chr 8:14,881,335...14,901,720
JBrowse link
G Clvs1 clavesin 1 ISO
IBA
(MGI:MGI:6201960|PMID:21873635) RGD
GO_Central
PMID:21873635 GO_REF:0000096, MGI:MGI:4417868, MGI:MGI:6201960 NCBI chr 4:9,144,745...9,451,691
Ensembl chr 4:9,269,293...9,451,691
JBrowse link
G Clvs2 clavesin 2 IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr10:33,512,286...33,624,684
Ensembl chr10:33,512,286...33,624,769
JBrowse link
G Fam160a2 family with sequence similarity 160, member A2 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 7:105,371,211...105,400,142
Ensembl chr 7:105,371,211...105,400,054
JBrowse link
G Gaa glucosidase, alpha, acid ISO
IMP
(MGI:MGI:1195358|PMID:9384603), (MGI:MGI:1346721|PMID:10547605), (MGI:MGI:2136118|PMID:11328962), (MGI:MGI:3664400|PMID:12115977)
(MGI:MGI:1275872|PMID:9668092), (MGI:MGI:3618942|PMID:15169761)
MGI PMID:9384603, PMID:9668092, PMID:10547605, PMID:11328962, PMID:12115977, PMID:15169761 GO_REF:0000096, MGI:MGI:1195358, MGI:MGI:1275872, MGI:MGI:1346721, MGI:MGI:2136118, MGI:MGI:3618942, MGI:MGI:3664400, MGI:MGI:4834177 NCBI chr11:119,267,963...119,285,458
Ensembl chr11:119,267,887...119,285,454
JBrowse link
G Gba glucosidase, beta, acid IMP
ISO
(MGI:MGI:5817293|PMID:27378698) UniProt
MGI
PMID:27378698 GO_REF:0000096, MGI:MGI:4834177, MGI:MGI:5817293 NCBI chr 3:89,202,905...89,208,873
Ensembl chr 3:89,202,928...89,208,966
JBrowse link
G Gnptab N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr10:88,379,134...88,447,324
Ensembl chr10:88,379,132...88,447,329
JBrowse link
G Grn granulin IMP (MGI:MGI:6274951|PMID:27789271) UniProt PMID:27789271 MGI:MGI:6274951 NCBI chr11:102,430,507...102,436,809
Ensembl chr11:102,430,315...102,437,048
JBrowse link
G Hexa hexosaminidase A IMP
IGI
(MGI:MGI:77946|PMID:8747922)
(MGI:MGI:1097747|PMID:9302266), (MGI:MGI:1271008|PMID:9645704), (MGI:MGI:1352198|PMID:10591619), (MGI:MGI:3033296|PMID:14972652)
(MGI:MGI:83770|PMID:8896570), (MGI:MGI:894634|PMID:9184660)
(MGI:MGI:69059|PMID:7937929), (MGI:MGI:86923|PMID:9103204)
MGI PMID:7937929, PMID:8747922, PMID:8896570, PMID:9103204, PMID:9184660, PMID:9302266, PMID:9645704, PMID:10591619, PMID:14972652 MGI:MGI:1097747, MGI:MGI:1271008, MGI:MGI:1352198, MGI:MGI:3033296, MGI:MGI:69059, MGI:MGI:77946, MGI:MGI:83770, MGI:MGI:86923, MGI:MGI:894634 NCBI chr 9:59,539,540...59,565,109
Ensembl chr 9:59,539,540...59,565,109
JBrowse link
G Hexb hexosaminidase B IMP
IGI
(MGI:MGI:1271008|PMID:9645704), (MGI:MGI:78473|PMID:8789434)
(MGI:MGI:83770|PMID:8896570), (MGI:MGI:894634|PMID:9184660)
MGI PMID:8789434, PMID:8896570, PMID:9184660, PMID:9645704 MGI:MGI:1271008, MGI:MGI:78473, MGI:MGI:83770, MGI:MGI:894634 NCBI chr13:97,176,331...97,198,357
Ensembl chr13:97,176,331...97,198,357
JBrowse link
G Hook1 hook microtubule tethering protein 1 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 4:95,967,181...96,025,412
Ensembl chr 4:95,967,240...96,025,413
JBrowse link
G Hook2 hook microtubule tethering protein 2 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 8:84,988,776...85,003,352
Ensembl chr 8:84,990,603...85,003,349
JBrowse link
G Hook3 hook microtubule tethering protein 3 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 8:26,021,421...26,119,618
Ensembl chr 8:26,021,421...26,119,224
JBrowse link
G Hps1 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 IMP (MGI:MGI:6415001|PMID:30786955) MGI PMID:30786955 MGI:MGI:6415001 NCBI chr19:42,755,190...42,780,015
Ensembl chr19:42,755,105...42,779,978
JBrowse link
G Hps4 HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 ISS
ISO
(MGI:MGI:3687925|PMID:12663659) UniProtKB
MGI
PMID:12663659 GO_REF:0000096, MGI:MGI:3687925, MGI:MGI:4834177 NCBI chr 5:112,342,983...112,378,424
Ensembl chr 5:112,343,083...112,378,414
JBrowse link
G Idua iduronidase, alpha-L IMP (MGI:MGI:86916|PMID:9097952)
(MGI:MGI:4414887|PMID:19751987)
MGI PMID:9097952, PMID:19751987 MGI:MGI:4414887, MGI:MGI:86916 NCBI chr 5:108,660,331...108,685,446
Ensembl chr 5:108,660,331...108,684,557
JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 IMP (MGI:MGI:4887551|PMID:19177150) UniProtKB PMID:19177150 MGI:MGI:4887551 NCBI chr 7:101,905,837...101,911,903
Ensembl chr 7:101,905,904...101,926,675
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr15:91,672,791...91,816,124
Ensembl chr15:91,673,175...91,816,120
JBrowse link
G Lyst lysosomal trafficking regulator IMP (MGI:MGI:1099544|PMID:9368050)
(MGI:MGI:53816|PMID:4697831), (MGI:MGI:53992|PMID:1113502), (MGI:MGI:55104|PMID:6170520), (MGI:MGI:56449|PMID:4031470)
MGI PMID:1113502, PMID:4031470, PMID:4697831, PMID:6170520, PMID:9368050 MGI:MGI:1099544, MGI:MGI:53816, MGI:MGI:53992, MGI:MGI:55104, MGI:MGI:56449 NCBI chr13:13,590,311...13,778,803
Ensembl chr13:13,590,397...13,778,803
JBrowse link
G Mbtps1 membrane-bound transcription factor peptidase, site 1 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 8:119,508,151...119,558,864
Ensembl chr 8:119,508,156...119,558,735
JBrowse link
G Mfsd8 major facilitator superfamily domain containing 8 IMP (MGI:MGI:5575728|PMID:24423645)
(MGI:MGI:5751614|PMID:26681805)
MGI PMID:24423645, PMID:26681805 MGI:MGI:5575728, MGI:MGI:5751614 NCBI chr 3:40,818,065...40,846,880
Ensembl chr 3:40,818,103...40,846,886
JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 4:148,448,582...148,557,685
Ensembl chr 4:148,448,611...148,557,683
JBrowse link
G Myo7a myosin VIIA ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 7:98,051,054...98,119,522
Ensembl chr 7:98,051,060...98,119,524
JBrowse link
G Naglu alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB) IMP (MGI:MGI:3769195|PMID:17712420) MGI PMID:17712420 MGI:MGI:3769195 NCBI chr11:101,070,090...101,077,672
Ensembl chr11:101,070,012...101,077,672
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 IMP (MGI:MGI:3612221|PMID:16368712)
(MGI:MGI:3654230|PMID:16542649)
MGI PMID:16368712, PMID:16542649 MGI:MGI:3612221, MGI:MGI:3654230 NCBI chr 4:122,836,077...122,859,175
Ensembl chr 4:122,836,242...122,859,175
JBrowse link
G Snapin SNAP-associated protein IMP
IBA
(MGI:MGI:4879078|PMID:20920792)
(MGI:MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:20920792, PMID:21873635 MGI:MGI:4879078, MGI:MGI:6201960 NCBI chr 3:90,488,026...90,491,013
Ensembl chr 3:90,488,026...90,491,033
JBrowse link
G Spg11 SPG11, spatacsin vesicle trafficking associated IMP (MGI:MGI:5749311|PMID:26284655) MGI PMID:26284655 MGI:MGI:5749311 NCBI chr 2:122,053,526...122,119,434
Ensembl chr 2:122,053,520...122,118,386
JBrowse link
G Tfeb transcription factor EB ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr17:47,737,037...47,792,416
Ensembl chr17:47,737,030...47,792,419
JBrowse link
G Tmem106b transmembrane protein 106B IMP
IBA
(MGI:MGI:5588048|PMID:25066864)
(MGI:MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:21873635, PMID:25066864 MGI:MGI:5588048, MGI:MGI:6201960 NCBI chr 6:13,069,759...13,089,269
Ensembl chr 6:13,069,759...13,089,269
JBrowse link
G Tpcn2 two pore segment channel 2 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 7:145,181,633...145,284,011
Ensembl chr 7:145,186,524...145,284,011
JBrowse link
G Tpp1 tripeptidyl peptidase I IMP (MGI:MGI:3522013|PMID:15483130) MGI PMID:15483130 MGI:MGI:3522013 NCBI chr 7:105,744,811...105,752,282
Ensembl chr 7:105,744,811...105,752,235
JBrowse link
G Vps18 VPS18 CORVET/HOPS core subunit ISO
IBA
(MGI:MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096, MGI:MGI:4834177, MGI:MGI:6201960 NCBI chr 2:119,288,742...119,298,453
Ensembl chr 2:119,288,740...119,298,453
JBrowse link
G Vps35 VPS35 retromer complex component IMP (MGI:MGI:5694519|PMID:26203154) ParkinsonsUK-UCL PMID:26203154 MGI:MGI:5694519 NCBI chr 8:85,260,385...85,299,517
Ensembl chr 8:85,260,392...85,299,802
JBrowse link
G Washc5 WASH complex subunit 5 IMP
ISO
(MGI:MGI:6199426|PMID:30061306) MGI PMID:30061306 MGI:MGI:6199426 NCBI chr15:59,331,863...59,374,194
Ensembl chr15:59,331,997...59,374,167
JBrowse link
G Zkscan3 zinc finger with KRAB and SCAN domains 3 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr13:21,387,004...21,402,755
Ensembl chr13:21,387,003...21,402,755
JBrowse link
lysosomal lumen acidification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase, H+ transporting, lysosomal accessory protein 2 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr  X:12,587,759...12,617,051
Ensembl chr  X:12,587,801...12,617,049
JBrowse link
G Atp6v0c ATPase, H+ transporting, lysosomal V0 subunit C TAS (MGI:MGI:2149889|PMID:11441017) MGI PMID:11441017 MGI:MGI:2149889 NCBI chr17:24,163,865...24,169,678
Ensembl chr17:24,163,866...24,169,702
JBrowse link
G Ccdc115 coiled-coil domain containing 115 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 1:34,436,670...34,439,672
Ensembl chr 1:34,436,670...34,439,672
JBrowse link
G Cln3 ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) ISO
IBA
(MGI:MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096, MGI:MGI:4834177, MGI:MGI:6201960 NCBI chr 7:126,571,207...126,585,817
Ensembl chr 7:126,571,207...126,585,817
JBrowse link
G Cln5 ceroid-lipofuscinosis, neuronal 5 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr14:103,070,216...103,077,630
Ensembl chr14:103,070,216...103,077,628
JBrowse link
G Cln6 ceroid-lipofuscinosis, neuronal 6 ISS
ISO
(MGI:MGI:2157193|PMID:11727201) UniProtKB
MGI
PMID:11727201 GO_REF:0000096, MGI:MGI:2157193, MGI:MGI:4834177 NCBI chr 9:62,838,785...62,852,006
Ensembl chr 9:62,838,785...62,852,006
JBrowse link
G Grn granulin ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr11:102,430,507...102,436,809
Ensembl chr11:102,430,315...102,437,048
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 4:122,836,077...122,859,175
Ensembl chr 4:122,836,242...122,859,175
JBrowse link
G Snapin SNAP-associated protein IMP (MGI:MGI:4879078|PMID:20920792) MGI PMID:20920792 MGI:MGI:4879078 NCBI chr 3:90,488,026...90,491,013
Ensembl chr 3:90,488,026...90,491,033
JBrowse link
G Tmem199 transmembrane protein 199 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr11:78,507,055...78,512,168
Ensembl chr11:78,507,055...78,512,172
JBrowse link
G Tmem9 transmembrane protein 9 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 1:136,008,219...136,035,030
Ensembl chr 1:136,008,150...136,035,342
JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 7:126,571,207...126,585,817
Ensembl chr 7:126,571,207...126,585,817
JBrowse link
lysosomal membrane organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arf1 ADP-ribosylation factor 1 ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr11:59,211,412...59,228,267
Ensembl chr11:59,211,412...59,228,270
JBrowse link
negative regulation of lysosome organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn1 beclin 1, autophagy related ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr11:101,288,258...101,302,286
Ensembl chr11:101,285,952...101,302,286
JBrowse link
phagolysosome assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coro1a coronin, actin binding protein 1A ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 7:126,699,774...126,704,816
Ensembl chr 7:126,699,773...126,707,787
JBrowse link
G Myo7a myosin VIIA IMP (MGI:MGI:2662763|PMID:12743369) MGI PMID:12743369 MGI:MGI:2662763 NCBI chr 7:98,051,054...98,119,522
Ensembl chr 7:98,051,060...98,119,524
JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 IMP (MGI:MGI:3699774|PMID:11544318) MGI PMID:11544318 MGI:MGI:3699774 NCBI chr 5:122,643,927...122,692,336
Ensembl chr 5:122,643,911...122,691,432
JBrowse link
G Srpx sushi-repeat-containing protein IMP (MGI:MGI:3852261|PMID:19368996) MGI PMID:19368996 MGI:MGI:3852261 NCBI chr  X:10,037,977...10,117,640
Ensembl chr  X:10,037,977...10,117,709
JBrowse link
phagolysosome assembly involved in apoptotic cell clearance term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab14 RAB14, member RAS oncogene family IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr 2:35,180,205...35,201,120
Ensembl chr 2:35,180,205...35,201,120
JBrowse link
phagosome-lysosome docking term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) IMP (MGI:MGI:5698740|PMID:26450516) UniProt PMID:26450516 MGI:MGI:5698740 NCBI chr 7:126,571,207...126,585,817
Ensembl chr 7:126,571,207...126,585,817
JBrowse link
phagosome-lysosome fusion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) IMP (MGI:MGI:5698740|PMID:26450516) UniProt PMID:26450516 MGI:MGI:5698740 NCBI chr 7:126,571,207...126,585,817
Ensembl chr 7:126,571,207...126,585,817
JBrowse link
G Pikfyve phosphoinositide kinase, FYVE type zinc finger containing ISO
IDA
(MGI:MGI:6103777|PMID:28779020) MGI
UniProt
PMID:28779020 GO_REF:0000096, MGI:MGI:4834177, MGI:MGI:6103777 NCBI chr 1:65,186,640...65,278,696
Ensembl chr 1:65,186,683...65,278,695
JBrowse link
G Pla2g5 phospholipase A2, group V IMP (MGI:MGI:3841317|PMID:19342668) UniProt PMID:19342668 MGI:MGI:3841317 NCBI chr 4:138,799,247...138,863,562
Ensembl chr 4:138,799,244...138,863,482
JBrowse link
G Rab20 RAB20, member RAS oncogene family ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 8:11,453,390...11,478,640
Ensembl chr 8:11,453,518...11,478,710
JBrowse link
G Rab34 RAB34, member RAS oncogene family IMP
IBA
ISO
(MGI:MGI:5467668|PMID:23197834)
(MGI:MGI:6201960|PMID:21873635)
ParkinsonsUK-UCL
GO_Central
MGI
PMID:21873635, PMID:23197834 GO_REF:0000096, MGI:MGI:4834177, MGI:MGI:5467668, MGI:MGI:6201960 NCBI chr11:78,188,427...78,192,193
Ensembl chr11:78,188,430...78,192,193
JBrowse link
G Rab39 RAB39, member RAS oncogene family ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 9:53,684,110...53,706,232
Ensembl chr 9:53,684,110...53,706,232
JBrowse link
G Rab7 RAB7, member RAS oncogene family ISO
IBA
(MGI:MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096, MGI:MGI:4834177, MGI:MGI:6201960 NCBI chr 6:87,999,106...88,045,270
Ensembl chr 6:87,999,106...88,045,270
JBrowse link
G Rab7b RAB7B, member RAS oncogene family IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr 1:131,688,681...131,715,443
Ensembl chr 1:131,688,695...131,715,439
JBrowse link
G Syt7 synaptotagmin VII IMP (MGI:MGI:3690533|PMID:16982801) UniProtKB PMID:16982801 MGI:MGI:3690533 NCBI chr19:10,388,802...10,453,181
Ensembl chr19:10,389,090...10,453,180
JBrowse link
G Tmem175 transmembrane protein 175 IMP (MGI:MGI:5693670|PMID:26317472) UniProtKB PMID:26317472 MGI:MGI:5693670 NCBI chr 5:108,629,779...108,647,770
Ensembl chr 5:108,629,770...108,648,782
JBrowse link
phagosome-lysosome fusion involved in apoptotic cell clearance term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spg11 SPG11, spatacsin vesicle trafficking associated IMP (MGI:MGI:5749311|PMID:26284655) MGI PMID:26284655 MGI:MGI:5749311 NCBI chr 2:122,053,526...122,119,434
Ensembl chr 2:122,053,520...122,118,386
JBrowse link
positive regulation of lysosomal membrane permeability term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa8 heat shock protein 8 ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr 9:40,801,276...40,805,202
Ensembl chr 9:40,800,984...40,810,087
JBrowse link
G Mt3 metallothionein 3 IMP (MGI:MGI:4881636|PMID:20544854) UniProtKB PMID:20544854 MGI:MGI:4881636 NCBI chr 8:94,152,607...94,154,148
Ensembl chr 8:94,152,607...94,154,146
JBrowse link
positive regulation of lysosome organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grn granulin IDA
ISO
(MGI:MGI:5905514|PMID:28073925) UniProt
MGI
PMID:28073925 GO_REF:0000096, MGI:MGI:4834177, MGI:MGI:5905514 NCBI chr11:102,430,507...102,436,809
Ensembl chr11:102,430,315...102,437,048
JBrowse link
regulation of lysosomal lumen pH term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gm6377 predicted gene 6377 IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr  X:109,196,756...109,200,445
Ensembl chr  X:109,196,756...109,200,439
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr15:91,672,791...91,816,124
Ensembl chr15:91,673,175...91,816,120
JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 ISO
IBA
(MGI:MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096, MGI:MGI:4834177, MGI:MGI:6201960 NCBI chr  X:85,776,968...85,891,499
Ensembl chr  X:85,870,354...85,891,499
JBrowse link
G Tmem165 transmembrane protein 165 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 5:76,183,880...76,209,244
Ensembl chr 5:76,183,880...76,209,245
JBrowse link
G Tmem175 transmembrane protein 175 IMP (MGI:MGI:5693670|PMID:26317472) UniProtKB PMID:26317472 MGI:MGI:5693670 NCBI chr 5:108,629,779...108,647,770
Ensembl chr 5:108,629,770...108,648,782
JBrowse link
G Vps33a VPS33A CORVET/HOPS core subunit ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 5:123,528,757...123,573,043
Ensembl chr 5:123,528,659...123,573,038
JBrowse link
regulation of lysosomal membrane permeability term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Laptm4b lysosomal-associated protein transmembrane 4B ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr15:34,238,026...34,284,295
Ensembl chr15:34,238,028...34,284,302
JBrowse link
regulation of lysosome organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Laptm4b lysosomal-associated protein transmembrane 4B ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr15:34,238,026...34,284,295
Ensembl chr15:34,238,028...34,284,302
JBrowse link
G Trex1 three prime repair exonuclease 1 IMP (MGI:MGI:5460923|PMID:23160154) MGI PMID:23160154 MGI:MGI:5460923 NCBI chr 9:109,057,932...109,059,723
Ensembl chr 9:109,057,933...109,059,734
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23360
    cellular process 17360
      cellular component organization or biogenesis 6385
        cellular component organization 6197
          organelle organization 3829
            vacuole organization 177
              lytic vacuole organization 73
                lysosome organization 73
                  lysosomal membrane organization + 4
                  negative regulation of lysosome organization 1
                  phagolysosome assembly + 16
                  positive regulation of lysosome organization 1
                  regulation of lysosomal lumen pH + 17
                  regulation of lysosome organization + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.