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ONTOLOGY REPORT - ANNOTATIONS


Term:lysosome organization
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Accession:GO:0007040 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.
Synonyms:exact_synonym: lysosome organisation
 related_synonym: lysosome organization and biogenesis


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lysosome organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07008608.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 2:66,600,151...66,608,324 JBrowse link
G AABR07019209.2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr15:93,634,820...93,639,250 JBrowse link
G AABR07028902.1 IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr17:90,370,882...90,522,091 JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 ISO (PMID:15163665) RGD PMID:15163665 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Acp2 acid phosphatase 2, lysosomal IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
MGI:MGI:2180084|MGI:MGI:3574793 (MGI:MGI:3522374|PMID:15604265), (MGI:MGI:894905|PMID:9228031)
Ensembl
RGD
PMID:9228031, PMID:15604265, PMID:21873635 GO_REF:0000107, MGI:MGI:3522374, MGI:MGI:894905, RGD:13792537 NCBI chr 3:80,020,346...80,030,365
Ensembl chr 3:80,021,440...80,030,363
JBrowse link
G Acp3 acid phosphatase 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:112,838,574...112,884,062
Ensembl chr 8:112,834,707...112,884,077
JBrowse link
G Acp4 acid phosphatase 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:100,226,311...100,234,536
Ensembl chr 1:100,227,157...100,234,040
JBrowse link
G Aktip AKT interacting protein ISO
ISS
(PMID:18799622)
GO_REF:0000024
RGD
UniProt
PMID:18799622 GO_REF:0000024 NCBI chr19:17,290,048...17,300,054
Ensembl chr19:17,290,178...17,300,050
JBrowse link
G Ap3b1 adaptor related protein complex 3 subunit beta 1 ISO (MGI:MGI:1330543|PMID:9931340), (MGI:MGI:6415001|PMID:30786955) RGD PMID:9931340, PMID:30786955 MGI:MGI:1330543, MGI:MGI:6415001 NCBI chr 2:24,022,815...24,227,522
Ensembl chr 2:24,024,791...24,226,224
JBrowse link
G Becn1 beclin 1 ISO MGI:MGI:2683696 (MGI:MGI:3801567|PMID:18497889) RGD PMID:18497889 MGI:MGI:3801567 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Chmp5 charged multivesicular body protein 5 ISO MGI:MGI:3626293 (MGI:MGI:3622513|PMID:16567502) RGD PMID:16567502 MGI:MGI:3622513 NCBI chr 5:57,267,312...57,284,455
Ensembl chr 5:57,267,312...57,284,448
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO
IBA
MGI:MGI:1933976|MGI:MGI:2388887|MGI:MGI:3623134 (MGI:MGI:1337525|PMID:10191119), (MGI:MGI:1343910|PMID:10440905), (MGI:MGI:1346962|PMID:10527801), (MGI:MGI:3527911|PMID:15588329)
PMID:21873635
RGD PMID:10191119, PMID:10440905, PMID:10527801, PMID:15588329, PMID:21873635 MGI:MGI:1337525, MGI:MGI:1343910, MGI:MGI:1346962, MGI:MGI:3527911, RGD:13792537 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
G Cln5 CLN5, intracellular trafficking protein ISO MGI:MGI:3521802 (MGI:MGI:3512689|PMID:15459177) RGD PMID:15459177 MGI:MGI:3512689 NCBI chr15:93,634,815...93,644,146 JBrowse link
G Cln6 CLN6, transmembrane ER protein ISO
IBA
MGI:MGI:2159328 (MGI:MGI:1203267|PMID:9600738), (MGI:MGI:5751614|PMID:26681805)
PMID:21873635
RGD PMID:9600738, PMID:26681805, PMID:21873635 MGI:MGI:1203267, MGI:MGI:5751614, RGD:13792537 NCBI chr 8:67,733,215...67,748,170
Ensembl chr 8:67,733,215...67,748,172
JBrowse link
G Cln8 CLN8, transmembrane ER and ERGIC protein ISO MGI:MGI:1856959 (MGI:MGI:1333651|PMID:10087069), (MGI:MGI:65559|PMID:8144516), (MGI:MGI:66707|PMID:8160780), (MGI:MGI:71226|PMID:7613514) RGD PMID:7613514, PMID:8144516, PMID:8160780, PMID:10087069 MGI:MGI:1333651, MGI:MGI:65559, MGI:MGI:66707, MGI:MGI:71226 NCBI chr16:79,828,321...79,838,212
Ensembl chr16:79,828,324...79,838,212
JBrowse link
G Clvs1 clavesin 1 IEA
IBA
IMP
GO_REF:0000002
PMID:21873635
PMID:19651769
InterPro PMID:21873635, PMID:19651769 GO_REF:0000002, RGD:13792537, RGD:8553526 NCBI chr 5:22,380,318...22,580,391
Ensembl chr 5:22,380,334...22,578,297
JBrowse link
G Clvs2 clavesin 2 IMP
IBA
PMID:19651769
PMID:21873635
UniProt
GO_Central
PMID:19651769, PMID:21873635 RGD:8553526, RGD:13792537 NCBI chr 1:25,173,089...25,217,625
Ensembl chr 1:25,173,242...25,296,927
JBrowse link
G Fam160a2 family with sequence similarity 160, member A2 ISO
ISS
(PMID:18799622)
GO_REF:0000024
RGD
UniProt
PMID:18799622 GO_REF:0000024 NCBI chr 1:170,216,505...170,238,898
Ensembl chr 1:170,212,817...170,238,890
JBrowse link
G Gaa glucosidase, alpha, acid ISO
IEA
(PMID:7717400)
MGI:MGI:2148550|MGI:MGI:2179961 (MGI:MGI:1195358|PMID:9384603), (MGI:MGI:1275872|PMID:9668092), (MGI:MGI:1346721|PMID:10547605), (MGI:MGI:2136118|PMID:11328962), (MGI:MGI:3618942|PMID:15169761), (MGI:MGI:3664400|PMID:12115977)
GO_REF:0000107
RGD
Ensembl
PMID:7717400, PMID:9384603, PMID:9668092, PMID:10547605, PMID:11328962, PMID:12115977, PMID:15169761 GO_REF:0000107, MGI:MGI:1195358, MGI:MGI:1275872, MGI:MGI:1346721, MGI:MGI:2136118, MGI:MGI:3618942, MGI:MGI:3664400 NCBI chr10:108,395,873...108,412,999
Ensembl chr10:108,395,860...108,413,059
JBrowse link
G Gba glucosylceramidase beta ISO (PMID:27378698)
(MGI:MGI:5817293|PMID:27378698)
RGD PMID:27378698 MGI:MGI:5817293 NCBI chr 2:188,511,781...188,522,602
Ensembl chr 2:188,516,582...188,522,601
JBrowse link
G Gnptab N-acetylglucosamine-1-phosphate transferase subunits alpha and beta ISO (PMID:21719679) RGD PMID:21719679 NCBI chr 7:28,956,363...29,023,232
Ensembl chr 7:28,956,512...29,022,868
JBrowse link
G Grn granulin precursor ISS
ISO
GO_REF:0000024
(MGI:MGI:6274951|PMID:27789271)
UniProt
RGD
PMID:27789271 GO_REF:0000024, MGI:MGI:6274951 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Hexa hexosaminidase subunit alpha ISO MGI:MGI:1857181|MGI:MGI:2429698|MGI:MGI:3581540|MGI:MGI:96074 (MGI:MGI:1097747|PMID:9302266), (MGI:MGI:1271008|PMID:9645704), (MGI:MGI:1352198|PMID:10591619), (MGI:MGI:3033296|PMID:14972652), (MGI:MGI:69059|PMID:7937929), (MGI:MGI:77946|PMID:8747922), (MGI:MGI:83770|PMID:8896570), (MGI:MGI:86923|PMID:9103204), (MGI:MGI:894634|PMID:9184660) RGD PMID:7937929, PMID:8747922, PMID:8896570, PMID:9103204, PMID:9184660, PMID:9302266, PMID:9645704, PMID:10591619, PMID:14972652 MGI:MGI:1097747, MGI:MGI:1271008, MGI:MGI:1352198, MGI:MGI:3033296, MGI:MGI:69059, MGI:MGI:77946, MGI:MGI:83770, MGI:MGI:86923, MGI:MGI:894634 NCBI chr 8:64,325,435...64,350,775
Ensembl chr 8:64,325,435...64,350,773
JBrowse link
G Hexb hexosaminidase subunit beta ISO
IEA
MGI:MGI:2429701|MGI:MGI:96073 (MGI:MGI:1271008|PMID:9645704), (MGI:MGI:78473|PMID:8789434), (MGI:MGI:83770|PMID:8896570), (MGI:MGI:894634|PMID:9184660)
GO_REF:0000107
RGD
Ensembl
PMID:8789434, PMID:8896570, PMID:9184660, PMID:9645704 GO_REF:0000107, MGI:MGI:1271008, MGI:MGI:78473, MGI:MGI:83770, MGI:MGI:894634 NCBI chr 2:27,983,925...28,003,260
Ensembl chr 2:27,984,117...28,003,186
JBrowse link
G Hook1 hook microtubule-tethering protein 1 ISO (PMID:18799622) RGD PMID:18799622 NCBI chr 5:114,940,053...115,000,691
Ensembl chr 5:114,940,053...115,000,691
JBrowse link
G Hook2 hook microtubule-tethering protein 2 ISO (PMID:18799622) RGD PMID:18799622 NCBI chr19:26,106,713...26,119,353
Ensembl chr19:26,106,838...26,119,352
JBrowse link
G Hook3 hook microtubule-tethering protein 3 ISO (PMID:18799622) RGD PMID:18799622 NCBI chr16:70,710,347...70,818,789 JBrowse link
G Hps1 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 ISO (MGI:MGI:6415001|PMID:30786955) RGD PMID:30786955 MGI:MGI:6415001 NCBI chr 1:261,989,178...262,015,282
Ensembl chr 1:261,989,178...262,015,153
JBrowse link
G Hps4 HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 ISO (PMID:12663659) RGD PMID:12663659 NCBI chr12:50,285,239...50,315,893
Ensembl chr12:50,285,278...50,314,406
JBrowse link
G Idua alpha-L-iduronidase ISO MGI:MGI:2176236|MGI:MGI:4415188 (MGI:MGI:4414887|PMID:19751987), (MGI:MGI:86916|PMID:9097952) RGD PMID:9097952, PMID:19751987 MGI:MGI:4414887, MGI:MGI:86916 NCBI chr14:2,041,828...2,056,762
Ensembl chr14:2,042,411...2,056,762
JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 ISO
ISS
(MGI:MGI:4887551|PMID:19177150)
GO_REF:0000024
RGD
UniProt
PMID:19177150 GO_REF:0000024, MGI:MGI:4887551 NCBI chr 1:166,991,474...166,997,045
Ensembl chr 1:166,991,474...166,997,045
JBrowse link
G LOC100361543 RhoA activator C11orf59-like ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:37,261,428...37,262,470
Ensembl chr 1:166,991,474...166,997,045
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 ISO (PMID:25416817) RGD PMID:25416817 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584
JBrowse link
G Lyst lysosomal trafficking regulator ISO MGI:MGI:1855968|MGI:MGI:1855969 (MGI:MGI:1099544|PMID:9368050), (MGI:MGI:53816|PMID:4697831), (MGI:MGI:53992|PMID:1113502), (MGI:MGI:55104|PMID:6170520), (MGI:MGI:56449|PMID:4031470) RGD PMID:1113502, PMID:4031470, PMID:4697831, PMID:6170520, PMID:9368050 MGI:MGI:1099544, MGI:MGI:53816, MGI:MGI:53992, MGI:MGI:55104, MGI:MGI:56449 NCBI chr17:90,323,055...90,522,091 JBrowse link
G Mbtps1 membrane-bound transcription factor peptidase, site 1 ISO
ISS
(PMID:21719679)
GO_REF:0000024
RGD
UniProt
PMID:21719679 GO_REF:0000024 NCBI chr19:52,146,507...52,206,310
Ensembl chr19:52,146,808...52,206,310
JBrowse link
G Mfsd8 major facilitator superfamily domain containing 8 ISO MGI:MGI:4456699 (MGI:MGI:5575728|PMID:24423645), (MGI:MGI:5751614|PMID:26681805) RGD PMID:24423645, PMID:26681805 MGI:MGI:5575728, MGI:MGI:5751614 NCBI chr 2:127,706,618...127,784,129
Ensembl chr 2:127,699,761...127,781,003
JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO
ISS
(PMID:22692423)
GO_REF:0000024
RGD
UniProt
PMID:22692423 GO_REF:0000024 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Myo7a myosin VIIA ISO
ISS
(PMID:16001398)
GO_REF:0000024
RGD
UniProt
PMID:16001398 GO_REF:0000024 NCBI chr 1:163,001,313...163,071,545
Ensembl chr 1:163,001,875...163,071,508
JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase ISO MGI:MGI:1934018 (MGI:MGI:3769195|PMID:17712420) RGD PMID:17712420 MGI:MGI:3769195 NCBI chr10:88,979,363...88,986,879
Ensembl chr10:88,979,383...88,986,867
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 ISO MGI:MGI:2176390|MGI:MGI:3527191 (MGI:MGI:3612221|PMID:16368712), (MGI:MGI:3654230|PMID:16542649) RGD PMID:16368712, PMID:16542649 MGI:MGI:3612221, MGI:MGI:3654230 NCBI chr 5:140,538,260...140,558,163
Ensembl chr 5:140,538,260...140,558,162
JBrowse link
G Snapin SNAP-associated protein ISO
IBA
MGI:MGI:3608768 (MGI:MGI:4879078|PMID:20920792)
PMID:21873635
RGD PMID:20920792, PMID:21873635 MGI:MGI:4879078, RGD:13792537 NCBI chr 2:189,878,159...189,880,743
Ensembl chr 2:189,878,168...189,880,743
JBrowse link
G Spg11 SPG11 vesicle trafficking associated, spatacsin ISO MGI:MGI:4377985 (MGI:MGI:5749311|PMID:26284655) RGD PMID:26284655 MGI:MGI:5749311 NCBI chr 3:113,999,600...114,064,438
Ensembl chr 3:113,999,719...114,065,170
JBrowse link
G Tfeb transcription factor EB ISO (PMID:22692423), (PMID:23434374) RGD PMID:22692423, PMID:23434374 NCBI chr 9:15,208,141...15,264,101
Ensembl chr 9:15,207,822...15,214,596
JBrowse link
G Tmem106b transmembrane protein 106B ISO
IBA
(MGI:MGI:5588048|PMID:25066864)
PMID:21873635
RGD PMID:25066864, PMID:21873635 MGI:MGI:5588048, RGD:13792537 NCBI chr 4:39,517,679...39,534,491
Ensembl chr 4:39,517,548...39,535,169
JBrowse link
G Tpcn2 two pore segment channel 2 ISO UniProtKB:Q8NHX9 (PMID:25416817) RGD PMID:25416817 NCBI chr 1:218,419,182...218,448,902
Ensembl chr 1:218,419,184...218,448,877
JBrowse link
G Tpp1 tripeptidyl peptidase 1 ISO
IEA
MGI:MGI:3521972 (MGI:MGI:3522013|PMID:15483130)
GO_REF:0000107
RGD
Ensembl
PMID:15483130 GO_REF:0000107, MGI:MGI:3522013 NCBI chr 1:170,588,036...170,594,159
Ensembl chr 1:170,588,035...170,594,168
JBrowse link
G Vps18 VPS18 core subunit of CORVET and HOPS complexes ISO
IBA
(PMID:18799622)
PMID:21873635
RGD PMID:18799622, PMID:21873635 RGD:13792537 NCBI chr 3:111,097,352...111,108,206
Ensembl chr 3:111,097,326...111,108,295
JBrowse link
G Vps35 VPS35 retromer complex component ISO (MGI:MGI:5694519|PMID:26203154) RGD PMID:26203154 MGI:MGI:5694519 NCBI chr19:27,464,937...27,500,636
Ensembl chr19:27,464,937...27,500,636
JBrowse link
G Washc5 WASH complex subunit 5 ISO MGI:MGI:6246601 (MGI:MGI:6199426|PMID:30061306) RGD PMID:30061306 MGI:MGI:6199426 NCBI chr 7:99,625,379...99,677,237
Ensembl chr 7:99,625,619...99,677,268
JBrowse link
G Zkscan3 zinc finger with KRAB and SCAN domains 3 ISO (PMID:23434374) RGD PMID:23434374 NCBI chr17:45,247,724...45,263,422
Ensembl chr17:45,247,776...45,263,418
JBrowse link
lysosomal lumen acidification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase H+ transporting accessory protein 2 ISO
ISS
(PMID:32276428)
GO_REF:0000024
RGD
UniProt
PMID:32276428 GO_REF:0000024 NCBI chr  X:11,137,889...11,164,854
Ensembl chr  X:11,136,939...11,164,915
JBrowse link
G Ccdc115 coiled-coil domain containing 115 ISO (PMID:28296633) RGD PMID:28296633 NCBI chr 9:37,774,876...37,778,839
Ensembl chr 9:37,775,311...37,779,967
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO
IBA
ISS
(PMID:11722572)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:11722572, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
G Cln5 CLN5, intracellular trafficking protein ISO (PMID:11722572) RGD PMID:11722572 NCBI chr15:93,634,815...93,644,146 JBrowse link
G Cln6 CLN6, transmembrane ER protein ISO (PMID:11722572) RGD PMID:11722572 NCBI chr 8:67,733,215...67,748,170
Ensembl chr 8:67,733,215...67,748,172
JBrowse link
G Grn granulin precursor ISS
ISO
IEA
GO_REF:0000024
(PMID:28073925)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:28073925 GO_REF:0000024, GO_REF:0000107 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 ISO
ISS
(PMID:11722572)
PMID:8895569
RGD PMID:11722572, PMID:8895569 RGD:8553248 NCBI chr 5:140,538,260...140,558,163
Ensembl chr 5:140,538,260...140,558,162
JBrowse link
G Snapin SNAP-associated protein ISO MGI:MGI:3608768 (MGI:MGI:4879078|PMID:20920792) RGD PMID:20920792 MGI:MGI:4879078 NCBI chr 2:189,878,159...189,880,743
Ensembl chr 2:189,878,168...189,880,743
JBrowse link
G Tmem199 transmembrane protein 199 ISO
ISS
(PMID:28296633)
GO_REF:0000024
RGD
UniProt
PMID:28296633 GO_REF:0000024 NCBI chr10:65,775,721...65,780,293
Ensembl chr10:65,775,715...65,780,349
JBrowse link
G Tmem9 transmembrane protein 9 ISO (PMID:30374053) RGD PMID:30374053 NCBI chr13:52,854,031...52,871,300
Ensembl chr13:52,854,031...52,871,297
JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO
ISS
(PMID:10924275)
GO_REF:0000024
RGD
UniProt
PMID:10924275 GO_REF:0000024 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
lysosomal membrane organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arf1 ADP-ribosylation factor 1 IDA RGD PMID:9538255 RGD:9684948 NCBI chr10:45,562,700...45,579,214
Ensembl chr10:45,563,547...45,579,029
JBrowse link
negative regulation of lysosome organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn1 beclin 1 IMP RGD PMID:25561470 RGD:11561937 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
phagolysosome assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coro1a coronin 1A ISO (PMID:12132654) RGD PMID:12132654 NCBI chr 1:198,123,883...198,128,890
Ensembl chr 1:198,123,884...198,128,857
JBrowse link
G Myo7a myosin VIIA ISO MGI:MGI:2155422 (MGI:MGI:2662763|PMID:12743369) RGD PMID:12743369 MGI:MGI:2662763 NCBI chr 1:163,001,313...163,071,545
Ensembl chr 1:163,001,875...163,071,508
JBrowse link
G P2rx7 purinergic receptor P2X 7 ISO MGI:MGI:3606250 (MGI:MGI:3699774|PMID:11544318) RGD PMID:11544318 MGI:MGI:3699774 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G Srpx sushi-repeat-containing protein, X-linked ISO MGI:MGI:3706175 (MGI:MGI:3852261|PMID:19368996) RGD PMID:19368996 MGI:MGI:3852261 NCBI chr  X:14,146,618...14,220,756
Ensembl chr  X:14,150,038...14,220,662
JBrowse link
phagolysosome assembly involved in apoptotic cell clearance term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab14 RAB14, member RAS oncogene family IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:14,373,270...14,395,357
Ensembl chr 3:14,373,275...14,395,362
JBrowse link
phagosome-lysosome docking term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO (MGI:MGI:5698740|PMID:26450516) RGD PMID:26450516 MGI:MGI:5698740 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
phagosome-lysosome fusion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07037545.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr  X:23,416,395...23,417,122 JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO (MGI:MGI:5698740|PMID:26450516) RGD PMID:26450516 MGI:MGI:5698740 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
G Pikfyve phosphoinositide kinase, FYVE-type zinc finger containing ISO
IEA
(PMID:28779020)
(MGI:MGI:6103777|PMID:28779020)
GO_REF:0000107
RGD
Ensembl
PMID:28779020 GO_REF:0000107, MGI:MGI:6103777 NCBI chr 9:71,911,744...72,005,816
Ensembl chr 9:71,915,421...72,005,838
JBrowse link
G Pla2g5 phospholipase A2, group V ISS
ISO
GO_REF:0000024
(MGI:MGI:3841317|PMID:19342668)
UniProt
RGD
PMID:19342668 GO_REF:0000024, MGI:MGI:3841317 NCBI chr 5:157,247,601...157,268,968
Ensembl chr 5:157,247,781...157,268,903
JBrowse link
G Rab20 RAB20, member RAS oncogene family ISO (PMID:21255211) RGD PMID:21255211 NCBI chr16:83,358,116...83,382,326
Ensembl chr16:83,358,116...83,382,326
JBrowse link
G Rab34 RAB34, member RAS oncogene family ISO
IBA
ISS
(MGI:MGI:5467668|PMID:23197834)
PMID:21873635
GO_REF:0000024
(PMID:21255211)
RGD
UniProt
PMID:21255211, PMID:23197834, PMID:21873635 GO_REF:0000024, MGI:MGI:5467668, RGD:13792537 NCBI chr10:65,448,111...65,452,178
Ensembl chr10:65,448,950...65,452,177
JBrowse link
G Rab39a RAB39A, member RAS oncogene family ISO (PMID:21255211) RGD PMID:21255211 NCBI chr 8:58,275,984...58,292,995
Ensembl chr 8:58,272,098...58,293,102
JBrowse link
G Rab7a RAB7A, member RAS oncogene family ISO
IBA
ISS
(PMID:21255211)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:21255211, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 4:119,910,461...119,963,065
Ensembl chr 4:119,910,478...119,959,173
JBrowse link
G Rab7b Rab7b, member RAS oncogene family IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:48,456,143...48,483,714
Ensembl chr13:48,455,923...48,482,138
JBrowse link
G Syt7 synaptotagmin 7 ISO
ISS
(MGI:MGI:3690533|PMID:16982801)
GO_REF:0000024
RGD
UniProt
PMID:16982801 GO_REF:0000024, MGI:MGI:3690533 NCBI chr 1:226,435,816...226,498,008
Ensembl chr 1:226,435,979...226,493,377
JBrowse link
G Tmem175 transmembrane protein 175 ISO
ISS
(MGI:MGI:5693670|PMID:26317472)
GO_REF:0000024
RGD
UniProt
PMID:26317472 GO_REF:0000024, MGI:MGI:5693670 NCBI chr14:2,083,745...2,100,006
Ensembl chr14:2,083,712...2,100,005
JBrowse link
phagosome-lysosome fusion involved in apoptotic cell clearance term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spg11 SPG11 vesicle trafficking associated, spatacsin ISO MGI:MGI:4377985 (MGI:MGI:5749311|PMID:26284655) RGD PMID:26284655 MGI:MGI:5749311 NCBI chr 3:113,999,600...114,064,438
Ensembl chr 3:113,999,719...114,065,170
JBrowse link
positive regulation of lysosomal membrane permeability term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa8 heat shock protein family A (Hsp70) member 8 IMP RGD PMID:9038169 RGD:10059368 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Mt3 metallothionein 3 ISO
ISS
(MGI:MGI:4881636|PMID:20544854)
GO_REF:0000024
RGD
UniProt
PMID:20544854 GO_REF:0000024, MGI:MGI:4881636 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
positive regulation of lysosome organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grn granulin precursor ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:28073925)
(MGI:MGI:5905514|PMID:28073925)
UniProt
Ensembl
RGD
PMID:28073925 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5905514 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
regulation of lysosomal lumen pH term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC681325 hypothetical protein LOC681325 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:80,359,555...80,363,168
Ensembl chr  X:80,359,555...80,363,168
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 ISO (PMID:22012985) RGD PMID:22012985 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584
JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 ISO
IBA
(PMID:31001245)
PMID:21873635
RGD PMID:31001245, PMID:21873635 RGD:13792537 NCBI chr  X:54,390,733...54,409,466
Ensembl chr  X:54,390,733...54,409,466
JBrowse link
G Tmem165 transmembrane protein 165 ISO
ISS
(PMID:23569283)
GO_REF:0000024
RGD
UniProt
PMID:23569283 GO_REF:0000024 NCBI chr14:34,503,037...34,528,262
Ensembl chr14:34,503,038...34,528,262
JBrowse link
G Tmem175 transmembrane protein 175 ISO
ISS
(MGI:MGI:5693670|PMID:26317472)
GO_REF:0000024
RGD
UniProt
PMID:26317472 GO_REF:0000024, MGI:MGI:5693670 NCBI chr14:2,083,745...2,100,006
Ensembl chr14:2,083,712...2,100,005
JBrowse link
G Vps33a VPS33A core subunit of CORVET and HOPS complexes ISO
ISS
(PMID:28013294)
GO_REF:0000024
RGD
UniProt
PMID:28013294 GO_REF:0000024 NCBI chr12:38,459,816...38,482,903
Ensembl chr12:38,459,832...38,484,512
JBrowse link
regulation of lysosomal membrane permeability term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Laptm4b lysosomal protein transmembrane 4 beta ISO
ISS
(PMID:26280656)
GO_REF:0000024
RGD
UniProt
PMID:26280656 GO_REF:0000024 NCBI chr 7:72,924,911...72,968,099
Ensembl chr 7:72,924,799...72,968,101
JBrowse link
regulation of lysosome organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Laptm4b lysosomal protein transmembrane 4 beta ISO
ISS
(PMID:26280656)
GO_REF:0000024
RGD
UniProt
PMID:26280656 GO_REF:0000024 NCBI chr 7:72,924,911...72,968,099
Ensembl chr 7:72,924,799...72,968,101
JBrowse link
G Trex1 three prime repair exonuclease 1 ISO MGI:MGI:3052754 (MGI:MGI:5460923|PMID:23160154) RGD PMID:23160154 MGI:MGI:5460923 NCBI chr 8:117,796,127...117,797,427
Ensembl chr 8:117,796,128...117,797,427
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    cellular process 18788
      cellular component organization or biogenesis 6766
        cellular component organization 6510
          organelle organization 4073
            vacuole organization 197
              lytic vacuole organization 77
                lysosome organization 77
                  lysosomal membrane organization + 4
                  negative regulation of lysosome organization 1
                  phagolysosome assembly + 17
                  positive regulation of lysosome organization 1
                  regulation of lysosomal lumen pH + 16
                  regulation of lysosome organization + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.