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ONTOLOGY REPORT - ANNOTATIONS


Term:lysosomal lumen acidification
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Accession:GO:0007042 term browser browse the term
Definition:Any process that reduces the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.
Synonyms:exact_synonym: lysosome pH reduction


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lysosomal lumen acidification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase H+ transporting accessory protein 2 ISO
ISS
(PMID:32276428)
GO_REF:0000024
RGD
UniProt
PMID:32276428 GO_REF:0000024 NCBI chr  X:11,137,889...11,164,854
Ensembl chr  X:11,136,939...11,164,915
JBrowse link
G Ccdc115 coiled-coil domain containing 115 ISO (PMID:28296633) RGD PMID:28296633 NCBI chr 9:37,774,876...37,778,839
Ensembl chr 9:37,775,311...37,779,967
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO
IBA
ISS
(PMID:11722572)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:11722572, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
G Cln5 CLN5, intracellular trafficking protein ISO (PMID:11722572) RGD PMID:11722572 NCBI chr15:93,634,815...93,644,146 JBrowse link
G Cln6 CLN6, transmembrane ER protein ISO (PMID:11722572) RGD PMID:11722572 NCBI chr 8:67,733,215...67,748,170
Ensembl chr 8:67,733,215...67,748,172
JBrowse link
G Grn granulin precursor ISS
ISO
IEA
GO_REF:0000024
(PMID:28073925)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:28073925 GO_REF:0000024, GO_REF:0000107 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 ISO
ISS
(PMID:11722572)
PMID:8895569
RGD PMID:11722572, PMID:8895569 RGD:8553248 NCBI chr 5:140,538,260...140,558,163
Ensembl chr 5:140,538,260...140,558,162
JBrowse link
G Snapin SNAP-associated protein ISO MGI:MGI:3608768 (MGI:MGI:4879078|PMID:20920792) RGD PMID:20920792 MGI:MGI:4879078 NCBI chr 2:189,878,159...189,880,743
Ensembl chr 2:189,878,168...189,880,743
JBrowse link
G Tmem106b transmembrane protein 106B ISO MGI:MGI:5319917 (MGI:MGI:6101836|PMID:28728022) RGD PMID:28728022 MGI:MGI:6101836 NCBI chr 4:39,517,679...39,534,491
Ensembl chr 4:39,517,548...39,535,169
JBrowse link
G Tmem199 transmembrane protein 199 ISO
ISS
(PMID:28296633)
GO_REF:0000024
RGD
UniProt
PMID:28296633 GO_REF:0000024 NCBI chr10:65,775,721...65,780,293
Ensembl chr10:65,775,715...65,780,349
JBrowse link
G Tmem9 transmembrane protein 9 ISO (PMID:30374053) RGD PMID:30374053 NCBI chr13:52,854,031...52,871,300
Ensembl chr13:52,854,031...52,871,297
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      cellular component organization or biogenesis 6789
        cellular component organization 6534
          organelle organization 4101
            vacuole organization 198
              lytic vacuole organization 78
                lysosome organization 78
                  regulation of lysosomal lumen pH 17
                    lysosomal lumen acidification 11
Path 2
Term Annotations click to browse term
  biological_process 20027
    biological regulation 13773
      regulation of biological quality 4280
        homeostatic process 2077
          chemical homeostasis 1334
            ion homeostasis 887
              cation homeostasis 806
                monovalent inorganic cation homeostasis 160
                  cellular monovalent inorganic cation homeostasis 109
                    regulation of cellular pH 83
                      regulation of intracellular pH 74
                        intracellular pH reduction 40
                          vacuolar acidification 22
                            lysosomal lumen acidification 11
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.