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ONTOLOGY REPORT - ANNOTATIONS


Term:cell cycle arrest
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Accession:GO:0007050 term browser browse the term
Definition:A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
Synonyms:exact_synonym: arrest of cell cycle progression;   cessation of cell cycle;   termination of cell cycle


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cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AK1 adenylate kinase 1 JBrowse link 9 127,657,338 127,678,245 RGD:9068941
G APBB1 amyloid beta precursor protein binding family B member 1 JBrowse link 11 6,210,077 6,233,992 RGD:9068941
G APBB2 amyloid beta precursor protein binding family B member 2 JBrowse link 4 40,984,632 41,386,264 RGD:9068941
G APC APC regulator of WNT signaling pathway JBrowse link 5 113,873,993 114,009,709 RGD:9068941
G ATM ATM serine/threonine kinase JBrowse link 11 106,584,228 106,728,457 RGD:9068941
G CDKN1A cyclin dependent kinase inhibitor 1A JBrowse link 6 37,436,963 37,445,599 RGD:9068941
G CDKN1B cyclin dependent kinase inhibitor 1B JBrowse link 12 13,120,306 13,125,541 RGD:9068941
G CDKN2A cyclin dependent kinase inhibitor 2A JBrowse link 9 22,420,748 22,447,243 RGD:9068941
G CDKN2B cyclin dependent kinase inhibitor 2B JBrowse link 9 22,455,662 22,462,156 RGD:9068941
G CDKN2C cyclin dependent kinase inhibitor 2C JBrowse link 1 51,704,528 51,718,374 RGD:9068941
G CDKN2D cyclin dependent kinase inhibitor 2D JBrowse link 19 10,780,683 10,782,829 RGD:9068941
G CDKN3 cyclin dependent kinase inhibitor 3 JBrowse link 14 53,263,518 53,287,119 RGD:9068941
G COMMD5 COMM domain containing 5 JBrowse link 8 144,604,228 144,607,656 RGD:9068941
G CXCL8 C-X-C motif chemokine ligand 8 JBrowse link 4 56,285,026 56,288,308 RGD:9068941
G DDIT3 DNA damage inducible transcript 3 JBrowse link 12 31,664,766 31,668,699 RGD:9068941
G ERN1 endoplasmic reticulum to nucleus signaling 1 JBrowse link 17 63,226,949 63,317,825 RGD:9068941
G ERN2 endoplasmic reticulum to nucleus signaling 2 JBrowse link 16 23,940,716 23,963,894 RGD:9068941
G FOXO4 forkhead box O4 JBrowse link X 70,422,504 70,429,971 RGD:9068941
G GAS2L1 growth arrest specific 2 like 1 JBrowse link 22 28,169,388 28,175,278 RGD:9068941
G HRAS HRas proto-oncogene, GTPase JBrowse link 11 568,305 571,078 RGD:9068941
G IFNG interferon gamma JBrowse link 12 68,448,861 68,453,829 RGD:9068941
G IL12A interleukin 12A JBrowse link 3 165,061,505 165,068,666 RGD:9068941
G IL12B interleukin 12B JBrowse link 5 161,323,402 161,339,051 RGD:9068941
G ILK integrin linked kinase JBrowse link 11 6,418,717 6,425,788 RGD:9068941
G ING4 inhibitor of growth family member 4 JBrowse link 12 6,698,842 6,710,955 RGD:9068941
G INHBA inhibin subunit beta A JBrowse link 7 42,580,730 42,598,712 RGD:9068941
G IRF1 interferon regulatory factor 1 JBrowse link 5 134,066,250 134,075,035 RGD:9068941
G IRF6 interferon regulatory factor 6 JBrowse link 1 190,226,722 190,247,145 RGD:9068941
G JMY junction mediating and regulatory protein, p53 cofactor JBrowse link 5 36,251,080 36,567,564 RGD:9068941
G KLLN killin, p53 regulated DNA replication inhibitor JBrowse link 10 88,088,758 88,093,022 RGD:9068941
G LOC100972297 polycystin-1 JBrowse link 16 2,176,778 2,185,337 RGD:9068941
G MAP2K1 mitogen-activated protein kinase kinase 1 JBrowse link 15 63,613,988 63,714,928 RGD:9068941
G MAP3K20 mitogen-activated protein kinase kinase kinase 20 JBrowse link 2B 177,817,875 178,010,556 RGD:9068941
G MEN1 menin 1 JBrowse link 11 63,499,954 63,507,164 RGD:9068941
G MFN2 mitofusin 2 JBrowse link 1 11,945,849 11,981,077 RGD:9068941
G MLF1 myeloid leukemia factor 1 JBrowse link 3 163,654,983 163,689,688 RGD:9068941
G MSH2 mutS homolog 2 JBrowse link 2A 48,447,207 48,525,638 RGD:9068941
G MYC MYC proto-oncogene, bHLH transcription factor JBrowse link 8 127,130,877 127,136,861 RGD:9068941
G NOTCH1 notch receptor 1 JBrowse link 9 136,544,639 136,595,511 RGD:9068941
G NOTCH2 notch receptor 2 JBrowse link 1 117,537,162 117,612,840 RGD:9068941
G PKD2 polycystin 2, transient receptor potential cation channel JBrowse link 4 91,019,739 91,088,858 RGD:9068941
G PML PML nuclear body scaffold JBrowse link 15 71,658,884 71,710,883 RGD:9068941
G PPM1G protein phosphatase, Mg2+/Mn2+ dependent 1G JBrowse link 2A 27,473,480 27,502,384 RGD:9068941
G RASSF1 Ras association domain family member 1 JBrowse link 3 51,491,548 51,502,386 RGD:9068941
G RB1 RB transcriptional corepressor 1 JBrowse link 13 48,155,608 48,326,396 RGD:9068941
G RBM38 RNA binding motif protein 38 JBrowse link 20 55,010,623 55,027,746 RGD:9068941
G RNF112 ring finger protein 112 JBrowse link 17 36,860,202 36,866,805 RGD:9068941
G RPRM reprimo, TP53 dependent G2 arrest mediator homolog JBrowse link 2B 158,008,875 158,010,364 RGD:9068941
G SKIL SKI like proto-oncogene JBrowse link 3 175,562,001 175,600,181 RGD:9068941
G SMAD3 SMAD family member 3 JBrowse link 15 64,284,949 64,414,185 RGD:9068941
G SOX2 SRY-box transcription factor 2 JBrowse link 3 186,922,223 186,924,785 RGD:9068941
G STK11 serine/threonine kinase 11 JBrowse link 19 1,188,537 1,210,677 RGD:9068941
G TBRG1 transforming growth factor beta regulator 1 JBrowse link 11 123,365,969 123,379,543 RGD:9068941
G TCF7L2 transcription factor 7 like 2 JBrowse link 10 112,991,588 113,193,992 RGD:9068941
G TGFB1 transforming growth factor beta 1 JBrowse link 19 46,831,659 46,852,973 RGD:9068941
G TGFB2 transforming growth factor beta 2 JBrowse link 1 198,758,718 198,856,853 RGD:9068941
G THBS1 thrombospondin 1 JBrowse link 15 36,776,756 36,793,469 RGD:9068941
G TP53 tumor protein p53 JBrowse link 17 7,687,132 7,706,120 RGD:9068941
G TP53INP1 tumor protein p53 inducible nuclear protein 1 JBrowse link 8 93,747,162 93,767,196 RGD:9068941
G TP73 tumor protein p73 JBrowse link 1 3,476,064 3,529,206 RGD:9068941
G TSG101 tumor susceptibility 101 JBrowse link 11 18,201,381 18,248,149 RGD:9068941
G UHMK1 U2AF homology motif kinase 1 JBrowse link 1 141,708,494 141,740,278 RGD:9068941
G WDR6 WD repeat domain 6 JBrowse link 3 50,013,570 50,022,034 RGD:9068941
G WNT10B Wnt family member 10B JBrowse link 12 40,659,106 40,665,734 RGD:9068941
G ZBTB49 zinc finger and BTB domain containing 49 JBrowse link 4 4,370,748 4,401,649 RGD:9068941
G ZFHX3 zinc finger homeobox 3 JBrowse link 16 72,631,428 72,895,974 RGD:9068941
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CASP2 caspase 2 JBrowse link 7 147,773,749 147,792,958 RGD:9068941
G CDKN1A cyclin dependent kinase inhibitor 1A JBrowse link 6 37,436,963 37,445,599 RGD:9068941
G CRADD CASP2 and RIPK1 domain containing adaptor with death domain JBrowse link 12 94,619,877 94,836,970 RGD:9068941
G MDM2 MDM2 proto-oncogene JBrowse link 12 69,102,083 69,133,278 RGD:9068941
G MUC1 mucin 1, cell surface associated JBrowse link 1 134,141,969 134,146,791 RGD:9068941
G PIDD1 p53-induced death domain protein 1 JBrowse link 11 860,899 871,142 RGD:9068941
G PML PML nuclear body scaffold JBrowse link 15 71,658,884 71,710,883 RGD:9068941
G PPP2R5C protein phosphatase 2 regulatory subunit B'gamma JBrowse link 14 102,206,546 102,372,978 RGD:9068941
G RBM38 RNA binding motif protein 38 JBrowse link 20 55,010,623 55,027,746 RGD:9068941
G RPL26 ribosomal protein L26 JBrowse link 17 48,008,951 48,015,977 RGD:9068941
G SOX4 SRY-box transcription factor 4 JBrowse link 6 21,765,921 21,771,728 RGD:9068941
G TP53 tumor protein p53 JBrowse link 17 7,687,132 7,706,120 RGD:9068941
mitotic cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CDKN1A cyclin dependent kinase inhibitor 1A JBrowse link 6 37,436,963 37,445,599 RGD:9068941
G CDKN1B cyclin dependent kinase inhibitor 1B JBrowse link 12 13,120,306 13,125,541 RGD:9068941
G DDIAS DNA damage induced apoptosis suppressor JBrowse link 11 81,579,459 81,612,237 RGD:9068941
G FAP fibroblast activation protein alpha JBrowse link 2B 166,832,669 166,905,515 RGD:9068941
G GADD45A growth arrest and DNA damage inducible alpha JBrowse link 1 68,880,912 68,884,188 RGD:9068941
G GADD45GIP1 GADD45G interacting protein 1 JBrowse link 19 13,258,995 13,262,059 RGD:9068941
G MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 JBrowse link 7 83,759,307 84,511,987 RGD:9068941
G MCPH1 microcephalin 1 JBrowse link 8 6,409,072 6,651,846 RGD:9068941
G MFN2 mitofusin 2 JBrowse link 1 11,945,849 11,981,077 RGD:9068941
G NKX3-1 NK3 homeobox 1 JBrowse link 8 19,860,748 19,864,968 RGD:9068941
G PNPT1 polyribonucleotide nucleotidyltransferase 1 JBrowse link 2A 56,931,110 56,986,408 RGD:9068941
G RGCC regulator of cell cycle JBrowse link 13 41,228,643 41,241,909 RGD:9068941
G TP53 tumor protein p53 JBrowse link 17 7,687,132 7,706,120 RGD:9068941
negative regulation of cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CALR calreticulin JBrowse link 19 13,242,900 13,249,416 RGD:9068941
G CAST calpastatin JBrowse link 5 97,526,828 97,639,645 RGD:9068941
G CCND1 cyclin D1 JBrowse link 11 68,029,134 68,041,553 RGD:9068941
G CDK4 cyclin dependent kinase 4 JBrowse link 12 31,434,594 31,438,876 RGD:9068941
G CDK9 cyclin dependent kinase 9 JBrowse link 9 127,580,862 127,584,936 RGD:9068941
G CHEK2 checkpoint kinase 2 JBrowse link 22 27,455,226 27,512,555 RGD:9068941
G FGF10 fibroblast growth factor 10 JBrowse link 5 71,028,324 71,111,713 RGD:9068941
G FOXE3 forkhead box E3 RGD:9068941
G FZD9 frizzled class receptor 9 JBrowse link 7 80,588,167 80,590,337 RGD:9068941
G HMGN5 high mobility group nucleosome binding domain 5 JBrowse link X 80,285,151 80,373,078 RGD:9068941
G HSP90AB1 heat shock protein 90 alpha family class B member 1 JBrowse link 6 45,126,060 45,132,972 RGD:9068941
G LOC100967334 G-protein coupled estrogen receptor 1 JBrowse link 7 1,454,768 1,461,376 RGD:9068941
G LOC100986203 histone-lysine N-methyltransferase SETMAR JBrowse link 3 4,357,779 4,371,810 RGD:9068941
G MDM2 MDM2 proto-oncogene JBrowse link 12 69,102,083 69,133,278 RGD:9068941
G MIF macrophage migration inhibitory factor JBrowse link 22 22,729,245 22,732,009 RGD:9068941
G MLXIPL MLX interacting protein like JBrowse link 7 80,745,765 80,776,156 RGD:9068941
G NUPR2 nuclear protein 2, transcriptional regulator JBrowse link 7 57,149,240 57,150,946 RGD:9068941
G RASSF1 Ras association domain family member 1 JBrowse link 3 51,491,548 51,502,386 RGD:9068941
G RPL23 ribosomal protein L23 JBrowse link 17 18,690,682 18,694,434 RGD:9068941
G TFAP4 transcription factor AP-4 JBrowse link 16 4,348,066 4,394,809 RGD:9068941
G ZNF268 zinc finger protein 268 JBrowse link 12 135,265,029 135,290,457 RGD:9068941
positive regulation of cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BRCA1 BRCA1 DNA repair associated JBrowse link 17 14,429,601 14,506,815 RGD:9068941
G CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 JBrowse link 17 24,575,561 24,579,226 RGD:9068941
G CDKN2A cyclin dependent kinase inhibitor 2A JBrowse link 9 22,420,748 22,447,243 RGD:9068941
G CRLF3 cytokine receptor like factor 3 JBrowse link 17 25,523,472 25,545,460 RGD:9068941
G DAB2IP DAB2 interacting protein JBrowse link 9 121,206,211 121,254,336 RGD:9068941
G FAP fibroblast activation protein alpha JBrowse link 2B 166,832,669 166,905,515 RGD:9068941
G FOXO4 forkhead box O4 JBrowse link X 70,422,504 70,429,971 RGD:9068941
G GATA6 GATA binding protein 6 JBrowse link 18 19,046,132 19,078,398 RGD:9068941
G HMGA2 high mobility group AT-hook 2 RGD:9068941
G ID2 inhibitor of DNA binding 2 JBrowse link 2A 8,847,776 8,850,720 RGD:9068941
G INSM1 INSM transcriptional repressor 1 JBrowse link 20 20,277,885 20,281,143 RGD:9068941
G MED25 mediator complex subunit 25 JBrowse link 19 55,747,445 55,765,978 RGD:9068941
G MYBBP1A MYB binding protein 1a JBrowse link 17 4,586,431 4,603,097 RGD:9068941
G MYOG myogenin JBrowse link 1 182,979,700 182,982,607 RGD:9068941
G PKD2 polycystin 2, transient receptor potential cation channel JBrowse link 4 91,019,739 91,088,858 RGD:9068941
G POU4F1 POU class 4 homeobox 1 JBrowse link 13 78,863,468 78,863,992 RGD:9068941
G PPP2R5B protein phosphatase 2 regulatory subunit B'beta JBrowse link 11 63,621,745 63,631,779 RGD:9068941
G PRKACA protein kinase cAMP-activated catalytic subunit alpha JBrowse link 19 14,385,183 14,406,205 RGD:9068941
G RGCC regulator of cell cycle JBrowse link 13 41,228,643 41,241,909 RGD:9068941
G RIPOR2 RHO family interacting cell polarization regulator 2 JBrowse link 6 24,973,412 25,099,034 RGD:9068941
G RNF112 ring finger protein 112 JBrowse link 17 36,860,202 36,866,805 RGD:9068941
G RPL23 ribosomal protein L23 JBrowse link 17 18,690,682 18,694,434 RGD:9068941
G RRP8 ribosomal RNA processing 8 JBrowse link 11 6,314,285 6,418,557 RGD:9068941
G TGFB1 transforming growth factor beta 1 JBrowse link 19 46,831,659 46,852,973 RGD:9068941
G TP53 tumor protein p53 JBrowse link 17 7,687,132 7,706,120 RGD:9068941
G TP73 tumor protein p73 JBrowse link 1 3,476,064 3,529,206 RGD:9068941
G UHRF2 ubiquitin like with PHD and ring finger domains 2 JBrowse link 9 6,409,081 6,502,484 RGD:9068941
G ZBTB17 zinc finger and BTB domain containing 17 JBrowse link 1 16,074,005 16,106,709 RGD:9068941
regulation of cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BIN1 bridging integrator 1 JBrowse link 2B 127,716,543 127,775,378 RGD:9068941
G FOXM1 forkhead box M1 JBrowse link 12 2,910,028 2,930,503 RGD:9068941
G MASTL microtubule associated serine/threonine kinase like JBrowse link 10 27,626,892 27,658,180 RGD:9068941
G NEUROD1 neuronal differentiation 1 JBrowse link 2B 186,749,155 186,753,541 RGD:9068941
G SDE2 SDE2 telomere maintenance homolog JBrowse link 1 206,441,517 206,457,679 RGD:9068941
G SLC25A33 solute carrier family 25 member 33 JBrowse link 1 9,493,787 9,574,549 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12491
    cellular process 11602
      cell cycle process 997
        cell cycle arrest 126
          G1 cell cycle arrest in response to nitrogen starvation + 0
          cell cycle arrest of committed forebrain neuronal progenitor cell 0
          mitotic cell cycle arrest + 13
          negative regulation of cell cycle arrest 21
          positive regulation of cell cycle arrest + 39
          regulation of cell cycle arrest + 64
Path 2
Term Annotations click to browse term
  biological_process 12491
    biological regulation 9102
      regulation of biological process 8628
        negative regulation of biological process 4825
          negative regulation of cellular process 4390
            negative regulation of cell cycle 403
              cell cycle arrest 126
                G1 cell cycle arrest in response to nitrogen starvation + 0
                cell cycle arrest of committed forebrain neuronal progenitor cell 0
                mitotic cell cycle arrest + 13
                negative regulation of cell cycle arrest 21
                positive regulation of cell cycle arrest + 39
                regulation of cell cycle arrest + 64
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.