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ONTOLOGY REPORT - ANNOTATIONS


Term:mitotic spindle organization
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Accession:GO:0007052 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
Comment:In fission yeast most mitotic spindle organization occurs in the nucleus; see https://github.com/geneontology/go-ontology/issues/15341.
Synonyms:exact_synonym: mitotic spindle organisation;   spindle organization and biogenesis during mitosis
 narrow_synonym: mitotic spindle organisation in nucleus;   mitotic spindle organization and biogenesis in cell nucleus;   mitotic spindle organization and biogenesis in nucleus;   mitotic spindle organization in nucleus;   spindle organization and biogenesis in nucleus during mitosis
 related_synonym: mitotic spindle organization and biogenesis;   mitotic spindle stabilization
 alt_id: GO:0000071;   GO:0030472;   GO:0043148


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mitotic spindle organization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aurka aurora kinase A JBrowse link 3 170,364,177 170,380,278 RGD:1600115
RGD:13792537
RGD:1624291
G Aurkb aurora kinase B JBrowse link 10 55,625,860 55,632,399 RGD:13792537
G Aurkc aurora kinase C JBrowse link 1 69,958,452 69,964,546 RGD:13792537
G Bccip BRCA2 and CDKN1A interacting protein JBrowse link 1 205,777,474 205,789,887 RGD:1624291
RGD:13792537
G Ccnb1 cyclin B1 JBrowse link 2 30,782,133 30,791,106 RGD:1624291
G Cenpe centromere protein E JBrowse link 2 240,395,974 240,454,785 RGD:1624291
G Cenph centromere protein H JBrowse link 2 30,766,637 30,780,123 RGD:13792537
G Cep126 centrosomal protein 126 JBrowse link 8 6,237,838 6,305,127 RGD:1624291
G Ckap5 cytoskeleton associated protein 5 JBrowse link 3 80,424,320 80,526,583 RGD:13792537
G Clasp1 cytoplasmic linker associated protein 1 JBrowse link 13 34,365,038 34,584,651 RGD:1624291
G Clasp2 cytoplasmic linker associated protein 2 JBrowse link 8 122,003,719 122,185,495 RGD:1624291
RGD:1600115
G Dctn2 dynactin subunit 2 JBrowse link 7 70,555,953 70,571,433 RGD:1331348
RGD:1624291
RGD:1600115
RGD:13792537
G Dctn6 dynactin subunit 6 JBrowse link 16 61,795,544 61,814,734 RGD:1624291
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 JBrowse link 8 122,743,274 122,776,801 RGD:70723
G Efhc1 EF-hand domain containing 1 JBrowse link 9 27,068,505 27,107,713 RGD:1624291
RGD:13792537
G Eml1 EMAP like 1 JBrowse link 6 132,367,342 132,450,488 RGD:1624291
RGD:1600115
G Gpsm2 G-protein signaling modulator 2 JBrowse link 2 211,480,120 211,528,096 RGD:1624291
G Ints13 integrator complex subunit 13 JBrowse link 4 180,854,988 180,887,095 RGD:1624291
G Kif2a kinesin family member 2A JBrowse link 2 38,145,507 38,208,765 RGD:1624291
RGD:1600115
G Kif4a kinesin family member 4A JBrowse link X 70,461,700 70,561,084 RGD:13792537
G Map4 microtubule-associated protein 4 JBrowse link 8 118,013,584 118,159,934 RGD:1624291
G Mecp2 methyl CpG binding protein 2 JBrowse link X 156,650,389 156,713,813 RGD:1600115
RGD:1624291
G Ndc80 NDC80 kinetochore complex component JBrowse link 9 119,837,857 119,871,435 RGD:1624291
G NEWGENE_1306714 WD repeat domain 62-like 1 JBrowse link 1 88,694,824 88,734,305 RGD:13792537
G Nuf2 NUF2 component of NDC80 kinetochore complex JBrowse link 13 87,818,456 87,847,223 RGD:13792537
G Pcnt pericentrin JBrowse link 20 12,943,523 13,038,615 RGD:1624291
G Plk2 polo-like kinase 2 JBrowse link 2 41,911,143 41,916,901 RGD:1624291
RGD:1600115
G Poc1a POC1 centriolar protein A JBrowse link 8 114,982,764 115,050,844 RGD:1624291
G Ptpa protein phosphatase 2 phosphatase activator JBrowse link 3 8,982,122 9,012,585 RGD:13792537
G Ralbp1 ralA binding protein 1 JBrowse link 9 113,579,107 113,598,477 RGD:2324919
G Rcc1 regulator of chromosome condensation 1 JBrowse link 5 150,508,840 150,531,062 RGD:1624291
G Sbds SBDS, ribosome maturation factor JBrowse link 12 29,921,443 29,930,602 RGD:1624291
G Spc25 SPC25 component of NDC80 kinetochore complex JBrowse link 3 55,438,534 55,451,961 RGD:1624291
RGD:1600115
G Stil STIL, centriolar assembly protein JBrowse link 5 133,819,302 133,851,362 RGD:1624291
RGD:13792537
G Stmn1 stathmin 1 JBrowse link 5 152,680,412 152,686,807 RGD:1624291
G Tacc1 transforming, acidic coiled-coil containing protein 1 JBrowse link 16 71,596,970 71,681,126 RGD:1600115
G Tacc2 transforming, acidic coiled-coil containing protein 2 JBrowse link 1 201,140,264 201,329,612 RGD:1600115
G Tacc3 transforming, acidic coiled-coil containing protein 3 JBrowse link 14 82,336,283 82,350,069 RGD:1600115
G Tbce tubulin folding cofactor E JBrowse link 17 53,983,126 54,029,028 RGD:1624291
RGD:1600115
G Tubg1 tubulin, gamma 1 JBrowse link 10 89,030,865 89,037,455 RGD:13792537
G Tubg2 tubulin, gamma 2 JBrowse link 10 89,069,223 89,075,589 RGD:13792537
G Wdr62 WD repeat domain 62 JBrowse link 1 90,995,545 91,034,592 RGD:1624291
RGD:13792537
mitotic spindle assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aaas aladin WD repeat nucleoporin JBrowse link 7 143,937,198 143,956,668 RGD:1624291
G Abraxas1 abraxas 1, BRCA1 A complex subunit JBrowse link 14 10,424,674 10,439,010 RGD:13792537
G Abraxas2 abraxas 2, BRISC complex subunit JBrowse link 1 204,861,768 204,887,344 RGD:1624291
RGD:13792537
G Arhgef10 Rho guanine nucleotide exchange factor 10 JBrowse link 16 79,725,629 79,817,065 RGD:1624291
RGD:13792537
G Bccip BRCA2 and CDKN1A interacting protein JBrowse link 1 205,777,474 205,789,887 RGD:1624291
RGD:13792537
G Cdc20 cell division cycle 20 JBrowse link 5 137,260,728 137,264,931 RGD:1624291
G Cep192 centrosomal protein 192 JBrowse link 18 63,572,084 63,656,302 RGD:1624291
G Chek2 checkpoint kinase 2 JBrowse link 12 51,845,574 51,878,098 RGD:1624291
G Flna filamin A JBrowse link X 156,460,785 156,487,245 RGD:1624291
G Golga2 golgin A2 JBrowse link 3 11,317,328 11,337,569 RGD:10400867
RGD:1600115
RGD:1624291
G Khdc3 KH domain containing 3, subcortical maternal complex member JBrowse link 8 79,781,941 79,783,845 RGD:1624291
G Kif11 kinesin family member 11 JBrowse link 1 256,035,866 256,088,299 RGD:1624291
RGD:13792537
G Kif2a kinesin family member 2A JBrowse link 2 38,145,507 38,208,765 RGD:1600115
RGD:1624291
G Kif3b kinesin family member 3B JBrowse link 3 148,772,937 148,813,342 RGD:1624291
G Kifc1 kinesin family member C1 JBrowse link 20 5,509,059 5,526,175 RGD:1624291
RGD:13792537
RGD:1600115
G Kpnb1 karyopherin subunit beta 1 JBrowse link 10 85,096,517 85,124,641 RGD:1600115
RGD:1624291
G Map9 microtubule-associated protein 9 JBrowse link 2 181,331,426 181,367,245 RGD:1624291
RGD:13792537
G Misp mitotic spindle positioning JBrowse link 7 12,691,834 12,707,927 RGD:1624291
G Msto1 misato mitochondrial distribution and morphology regulator 1 JBrowse link 2 188,212,211 188,216,482 RGD:13792537
G Mybl2 MYB proto-oncogene like 2 JBrowse link 3 159,421,638 159,450,087 RGD:1624291
G Mzt1 mitotic spindle organizing protein 1 JBrowse link 15 83,429,437 83,442,118 RGD:13792537
G Nek2 NIMA-related kinase 2 JBrowse link 13 110,511,546 110,524,750 RGD:1624291
G Ofd1 OFD1, centriole and centriolar satellite protein JBrowse link X 29,562,165 29,602,934 RGD:1624291
G Pibf1 progesterone immunomodulatory binding factor 1 JBrowse link 15 83,494,110 83,663,202 RGD:1624291
G Rab11a RAB11a, member RAS oncogene family JBrowse link 8 70,192,975 70,215,719 RGD:1624291
G Rhoa ras homolog family member A JBrowse link 8 117,082,440 117,116,244 RGD:1624291
G Spice1 spindle and centriole associated protein 1 JBrowse link 11 61,250,649 61,294,116 RGD:1600115
RGD:13792537
RGD:1624291
G Tpx2 TPX2, microtubule nucleation factor JBrowse link 3 148,327,965 148,370,187 RGD:1624291
G Wrap73 WD repeat containing, antisense to TP73 JBrowse link 5 171,441,471 171,455,795 RGD:1624291
RGD:1600115
G Zfp207 zinc finger protein 207 JBrowse link 10 67,762,970 67,784,854 RGD:1624291
RGD:13792537
mitotic spindle disassembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Spast spastin JBrowse link 6 22,230,067 22,282,166 RGD:1624291
RGD:1600115
G Vcp valosin-containing protein JBrowse link 5 58,426,548 58,445,953 RGD:13792537
mitotic spindle midzone assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aurkb aurora kinase B JBrowse link 10 55,625,860 55,632,399 RGD:1624291
RGD:1600115
G Kif23 kinesin family member 23 JBrowse link 8 66,866,043 66,893,241 RGD:1624291
RGD:13792537
G Kif4a kinesin family member 4A JBrowse link X 70,461,700 70,561,084 RGD:1624291
G Map10 microtubule-associated protein 10 JBrowse link 19 58,505,811 58,508,603 RGD:1624291
RGD:13792537
RGD:1600115
G Racgap1 Rac GTPase-activating protein 1 JBrowse link 7 141,277,303 141,308,849 RGD:1624291
positive regulation of mitotic spindle elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Numa1 nuclear mitotic apparatus protein 1 JBrowse link 1 167,044,544 167,091,453 RGD:1624291
regulation of mitotic spindle assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccsap centriole, cilia and spindle-associated protein JBrowse link 19 56,615,326 56,634,031 RGD:1624291
G Cep97 centrosomal protein 97 JBrowse link 11 47,146,409 47,174,460 RGD:1624291
G Chmp1a charged multivesicular body protein 1A JBrowse link 19 56,001,724 56,010,004 RGD:1624291
G Chmp1b charged multivesicular body protein 1B JBrowse link 18 62,923,620 62,926,150 RGD:1624291
G Chmp2a charged multivesicular body protein 2A JBrowse link 1 65,540,808 65,543,708 RGD:1624291
G Chmp2b charged multivesicular body protein 2B JBrowse link 11 2,666,405 2,692,213 RGD:1624291
G Chmp3 charged multivesicular body protein 3 JBrowse link 4 99,449,213 99,496,156 RGD:1624291
G Chmp4b charged multivesicular body protein 4B JBrowse link 3 150,188,275 150,227,453 RGD:1624291
G Chmp4c charged multivesicular body protein 4C JBrowse link 2 93,574,554 93,641,497 RGD:1600115
RGD:1624291
G Chmp5 charged multivesicular body protein 5 JBrowse link 5 57,267,312 57,284,455 RGD:1624291
G Drg1 developmentally regulated GTP binding protein 1 JBrowse link 14 83,460,540 83,476,568 RGD:1624291
G Hnrnpu heterogeneous nuclear ribonucleoprotein U JBrowse link 13 96,222,093 96,238,845 RGD:1600115
RGD:13792537
RGD:1624291
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:1624291
RGD:13792537
RGD:1600115
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:1624291
RGD:13792537
RGD:1600115
G LOC108348108 heat shock 70 kDa protein 1A JBrowse link 20 2,699,707 2,701,856 RGD:1600115
RGD:13792537
G Pdcd6ip programmed cell death 6 interacting protein JBrowse link 8 121,916,233 121,973,145 RGD:1624291
G Plk1 polo-like kinase 1 JBrowse link 1 192,115,990 192,125,969 RGD:1624291
RGD:1600115
G Rcc1 regulator of chromosome condensation 1 JBrowse link 5 150,508,840 150,531,062 RGD:13792537
G Ripor2 RHO family interacting cell polarization regulator 2 JBrowse link 17 42,324,594 42,549,907 RGD:1624291
G Smc1a structural maintenance of chromosomes 1A JBrowse link X 21,710,976 21,755,708 RGD:1600115
RGD:1624291
G Smc3 structural maintenance of chromosomes 3 JBrowse link 1 274,310,120 274,352,856 RGD:1600115
RGD:1624291
G Stag1 stromal antigen 1 JBrowse link 8 108,958,099 109,342,738 RGD:1624291
G Stag2 stromal antigen 2 JBrowse link X 128,493,603 128,624,418 RGD:1624291
G Tpr translocated promoter region, nuclear basket protein JBrowse link 13 67,611,685 67,672,833 RGD:1624291
RGD:13792537
RGD:1600115
G Vps4b vacuolar protein sorting 4 homolog B JBrowse link 13 26,825,261 26,850,460 RGD:1624291
regulation of mitotic spindle organization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ankrd53 ankyrin repeat domain 53 JBrowse link 4 115,439,325 115,447,995 RGD:1624291
G Bora bora, aurora kinase A activator JBrowse link 15 83,442,217 83,463,737 RGD:1624291
RGD:13792537
RGD:1600115
G Cltc clathrin heavy chain JBrowse link 10 74,014,560 74,070,578 RGD:1624291
G Dctn1 dynactin subunit 1 JBrowse link 4 114,876,770 114,896,567 RGD:1624291
RGD:1600115
G Dync1h1 dynein cytoplasmic 1 heavy chain 1 JBrowse link 6 134,958,854 135,085,769 RGD:1600115
RGD:1624291
G Fsd1 fibronectin type III and SPRY domain containing 1 JBrowse link 9 11,076,670 11,080,190 RGD:1624291
G Fsd1 fibronectin type 3 and SPRY domain-containing protein RGD:1600115
G Gnai1 G protein subunit alpha i1 JBrowse link 4 13,405,136 13,486,866 RGD:1624291
RGD:1600115
G Gpsm2 G-protein signaling modulator 2 JBrowse link 2 211,480,120 211,528,096 RGD:1624291
G Map9 microtubule-associated protein 9 JBrowse link 2 181,331,426 181,367,245 RGD:1624291
G Numa1 nuclear mitotic apparatus protein 1 JBrowse link 1 167,044,544 167,091,453 RGD:1624291
G Nup62 nucleoporin 62 JBrowse link 1 100,811,140 100,827,119 RGD:1624291
G Parp3 poly (ADP-ribose) polymerase family, member 3 JBrowse link 8 115,173,440 115,179,543 RGD:1624291
G Pkd1 polycystin 1, transient receptor potential channel interacting JBrowse link 10 13,914,057 13,962,008 RGD:1624291
G Psrc1 proline and serine rich coiled-coil 1 JBrowse link 2 211,176,437 211,181,078 RGD:1624291
RGD:1600115
G Rae1 ribonucleic acid export 1 JBrowse link 3 171,012,984 171,030,392 RGD:1624291
RGD:1600115
G Tacc3 transforming, acidic coiled-coil containing protein 3 JBrowse link 14 82,336,283 82,350,069 RGD:1624291
G Tpx2 TPX2, microtubule nucleation factor JBrowse link 3 148,327,965 148,370,187 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19332
    cellular process 17237
      cell cycle process 1187
        spindle organization 181
          mitotic spindle organization 113
            establishment of mitotic spindle asymmetry 0
            mitotic spindle assembly + 60
            mitotic spindle disassembly + 2
            mitotic spindle elongation + 6
            mitotic spindle elongation (spindle phase three) + 0
            mitotic spindle formation (spindle phase one) + 0
            positive regulation of mitotic spindle organization + 1
            regulation of mitotic spindle organization + 43
Path 2
Term Annotations click to browse term
  biological_process 19332
    cellular process 17237
      cellular component organization 6221
        organelle organization 3831
          cytoskeleton organization 1398
            microtubule cytoskeleton organization 607
              spindle organization 181
                mitotic spindle organization 113
                  establishment of mitotic spindle asymmetry 0
                  mitotic spindle assembly + 60
                  mitotic spindle disassembly + 2
                  mitotic spindle elongation + 6
                  mitotic spindle elongation (spindle phase three) + 0
                  mitotic spindle formation (spindle phase one) + 0
                  positive regulation of mitotic spindle organization + 1
                  regulation of mitotic spindle organization + 43
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.