ONTOLOGY REPORT - ANNOTATIONS


Term:centrosome cycle
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Accession:GO:0007098 term browser browse the term
Definition:The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle.
Synonyms:exact_synonym: centrosome organisation;   centrosome organization
 related_synonym: centrosome organization and biogenesis
 alt_id: GO:0051297
 xref: MIPS_funcat:10.03.05.01


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centrosome cycle term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arl2 ADP-ribosylation factor like GTPase 2 JBrowse link 1 221,504,150 221,516,191 RGD:1624291
RGD:1600115
G Aurka aurora kinase A JBrowse link 3 170,364,177 170,380,278 RGD:1624291
G Bbs4 Bardet-Biedl syndrome 4 JBrowse link 8 64,115,005 64,154,432 RGD:1624291
RGD:1600115
G Bnip2 BCL2 interacting protein 2 JBrowse link 8 76,400,333 76,426,307 RGD:1624291
RGD:1600115
G Brca1 BRCA1, DNA repair associated JBrowse link 10 89,394,821 89,455,093 RGD:1624291
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 JBrowse link 5 86,387,238 86,554,108 RGD:1624291
RGD:1600115
G Cep120 centrosomal protein 120 JBrowse link 18 48,658,495 48,720,570 RGD:1624291
RGD:1600115
G Cep68 centrosomal protein 68 JBrowse link 14 104,501,759 104,523,330 RGD:1624291
G Chd3 chromodomain helicase DNA binding protein 3 JBrowse link 10 55,943,467 55,970,417 RGD:1624291
RGD:1600115
G Ckap5 cytoskeleton associated protein 5 JBrowse link 3 80,424,320 80,526,583 RGD:1624291
G Crocc ciliary rootlet coiled-coil, rootletin JBrowse link 5 159,540,453 159,583,194 RGD:1624291
RGD:1600115
G Fes FES proto-oncogene, tyrosine kinase JBrowse link 1 142,174,648 142,183,884 RGD:1624291
RGD:1600115
G Gadd45a growth arrest and DNA-damage-inducible, alpha JBrowse link 4 97,782,512 97,784,814 RGD:1624291
RGD:1600115
G Golga2 golgin A2 JBrowse link 3 11,317,328 11,337,569 RGD:1600115
RGD:1624291
G Haus1 HAUS augmin-like complex, subunit 1 JBrowse link 18 74,140,759 74,151,965 RGD:1624291
RGD:13792537
RGD:1600115
G Haus3 HAUS augmin-like complex, subunit 3 JBrowse link 14 81,837,772 81,857,458 RGD:1624291
RGD:13792537
G Haus4 HAUS augmin-like complex, subunit 4 JBrowse link 15 33,182,139 33,193,880 RGD:1624291
RGD:13792537
G Haus5 HAUS augmin-like complex, subunit 5 JBrowse link 1 89,113,045 89,124,971 RGD:1624291
RGD:13792537
G Haus7 HAUS augmin-like complex, subunit 7 JBrowse link X 157,347,222 157,372,796 RGD:1624291
RGD:13792537
G Haus8 HAUS augmin-like complex, subunit 8 JBrowse link 16 19,654,785 19,669,221 RGD:1624291
RGD:13792537
RGD:1600115
G Hepacam2 HEPACAM family member 2 JBrowse link 4 28,402,862 28,437,722 RGD:1624291
RGD:13792537
G LOC108348136 HAUS augmin-like complex subunit 1 JBrowse link 18 74,185,281 74,198,416 RGD:1600115
RGD:13792537
G LOC691918 similar to Centrosomal protein of 27 kDa (Cep27 protein) JBrowse link 3 112,371,709 112,377,939 RGD:1624291
RGD:1600115
G Npm1 nucleophosmin 1 JBrowse link 10 18,080,949 18,091,062 RGD:1624291
RGD:1600115
G Nup62 nucleoporin 62 JBrowse link 1 100,811,140 100,827,119 RGD:1624291
G Pard6a par-6 family cell polarity regulator alpha JBrowse link 19 37,668,133 37,670,450 RGD:1600115
RGD:13792537
RGD:1624291
G Pard6b par-6 family cell polarity regulator beta JBrowse link 3 164,822,111 164,843,395 RGD:13792537
G Pard6g par-6 family cell polarity regulator gamma JBrowse link 18 76,559,877 76,627,843 RGD:13792537
G Pclaf PCNA clamp associated factor JBrowse link 8 71,514,281 71,526,182 RGD:1624291
RGD:1600115
G Pcm1 pericentriolar material 1 JBrowse link 16 54,040,721 54,137,675 RGD:1624291
RGD:13792537
G Plk1 polo-like kinase 1 JBrowse link 1 192,115,990 192,125,969 RGD:1600115
RGD:1624291
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A JBrowse link 7 51,404,971 51,515,382 RGD:1600115
RGD:1624291
G Sdccag8 serologically defined colon cancer antigen 8 JBrowse link 13 94,888,046 95,100,833 RGD:1600115
G Slc16a1 solute carrier family 16 member 1 JBrowse link 2 207,108,552 207,129,352 RGD:1624291
RGD:1600115
G Ssx2ip SSX family member 2 interacting protein JBrowse link 2 252,263,323 252,296,049 RGD:1624291
RGD:1600115
G Uvrag UV radiation resistance associated JBrowse link 1 163,844,804 164,101,568 RGD:1624291
RGD:1600115
G Uxt ubiquitously-expressed, prefoldin-like chaperone JBrowse link X 1,275,402 1,287,781 RGD:1624291
RGD:13792537
RGD:1600115
G Xrcc2 X-ray repair cross complementing 2 JBrowse link 4 5,842,013 5,860,516 RGD:1624291
RGD:1600115
centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C2cd3 C2 calcium-dependent domain containing 3 JBrowse link 1 165,382,279 165,480,088 RGD:1624291
RGD:1600115
G Cenpj centromere protein J JBrowse link 15 36,745,672 36,809,228 RGD:1624291
RGD:1600115
centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccp110 centriolar coiled-coil protein 110 JBrowse link 1 188,417,012 188,444,991 RGD:1624291
RGD:1600115
G Cdk2 cyclin dependent kinase 2 JBrowse link 7 3,124,953 3,132,533 RGD:1600115
RGD:1624291
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 JBrowse link 5 86,387,238 86,554,108 RGD:1600115
RGD:1624291
G Cenpj centromere protein J JBrowse link 15 36,745,672 36,809,228 RGD:1624291
G Cep135 centrosomal protein 135 JBrowse link 14 34,052,168 34,115,763 RGD:1624291
RGD:1600115
G Cep152 centrosomal protein 152 JBrowse link 3 117,822,799 117,894,856 RGD:1624291
G Cep63 centrosomal protein 63 JBrowse link 8 111,063,988 111,116,014 RGD:1600115
RGD:13792537
RGD:1624291
G Cep72 centrosomal protein 72 JBrowse link 1 31,834,977 31,864,938 RGD:1624291
RGD:1600115
G Cetn1 centrin 1 JBrowse link 18 785,972 786,674 RGD:13792537
G Cetn2 centrin 2 JBrowse link X 152,927,852 152,933,095 RGD:1624291
RGD:13792537
G Cntrob centrobin, centriole duplication and spindle assembly protein JBrowse link 10 55,901,929 55,927,121 RGD:1624291
RGD:13792537
G Deup1 deuterosome assembly protein 1 JBrowse link 8 14,094,742 14,157,232 RGD:13792537
G Ofd1 OFD1, centriole and centriolar satellite protein JBrowse link X 29,562,165 29,602,934 RGD:1624291
G Plk4 polo-like kinase 4 JBrowse link 2 127,686,911 127,705,518 RGD:1600115
RGD:13792537
RGD:1624291
G RGD1304728 similar to 4933427D14Rik protein JBrowse link 10 58,726,721 58,776,718 RGD:1600115
G Sass6 SAS-6 centriolar assembly protein JBrowse link 2 219,626,851 219,660,975 RGD:1624291
RGD:1600115
G Wdr62 WD repeat domain 62 JBrowse link 1 90,995,545 91,034,592 RGD:1624291
centriole-centriole cohesion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cep135 centrosomal protein 135 JBrowse link 14 34,052,168 34,115,763 RGD:1624291
RGD:1600115
G Cep250 centrosomal protein 250 JBrowse link 3 151,508,366 151,544,631 RGD:1624291
RGD:1600115
G Cep68 centrosomal protein 68 JBrowse link 14 104,501,759 104,523,330 RGD:1624291
RGD:13792537
G Cntln centlein JBrowse link 5 103,251,986 103,367,088 RGD:1624291
RGD:13792537
G Crocc ciliary rootlet coiled-coil, rootletin JBrowse link 5 159,540,453 159,583,194 RGD:1624291
RGD:1600115
G Dctn1 dynactin subunit 1 JBrowse link 4 114,876,770 114,896,567 RGD:1624291
RGD:1600115
G Kif3a kinesin family member 3a JBrowse link 10 38,918,705 38,953,958 RGD:1624291
RGD:1600115
G Nin ninein JBrowse link 6 92,423,412 92,527,776 RGD:1624291
G Odf2 outer dense fiber of sperm tails 2 JBrowse link 3 8,449,733 8,495,764 RGD:1624291
RGD:1600115
G Sgo1 shugoshin 1 JBrowse link 9 4,420,158 4,435,939 RGD:1624291
centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arhgef10 Rho guanine nucleotide exchange factor 10 JBrowse link 16 79,725,629 79,817,065 RGD:1624291
RGD:1600115
G Brca2 BRCA2, DNA repair associated JBrowse link 12 503,660 544,754 RGD:1600115
RGD:1624291
G Brsk1 BR serine/threonine kinase 1 JBrowse link 1 72,701,281 72,727,061 RGD:1624291
RGD:1600115
G Ccp110 centriolar coiled-coil protein 110 JBrowse link 1 188,417,012 188,444,991 RGD:1624291
G Cenpj centromere protein J JBrowse link 15 36,745,672 36,809,228 RGD:1624291
G Cep152 centrosomal protein 152 JBrowse link 3 117,822,799 117,894,856 RGD:1624291
G Cep192 centrosomal protein 192 JBrowse link 18 63,572,084 63,656,302 RGD:1600115
G Cep63 centrosomal protein 63 JBrowse link 8 111,063,988 111,116,014 RGD:1624291
G Ckap5 cytoskeleton associated protein 5 JBrowse link 3 80,424,320 80,526,583 RGD:13792537
G Nde1 nudE neurodevelopment protein 1 JBrowse link 10 860,513 904,624 RGD:1624291
RGD:1600115
G Rock2 Rho-associated coiled-coil containing protein kinase 2 JBrowse link 6 42,180,864 42,289,910 RGD:1600115
RGD:1624291
G Sac3d1 SAC3 domain containing 1 JBrowse link 1 221,484,210 221,486,669 RGD:1624291
G Sass6 SAS-6 centriolar assembly protein JBrowse link 2 219,626,851 219,660,975 RGD:1624291
G Stil STIL, centriolar assembly protein JBrowse link 5 133,819,302 133,851,362 RGD:1624291
RGD:13792537
G Usp33 ubiquitin specific peptidase 33 JBrowse link 2 257,567,179 257,602,817 RGD:1624291
RGD:1600115
centrosome separation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cntrob centrobin, centriole duplication and spindle assembly protein JBrowse link 10 55,901,929 55,927,121 RGD:1624291
RGD:13792537
G Nek2 NIMA-related kinase 2 JBrowse link 13 110,511,546 110,524,750 RGD:1624291
G Nek2l1 NIMA (never in mitosis gene a)-related kinase 2-like 1 JBrowse link 8 15,940,934 15,942,589 RGD:1600115
mitotic centrosome separation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aurka aurora kinase A JBrowse link 3 170,364,177 170,380,278 RGD:1600115
RGD:1624291
G Kif11 kinesin family member 11 JBrowse link 1 256,035,866 256,088,299 RGD:1624291
RGD:1600115
G Nde1 nudE neurodevelopment protein 1 JBrowse link 10 860,513 904,624 RGD:13792537
G Ndel1 nudE neurodevelopment protein 1-like 1 JBrowse link 10 55,398,919 55,456,654 RGD:1624291
RGD:13792537
G Nup62 nucleoporin 62 JBrowse link 1 100,811,140 100,827,119 RGD:1624291
RGD:1600115
negative regulation of centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chmp2a charged multivesicular body protein 2A JBrowse link 1 65,540,808 65,543,708 RGD:1624291
RGD:1600115
negative regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 JBrowse link 5 86,387,238 86,554,108 RGD:1600115
RGD:1624291
G Kat2a lysine acetyltransferase 2A JBrowse link 10 88,611,586 88,619,558 RGD:1600115
RGD:1624291
G Kat2b lysine acetyltransferase 2B JBrowse link 9 4,440,982 4,492,949 RGD:1624291
G Mdm1 Mdm1 nuclear protein JBrowse link 7 61,165,652 61,200,865 RGD:1600115
RGD:1624291
G Rbm14 RNA binding motif protein 14 JBrowse link 1 220,048,740 220,067,124 RGD:1624291
RGD:1600115
G Trim37 tripartite motif-containing 37 JBrowse link 10 74,436,165 74,568,636 RGD:1624291
RGD:1600115
negative regulation of centriole-centriole cohesion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nek2 NIMA-related kinase 2 JBrowse link 13 110,511,546 110,524,750 RGD:1624291
G Nek2l1 NIMA (never in mitosis gene a)-related kinase 2-like 1 JBrowse link 8 15,940,934 15,942,589 RGD:13792537
negative regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccnf cyclin F JBrowse link 10 13,594,687 13,619,935 RGD:1624291
RGD:1600115
G Npm1 nucleophosmin 1 JBrowse link 10 18,080,949 18,091,062 RGD:1624291
G Nubp1 nucleotide binding protein 1 JBrowse link 10 5,333,378 5,343,949 RGD:1624291
RGD:1600115
G Tmem67 transmembrane protein 67 JBrowse link 5 25,666,138 25,721,056 RGD:8554306
RGD:1624291
RGD:1600115
positive regulation of centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cenpj centromere protein J JBrowse link 15 36,745,672 36,809,228 RGD:1600115
RGD:1624291
G Cep120 centrosomal protein 120 JBrowse link 18 48,658,495 48,720,570 RGD:1600115
RGD:1624291
G Cep295 centrosomal protein 295 JBrowse link 8 13,871,065 13,909,249 RGD:1600115
RGD:1624291
G Vps4b vacuolar protein sorting 4 homolog B JBrowse link 13 26,825,261 26,850,460 RGD:1624291
RGD:1600115
positive regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nup62 nucleoporin 62 JBrowse link 1 100,811,140 100,827,119 RGD:1624291
RGD:1600115
G Plk4 polo-like kinase 4 JBrowse link 2 127,686,911 127,705,518 RGD:1600115
RGD:1624291
positive regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cep120 centrosomal protein 120 JBrowse link 18 48,658,495 48,720,570 RGD:1624291
G Cep295 centrosomal protein 295 JBrowse link 8 13,871,065 13,909,249 RGD:1600115
RGD:1624291
G Npm1 nucleophosmin 1 JBrowse link 10 18,080,949 18,091,062 RGD:1624291
RGD:1600115
G Poc1a POC1 centriolar protein A JBrowse link 8 114,982,764 115,050,844 RGD:1624291
RGD:1600115
G Rock2 Rho-associated coiled-coil containing protein kinase 2 JBrowse link 6 42,180,864 42,289,910 RGD:1624291
RGD:1600115
positive regulation of mitotic centrosome separation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nsfl1c NSFL1 cofactor JBrowse link 3 146,980,923 147,005,478 RGD:1600115
RGD:1624291
G Ranbp1 RAN binding protein 1 JBrowse link 11 86,890,585 86,898,818 RGD:1624291
RGD:13792537
G Ubxn2b UBX domain protein 2B JBrowse link 5 19,285,368 19,314,199 RGD:1600115
RGD:1624291
regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alms1 ALMS1, centrosome and basal body associated protein JBrowse link 4 117,371,544 117,472,310 RGD:13792537
G Cenpj centromere protein J JBrowse link 15 36,745,672 36,809,228 RGD:1624291
G Cep295 centrosomal protein 295 JBrowse link 8 13,871,065 13,909,249 RGD:13792537
G Cep295nl CEP295 N-terminal like JBrowse link 10 107,363,511 107,381,280 RGD:13792537
G Cep76 centrosomal protein 76 JBrowse link 18 63,364,990 63,394,766 RGD:1624291
RGD:1600115
G LOC100302465 hypothetical LOC100302465 JBrowse link 1 206,324,763 206,417,143 RGD:13792537
G Npm1 nucleophosmin 1 JBrowse link 10 18,080,949 18,091,062 RGD:1624291
RGD:1600115
G Plk2 polo-like kinase 2 JBrowse link 2 41,911,143 41,916,901 RGD:1600115
RGD:1624291
G Spice1 spindle and centriole associated protein 1 JBrowse link 11 61,250,649 61,294,116 RGD:1624291
RGD:13792537
RGD:1600115
G Stil STIL, centriolar assembly protein JBrowse link 5 133,819,302 133,851,362 RGD:1624291
RGD:1600115
regulation of centriole-centriole cohesion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cep250 centrosomal protein 250 JBrowse link 3 151,508,366 151,544,631 RGD:1624291
RGD:1600115
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
regulation of centrosome cycle term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atf5 activating transcription factor 5 JBrowse link 1 100,807,821 100,812,410 RGD:1600115
RGD:1624291
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 JBrowse link 8 122,743,274 122,776,801 RGD:70723
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:10047173
G Mark4 microtubule affinity regulating kinase 4 JBrowse link 1 80,335,517 80,367,366 RGD:1600115
RGD:1624291
G Mcph1 microcephalin 1 JBrowse link 16 75,904,087 76,110,624 RGD:1624291
RGD:1600115
G Wdr62 WD repeat domain 62 JBrowse link 1 90,995,545 91,034,592 RGD:10047173
regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cep131 centrosomal protein 131 JBrowse link 10 109,243,240 109,267,636 RGD:1624291
RGD:13792537
G Chmp1a charged multivesicular body protein 1A JBrowse link 19 56,001,724 56,010,004 RGD:1624291
RGD:1600115
G Chmp1b charged multivesicular body protein 1B JBrowse link 18 62,923,620 62,926,150 RGD:1624291
G Chmp2a charged multivesicular body protein 2A JBrowse link 1 65,540,808 65,543,708 RGD:1624291
G Chmp2b charged multivesicular body protein 2B JBrowse link 11 2,666,405 2,692,213 RGD:1624291
RGD:1600115
G Chmp3 charged multivesicular body protein 3 JBrowse link 4 99,449,213 99,496,156 RGD:1624291
G Chmp4b charged multivesicular body protein 4B JBrowse link 3 150,188,275 150,227,453 RGD:1624291
G Chmp4c charged multivesicular body protein 4C JBrowse link 2 93,574,554 93,641,497 RGD:1600115
RGD:1624291
G Chmp5 charged multivesicular body protein 5 JBrowse link 5 57,267,312 57,284,455 RGD:1624291
RGD:1600115
G Chordc1 cysteine and histidine rich domain containing 1 JBrowse link 8 17,421,552 17,445,513 RGD:1624291
RGD:1600115
G Fbxw5 F-box and WD repeat domain containing 5 JBrowse link 3 2,726,705 2,731,213 RGD:1624291
RGD:1600115
G Gen1 GEN1 Holliday junction 5' flap endonuclease JBrowse link 6 36,910,064 36,940,868 RGD:1624291
RGD:1600115
G Npm1 nucleophosmin 1 JBrowse link 10 18,080,949 18,091,062 RGD:1624291
RGD:13792537
G Pdcd6ip programmed cell death 6 interacting protein JBrowse link 8 121,916,233 121,973,145 RGD:1624291
G Pkhd1 PKHD1, fibrocystin/polyductin JBrowse link 9 26,164,969 26,736,704 RGD:1624291
G Vps4b vacuolar protein sorting 4 homolog B JBrowse link 13 26,825,261 26,850,460 RGD:1624291
G Xpo1 exportin 1 JBrowse link 14 108,007,421 108,049,088 RGD:1624291
RGD:1600115
G Xrcc3 X-ray repair cross complementing 3 JBrowse link 6 136,366,917 136,380,751 RGD:1624291
RGD:1600115
regulation of mitotic centrosome separation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cep85 centrosomal protein 85 JBrowse link 5 152,359,693 152,406,530 RGD:1624291
G Chek1 checkpoint kinase 1 JBrowse link 8 39,181,162 39,201,588 RGD:1624291
RGD:1600115
G Kif11 kinesin family member 11 JBrowse link 1 256,035,866 256,088,299 RGD:1624291
RGD:1600115
G Map9 microtubule-associated protein 9 JBrowse link 2 181,331,426 181,367,245 RGD:1624291
RGD:1600115
G Nek2 NIMA-related kinase 2 JBrowse link 13 110,511,546 110,524,750 RGD:1624291
G Nek2l1 NIMA (never in mitosis gene a)-related kinase 2-like 1 JBrowse link 8 15,940,934 15,942,589 RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17928
    cellular process 16079
      cell cycle process 1129
        centrosome cycle 120
          centriole-centriole cohesion + 13
          centrosome duplication + 64
          centrosome separation + 14
          negative regulation of centrosome cycle + 13
          positive regulation of centrosome cycle + 12
          regulation of centriole-centriole cohesion + 4
          regulation of centrosome cycle + 58
Path 2
Term Annotations click to browse term
  biological_process 17928
    cellular component organization or biogenesis 6228
      cellular component organization 6055
        organelle organization 3647
          cytoskeleton organization 1328
            microtubule cytoskeleton organization 572
              microtubule organizing center organization 130
                centrosome cycle 120
                  centriole-centriole cohesion + 13
                  centrosome duplication + 64
                  centrosome separation + 14
                  negative regulation of centrosome cycle + 13
                  positive regulation of centrosome cycle + 12
                  regulation of centriole-centriole cohesion + 4
                  regulation of centrosome cycle + 58
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.