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ONTOLOGY REPORT - ANNOTATIONS


Term:centriole replication
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Accession:GO:0007099 term browser browse the term
Definition:The cell cycle process in which a daughter centriole is formed perpendicular to an existing centriole. An immature centriole contains a ninefold radially symmetric array of single microtubules; mature centrioles consist of a radial array of nine microtubule triplets, doublets, or singlets depending upon the species and cell type. Duplicated centrioles also become the ciliary basal body in cells that form cilia during G0.
Synonyms:exact_synonym: centriole duplication
 broad_synonym: microtubule basal body duplication
 related_synonym: ciliary basal body duplication
 alt_id: GO:0032054


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centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccp110 centriolar coiled-coil protein 110 JBrowse link 1 188,417,012 188,444,991 RGD:1624291
G Cdk2 cyclin dependent kinase 2 JBrowse link 7 3,124,953 3,132,533 RGD:1600115
RGD:1624291
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 JBrowse link 5 86,387,238 86,554,108 RGD:1600115
RGD:1624291
G Cenpj centromere protein J JBrowse link 15 36,745,672 36,809,228 RGD:1624291
G Cep135 centrosomal protein 135 JBrowse link 14 34,052,168 34,115,763 RGD:1624291
G Cep152 centrosomal protein 152 JBrowse link 3 117,822,799 117,894,856 RGD:1624291
G Cep63 centrosomal protein 63 JBrowse link 8 111,063,988 111,116,014 RGD:1600115
RGD:13792537
RGD:1624291
G Cep72 centrosomal protein 72 JBrowse link 1 31,834,977 31,864,938 RGD:1624291
G Cetn1 centrin 1 JBrowse link 18 785,972 786,674 RGD:13792537
G Cetn2 centrin 2 JBrowse link X 152,927,852 152,933,095 RGD:1624291
RGD:13792537
G Cetn4 centrin 4 JBrowse link 2 124,045,092 124,048,441 RGD:13792537
G Cntrob centrobin, centriole duplication and spindle assembly protein JBrowse link 10 55,901,929 55,927,121 RGD:1624291
RGD:13792537
G Deup1 deuterosome assembly protein 1 JBrowse link 8 14,094,742 14,157,232 RGD:13792537
G Ofd1 OFD1, centriole and centriolar satellite protein JBrowse link X 29,562,165 29,602,934 RGD:1624291
G Plk4 polo-like kinase 4 JBrowse link 2 127,686,911 127,705,518 RGD:1600115
RGD:1624291
G RGD1304728 similar to 4933427D14Rik protein JBrowse link 10 58,726,721 58,776,718 RGD:1600115
G Rttn rotatin JBrowse link 18 86,071,884 86,247,486 RGD:13792537
G Sass6 SAS-6 centriolar assembly protein JBrowse link 2 219,626,851 219,660,975 RGD:1624291
G Wdr62 WD repeat domain 62 JBrowse link 1 90,995,545 91,034,592 RGD:1624291
centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C2cd3 C2 domain containing 3 centriole elongation regulator JBrowse link 1 165,382,279 165,480,088 RGD:1624291
G Cenpj centromere protein J JBrowse link 15 36,745,672 36,809,228 RGD:1624291
negative regulation of centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chmp2a charged multivesicular body protein 2A JBrowse link 1 65,540,808 65,543,708 RGD:1624291
negative regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 JBrowse link 5 86,387,238 86,554,108 RGD:1600115
RGD:1624291
G Kat2a lysine acetyltransferase 2A JBrowse link 10 88,611,586 88,619,558 RGD:1624291
G Kat2b lysine acetyltransferase 2B JBrowse link 9 4,440,982 4,492,949 RGD:1624291
G Mdm1 Mdm1 nuclear protein JBrowse link 7 61,165,652 61,200,865 RGD:1600115
RGD:1624291
G Rbm14 RNA binding motif protein 14 JBrowse link 1 220,048,740 220,067,124 RGD:1624291
G Trim37 tripartite motif-containing 37 JBrowse link 10 74,436,165 74,568,636 RGD:1624291
positive regulation of centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cenpj centromere protein J JBrowse link 15 36,745,672 36,809,228 RGD:1624291
G Cep120 centrosomal protein 120 JBrowse link 18 48,658,495 48,720,570 RGD:1624291
G Cep295 centrosomal protein 295 JBrowse link 8 13,871,065 13,909,249 RGD:1600115
RGD:1624291
G Vps4b vacuolar protein sorting 4 homolog B JBrowse link 13 26,825,261 26,850,460 RGD:1624291
positive regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nup62 nucleoporin 62 JBrowse link 1 100,811,140 100,827,119 RGD:1624291
G Plk4 polo-like kinase 4 JBrowse link 2 127,686,911 127,705,518 RGD:1600115
RGD:1624291
regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alms1 ALMS1, centrosome and basal body associated protein JBrowse link 4 117,371,544 117,472,310 RGD:13792537
G Cenpj centromere protein J JBrowse link 15 36,745,672 36,809,228 RGD:1624291
G Cep295 centrosomal protein 295 JBrowse link 8 13,871,065 13,909,249 RGD:13792537
G Cep295nl CEP295 N-terminal like JBrowse link 10 107,363,511 107,381,280 RGD:13792537
G Cep76 centrosomal protein 76 JBrowse link 18 63,364,990 63,394,766 RGD:1624291
G LOC100302465 hypothetical LOC100302465 JBrowse link 1 206,324,763 206,417,143 RGD:13792537
G Npm1 nucleophosmin 1 JBrowse link 10 18,080,949 18,091,062 RGD:1624291
RGD:1600115
G Plk2 polo-like kinase 2 JBrowse link 2 41,911,143 41,916,901 RGD:1600115
RGD:1624291
G Spice1 spindle and centriole associated protein 1 JBrowse link 11 61,250,649 61,294,116 RGD:1624291
RGD:13792537
RGD:1600115
G Stil STIL, centriolar assembly protein JBrowse link 5 133,819,302 133,851,362 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19334
    cellular process 17238
      cell cycle process 1187
        centriole replication 38
          centriole elongation + 6
          negative regulation of centriole replication + 7
          positive regulation of centriole replication + 6
          regulation of centriole replication + 21
Path 2
Term Annotations click to browse term
  biological_process 19334
    cellular component organization or biogenesis 6441
      cellular component organization 6221
        organelle organization 3831
          cytoskeleton organization 1398
            microtubule cytoskeleton organization 607
              microtubule organizing center organization 141
                centrosome cycle 130
                  centrosome duplication 72
                    centriole replication 38
                      centriole elongation + 6
                      negative regulation of centriole replication + 7
                      positive regulation of centriole replication + 6
                      regulation of centriole replication + 21
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.