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ONTOLOGY REPORT - ANNOTATIONS


Term:mitotic centrosome separation
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Accession:GO:0007100 term browser browse the term
Definition:Separation of duplicated centrosome components at the beginning of mitosis. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle.


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mitotic centrosome separation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AURKA aurora kinase A JBrowse link 17 56,954,838 56,972,435 RGD:14298760
G KIF11 kinesin family member 11 JBrowse link 14 104,125,839 104,177,381 RGD:14298760
G NDE1 nudE neurodevelopment protein 1 JBrowse link 3 7,145,094 7,174,691 RGD:14298760
G NDEL1 nudE neurodevelopment protein 1 like 1 JBrowse link 12 53,553,897 53,640,470 RGD:14298760
G NUP62 nucleoporin 62 JBrowse link 6 54,921,627 54,945,705 RGD:14298760
positive regulation of mitotic centrosome separation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NSFL1C NSFL1 cofactor JBrowse link 17 33,869,487 33,890,873 RGD:14298760
G RANBP1 RAN binding protein 1 JBrowse link 14 51,494,258 51,500,420 RGD:14298760
G UBXN2B UBX domain protein 2B JBrowse link 4 74,405,876 74,437,650 RGD:14298760
regulation of mitotic centrosome separation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CEP85 centrosomal protein 85 JBrowse link 6 83,651,011 83,689,074 RGD:14298760
G KIF11 kinesin family member 11 JBrowse link 14 104,125,839 104,177,381 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15257
    cellular process 13567
      cell cycle process 878
        centrosome separation 10
          mitotic centrosome separation 9
            negative regulation of mitotic centrosome separation 0
            positive regulation of mitotic centrosome separation 3
            regulation of mitotic centrosome separation + 5
Path 2
Term Annotations click to browse term
  biological_process 15257
    cellular component organization or biogenesis 4693
      cellular component organization 4540
        organelle organization 2866
          cytoskeleton organization 1056
            microtubule cytoskeleton organization 470
              microtubule organizing center organization 107
                centrosome cycle 100
                  centrosome separation 10
                    mitotic centrosome separation 9
                      negative regulation of mitotic centrosome separation 0
                      positive regulation of mitotic centrosome separation 3
                      regulation of mitotic centrosome separation + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.